Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 322
- +10 vs. Q4 2025
- Shares held
- 78.9M
- +13.3M (+20.3%) vs. Q4 2025
- Total value
- $8.31B
- +$2.61B (+45.7%) vs. Q4 2025
- New holders
- 60
- 111 more added
- Sold out
- 50
- 104 more reduced
7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Abound Wealth Management | 2 | $211 | 0.00% | −2−50.0% | Reduced |
| Root Financial Partners, LLC | 3 | $316 | 0.00% | 00.0% | Unchanged |
| Prestige Wealth Management Group LLC | 3 | $317 | 0.00% | +3 | New |
| DecisionPoint Financial, LLC | 4 | $422 | 0.00% | 00.0% | Unchanged |
| Kilter Group LLC | 4 | $422 | 0.00% | 00.0% | Unchanged |
| Hughes Financial Services, LLC | 6 | $632 | 0.00% | +4+200.0% | Added |
| Trust Co | 7 | $738 | 0.00% | 00.0% | Unchanged |
| Rossby Financial, LCC | 9 | $933 | 0.00% | +9 | New |
| Gilpin Wealth Management, LLC | 9 | $949 | 0.00% | +4+80.0% | Added |
| Ankerstar Wealth, LLC | 12 | $1.26K | 0.00% | 00.0% | Unchanged |
| MAI Capital Management | 14 | $1.48K | 0.00% | −83−85.6% | Reduced |
| Private Wealth Management Group, LLC | 16 | $1.69K | 0.00% | +16 | New |
| Triumph Capital Management | 18 | $1.90K | 0.00% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 18 | $1.90K | 0.00% | +18 | New |
| Harbour Investments, Inc. | 19 | $2.04K | 0.00% | +17+850.0% | Added |
| Pension & Wealth Management Advisors, Inc. | 20 | $2.11K | 0.00% | +20 | New |
| UMA Financial Services, Inc. | 21 | $2.21K | 0.00% | 00.0% | Unchanged |
| Whipplewood Advisors, LLC | 22 | $2.32K | 0.00% | +22 | New |
| Zions Bancorporation, National Association | 23 | $2.42K | 0.00% | +23 | New |
| Picton Mahoney Asset Management | 25 | $2.63K | 0.00% | 00.0% | Unchanged |
| Golden State Equity Partners | 27 | $2.85K | 0.00% | +27 | New |
| Versant Capital Management, Inc | 27 | $2.85K | 0.00% | 00.0% | Unchanged |
| Marquette Asset Management, LLC | 28 | $2.95K | 0.00% | 00.0% | Unchanged |
| Torren Management, LLC | 30 | $3.16K | 0.00% | −9−23.1% | Reduced |
| Huntington National Bank | 35 | $3.69K | 0.00% | 00.0% | Unchanged |
| Farmers & Merchants Investments Inc | 35 | $3.69K | 0.00% | 00.0% | Unchanged |
| Wolff Wiese Magana LLC | 35 | $3.69K | 0.00% | 00.0% | Unchanged |
| MCF Advisors LLC | 40 | $4.22K | 0.00% | +40 | New |
| Hollencrest Capital Management | 45 | $4.74K | 0.00% | +45 | New |
| Sankala Group LLC | 60 | $6.07K | 0.00% | 00.0% | Unchanged |
| Raffa Wealth Management, LLC | 60 | $6.32K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 70 | $7.38K | 0.00% | 00.0% | Unchanged |
| Parkside Financial Bank & Trust | 76 | $8.01K | 0.00% | −8−9.5% | Reduced |
| Annis Gardner Whiting Capital Advisors, LLC | 76 | $8.01K | 0.00% | 00.0% | Unchanged |
| Brown Brothers Harriman & Co | 81 | $8.54K | 0.00% | 00.0% | Unchanged |
| Bell Investment Advisors, Inc | 81 | $8.54K | 0.00% | 00.0% | Unchanged |
| Bare Financial Services, Inc | 95 | $10.0K | 0.00% | −15−13.6% | Reduced |
| WPG Advisers, LLC | 97 | $10.2K | 0.01% | +1+1.0% | Added |
| Rothschild Investment LLC | 107 | $11.3K | 0.00% | +21+24.4% | Added |
| Cedar Mountain Advisors, LLC | 113 | $11.9K | 0.00% | +113 | New |
| Parallel Advisors, LLC | 123 | $13.0K | 0.00% | +14+12.8% | Added |
| Massmutual Trust Co FSB | 125 | $13.2K | 0.00% | +6+5.0% | Added |
| Sound Income Strategies, LLC | 156 | $16.2K | 0.00% | −128−45.1% | Reduced |
| E Fund Management (Hong Kong) Co., Ltd. | 156 | $16.4K | 0.01% | +156 | New |
| Twin Peaks Wealth Advisors, LLC | 173 | $18.2K | 0.00% | +173 | New |
| Clearstead Advisors, LLC | 200 | $21.1K | 0.00% | −22−9.9% | Reduced |
| Keating Financial Advisory Services, Inc. | 224 | $23.6K | 0.00% | +222+11,100.0% | Added |
| Signaturefd, LLC | 288 | $30.4K | 0.00% | +125+76.7% | Added |
| Allworth Financial LP | 313 | $33.0K | 0.00% | +58+22.7% | Added |
| Farther Finance Advisors, LLC | 333 | $34.5K | 0.00% | +36+12.1% | Added |
| Ameritas Advisory Services, LLC | 334 | $35.2K | 0.00% | +334 | New |
| Toronto Dominion Bank | 349 | $36.8K | 0.00% | +349 | New |
| Umb Bank N A | 353 | $37.2K | 0.00% | +20+6.0% | Added |
| Sterling Capital Management LLC | 377 | $39.7K | 0.00% | −1−0.3% | Reduced |
| Kemnay Advisory Services Inc. | 521 | $54.9K | 0.01% | +340+187.8% | Added |
| Salomon & Ludwin, LLC | 595 | $61.7K | 0.01% | +159+36.5% | Added |
| CFG Wealth Management Services, Inc. | 611 | $64.4K | 0.06% | +9+1.5% | Added |
| CWM, LLC | 737 | $77.7K | 0.00% | +181+32.6% | Added |
| Larson Financial Group LLC | 819 | $86.3K | 0.00% | +648+378.9% | Added |
| Smartleaf Asset Management LLC | 890 | $88.9K | 0.00% | −837−48.5% | Reduced |
| Hantz Financial Services, Inc. | 857 | $90.0K | 0.00% | −94−9.9% | Reduced |
| Covestor Ltd | 875 | $92.0K | 0.06% | −562−39.1% | Reduced |
| EverSource Wealth Advisors, LLC | 911 | $96.0K | 0.00% | +352+63.0% | Added |
| Canton Hathaway, LLC | 1,000 | $105.4K | 0.02% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 1,001 | $105.5K | 0.00% | +1,001 | New |
| Truvestments Capital LLC | 1,161 | $122.4K | 0.02% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 1,197 | $126.2K | 0.00% | −3,004−71.5% | Reduced |
| GF Fund Management Co. Ltd. | 1,404 | $148.0K | 0.00% | +177+14.4% | Added |
| Quadrant Capital Group LLC | 1,429 | $150.6K | 0.00% | −38−2.6% | Reduced |
| KBC Group NV | 1,574 | $166.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 1,599 | $169.0K | 0.00% | −1,584−49.8% | Reduced |
| Oppenheimer & Co Inc | 1,900 | $200.3K | 0.00% | +1,900 | New |
| Captrust Financial Advisors | 1,902 | $200.5K | 0.00% | −830−30.4% | Reduced |
| HSBC Holdings PLC | 1,907 | $201.0K | 0.00% | +1,907 | New |
| Shelton Capital Management | 1,908 | $201.1K | 0.00% | +1,908 | New |
| Axiom Investment Management LLC | 2,000 | $210.8K | 0.16% | +2,000 | New |
| Prelude Capital Management, LLC | 2,012 | $212.1K | 0.02% | +2,012 | New |
| Concurrent Investment Advisors, LLC | 2,060 | $217.1K | 0.00% | +2,060 | New |
| TFB Advisors LLC | 2,191 | $230.9K | 0.12% | +2,191 | New |
| RSM US Wealth Management LLC | 2,234 | $235.5K | 0.00% | +2,234 | New |
| DnB Asset Management AS | 2,244 | $236.5K | 0.00% | +2,244 | New |
| Empowered Funds, LLC | 2,321 | $244.6K | 0.00% | +2,321 | New |
| GTS Securities LLC | 2,416 | $254.6K | 0.01% | +2,416 | New |
| O'Shaughnessy Asset Management, LLC | 2,440 | $257.2K | 0.00% | −1,929−44.2% | Reduced |
| Vise Technologies, Inc. | 2,996 | $261.7K | 0.01% | 00.0% | Unchanged |
| NBC Securities, Inc. | 2,547 | $268.5K | 0.02% | −430−14.4% | Reduced |
| Eventide Asset Management, LLC | 2,795 | $279.2K | 0.00% | +2,795 | New |
| CIBC Asset Management Inc | 2,667 | $281.1K | 0.00% | 00.0% | Unchanged |
| New Age Alpha Advisors, LLC | 2,706 | $285.2K | 0.01% | −78−2.8% | Reduced |
| Jones Financial Companies LLLP | 2,923 | $289.3K | 0.00% | +2,877+6,254.3% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 2,760 | $290.9K | 0.00% | +200+7.8% | Added |
| Mariner, LLC | 2,775 | $292.4K | 0.00% | −4,845−63.6% | Reduced |
| LPL Financial LLC | 2,793 | $294.4K | 0.00% | −472−14.5% | Reduced |
| Norden Group LLC | 2,810 | $296.2K | 0.03% | +2,810 | New |
| Evergreen Capital Management LLC | 2,820 | $297.2K | 0.01% | +8+0.3% | Added |
| Virtus Investment Advisers, Inc. | 2,860 | $301.4K | 0.08% | +70+2.5% | Added |
| AE Wealth Management LLC | 2,888 | $304.4K | 0.00% | +2,888 | New |
| GAMMA Investing LLC | 2,901 | $305.8K | 0.01% | +229+8.6% | Added |
| Headlands Technologies LLC | 2,957 | $311.7K | 0.04% | −14,122−82.7% | Reduced |
| CIBC Bancorp USA Inc. | 2,968 | $312.8K | 0.00% | +2,968 | New |