Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2021
Institutional positions in Xenon Pharmaceuticals Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 130
- +14 vs. Q3 2021
- Shares held
- 47.7M
- +14.0M (+41.6%) vs. Q3 2021
- Total value
- $1.49B
- +$974.8M (+189.3%) vs. Q3 2021
- New holders
- 38
- 50 more added
- Sold out
- 24
- 27 more reduced
2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| State of Wyoming | 40 | $1.00K | 0.00% | −2−4.8% | Reduced |
| BNP Paribas Arbitrage, SA | 80 | $2.50K | 0.00% | −422−84.1% | Reduced |
| Advisor Group Holdings, Inc. | 100 | $3.00K | 0.00% | −275−73.3% | Reduced |
| Daiwa Securities Group Inc. | 141 | $4.00K | 0.00% | 00.0% | Unchanged |
| Brown Brothers Harriman & Co | 294 | $9.00K | 0.00% | +294 | New |
| Jefferies Group LLC | 454 | $14.2K | 0.00% | +454 | New |
| Leonteq Securities AG | 530 | $16.6K | 0.00% | +530 | New |
| Cutler Group LP | 600 | $18.0K | 0.00% | −1,293−68.3% | Reduced |
| Tower Research Capital LLC (TRC) | 646 | $20.0K | 0.00% | −667−50.8% | Reduced |
| IFP Advisors, Inc | 1,000 | $31.0K | 0.00% | 00.0% | Unchanged |
| High Net Worth Advisory Group LLC | 1,000 | $31.0K | 0.01% | +1,000 | New |
| Turim 21 Investimentos Ltda. | 1,466 | $46.0K | 0.02% | +1,466 | New |
| UBS Group AG | 1,777 | $56.0K | 0.00% | +755+73.9% | Added |
| Great West Life Assurance Co | 1,857 | $58.0K | 0.00% | +753+68.2% | Added |
| Proequities, Inc. | 2,000 | $62.0K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 2,301 | $72.0K | 0.00% | −328−12.5% | Reduced |
| Eaton Vance Management | 2,500 | $78.0K | 0.00% | 00.0% | Unchanged |
| Macquarie Group Ltd | 3,514 | $110.0K | 0.00% | 00.0% | Unchanged |
| Amundi | 4,528 | $132.0K | 0.00% | +4,528 | New |
| JPMorgan Chase & Co | 4,775 | $149.0K | 0.00% | +1,761+58.4% | Added |
| Aquatic Capital Management LLC | 5,400 | $169.0K | 0.33% | +5,400 | New |
| Virtus ETF Advisers LLC | 6,439 | $201.0K | 0.08% | −5,055−44.0% | Reduced |
| Twinbeech Capital LP | 6,878 | $215.0K | 0.01% | +6,878 | New |
| ProShare Advisors LLC | 7,266 | $227.0K | 0.00% | +7,266 | New |
| Victory Capital Management Inc | 7,545 | $236.0K | 0.00% | +7,545 | New |
| New York State Common Retirement Fund | 8,100 | $253.0K | 0.00% | +8,100 | New |
| Engineers Gate Manager LP | 9,083 | $284.0K | 0.01% | −5,067−35.8% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 9,565 | $299.0K | 0.00% | +5,364+127.7% | Added |
| Difesa Capital Management, LP | 10,000 | $312.0K | 0.23% | +10,000 | New |
| Legal & General Group Plc | 10,513 | $328.0K | 0.00% | +3,765+55.8% | Added |
| Arizona State Retirement System | 10,679 | $334.0K | 0.00% | +10,679 | New |
| Supplemental Annuity Collective Trust of NJ | 11,000 | $344.0K | 0.11% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 11,014 | $344.0K | 0.00% | +11,014 | New |
| Stifel Financial Corp | 11,484 | $358.0K | 0.00% | +556+5.1% | Added |
| DekaBank Deutsche Girozentrale | 11,300 | $359.0K | 0.00% | +300+2.7% | Added |
| Sender Co & Partners, Inc. | 12,215 | $382.0K | 0.24% | +12,215 | New |
| Brown Advisory Inc | 12,911 | $403.0K | 0.00% | +12,911 | New |
| Guggenheim Capital LLC | 13,684 | $427.0K | 0.00% | +3,609+35.8% | Added |
| Qube Research & Technologies Ltd | 14,304 | $447.0K | 0.00% | +14,304 | New |
| Cubist Systematic Strategies, LLC | 14,541 | $454.0K | 0.00% | +6,653+84.3% | Added |
| Elmwood Wealth Management, Inc. | 18,080 | $565.0K | 0.27% | +18,080 | New |
| Boothbay Fund Management, LLC | 18,376 | $574.0K | 0.02% | −32,948−64.2% | Reduced |
| Handelsbanken Fonder AB | 20,700 | $647.0K | 0.00% | +20,700 | New |
| Susquehanna Fundamental Investments, LLC | 20,866 | $652.0K | 0.02% | 00.0% | Unchanged |
| Royal Bank of Canada | 24,313 | $760.0K | 0.00% | −1,000−4.0% | Reduced |
| Sanders Morris Harris LLC | 24,500 | $771.0K | 0.13% | 00.0% | Unchanged |
| Credit Suisse AG | 24,904 | $777.0K | 0.00% | +6,206+33.2% | Added |
| NJ State Employees Deferred Compensation Plan | 25,000 | $781.0K | 0.10% | 00.0% | Unchanged |
| Granite Point Capital Management, L.P. | 25,000 | $781.0K | 0.30% | +25,000 | New |
| Tri Locum Partners LP | 25,043 | $782.0K | 0.31% | −239,091−90.5% | Reduced |
| Shell Asset Management Co | 25,329 | $791.0K | 0.02% | +164+0.7% | Added |
| International Biotechnology Trust PLC | 25,500 | $797.0K | 0.18% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 28,062 | $876.7K | 0.00% | +28,062 | New |
| Geode Capital Management, LLC | 28,198 | $880.0K | 0.00% | +6,548+30.2% | Added |
| Jump Financial, LLC | 31,300 | $978.0K | 0.06% | +31,300 | New |
| California State Teachers Retirement System | 33,508 | $1.05M | 0.00% | +10,178+43.6% | Added |
| Scotia Capital Inc. | 33,696 | $1.05M | 0.01% | −3,440−9.3% | Reduced |
| Erste Asset Management GmbH | 35,000 | $1.10M | 0.02% | +35,000 | New |
| Gyon Technologies Capital Management, LP | 36,279 | $1.13M | 0.21% | +23,445+182.7% | Added |
| Teacher Retirement System of Texas | 37,028 | $1.16M | 0.01% | +37,028 | New |
| Ensign Peak Advisors, Inc | 37,115 | $1.16M | 0.00% | +5,600+17.8% | Added |
| Nuveen Asset Management, LLC | 41,884 | $1.31M | 0.00% | +12,586+43.0% | Added |
| Bamco Inc | 42,000 | $1.31M | 0.00% | +42,000 | New |
| Cinctive Capital Management LP | 42,303 | $1.32M | 0.06% | +42,303 | New |
| Bank of America Corp | 42,798 | $1.34M | 0.00% | +28,411+197.5% | Added |
| Voloridge Investment Management, LLC | 47,920 | $1.50M | 0.01% | +47,920 | New |
| Pura Vida Investments, LLC | 48,502 | $1.51M | 0.16% | −1,498−3.0% | Reduced |
| CIBC World Markets Inc. | 49,634 | $1.55M | 0.01% | +49,634 | New |
| Northern Trust Corp | 50,596 | $1.58M | 0.00% | +12,746+33.7% | Added |
| Russell Investments Group, Ltd. | 52,171 | $1.63M | 0.00% | +52,171 | New |
| Altshuler Shaham Ltd | 53,600 | $1.67M | 0.04% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 58,321 | $1.82M | 0.00% | +43,621+296.7% | Added |
| Alps Advisors Inc | 59,702 | $1.86M | 0.02% | +9,287+18.4% | Added |
| HighVista Strategies LLC | 62,906 | $1.97M | 1.56% | −12,140−16.2% | Reduced |
| Allianz Asset Management GmbH | 69,905 | $2.19M | 0.00% | +69,905 | New |
| Walleye Capital LLC | 71,984 | $2.25M | 0.07% | +71,984 | New |
| Polar Asset Management Partners Inc. | 78,300 | $2.45M | 0.03% | +78,300 | New |
| Knott David M Jr | 86,488 | $2.70M | 1.02% | +86,488 | New |
| Swiss National Bank | 87,400 | $2.73M | 0.00% | +24,000+37.9% | Added |
| Schonfeld Strategic Advisors LLC | 88,900 | $2.78M | 0.03% | −31,221−26.0% | Reduced |
| Millennium Management LLC | 90,621 | $2.83M | 0.00% | −145,598−61.6% | Reduced |
| Ghost Tree Capital, LLC | 100,000 | $3.12M | 1.20% | −690,000−87.3% | Reduced |
| Silverarc Capital Management, LLC | 100,000 | $3.12M | 1.40% | +80,568+414.6% | Added |
| Two Sigma Advisers, LP | 126,600 | $3.96M | 0.01% | −49,200−28.0% | Reduced |
| Affinity Asset Advisors, LLC | 150,500 | $4.70M | 2.01% | +100,500+201.0% | Added |
| Vanguard Group Inc | 153,366 | $4.79M | 0.00% | +46,174+43.1% | Added |
| State Street Corp | 161,249 | $5.04M | 0.00% | +13,802+9.4% | Added |
| Altrinsic Global Advisors LLC | 170,000 | $5.31M | 0.17% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 171,394 | $5.35M | 0.00% | +75,409+78.6% | Added |
| Ikarian Capital, LLC | 179,138 | $5.60M | 1.60% | −198,300−52.5% | Reduced |
| AXA S.A. | 195,048 | $6.09M | 0.02% | +35,405+22.2% | Added |
| Nan Fung Group Holdings Ltd | 197,880 | $6.18M | 1.83% | 00.0% | Unchanged |
| Eversept Partners, LP | 209,519 | $6.55M | 0.54% | +209,519 | New |
| Granahan Investment Management Inc | 217,301 | $6.79M | 0.14% | +133,447+159.1% | Added |
| Acuta Capital Partners, LLC | 225,000 | $7.03M | 2.95% | −192,409−46.1% | Reduced |
| Two Sigma Investments, LP | 278,343 | $8.70M | 0.02% | +108,667+64.0% | Added |
| Dimensional Fund Advisors LP | 291,946 | $9.12M | 0.00% | +140,749+93.1% | Added |
| Invesco Ltd. | 294,100 | $9.19M | 0.00% | +294,100 | New |
| Alliancebernstein L.P. | 294,098 | $9.19M | 0.00% | +30,995+11.8% | Added |
| Parkman Healthcare Partners LLC | 360,502 | $11.3M | 2.55% | +49,295+15.8% | Added |