Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2024
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 241
- +4 vs. Q3 2024
- Shares held
- 63.3M
- +1.83M (+3.0%) vs. Q3 2024
- Total value
- $2.44B
- −$321.9M (−11.6%) vs. Q3 2024
- New holders
- 45
- 91 more added
- Sold out
- 41
- 76 more reduced
3 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Moran Wealth Management, LLC | 15,961 | $616.1K | 0.02% | +931+6.2% | Added |
| State Board of Administration of Florida Retirement System | 16,303 | $629.3K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 17,405 | $672.0K | 0.01% | +81+0.5% | Added |
| Handelsbanken Fonder AB | 17,600 | $679.0K | 0.00% | +17,600 | New |
| Algert Global LLC | 17,720 | $684.0K | 0.02% | −97,959−84.7% | Reduced |
| New York State Common Retirement Fund | 17,882 | $690.2K | 0.00% | −2,300−11.4% | Reduced |
| Mariner, LLC | 17,983 | $694.1K | 0.00% | +2,004+12.5% | Added |
| Guggenheim Capital LLC | 19,078 | $736.4K | 0.01% | +11,180+141.6% | Added |
| BNP Paribas Arbitrage, SA | 19,465 | $751.3K | 0.00% | −829−4.1% | Reduced |
| Marshall Wace, LLP | 19,716 | $761.0K | 0.00% | −295,657−93.7% | Reduced |
| Braidwell LP | 20,109 | $776.2K | 0.02% | +20,109 | New |
| Maryland State Retirement & Pension System | 20,170 | $778.6K | 0.02% | +278+1.4% | Added |
| Boothbay Fund Management, LLC | 20,188 | $779.3K | 0.02% | +20,188 | New |
| Teachers Retirement System of the State of Kentucky | 20,200 | $780.0K | 0.01% | 00.0% | Unchanged |
| ProShare Advisors LLC | 20,457 | $789.6K | 0.00% | +4,776+30.5% | Added |
| Comerica Bank | 20,558 | $793.5K | 0.00% | −346−1.7% | Reduced |
| Profund Advisors LLC | 20,649 | $797.1K | 0.03% | +566+2.8% | Added |
| Toroso Investments, LLC | 21,012 | $811.1K | 0.01% | −1,050−4.8% | Reduced |
| Mackenzie Financial Corp | 21,349 | $824.1K | 0.00% | +13,575+174.6% | Added |
| Janus Henderson Group PLC | 21,454 | $827.8K | 0.00% | 00.0% | Unchanged |
| Sierra Summit Advisors LLC | 22,282 | $860.1K | 0.17% | +1,115+5.3% | Added |
| Yousif Capital Management, LLC | 22,918 | $884.6K | 0.01% | −322−1.4% | Reduced |
| STRS Ohio | 23,500 | $907.1K | 0.00% | +2,000+9.3% | Added |
| Summit Global Investments | 23,557 | $909.0K | 0.06% | +23,557 | New |
| Bellevue Group AG | 23,718 | $915.5K | 0.02% | +11,372+92.1% | Added |
| SEI Investments Co | 24,568 | $948.3K | 0.00% | −10,510−30.0% | Reduced |
| New York State Teachers Retirement System | 24,592 | $949.0K | 0.00% | 00.0% | Unchanged |
| Winton Group Ltd | 26,768 | $1.03M | 0.07% | +785+3.0% | Added |
| Ensign Peak Advisors, Inc | 27,036 | $1.04M | 0.00% | 00.0% | Unchanged |
| State of Tennessee, Treasury Department | 27,076 | $1.05M | 0.00% | −667−2.4% | Reduced |
| Capital Fund Management S.A. | 28,058 | $1.08M | 0.01% | +28,058 | New |
| Louisiana State Employees Retirement System | 28,800 | $1.11M | 0.02% | +300+1.1% | Added |
| ExodusPoint Capital Management, LP | 29,870 | $1.15M | 0.01% | +29,870 | New |
| Corebridge Financial, Inc. | 31,155 | $1.20M | 0.01% | −2,407−7.2% | Reduced |
| Cavalier Investments, LLC | 31,252 | $1.21M | 0.40% | +1,296+4.3% | Added |
| Los Angeles Capital Management LLC | 31,366 | $1.21M | 0.00% | +8,920+39.7% | Added |
| Intech Investment Management LLC | 31,480 | $1.22M | 0.01% | +12,352+64.6% | Added |
| Hennion & Walsh Asset Management, Inc. | 32,074 | $1.24M | 0.06% | −5,339−14.3% | Reduced |
| Massachusetts Financial Services Co | 32,449 | $1.25M | 0.00% | +32,449 | New |
| Illinois Municipal Retirement Fund | 33,509 | $1.29M | 0.02% | +4,385+15.1% | Added |
| State of Alaska, Department of Revenue | 33,871 | $1.31M | 0.01% | +256+0.8% | Added |
| MetLife Investment Management | 35,798 | $1.38M | 0.01% | +1,993+5.9% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 37,055 | $1.43M | 0.00% | +1,550+4.4% | Added |
| Quantedge Capital Pte Ltd | 37,200 | $1.44M | 0.52% | +4,217+12.8% | Added |
| Wells Fargo & Company | 38,796 | $1.50M | 0.00% | +9,423+32.1% | Added |
| California State Teachers Retirement System | 42,349 | $1.63M | 0.00% | −316−0.7% | Reduced |
| Thrivent Financial for Lutherans | 46,066 | $1.78M | 0.00% | −191−0.4% | Reduced |
| Birchview Capital, LP | 48,000 | $1.85M | 1.51% | 00.0% | Unchanged |
| Swedbank AB | 50,000 | $1.93M | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 50,782 | $1.96M | 0.01% | +3,622+7.7% | Added |
| Assenagon Asset Management S.A. | 52,239 | $2.02M | 0.00% | +52,239 | New |
| Knott David M Jr | 52,368 | $2.02M | 0.73% | 00.0% | Unchanged |
| Alps Advisors Inc | 55,941 | $2.16M | 0.01% | +3,909+7.5% | Added |
| Great West Life Assurance Co | 56,536 | $2.18M | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 59,998 | $2.32M | 0.00% | −800−1.3% | Reduced |
| Jane Street Group, LLC | 61,551 | $2.38M | 0.00% | +28,693+87.3% | Added |
| Great Lakes Advisors, LLC | 61,947 | $2.39M | 0.02% | −7,678−11.0% | Reduced |
| HighVista Strategies LLC | 62,518 | $2.41M | 0.90% | −26,990−30.2% | Reduced |
| Moody Aldrich Partners LLC | 67,415 | $2.60M | 0.48% | −51,872−43.5% | Reduced |
| Alliancebernstein L.P. | 68,225 | $2.63M | 0.00% | −13,694−16.7% | Reduced |
| Superstring Capital Management LP | 68,892 | $2.66M | 2.34% | +68,892 | New |
| Susquehanna International Group, LLP | 69,937 | $2.70M | 0.00% | +29,580+73.3% | Added |
| Ikarian Capital, LLC | 70,000 | $2.70M | 0.77% | +70,000 | New |
| E Fund Management Co., Ltd. | 76,087 | $2.94M | 0.15% | +4,421+6.2% | Added |
| Aquilo Capital Management, LLC | 76,592 | $2.96M | 5.06% | +76,592 | New |
| Northwestern Mutual Wealth Management Co | 78,894 | $3.05M | 0.00% | 00.0% | Unchanged |
| Voya Investment Management LLC | 82,627 | $3.19M | 0.00% | −31,225−27.4% | Reduced |
| Silvercrest Asset Management Group LLC | 84,426 | $3.26M | 0.02% | −828−1.0% | Reduced |
| Swiss National Bank | 86,900 | $3.35M | 0.00% | +1,000+1.2% | Added |
| Franklin Resources Inc | 88,870 | $3.43M | 0.00% | +7,279+8.9% | Added |
| Trexquant Investment LP | 92,788 | $3.58M | 0.04% | +69,697+301.8% | Added |
| Rafferty Asset Management, LLC | 95,467 | $3.69M | 0.01% | +5,591+6.2% | Added |
| Caption Management, LLC | 98,934 | $3.82M | 0.16% | +76,834+347.7% | Added |
| Opaleye Management Inc. | 105,000 | $4.05M | 0.71% | 00.0% | Unchanged |
| Hussman Strategic Advisors, Inc. | 105,000 | $4.05M | 1.20% | +105,000 | New |
| Citigroup Inc | 121,022 | $4.67M | 0.00% | +47,532+64.7% | Added |
| Manufacturers Life Insurance Company, The | 124,341 | $4.80M | 0.00% | +8,576+7.4% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 125,898 | $4.86M | 0.01% | 00.0% | Unchanged |
| Barclays PLC | 126,733 | $4.89M | 0.00% | −262−0.2% | Reduced |
| Jacobs Levy Equity Management, Inc | 128,654 | $4.97M | 0.02% | 00.0% | Unchanged |
| Affinity Asset Advisors, LLC | 130,000 | $5.02M | 0.78% | +130,000 | New |
| UBS Group AG | 132,609 | $5.12M | 0.00% | +53,810+68.3% | Added |
| Bank of America Corp | 134,872 | $5.21M | 0.00% | −18,645−12.1% | Reduced |
| Deutsche Bank AG | 137,932 | $5.32M | 0.00% | +17,763+14.8% | Added |
| First Trust Advisors LP | 140,951 | $5.44M | 0.00% | +270.0% | Added |
| Ameriprise Financial Inc | 141,387 | $5.46M | 0.00% | −2,420−1.7% | Reduced |
| StemPoint Capital LP | 141,714 | $5.47M | 1.37% | +141,714 | New |
| Public Sector Pension Investment Board | 148,489 | $5.73M | 0.02% | +23,540+18.8% | Added |
| AQR Capital Management LLC | 150,097 | $5.79M | 0.01% | +12,926+9.4% | Added |
| Nuveen Asset Management, LLC | 151,197 | $5.84M | 0.00% | −80,877−34.8% | Reduced |
| Legal & General Group Plc | 152,562 | $5.89M | 0.00% | −444−0.3% | Reduced |
| Man Group plc | 157,963 | $6.10M | 0.02% | +102,132+182.9% | Added |
| Rhumbline Advisers | 161,964 | $6.25M | 0.01% | −2,214−1.3% | Reduced |
| Citadel Advisors LLC | 164,146 | $6.34M | 0.01% | +159,116+3,163.3% | Added |
| TD Asset Management Inc | 173,702 | $6.70M | 0.01% | +1,500+0.9% | Added |
| Arrowstreet Capital, Limited Partnership | 216,069 | $8.34M | 0.01% | +58,002+36.7% | Added |
| Renaissance Technologies LLC | 221,167 | $8.54M | 0.01% | +77,000+53.4% | Added |
| Dimensional Fund Advisors LP | 225,600 | $8.71M | 0.00% | +110.0% | Added |
| Victory Capital Management Inc | 240,817 | $9.30M | 0.01% | +110,020+84.1% | Added |
| Soleus Capital Management, L.P. | 275,000 | $10.6M | 0.80% | +275,000 | New |