Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 2 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2021
Institutional positions in Xenon Pharmaceuticals Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 130
- +14 vs. Q3 2021
- Shares held
- 47.7M
- +14.0M (+41.6%) vs. Q3 2021
- Total value
- $1.49B
- +$974.8M (+189.3%) vs. Q3 2021
- New holders
- 38
- 50 more added
- Sold out
- 24
- 27 more reduced
2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Legal & General Group Plc | 10,513 | $328.0K | 0.00% | +3,765+55.8% | Added |
| Difesa Capital Management, LP | 10,000 | $312.0K | 0.23% | +10,000 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 9,565 | $299.0K | 0.00% | +5,364+127.7% | Added |
| Engineers Gate Manager LP | 9,083 | $284.0K | 0.01% | −5,067−35.8% | Reduced |
| New York State Common Retirement Fund | 8,100 | $253.0K | 0.00% | +8,100 | New |
| Victory Capital Management Inc | 7,545 | $236.0K | 0.00% | +7,545 | New |
| ProShare Advisors LLC | 7,266 | $227.0K | 0.00% | +7,266 | New |
| Twinbeech Capital LP | 6,878 | $215.0K | 0.01% | +6,878 | New |
| Virtus ETF Advisers LLC | 6,439 | $201.0K | 0.08% | −5,055−44.0% | Reduced |
| Aquatic Capital Management LLC | 5,400 | $169.0K | 0.33% | +5,400 | New |
| JPMorgan Chase & Co | 4,775 | $149.0K | 0.00% | +1,761+58.4% | Added |
| Amundi | 4,528 | $132.0K | 0.00% | +4,528 | New |
| Macquarie Group Ltd | 3,514 | $110.0K | 0.00% | 00.0% | Unchanged |
| Eaton Vance Management | 2,500 | $78.0K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 2,301 | $72.0K | 0.00% | −328−12.5% | Reduced |
| Proequities, Inc. | 2,000 | $62.0K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 1,857 | $58.0K | 0.00% | +753+68.2% | Added |
| UBS Group AG | 1,777 | $56.0K | 0.00% | +755+73.9% | Added |
| Turim 21 Investimentos Ltda. | 1,466 | $46.0K | 0.02% | +1,466 | New |
| IFP Advisors, Inc | 1,000 | $31.0K | 0.00% | 00.0% | Unchanged |
| High Net Worth Advisory Group LLC | 1,000 | $31.0K | 0.01% | +1,000 | New |
| Tower Research Capital LLC (TRC) | 646 | $20.0K | 0.00% | −667−50.8% | Reduced |
| Cutler Group LP | 600 | $18.0K | 0.00% | −1,293−68.3% | Reduced |
| Leonteq Securities AG | 530 | $16.6K | 0.00% | +530 | New |
| Jefferies Group LLC | 454 | $14.2K | 0.00% | +454 | New |
| Brown Brothers Harriman & Co | 294 | $9.00K | 0.00% | +294 | New |
| Daiwa Securities Group Inc. | 141 | $4.00K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 100 | $3.00K | 0.00% | −275−73.3% | Reduced |
| BNP Paribas Arbitrage, SA | 80 | $2.50K | 0.00% | −422−84.1% | Reduced |
| State of Wyoming | 40 | $1.00K | 0.00% | −2−4.8% | Reduced |
| NEA Management Company, LLC | 0 | $0 | 0.00% | −992,107−100.0% | Sold out |
| Sphera Funds Management Ltd. | 0 | $0 | 0.00% | −373,510−100.0% | Sold out |
| Altium Capital Management LP | 0 | $0 | 0.00% | −216,000−100.0% | Sold out |
| Woodline Partners LP | 0 | $0 | 0.00% | −199,984−100.0% | Sold out |
| Monashee Investment Management LLC | 0 | $0 | 0.00% | −180,000−100.0% | Sold out |
| Tekla Capital Management LLC | 0 | $0 | 0.00% | −169,030−100.0% | Sold out |
| Fred Alger Management, LLC | 0 | $0 | 0.00% | −105,989−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −82,967−100.0% | Sold out |
| Endurant Capital Management LP | 0 | $0 | 0.00% | −62,743−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −30,607−100.0% | Sold out |
| M&G Investment Management Ltd | 0 | $0 | 0.00% | −34,103−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −26,279−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −23,213−100.0% | Sold out |
| Crestline Management, LP | 0 | $0 | 0.00% | −20,417−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −11,866−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −10,357−100.0% | Sold out |
| Interwest Venture Management Co | 0 | $0 | 0.00% | −8,293−100.0% | Sold out |
| Deutsche Bank AG | 0 | $0 | 0.00% | −7,987−100.0% | Sold out |
| Accel Wealth Management | 0 | $0 | 0.00% | −3,900−100.0% | Sold out |
| Captrust Financial Advisors | 0 | $0 | 0.00% | −3,000−100.0% | Sold out |
| Lindbrook Capital, LLC | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Penserra Capital Management LLC | 0 | $0 | 0.00% | −940−100.0% | Sold out |
| Carmichael Hill & Associates, Inc. | 0 | $0 | 0.00% | −80−100.0% | Sold out |
| Global Wealth Management Investment Advisory, Inc. | 0 | $0 | 0.00% | −20−100.0% | Sold out |
| Marshall Wace North America L.P. | – | – | – | – | Not filed |
| Knott David M | – | – | – | – | Not filed |