Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 206
- +2 vs. Q1 2025
- Shares held
- 83.1M
- +6.43M (+8.4%) vs. Q1 2025
- Total value
- $2.60B
- +$26.6M (+1.0%) vs. Q1 2025
- New holders
- 42
- 77 more added
- Sold out
- 40
- 55 more reduced
2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Janus Henderson Group PLC | 3,577,735 | $112.0M | 0.05% | +252,642+7.6% | Added |
| Braidwell LP | 3,605,029 | $112.8M | 3.86% | +895,154+33.0% | Added |
| Driehaus Capital Management LLC | 4,335,648 | $135.7M | 1.09% | −249,211−5.4% | Reduced |
| BlackRock, Inc. | 5,365,327 | $167.9M | 0.00% | +3,329,202+163.5% | Added |
| Avoro Capital Advisors LLC | 5,400,000 | $169.0M | 2.96% | −341,666−6.0% | Reduced |
| FMR LLC | 8,884,363 | $278.1M | 0.02% | +596,864+7.2% | Added |
| Samlyn Capital, LLC | 0 | $0 | 0.00% | −1,016,381−100.0% | Sold out |
| Logos Global Management LP | 0 | $0 | 0.00% | −650,000−100.0% | Sold out |
| Boxer Capital Management, LLC | 0 | $0 | 0.00% | −600,000−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −367,233−100.0% | Sold out |
| StemPoint Capital LP | 0 | $0 | 0.00% | −274,633−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −236,983−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −209,759−100.0% | Sold out |
| Nan Fung Group Holdings Ltd | 0 | $0 | 0.00% | −158,605−100.0% | Sold out |
| Bridger Management, LLC | 0 | $0 | 0.00% | −146,800−100.0% | Sold out |
| PFM Health Sciences, LP | 0 | $0 | 0.00% | −92,236−100.0% | Sold out |
| Lord, Abbett & Co. LLC | 0 | $0 | 0.00% | −87,981−100.0% | Sold out |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −69,603−100.0% | Sold out |
| Altium Capital Management LP | 0 | $0 | 0.00% | −60,251−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −42,000−100.0% | Sold out |
| Allostery Investments LP | 0 | $0 | 0.00% | −30,000−100.0% | Sold out |
| Sphera Funds Management Ltd. | 0 | $0 | 0.00% | −26,097−100.0% | Sold out |
| Atika Capital Management LLC | 0 | $0 | 0.00% | −24,000−100.0% | Sold out |
| Sanders Morris Harris LLC | 0 | $0 | 0.00% | −21,500−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −18,266−100.0% | Sold out |
| BIT Capital GmbH | 0 | $0 | 0.00% | −17,352−100.0% | Sold out |
| Occudo Quantitative Strategies LP | 0 | $0 | 0.00% | −16,975−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −12,508−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −11,949−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −11,372−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −10,511−100.0% | Sold out |
| Silverarc Capital Management, LLC | 0 | $0 | 0.00% | −10,121−100.0% | Sold out |
| EntryPoint Capital, LLC | 0 | $0 | 0.00% | −8,872−100.0% | Sold out |
| Vident Advisory, LLC | 0 | $0 | 0.00% | −6,574−100.0% | Sold out |
| Twinbeech Capital LP | 0 | $0 | 0.00% | −6,445−100.0% | Sold out |
| NEOS Investment Management LLC | 0 | $0 | 0.00% | −6,111−100.0% | Sold out |
| Tema ETFs LLC | 0 | $0 | 0.00% | −6,111−100.0% | Sold out |
| Guggenheim Capital LLC | 0 | $0 | 0.00% | −6,019−100.0% | Sold out |
| Coldstream Capital Management Inc | 0 | $0 | 0.00% | −648−100.0% | Sold out |
| Point72 Hong Kong Ltd | 0 | $0 | 0.00% | −329−100.0% | Sold out |
| Amundi | 0 | $0 | 0.00% | −114−100.0% | Sold out |
| Point72 (DIFC) Ltd | 0 | $0 | 0.00% | −66−100.0% | Sold out |
| Massmutual Trust Co FSB | 0 | $0 | 0.00% | −39−100.0% | Sold out |
| CIBC Private Wealth Group, LLC | 0 | $0 | 0.00% | −39−100.0% | Sold out |
| Continuum Advisory, LLC | 0 | $0 | 0.00% | −27−100.0% | Sold out |
| True Wealth Design, LLC | 0 | $0 | 0.00% | −9−100.0% | Sold out |
| Orion Portfolio Solutions, LLC | – | – | – | – | Not filed |
| Lindbrook Capital, LLC | – | – | – | – | Not filed |