Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2025
Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 275
- +38 vs. Q4 2024
- Shares held
- 65.3M
- +2.28M (+3.6%) vs. Q4 2024
- Total value
- $3.15B
- +$716.0M (+29.4%) vs. Q4 2024
- New holders
- 72
- 86 more added
- Sold out
- 34
- 90 more reduced
4 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Springhill Fund Asset Management (HK) Co Ltd | 12,859 | $621.9K | 2.98% | +12,859 | New |
| Police & Firemen's Retirement System of New Jersey | 12,928 | $625.2K | 0.01% | +487+3.9% | Added |
| CIBC World Markets Corp | 13,178 | $637.3K | 0.01% | +7,710+141.0% | Added |
| Aviva PLC | 13,200 | $638.4K | 0.00% | −1,427−9.8% | Reduced |
| UBS Oconnor LLC | 13,340 | $645.1K | 0.02% | +13,340 | New |
| Erste Asset Management GmbH | 13,500 | $659.9K | 0.01% | 00.0% | Unchanged |
| Oregon Public Employees Retirement Fund | 13,700 | $662.5K | 0.01% | −300−2.1% | Reduced |
| BNP Paribas Arbitrage, SA | 14,169 | $685.2K | 0.00% | −5,296−27.2% | Reduced |
| XTX Topco Ltd | 14,257 | $689.5K | 0.04% | +7,513+111.4% | Added |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 14,262 | $689.7K | 0.00% | +1,539+12.1% | Added |
| Handelsbanken Fonder AB | 14,400 | $696.0K | 0.00% | −3,200−18.2% | Reduced |
| Aquatic Capital Management LLC | 15,107 | $730.6K | 0.02% | +15,107 | New |
| Engineers Gate Manager LP | 15,327 | $741.2K | 0.01% | +15,327 | New |
| Moran Wealth Management, LLC | 15,895 | $768.7K | 0.03% | −66−0.4% | Reduced |
| Harvest Investment Services, LLC | 15,911 | $769.5K | 0.22% | +15,911 | New |
| DekaBank Deutsche Girozentrale | 15,800 | $771.0K | 0.00% | 00.0% | Unchanged |
| Brevan Howard Capital Management LP | 16,114 | $779.3K | 0.02% | +16,114 | New |
| State Board of Administration of Florida Retirement System | 16,303 | $788.4K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 16,631 | $804.3K | 0.00% | −1,352−7.5% | Reduced |
| Envestnet Asset Management Inc | 16,679 | $806.6K | 0.00% | +7,698+85.7% | Added |
| ProShare Advisors LLC | 16,758 | $810.4K | 0.00% | −3,699−18.1% | Reduced |
| Amalgamated Bank | 16,938 | $819.0K | 0.01% | −467−2.7% | Reduced |
| Creative Planning | 17,333 | $838.2K | 0.00% | +10,885+168.8% | Added |
| Maryland State Retirement & Pension System | 17,398 | $841.4K | 0.02% | −2,772−13.7% | Reduced |
| Virginia Retirement Systems Et Al | 17,600 | $851.1K | 0.01% | +17,600 | New |
| Bellevue Group AG | 17,622 | $852.2K | 0.02% | −6,096−25.7% | Reduced |
| Scientech Research LLC | 18,271 | $883.6K | 0.23% | +6,217+51.6% | Added |
| Jennison Associates LLC | 18,317 | $885.8K | 0.00% | +18,317 | New |
| Algert Global LLC | 18,665 | $902.6K | 0.02% | +945+5.3% | Added |
| China Universal Asset Management Co., Ltd. | 18,772 | $907.8K | 0.08% | +6,135+48.5% | Added |
| Guggenheim Capital LLC | 18,905 | $914.2K | 0.01% | −173−0.9% | Reduced |
| STRS Ohio | 19,000 | $918.8K | 0.00% | −4,500−19.1% | Reduced |
| Campbell & CO Investment Adviser LLC | 19,015 | $919.6K | 0.07% | +19,015 | New |
| Toroso Investments, LLC | 19,410 | $938.7K | 0.01% | −1,602−7.6% | Reduced |
| Illinois Municipal Retirement Fund | 19,509 | $943.5K | 0.01% | −14,000−41.8% | Reduced |
| New York State Common Retirement Fund | 19,582 | $947.0K | 0.00% | +1,700+9.5% | Added |
| Coppell Advisory Solutions LLC | 20,765 | $947.3K | 0.14% | +20,765 | New |
| Verition Fund Management LLC | 19,847 | $959.8K | 0.01% | +19,847 | New |
| Y-Intercept (Hong Kong) Ltd | 20,169 | $975.4K | 0.07% | +20,169 | New |
| Teachers Retirement System of the State of Kentucky | 20,200 | $977.0K | 0.01% | 00.0% | Unchanged |
| Comerica Bank | 20,241 | $978.9K | 0.00% | −317−1.5% | Reduced |
| Glenmede Trust Co NA | 20,666 | $999.4K | 0.01% | +11,713+130.8% | Added |
| Winton Group Ltd | 20,795 | $1.01M | 0.06% | −5,973−22.3% | Reduced |
| Janus Henderson Group PLC | 21,454 | $1.05M | 0.00% | 00.0% | Unchanged |
| CWM Advisors, LLC | 21,834 | $1.06M | 0.13% | +11,279+106.9% | Added |
| Yousif Capital Management, LLC | 22,337 | $1.08M | 0.01% | −581−2.5% | Reduced |
| Mackenzie Financial Corp | 22,698 | $1.10M | 0.00% | +1,349+6.3% | Added |
| Gotham Asset Management, LLC | 23,072 | $1.12M | 0.01% | +23,072 | New |
| Jain Global LLC | 24,867 | $1.20M | 0.02% | +24,867 | New |
| Simplex Trading, LLC | 25,934 | $1.25M | 0.04% | +20,447+372.6% | Added |
| Quadrature Capital Ltd | 26,061 | $1.26M | 0.03% | +26,061 | New |
| Hennion & Walsh Asset Management, Inc. | 26,066 | $1.26M | 0.06% | −6,008−18.7% | Reduced |
| State of Tennessee, Treasury Department | 26,485 | $1.28M | 0.00% | −591−2.2% | Reduced |
| Ensign Peak Advisors, Inc | 27,036 | $1.31M | 0.00% | 00.0% | Unchanged |
| Exchange Traded Concepts, LLC | 27,392 | $1.32M | 0.02% | +26,367+2,572.4% | Added |
| Louisiana State Employees Retirement System | 28,100 | $1.36M | 0.03% | −700−2.4% | Reduced |
| Intech Investment Management LLC | 30,982 | $1.50M | 0.02% | −498−1.6% | Reduced |
| Corebridge Financial, Inc. | 31,020 | $1.50M | 0.01% | −135−0.4% | Reduced |
| Massachusetts Financial Services Co | 31,726 | $1.53M | 0.00% | −723−2.2% | Reduced |
| State of Alaska, Department of Revenue | 33,023 | $1.60M | 0.02% | −848−2.5% | Reduced |
| MetLife Investment Management | 34,790 | $1.68M | 0.01% | −1,008−2.8% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 37,403 | $1.81M | 0.00% | +348+0.9% | Added |
| SEI Investments Co | 37,528 | $1.81M | 0.00% | +12,960+52.8% | Added |
| Wells Fargo & Company | 39,809 | $1.93M | 0.00% | +1,013+2.6% | Added |
| Axiom Investors LLC | 39,969 | $1.93M | 0.02% | +39,969 | New |
| AQR Capital Management LLC | 40,087 | $1.94M | 0.00% | −110,010−73.3% | Reduced |
| California State Teachers Retirement System | 41,856 | $2.02M | 0.00% | −493−1.2% | Reduced |
| Tudor Investment Corp Et Al | 42,583 | $2.06M | 0.02% | +42,583 | New |
| Thrivent Financial for Lutherans | 43,776 | $2.12M | 0.00% | −2,290−5.0% | Reduced |
| Rafferty Asset Management, LLC | 44,257 | $2.14M | 0.01% | −51,210−53.6% | Reduced |
| Assenagon Asset Management S.A. | 44,872 | $2.17M | 0.00% | −7,367−14.1% | Reduced |
| New York State Teachers Retirement System | 46,855 | $2.27M | 0.01% | +22,263+90.5% | Added |
| D. E. Shaw & Co., Inc. | 47,361 | $2.29M | 0.00% | +41,657+730.3% | Added |
| Birchview Capital, LP | 48,002 | $2.32M | 2.02% | +20.0% | Added |
| StemPoint Capital LP | 49,241 | $2.38M | 0.76% | −92,473−65.3% | Reduced |
| Great West Life Assurance Co | 50,955 | $2.46M | 0.00% | −5,581−9.9% | Reduced |
| Hussman Strategic Advisors, Inc. | 52,500 | $2.54M | 0.62% | −52,500−50.0% | Reduced |
| Alps Advisors Inc | 52,974 | $2.56M | 0.01% | −2,967−5.3% | Reduced |
| State of New Jersey Common Pension Fund D | 53,736 | $2.60M | 0.01% | +53,736 | New |
| State of Wisconsin Investment Board | 53,740 | $2.60M | 0.01% | +2,958+5.8% | Added |
| Silvercrest Asset Management Group LLC | 54,723 | $2.65M | 0.02% | −29,703−35.2% | Reduced |
| Jump Financial, LLC | 56,780 | $2.75M | 0.04% | +56,780 | New |
| Prudential Financial Inc | 58,358 | $2.82M | 0.00% | −1,640−2.7% | Reduced |
| BCJ Capital Management, LLC | 58,413 | $2.82M | 0.20% | +58,413 | New |
| Voya Investment Management LLC | 59,678 | $2.89M | 0.00% | −22,949−27.8% | Reduced |
| J. Goldman & Co LP | 65,244 | $3.16M | 0.11% | +65,244 | New |
| Deutsche Bank AG | 65,695 | $3.18M | 0.00% | −72,237−52.4% | Reduced |
| Alliancebernstein L.P. | 67,900 | $3.28M | 0.00% | −325−0.5% | Reduced |
| EAM Investors, LLC | 69,181 | $3.35M | 0.58% | +69,181 | New |
| HRT Financial LP | 69,242 | $3.35M | 0.02% | +61,217+762.8% | Added |
| EAM Global Investors LLC | 69,750 | $3.37M | 0.92% | +69,750 | New |
| EFG Asset Management (North America) Corp. | 71,134 | $3.44M | 0.57% | +71,134 | New |
| Knott David M Jr | 76,000 | $3.68M | 1.73% | +23,632+45.1% | Added |
| HighVista Strategies LLC | 78,452 | $3.79M | 1.46% | +15,934+25.5% | Added |
| Northwestern Mutual Wealth Management Co | 78,894 | $3.82M | 0.00% | 00.0% | Unchanged |
| Franklin Resources Inc | 79,044 | $3.82M | 0.00% | −9,826−11.1% | Reduced |
| First Trust Advisors LP | 81,686 | $3.95M | 0.00% | −59,265−42.0% | Reduced |
| Aquilo Capital Management, LLC | 81,692 | $3.95M | 10.65% | +5,100+6.7% | Added |
| Swiss National Bank | 86,900 | $4.20M | 0.00% | 00.0% | Unchanged |
| Lazard Asset Management LLC | 96,420 | $4.66M | 0.01% | +96,420 | New |