Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 346
- +27 vs. Q1 2026
- Shares held
- 75.9M
- −104.9K (−0.1%) vs. Q1 2026
- Total value
- $9.30B
- +$1.30B (+16.2%) vs. Q1 2026
- New holders
- 62
- 141 more added
- Sold out
- 35
- 90 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| State Board of Administration of Florida Retirement System | 16,303 | $2.00M | 0.00% | 00.0% | Unchanged |
| Phocas Financial Corp. | 16,378 | $2.01M | 0.28% | +16,378 | New |
| Yousif Capital Management, LLC | 16,483 | $2.02M | 0.02% | +251+1.5% | Added |
| State of New Jersey Common Pension Fund D | 16,506 | $2.02M | 0.01% | −586−3.4% | Reduced |
| Jane Street Group, LLC | 16,882 | $2.07M | 0.00% | +13,275+368.0% | Added |
| Police & Firemen's Retirement System of New Jersey | 18,155 | $2.23M | 0.02% | +2,321+14.7% | Added |
| Gotham Asset Management, LLC | 18,663 | $2.29M | 0.01% | −2,492−11.8% | Reduced |
| SG Americas Securities, LLC | 19,080 | $2.34M | 0.00% | +983+5.4% | Added |
| Envestnet Asset Management Inc | 19,134 | $2.35M | 0.00% | +2,817+17.3% | Added |
| Erste Asset Management GmbH | 21,000 | $2.55M | 0.02% | +7,500+55.6% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 20,934 | $2.57M | 0.00% | +7,522+56.1% | Added |
| Handelsbanken Fonder AB | 21,400 | $2.62M | 0.01% | +1,500+7.5% | Added |
| Guggenheim Capital LLC | 21,800 | $2.67M | 0.02% | +6,520+42.7% | Added |
| Polen Capital Management LLC | 22,651 | $2.78M | 0.02% | −1,686−6.9% | Reduced |
| State of Tennessee, Treasury Department | 22,771 | $2.79M | 0.01% | −526−2.3% | Reduced |
| Artia Global Partners LP | 22,951 | $2.81M | 0.53% | +20+0.1% | Added |
| Intech Investment Management LLC | 24,056 | $2.95M | 0.03% | +11,050+85.0% | Added |
| Exchange Traded Concepts, LLC | 24,124 | $2.96M | 0.01% | +351+1.5% | Added |
| HighVista Strategies LLC | 24,460 | $3.00M | 0.68% | −9,392−27.7% | Reduced |
| Allspring Global Investments Holdings, LLC | 24,054 | $3.01M | 0.00% | −5,862−19.6% | Reduced |
| New York State Common Retirement Fund | 25,243 | $3.09M | 0.00% | +6,861+37.3% | Added |
| Brevan Howard Capital Management LP | 25,270 | $3.10M | 0.04% | +25,270 | New |
| Natixis Advisors, L.P. | 25,459 | $3.12M | 0.00% | +2,821+12.5% | Added |
| HSBC Holdings PLC | 25,952 | $3.20M | 0.00% | +24,045+1,260.9% | Added |
| Rafferty Asset Management, LLC | 26,099 | $3.20M | 0.01% | −20,653−44.2% | Reduced |
| Louisiana State Employees Retirement System | 26,500 | $3.25M | 0.05% | +400+1.5% | Added |
| Teachers Retirement System of the State of Kentucky | 26,528 | $3.25M | 0.02% | 00.0% | Unchanged |
| EAM Investors, LLC | 27,491 | $3.37M | 0.30% | −423−1.5% | Reduced |
| Schonfeld Strategic Advisors LLC | 28,072 | $3.44M | 0.02% | +28,072 | New |
| State of Alaska, Department of Revenue | 28,084 | $3.44M | 0.03% | −9,063−24.4% | Reduced |
| Pathstone Holdings, LLC | 28,187 | $3.46M | 0.01% | −65−0.2% | Reduced |
| Vanguard Global Advisers, LLC | 28,463 | $3.49M | 0.00% | +3,798+15.4% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 29,161 | $3.57M | 0.01% | +1,901+7.0% | Added |
| Illinois Municipal Retirement Fund | 29,211 | $3.58M | 0.04% | +615+2.2% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 31,377 | $3.84M | 0.00% | +773+2.5% | Added |
| State of Wisconsin Investment Board | 33,152 | $4.06M | 0.01% | +2,385+7.8% | Added |
| Birchview Capital, LP | 35,018 | $4.29M | 2.01% | +18+0.1% | Added |
| MetLife Investment Management | 35,792 | $4.39M | 0.02% | +3,993+12.6% | Added |
| Mutual of America Capital Management LLC | 36,252 | $4.44M | 0.04% | +29,527+439.1% | Added |
| Elmind Capital, LP | 38,000 | $4.66M | 1.17% | 00.0% | Unchanged |
| LMR Partners LLP | 38,000 | $4.66M | 0.03% | +7,150+23.2% | Added |
| Thrivent Financial for Lutherans | 39,697 | $4.87M | 0.01% | +472+1.2% | Added |
| EFG International AG | 40,501 | $4.96M | 0.09% | −9,585−19.1% | Reduced |
| OrbiMed Advisors LLC | 42,100 | $5.16M | 0.10% | 00.0% | Unchanged |
| Arrowstreet Capital, Limited Partnership | 44,529 | $5.46M | 0.00% | +44,529 | New |
| Caption Management, LLC | 45,000 | $5.52M | 0.19% | +45,000 | New |
| Seven Fleet Capital Management LP | 45,400 | $5.57M | 0.92% | +41,400+1,035.0% | Added |
| Silvercrest Asset Management Group LLC | 45,668 | $5.60M | 0.04% | −2,263−4.7% | Reduced |
| Great West Life Assurance Co | 48,045 | $5.88M | 0.01% | +605+1.3% | Added |
| Northwestern Mutual Wealth Management Co | 48,894 | $5.99M | 0.00% | −126−0.3% | Reduced |
| New York State Teachers Retirement System | 49,550 | $6.07M | 0.01% | +2,126+4.5% | Added |
| Granahan Investment Management Inc | 49,809 | $6.11M | 0.22% | +22,418+81.8% | Added |
| Castleark Management LLC | 50,570 | $6.20M | 0.17% | +50,570 | New |
| Vanguard Asset Management, Ltd | 51,639 | $6.33M | 0.00% | +5,253+11.3% | Added |
| Bessemer Group Inc | 52,074 | $6.38M | 0.01% | −2,104−3.9% | Reduced |
| KVP Capital Advisors, LP | 53,000 | $6.50M | 4.77% | 00.0% | Unchanged |
| First Trust Advisors LP | 54,865 | $6.73M | 0.00% | −32,993−37.6% | Reduced |
| Bellevue Group AG | 55,682 | $6.83M | 0.14% | +41,235+285.4% | Added |
| Creative Planning | 56,185 | $6.89M | 0.00% | +8,214+17.1% | Added |
| Great Lakes Advisors, LLC | 56,904 | $6.98M | 0.05% | −14,139−19.9% | Reduced |
| Susquehanna International Group, LLP | 57,062 | $6.99M | 0.01% | −110,514−65.9% | Reduced |
| Eversept Partners, LP | 58,504 | $7.17M | 0.39% | +58,504 | New |
| California State Teachers Retirement System | 58,961 | $7.23M | 0.01% | +284+0.5% | Added |
| Moody Aldrich Partners LLC | 59,601 | $7.31M | 1.31% | +5,708+10.6% | Added |
| Atika Capital Management LLC | 62,100 | $7.61M | 0.76% | 00.0% | Unchanged |
| Knott David M Jr | 63,000 | $7.72M | 4.08% | 00.0% | Unchanged |
| Schroder Investment Management Group | 64,991 | $7.90M | 0.01% | −35,175−35.1% | Reduced |
| Nordea Investment Management AB | 64,964 | $7.94M | 0.01% | +13,143+25.4% | Added |
| Alliancebernstein L.P. | 79,563 | $8.39M | 0.00% | +5,773+7.8% | Added |
| Wells Fargo & Company | 71,944 | $8.82M | 0.00% | +41,872+139.2% | Added |
| Axiom Investors LLC | 81,683 | $10.0M | 0.09% | −3,792−4.4% | Reduced |
| Victory Capital Management Inc | 83,883 | $10.3M | 0.01% | +339+0.4% | Added |
| Prudential Financial Inc | 85,180 | $10.4M | 0.01% | −10,055−10.6% | Reduced |
| Algert Global LLC | 87,698 | $10.8M | 0.13% | +9,228+11.8% | Added |
| SEI Investments Co | 92,749 | $11.4M | 0.01% | +9,552+11.5% | Added |
| Assetmark, Inc | 98,687 | $12.1M | 0.02% | +52,245+112.5% | Added |
| Opaleye Management Inc. | 100,000 | $12.3M | 1.11% | 00.0% | Unchanged |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 102,002 | $12.5M | 0.02% | −3,512−3.3% | Reduced |
| Swiss National Bank | 102,400 | $12.6M | 0.01% | +3,500+3.5% | Added |
| Catalio Capital Management, LP | 106,799 | $13.1M | 2.46% | +106,799 | New |
| UBS Asset Management Americas Inc | 107,094 | $13.1M | 0.00% | −343−0.3% | Reduced |
| Manufacturers Life Insurance Company, The | 108,555 | $13.3M | 0.01% | −19,263−15.1% | Reduced |
| Marshall Wace, LLP | 109,017 | $13.4M | 0.01% | −519,058−82.6% | Reduced |
| Russell Investments Group, Ltd. | 115,425 | $14.1M | 0.01% | +75,049+185.9% | Added |
| Legal & General Group Plc | 132,351 | $16.2M | 0.00% | −3,016−2.2% | Reduced |
| Kennedy Capital Management, Inc. | 134,019 | $16.4M | 0.29% | −3,080−2.2% | Reduced |
| TD Asset Management Inc | 134,950 | $16.5M | 0.01% | −48,750−26.5% | Reduced |
| Nomura Asset Management International Inc. | 141,081 | $17.3M | 0.03% | +141,081 | New |
| Rhumbline Advisers | 141,279 | $17.3M | 0.01% | −16,134−10.2% | Reduced |
| Deutsche Bank AG | 141,838 | $17.4M | 0.01% | +16,387+13.1% | Added |
| Ameriprise Financial Inc | 143,810 | $17.6M | 0.00% | −1,880−1.3% | Reduced |
| Nan Fung Trinity (HK) Ltd | 160,670 | $19.7M | 1.94% | 00.0% | Unchanged |
| Raymond James Financial Inc | 168,270 | $20.6M | 0.01% | −9,091−5.1% | Reduced |
| Boxer Capital Management, LLC | 170,000 | $20.8M | 1.57% | 00.0% | Unchanged |
| Fisher Asset Management, LLC | 170,524 | $20.9M | 0.01% | −3,447−2.0% | Reduced |
| Affinity Asset Advisors, LLC | 172,125 | $21.1M | 1.03% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 178,152 | $21.8M | 0.00% | −329,951−64.9% | Reduced |
| JPMorgan Chase & Co | 183,098 | $22.6M | 0.00% | +10,108+5.8% | Added |
| Citigroup Inc | 198,668 | $24.4M | 0.01% | +39,957+25.2% | Added |
| Public Sector Pension Investment Board | 207,688 | $25.5M | 0.07% | −2,592−1.2% | Reduced |