Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2024
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 241
- +4 vs. Q3 2024
- Shares held
- 63.3M
- +1.83M (+3.0%) vs. Q3 2024
- Total value
- $2.44B
- −$321.9M (−11.6%) vs. Q3 2024
- New holders
- 45
- 91 more added
- Sold out
- 41
- 76 more reduced
3 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| UBS Asset Management Americas Inc | 287,911 | $11.1M | 0.00% | −80,221−21.8% | Reduced |
| Artia Global Partners LP | 293,851 | $11.3M | 4.57% | +169,411+136.1% | Added |
| Pictet Asset Management Holding SA | 296,511 | $11.4M | 0.01% | +289,213+3,962.9% | Added |
| Raymond James Financial Inc | 303,313 | $11.7M | 0.00% | +303,313 | New |
| Skandinaviska Enskilda Banken AB (publ) | 310,650 | $12.0M | 0.05% | +80,536+35.0% | Added |
| Qube Research & Technologies Ltd | 312,319 | $12.1M | 0.02% | −10,670−3.3% | Reduced |
| Kennedy Capital Management, Inc. | 321,526 | $12.4M | 0.28% | +54,493+20.4% | Added |
| Principal Financial Group Inc | 337,809 | $13.0M | 0.01% | +16,977+5.3% | Added |
| Driehaus Capital Management LLC | 339,698 | $13.1M | 0.11% | −105,654−23.7% | Reduced |
| Toronto Dominion Bank | 340,974 | $13.2M | 0.03% | +340,974 | New |
| Polar Capital Holdings Plc | 350,000 | $13.5M | 0.08% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 390,788 | $15.1M | 0.00% | +34,455+9.7% | Added |
| Kynam Capital Management, LP | 390,792 | $15.1M | 1.00% | −65,577−14.4% | Reduced |
| Mangrove Partners | 395,383 | $15.3M | 1.82% | −43,931−10.0% | Reduced |
| 683 Capital Management, LLC | 410,000 | $15.8M | 1.56% | −10,000−2.4% | Reduced |
| Colony Group, LLC | 425,557 | $16.4M | 0.04% | −1,104−0.3% | Reduced |
| FMR LLC | 442,516 | $17.1M | 0.00% | −11,680−2.6% | Reduced |
| Morgan Stanley | 540,315 | $20.9M | 0.00% | −88,308−14.0% | Reduced |
| JPMorgan Chase & Co | 576,977 | $22.3M | 0.00% | +73,992+14.7% | Added |
| Charles Schwab Investment Management Inc | 578,409 | $22.3M | 0.00% | +12,906+2.3% | Added |
| Woodline Partners LP | 582,327 | $22.5M | 0.15% | +115,809+24.8% | Added |
| Northern Trust Corp | 628,580 | $24.3M | 0.00% | +48,491+8.4% | Added |
| Eversept Partners, LP | 678,787 | $26.2M | 2.70% | +233,583+52.5% | Added |
| Invesco Ltd. | 738,952 | $28.5M | 0.01% | +85,800+13.1% | Added |
| Goldman Sachs Group Inc | 758,690 | $29.3M | 0.01% | −63,166−7.7% | Reduced |
| American Century Companies Inc | 928,286 | $35.8M | 0.02% | +353,511+61.5% | Added |
| Wellington Management Group LLP | 940,077 | $36.3M | 0.01% | +909,998+3,025.4% | Added |
| Deep Track Capital, LP | 1,000,000 | $38.6M | 1.45% | +1,000,000 | New |
| ADAR1 Capital Management, LLC | 1,020,333 | $39.4M | 8.12% | +39,038+4.0% | Added |
| Perceptive Advisors LLC | 1,271,662 | $49.1M | 1.37% | −102,901−7.5% | Reduced |
| Geode Capital Management, LLC | 1,377,063 | $53.2M | 0.00% | +2,366+0.2% | Added |
| Price T Rowe Associates Inc | 1,392,652 | $53.8M | 0.01% | +83,185+6.4% | Added |
| Jefferies Financial Group Inc. | 1,489,495 | $57.5M | 0.64% | −325,201−17.9% | Reduced |
| Pacer Advisors, Inc. | 1,876,466 | $72.4M | 0.16% | +142,376+8.2% | Added |
| BVF Inc | 1,900,015 | $73.3M | 2.49% | +49,848+2.7% | Added |
| Johnson & Johnson | 2,449,183 | $94.5M | 24.48% | 00.0% | Unchanged |
| State Street Corp | 3,331,061 | $128.6M | 0.01% | +147,519+4.6% | Added |
| Vanguard Group Inc | 4,220,037 | $162.9M | 0.00% | +3,956+0.1% | Added |
| RTW Investments, LP | 5,498,545 | $212.2M | 3.21% | +72,433+1.3% | Added |
| Farallon Capital Management, L.L.C. | 5,930,006 | $228.9M | 1.21% | +69,000+1.2% | Added |
| BlackRock, Inc. | 9,884,617 | $381.5M | 0.01% | −339,678−3.3% | Reduced |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −1,200,891−100.0% | Sold out |
| Cowen and Company, LLC | 0 | $0 | 0.00% | −340,974−100.0% | Sold out |
| Checkpoint Capital L.P. | 0 | $0 | 0.00% | −240,000−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −214,872−100.0% | Sold out |
| Candriam Luxembourg S.C.A. | 0 | $0 | 0.00% | −162,492−100.0% | Sold out |
| Silverarc Capital Management, LLC | 0 | $0 | 0.00% | −146,657−100.0% | Sold out |
| Segall Bryant & Hamill, LLC | 0 | $0 | 0.00% | −120,301−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −105,335−100.0% | Sold out |
| Weiss Asset Management LP | 0 | $0 | 0.00% | −62,463−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −61,026−100.0% | Sold out |
| Point72 Europe (London) LLP | 0 | $0 | 0.00% | −45,317−100.0% | Sold out |
| Jackson Creek Investment Advisors LLC | 0 | $0 | 0.00% | −44,685−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −25,740−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −25,095−100.0% | Sold out |
| Financial Enhancement Group LLC | 0 | $0 | 0.00% | −41,818−100.0% | Sold out |
| Janney Montgomery Scott LLC | 0 | $0 | 0.00% | −19,249−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −18,566−100.0% | Sold out |
| Sherbrooke Park Advisers LLC | 0 | $0 | 0.00% | −13,993−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −13,858−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −12,100−100.0% | Sold out |
| HighTower Advisors, LLC | 0 | $0 | 0.00% | −10,887−100.0% | Sold out |
| MYDA Advisors LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Teza Capital Management LLC | 0 | $0 | 0.00% | −9,463−100.0% | Sold out |
| Nomura Holdings Inc | 0 | $0 | 0.00% | −8,159−100.0% | Sold out |
| Everence Capital Management Inc | 0 | $0 | 0.00% | −7,050−100.0% | Sold out |
| Entropy Technologies, LP | 0 | $0 | 0.00% | −6,929−100.0% | Sold out |
| Brinker Capital Investments, LLC | 0 | $0 | 0.00% | −6,114−100.0% | Sold out |
| Orion Portfolio Solutions, LLC | 0 | $0 | 0.00% | −6,114−100.0% | Sold out |
| CenterBook Partners LP | 0 | $0 | 0.00% | −5,976−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −5,251−100.0% | Sold out |
| Palumbo Wealth Management LLC | 0 | $0 | 0.00% | −5,211−100.0% | Sold out |
| AXA S.A. | 0 | $0 | 0.00% | −4,888−100.0% | Sold out |
| O'Shaughnessy Asset Management, LLC | 0 | $0 | 0.00% | −4,551−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | $0 | 0.00% | −2,699−100.0% | Sold out |
| Lazard Asset Management LLC | 0 | $0 | 0.00% | −2,697−100.0% | Sold out |
| Globeflex Capital L P | 0 | $0 | 0.00% | −2,627−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −140−100.0% | Sold out |
| True Wealth Design, LLC | 0 | $0 | 0.00% | −96−100.0% | Sold out |
| Capital Performance Advisors LLP | 0 | $0 | 0.00% | −79−100.0% | Sold out |
| Signaturefd, LLC | 0 | $0 | 0.00% | −20−100.0% | Sold out |
| Mendota Financial Group, LLC | 0 | $0 | 0.00% | −6−100.0% | Sold out |
| Eagle Asset Management Inc | – | – | – | – | Not filed |
| Raymond James & Associates | – | – | – | – | Not filed |
| PEAK6 Investments LLC | – | – | – | – | Not filed |