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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2022

Institutional positions in Xenon Pharmaceuticals Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
154
+3 vs. Q2 2022
Shares held
57.9M
+880.8K (+1.5%) vs. Q2 2022
Total value
$2.09B
+$355.6M (+20.5%) vs. Q2 2022
New holders
26
58 more added
Sold out
23
42 more reduced

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 154 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ3 2022: $2.09B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q2 2022.

Institutions holding XENE in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Swiss National Bank108,400$3.91M0.00%+600+0.6%Added
Ensign Peak Advisors, Inc113,480$4.10M0.01%+57,189+101.6%Added
Nan Fung Group Holdings Ltd114,380$4.13M2.64%00.0%Unchanged
Putnam Investments LLC129,284$4.67M0.01%+129,284New
Tri Locum Partners LP134,331$4.85M1.38%−32,068−19.3%Reduced
Alliancebernstein L.P.142,726$5.15M0.00%−287,234−66.8%Reduced
Balyasny Asset Management LLC147,355$5.32M0.02%+147,355New
EAM Global Investors LLC154,485$5.58M1.48%+3,996+2.7%Added
Morgan Stanley158,452$5.72M0.00%−839,620−84.1%Reduced
Ikarian Capital, LLC160,486$5.79M2.89%−78,955−33.0%Reduced
State Street Corp170,371$6.15M0.00%−26,850−13.6%Reduced
Vanguard Group Inc185,192$6.69M0.00%+1,347+0.7%Added
AXA S.A.191,836$6.93M0.03%+485+0.3%Added
State of Wisconsin Investment Board217,474$7.85M0.02%+171,651+374.6%Added
Parkman Healthcare Partners LLC222,597$8.04M2.28%−71,962−24.4%Reduced
Janus Henderson Group PLC233,834$8.43M0.01%−42,840−15.5%Reduced
Silverarc Capital Management, LLC245,992$8.88M3.77%+13,362+5.7%Added
Eversept Partners, LP259,612$9.37M1.11%−206,299−44.3%Reduced
Acuta Capital Partners, LLC272,500$9.84M4.38%00.0%Unchanged
Granahan Investment Management Inc299,855$10.8M0.35%+15,083+5.3%Added
Dimensional Fund Advisors LP342,031$12.3M0.00%+167,069+95.5%Added
DAFNA Capital Management LLC375,223$13.5M3.64%−63,400−14.5%Reduced
Woodline Partners LP404,359$14.6M0.21%+175,431+76.6%Added
D. E. Shaw & Co., Inc.409,563$14.8M0.03%+83,021+25.4%Added
Bank of New York Mellon Corp437,645$15.8M0.00%−125,542−22.3%Reduced
Goldman Sachs Group Inc465,265$16.8M0.00%+168,951+57.0%Added
Logos Global Management LP500,000$18.1M2.23%+500,000New
Millennium Management LLC560,349$20.2M0.03%+67,658+13.7%Added
Boxer Capital, LLC600,000$21.7M1.22%00.0%Unchanged
Eventide Asset Management, LLC641,200$23.1M0.46%+171,500+36.5%Added
Adage Capital Partners GP, L.L.C.675,000$24.4M0.06%+45,000+7.1%Added
Baker Bros. Advisors LP751,639$27.1M0.18%00.0%Unchanged
Candriam Luxembourg S.C.A.760,884$27.5M0.19%−102,256−11.8%Reduced
Great Point Partners LLC850,000$30.7M7.39%−254,334−23.0%Reduced
BVF Inc901,095$32.5M1.34%−696,871−43.6%Reduced
BlackRock Inc.1,042,529$37.6M0.00%+174,239+20.1%Added
OrbiMed Advisors LLC1,137,300$41.1M0.82%−191,900−14.4%Reduced
Citadel Advisors LLC1,142,002$41.2M0.05%−506,037−30.7%Reduced
Rock Springs Capital Management LP1,155,961$41.7M1.08%+32,357+2.9%Added
Samlyn Capital, LLC1,289,233$46.5M0.89%+172,797+15.5%Added
Commodore Capital LP1,594,932$57.6M9.26%00.0%Unchanged
Point72 Asset Management, L.P.1,640,072$59.2M0.26%+738,566+81.9%Added
Capital International Investors1,642,508$59.3M0.02%+60,000+3.8%Added
Holocene Advisors, LP1,829,152$66.0M0.42%00.0%Unchanged
Lord, Abbett & Co. LLC1,913,861$69.1M0.25%+56,265+3.0%Added
Perceptive Advisors LLC2,122,535$76.6M2.23%00.0%Unchanged
Capital World Investors2,274,974$82.1M0.02%00.0%Unchanged
Pictet Asset Management SA2,287,365$82.6M0.12%+467,889+25.7%Added
Redmile Group, LLC2,370,614$85.6M3.32%+731,270+44.6%Added
Polar Capital Holdings Plc2,662,722$96.1M0.78%+122,663+4.8%Added
Marshall Wace, LLP2,811,095$101.5M0.25%+820,723+41.2%Added
Driehaus Capital Management LLC4,504,020$162.6M2.46%+112,982+2.6%Added
FMR LLC4,669,759$168.6M0.02%+97,391+2.1%Added
Avoro Capital Advisors LLC4,900,000$176.9M3.27%00.0%Unchanged
Avidity Partners Management LP0$00.00%−450,000−100.0%Sold out
Polar Asset Management Partners Inc.0$00.00%−124,000−100.0%Sold out
Integral Health Asset Management, LLC0$00.00%−97,281−100.0%Sold out
Monashee Investment Management LLC0$00.00%−85,000−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−73,737−100.0%Sold out
Maven Securities LTD0$00.00%−55,645−100.0%Sold out
Altshuler Shaham Ltd0$00.00%−42,000−100.0%Sold out
Cinctive Capital Management LP0$00.00%−41,073−100.0%Sold out
Pura Vida Investments, LLC0$00.00%−40,002−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−34,389−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−31,332−100.0%Sold out
VR Adviser, LLC0$00.00%−30,000−100.0%Sold out
Jefferies Group LLC0$00.00%−27,828−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−20,336−100.0%Sold out
Sio Capital Management, LLC0$00.00%−16,368−100.0%Sold out
Jupiter Asset Management Ltd0$00.00%−11,138−100.0%Sold out
De Burlo Group Inc0$00.00%−10,000−100.0%Sold out
Laurion Capital Management LP0$00.00%−10,000−100.0%Sold out
Pinz Capital Management, LP0$00.00%−10,000−100.0%Sold out
Sandia Investment Management LP0$00.00%−9,900−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−7,324−100.0%Sold out
State of Wyoming0$00.00%−64−100.0%Sold out
Patriot Financial Group Insurance Agency, LLC0$00.00%−35−100.0%Sold out