Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2025
Institutional positions in Xenon Pharmaceuticals Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 206
- −3 vs. Q4 2024
- Shares held
- 76.7M
- +410.6K (+0.5%) vs. Q4 2024
- Total value
- $2.58B
- −$414.7M (−13.9%) vs. Q4 2024
- New holders
- 20
- 69 more added
- Sold out
- 23
- 73 more reduced
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Envestnet Asset Management Inc | 42,850 | $1.44M | 0.00% | −4,447−9.4% | Reduced |
| Neuberger Berman Group LLC | 44,852 | $1.50M | 0.00% | −48,109−51.8% | Reduced |
| Nebula Research & Development LLC | 46,561 | $1.56M | 0.14% | +26,201+128.7% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 47,457 | $1.59M | 0.01% | +7,081+17.5% | Added |
| Voya Investment Management LLC | 48,065 | $1.61M | 0.00% | −14,350−23.0% | Reduced |
| Mutual of America Capital Management LLC | 48,763 | $1.64M | 0.02% | +48,763 | New |
| State of New Jersey Common Pension Fund D | 50,417 | $1.69M | 0.01% | −3,616−6.7% | Reduced |
| Erste Asset Management GmbH | 50,000 | $1.71M | 0.02% | 00.0% | Unchanged |
| Deutsche Bank AG | 53,711 | $1.80M | 0.00% | 00.0% | Unchanged |
| Moore Capital Management, LP | 55,000 | $1.85M | 0.06% | 00.0% | Unchanged |
| Alps Advisors Inc | 55,332 | $1.86M | 0.01% | −6,316−10.2% | Reduced |
| California State Teachers Retirement System | 55,492 | $1.86M | 0.00% | 00.0% | Unchanged |
| Harbor Capital Advisors, Inc. | 56,591 | $1.90M | 0.09% | +6,773+13.6% | Added |
| Royal Bank of Canada | 59,366 | $1.99M | 0.00% | −702−1.2% | Reduced |
| Altium Capital Management LP | 60,251 | $2.02M | 5.87% | −227,749−79.1% | Reduced |
| Legal & General Group Plc | 60,406 | $2.03M | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 63,385 | $2.13M | 0.00% | +43,054+211.8% | Added |
| UBS Asset Management Americas Inc | 63,568 | $2.13M | 0.00% | −128,284−66.9% | Reduced |
| Wells Fargo & Company | 65,912 | $2.21M | 0.00% | +6,392+10.7% | Added |
| HighVista Strategies LLC | 66,788 | $2.24M | 0.86% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 69,597 | $2.33M | 0.00% | +68+0.1% | Added |
| Ally Bridge Group (NY) LLC | 69,603 | $2.34M | 2.11% | −59,688−46.2% | Reduced |
| Russell Investments Group, Ltd. | 75,341 | $2.53M | 0.00% | −138,355−64.7% | Reduced |
| Northern Trust Corp | 81,024 | $2.72M | 0.00% | +15,241+23.2% | Added |
| Nicholas Investment Partners, LP | 86,968 | $2.92M | 0.30% | +72,310+493.3% | Added |
| Lord, Abbett & Co. LLC | 87,981 | $2.95M | 0.01% | −106,990−54.9% | Reduced |
| PFM Health Sciences, LP | 92,236 | $3.09M | 0.24% | −24,762−21.2% | Reduced |
| State of Wisconsin Investment Board | 97,149 | $3.26M | 0.01% | +565+0.6% | Added |
| Bamco Inc | 100,100 | $3.36M | 0.01% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 103,624 | $3.48M | 0.00% | +11,274+12.2% | Added |
| UBS Group AG | 105,333 | $3.53M | 0.00% | +98,628+1,471.0% | Added |
| Algert Global LLC | 123,415 | $4.14M | 0.10% | −118,002−48.9% | Reduced |
| Swiss National Bank | 125,600 | $4.21M | 0.00% | −1,000−0.8% | Reduced |
| ADAR1 Capital Management, LLC | 127,548 | $4.28M | 0.82% | +77,001+152.3% | Added |
| Morgan Stanley | 129,491 | $4.34M | 0.00% | +61,429+90.3% | Added |
| Bank of America Corp | 136,569 | $4.58M | 0.00% | +29,663+27.7% | Added |
| Schroder Investment Management Group | 137,221 | $4.70M | 0.00% | −39,453−22.3% | Reduced |
| New York State Common Retirement Fund | 142,372 | $4.78M | 0.01% | +9,851+7.4% | Added |
| Bridger Management, LLC | 146,800 | $4.93M | 2.45% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 152,188 | $5.11M | 0.01% | +65,215+75.0% | Added |
| Renaissance Technologies LLC | 154,700 | $5.19M | 0.01% | +141,000+1,029.2% | Added |
| Nan Fung Group Holdings Ltd | 158,605 | $5.32M | 4.34% | +51,925+48.7% | Added |
| Parkman Healthcare Partners LLC | 174,576 | $5.86M | 0.69% | −18,428−9.5% | Reduced |
| AXA S.A. | 175,350 | $5.88M | 0.02% | −12,446−6.6% | Reduced |
| Granahan Investment Management Inc | 183,808 | $6.17M | 0.31% | +1,475+0.8% | Added |
| Invesco Ltd. | 205,763 | $6.90M | 0.00% | −3,791−1.8% | Reduced |
| Point72 Asset Management, L.P. | 209,759 | $7.04M | 0.02% | +209,759 | New |
| Dimensional Fund Advisors LP | 214,860 | $7.21M | 0.00% | −45,110−17.4% | Reduced |
| Avidity Partners Management LP | 229,000 | $7.68M | 1.58% | −245,000−51.7% | Reduced |
| DnB Asset Management AS | 229,482 | $7.70M | 0.04% | +26,239+12.9% | Added |
| Federated Hermes, Inc. | 232,500 | $7.80M | 0.02% | −326,000−58.4% | Reduced |
| Millennium Management LLC | 234,056 | $7.85M | 0.01% | −111,984−32.4% | Reduced |
| Two Sigma Investments, LP | 236,983 | $7.95M | 0.02% | −36,369−13.3% | Reduced |
| Assenagon Asset Management S.A. | 241,206 | $8.09M | 0.01% | +2,684+1.1% | Added |
| Great Point Partners LLC | 245,272 | $8.23M | 4.47% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 251,147 | $8.43M | 0.00% | +204,550+439.0% | Added |
| Balyasny Asset Management LLC | 267,142 | $8.96M | 0.02% | +82,562+44.7% | Added |
| DAFNA Capital Management LLC | 273,739 | $9.18M | 2.60% | 00.0% | Unchanged |
| StemPoint Capital LP | 274,633 | $9.21M | 2.94% | −101,212−26.9% | Reduced |
| Two Sigma Advisers, LP | 298,800 | $10.0M | 0.02% | +1000.0% | Added |
| MPM Oncology Impact Management LP | 303,398 | $10.2M | 1.75% | +106,186+53.8% | Added |
| State Street Corp | 305,620 | $10.3M | 0.00% | +16,898+5.9% | Added |
| Perceptive Advisors LLC | 325,324 | $10.9M | 0.39% | 00.0% | Unchanged |
| Vanguard Group Inc | 336,514 | $11.3M | 0.00% | −6,265−1.8% | Reduced |
| Baker Bros. Advisors LP | 347,408 | $11.7M | 0.13% | −646,271−65.0% | Reduced |
| Alyeska Investment Group, L.P. | 367,233 | $12.3M | 0.05% | +78,390+27.1% | Added |
| Standard Life Aberdeen plc | 404,154 | $13.6M | 0.03% | +120,255+42.4% | Added |
| Saturn V Capital Management LLC | 413,711 | $13.9M | 7.00% | +91,241+28.3% | Added |
| Goldman Sachs Group Inc | 442,732 | $14.9M | 0.00% | +32,486+7.9% | Added |
| Candriam Luxembourg S.C.A. | 454,650 | $15.3M | 0.10% | −37,531−7.6% | Reduced |
| Franklin Resources Inc | 491,120 | $16.5M | 0.00% | −84,470−14.7% | Reduced |
| Fiera Capital Corp | 529,442 | $17.8M | 0.06% | −6,445−1.2% | Reduced |
| Boxer Capital Management, LLC | 600,000 | $20.1M | 6.05% | 00.0% | Unchanged |
| First Light Asset Management, LLC | 627,904 | $21.1M | 2.41% | −532,676−45.9% | Reduced |
| Logos Global Management LP | 650,000 | $21.8M | 3.88% | +650,000 | New |
| Loomis Sayles & Co L P | 673,011 | $22.6M | 0.03% | −14,134−2.1% | Reduced |
| First Turn Management, LLC | 683,451 | $22.9M | 4.62% | −1,535−0.2% | Reduced |
| Citadel Advisors LLC | 687,088 | $23.1M | 0.02% | +359,785+109.9% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 703,795 | $23.6M | 0.06% | +40,091+6.0% | Added |
| Siren, L.L.C. | 732,761 | $24.6M | 1.39% | −11,008−1.5% | Reduced |
| TimesSquare Capital Management, LLC | 745,551 | $25.0M | 0.40% | −103,299−12.2% | Reduced |
| Marshall Wace, LLP | 758,145 | $25.4M | 0.03% | −141,573−15.7% | Reduced |
| Jennison Associates LLC | 776,693 | $26.1M | 0.02% | −24,860−3.1% | Reduced |
| T. Rowe Price Investment Management, Inc. | 796,986 | $26.7M | 0.02% | −640,845−44.6% | Reduced |
| Rock Springs Capital Management LP | 931,681 | $31.3M | 1.79% | −320,178−25.6% | Reduced |
| OrbiMed Advisors LLC | 947,877 | $31.8M | 0.76% | 00.0% | Unchanged |
| Deep Track Capital, LP | 1,000,000 | $33.5M | 1.09% | +830,868+491.3% | Added |
| Samlyn Capital, LLC | 1,016,381 | $34.1M | 0.56% | −1,457−0.1% | Reduced |
| Vestal Point Capital, LP | 1,300,000 | $43.6M | 3.11% | +490,000+60.5% | Added |
| Affinity Asset Advisors, LLC | 1,328,175 | $44.6M | 6.98% | +166,938+14.4% | Added |
| Alliancebernstein L.P. | 1,329,386 | $44.6M | 0.02% | −113,794−7.9% | Reduced |
| JPMorgan Chase & Co | 1,357,602 | $45.5M | 0.00% | +707+0.1% | Added |
| Westfield Capital Management Co LP | 1,391,370 | $46.7M | 0.23% | +234,181+20.2% | Added |
| Pictet Asset Management Holding SA | 1,477,617 | $49.6M | 0.06% | −18,894−1.3% | Reduced |
| Adage Capital Partners GP, L.L.C. | 1,914,749 | $64.2M | 0.12% | +51,276+2.8% | Added |
| BlackRock, Inc. | 2,036,125 | $68.3M | 0.00% | −69,111−3.3% | Reduced |
| Capital World Investors | 2,224,715 | $74.6M | 0.01% | −69,822−3.0% | Reduced |
| Commodore Capital LP | 2,325,000 | $78.0M | 5.75% | −415,000−15.1% | Reduced |
| Polar Capital Holdings Plc | 2,623,039 | $88.0M | 0.54% | −74,618−2.8% | Reduced |
| Braidwell LP | 2,709,875 | $90.9M | 3.20% | −204,089−7.0% | Reduced |