Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 185
- +28 vs. Q4 2023
- Shares held
- 60.0M
- +2.49M (+4.3%) vs. Q4 2023
- Total value
- $1.73B
- +$416.8M (+31.6%) vs. Q4 2023
- New holders
- 49
- 62 more added
- Sold out
- 21
- 56 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SEI Investments Co | 41,758 | $1.21M | 0.00% | +4,529+12.2% | Added |
| Millennium Management LLC | 42,865 | $1.24M | 0.00% | −106,298−71.3% | Reduced |
| Citadel Advisors LLC | 45,616 | $1.32M | 0.00% | −2,248−4.7% | Reduced |
| BNP Paribas Arbitrage, SA | 47,233 | $1.37M | 0.00% | −24,665−34.3% | Reduced |
| California State Teachers Retirement System | 47,239 | $1.37M | 0.00% | −3,153−6.3% | Reduced |
| Birchview Capital, LP | 48,000 | $1.39M | 1.13% | 00.0% | Unchanged |
| Legal & General Group Plc | 50,686 | $1.47M | 0.00% | +5,397+11.9% | Added |
| Knott David M Jr | 52,368 | $1.51M | 0.54% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 55,359 | $1.60M | 0.13% | +35,571+179.8% | Added |
| First Trust Advisors LP | 60,663 | $1.75M | 0.00% | +60,663 | New |
| Barclays PLC | 61,819 | $1.79M | 0.00% | −87,155−58.5% | Reduced |
| Qube Research & Technologies Ltd | 62,155 | $1.80M | 0.00% | +62,155 | New |
| Credit Suisse AG | 63,024 | $1.82M | 0.00% | +507+0.8% | Added |
| Voya Investment Management LLC | 69,443 | $2.01M | 0.00% | +26,198+60.6% | Added |
| Susquehanna International Group, LLP | 71,818 | $2.08M | 0.00% | −37,865−34.5% | Reduced |
| Ghost Tree Capital, LLC | 75,000 | $2.17M | 0.70% | −50,000−40.0% | Reduced |
| AQR Capital Management LLC | 81,007 | $2.34M | 0.00% | +71,665+767.1% | Added |
| Jane Street Group, LLC | 81,270 | $2.35M | 0.00% | +8,339+11.4% | Added |
| Rhumbline Advisers | 84,989 | $2.46M | 0.00% | +1,697+2.0% | Added |
| Alliancebernstein L.P. | 85,400 | $2.47M | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Inc. | 87,000 | $2.52M | 0.01% | +87,000 | New |
| Manufacturers Life Insurance Company, The | 89,657 | $2.59M | 0.00% | +21,225+31.0% | Added |
| Swiss National Bank | 90,700 | $2.62M | 0.00% | 00.0% | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. | 93,186 | $2.70M | 0.01% | −14,356−13.3% | Reduced |
| Great Lakes Advisors, LLC | 97,160 | $2.81M | 0.02% | +6,007+6.6% | Added |
| Affinity Asset Advisors, LLC | 100,000 | $2.89M | 0.47% | +100,000 | New |
| Moody Aldrich Partners LLC | 100,519 | $2.91M | 0.49% | +38,192+61.3% | Added |
| Trexquant Investment LP | 102,379 | $2.96M | 0.06% | +102,379 | New |
| TD Asset Management Inc | 108,452 | $3.14M | 0.00% | −2,348−2.1% | Reduced |
| UBS Oconnor LLC | 109,330 | $3.16M | 0.09% | +3,176+3.0% | Added |
| Opaleye Management Inc. | 112,700 | $3.26M | 0.71% | 00.0% | Unchanged |
| HSBC Holdings PLC | 112,887 | $3.27M | 0.00% | −6,447−5.4% | Reduced |
| Privium Fund Management B.V. | 114,024 | $3.30M | 0.88% | +114,024 | New |
| Artia Global Partners LP | 124,440 | $3.60M | 0.88% | +12,100+10.8% | Added |
| Jacobs Levy Equity Management, Inc | 129,011 | $3.73M | 0.02% | 00.0% | Unchanged |
| Walleye Capital LLC | 134,114 | $3.88M | 0.04% | −51,312−27.7% | Reduced |
| Algert Global LLC | 147,843 | $4.28M | 0.17% | +72,083+95.1% | Added |
| Two Sigma Investments, LP | 157,594 | $4.56M | 0.01% | −1,249−0.8% | Reduced |
| American Century Companies Inc | 160,320 | $4.64M | 0.00% | +121,976+318.1% | Added |
| UBS Group AG | 177,546 | $5.14M | 0.00% | +26,679+17.7% | Added |
| Bank of New York Mellon Corp | 187,234 | $5.42M | 0.00% | −15,943−7.8% | Reduced |
| Silvercrest Asset Management Group LLC | 188,743 | $5.46M | 0.04% | +8,247+4.6% | Added |
| Two Sigma Advisers, LP | 196,700 | $5.69M | 0.01% | −25,300−11.4% | Reduced |
| Rubric Capital Management LP | 198,059 | $5.73M | 0.17% | +198,059 | New |
| CIBC World Markets Corp | 200,000 | $5.79M | 0.04% | +200,000 | New |
| Citigroup Inc | 208,641 | $6.04M | 0.01% | +135,938+187.0% | Added |
| JPMorgan Chase & Co | 237,440 | $6.87M | 0.00% | −173,606−42.2% | Reduced |
| Rafferty Asset Management, LLC | 239,208 | $6.92M | 0.03% | +71,413+42.6% | Added |
| Bank of America Corp | 266,551 | $7.71M | 0.00% | +113,142+73.8% | Added |
| Checkpoint Capital L.P. | 280,301 | $8.11M | 5.42% | +13,445+5.0% | Added |
| Kennedy Capital Management, Inc. | 298,068 | $8.62M | 0.18% | −6,722−2.2% | Reduced |
| UBS Asset Management Americas Inc | 335,318 | $9.70M | 0.00% | +46,239+16.0% | Added |
| Candriam Luxembourg S.C.A. | 360,000 | $10.4M | 0.07% | −177,000−33.0% | Reduced |
| Gratus Capital LLC | 408,173 | $11.8M | 0.54% | +10,602+2.7% | Added |
| Eversept Partners, LP | 411,478 | $11.9M | 0.89% | −126,596−23.5% | Reduced |
| Mangrove Partners | 439,314 | $12.7M | 1.10% | 00.0% | Unchanged |
| FMR LLC | 466,085 | $13.5M | 0.00% | +1330.0% | Added |
| Charles Schwab Investment Management Inc | 496,562 | $14.4M | 0.00% | +41,241+9.1% | Added |
| Goldman Sachs Group Inc | 525,040 | $15.2M | 0.00% | +9,820+1.9% | Added |
| Northern Trust Corp | 538,995 | $15.6M | 0.00% | −11,144−2.0% | Reduced |
| Driehaus Capital Management LLC | 560,530 | $16.2M | 0.16% | +361,841+182.1% | Added |
| Woodline Partners LP | 636,956 | $18.4M | 0.17% | +636,956 | New |
| Nuveen Asset Management, LLC | 678,201 | $19.6M | 0.01% | +372,782+122.1% | Added |
| 683 Capital Management, LLC | 700,000 | $20.3M | 2.07% | −15,000−2.1% | Reduced |
| ADAR1 Capital Management, LLC | 785,655 | $22.7M | 6.21% | +584,796+291.1% | Added |
| Dimensional Fund Advisors LP | 791,344 | $22.9M | 0.01% | −25,193−3.1% | Reduced |
| Price T Rowe Associates Inc | 819,296 | $23.7M | 0.00% | −4,444−0.5% | Reduced |
| Deutsche Bank AG | 910,806 | $26.3M | 0.01% | +794+0.1% | Added |
| Fairmount Funds Management LLC | 931,890 | $27.0M | 2.94% | +931,890 | New |
| Marshall Wace, LLP | 976,893 | $28.3M | 0.05% | +834,423+585.7% | Added |
| Perceptive Advisors LLC | 994,323 | $28.8M | 0.51% | +611,063+159.4% | Added |
| Kynam Capital Management, LP | 1,144,242 | $33.1M | 3.68% | −860,633−42.9% | Reduced |
| Jefferies Financial Group Inc. | 1,180,561 | $34.2M | 0.69% | −90,000−7.1% | Reduced |
| Point72 Asset Management, L.P. | 1,199,902 | $34.7M | 0.10% | −1,413,551−54.1% | Reduced |
| Geode Capital Management, LLC | 1,293,739 | $37.4M | 0.00% | +45,455+3.6% | Added |
| Cowen and Company, LLC | 1,557,636 | $45.1M | 1.76% | +1,557,636 | New |
| Morgan Stanley | 1,879,878 | $54.4M | 0.00% | +688,041+57.7% | Added |
| Adage Capital Partners GP, L.L.C. | 2,218,868 | $64.2M | 0.12% | +927,167+71.8% | Added |
| Johnson & Johnson | 2,449,183 | $70.9M | 1.61% | 00.0% | Unchanged |
| Vanguard Group Inc | 3,192,971 | $92.4M | 0.00% | +39,055+1.2% | Added |
| State Street Corp | 3,272,485 | $94.7M | 0.00% | +542,556+19.9% | Added |
| BVF Inc | 3,755,990 | $108.7M | 2.99% | −1,988,858−34.6% | Reduced |
| RTW Investments, LP | 5,315,514 | $153.8M | 2.27% | 00.0% | Unchanged |
| BlackRock Inc. | 5,569,485 | $161.1M | 0.00% | +25,583+0.5% | Added |
| Farallon Capital Management, L.L.C. | 5,738,973 | $166.0M | 0.98% | +4,543+0.1% | Added |
| StemPoint Capital LP | 0 | $0 | 0.00% | −513,681−100.0% | Sold out |
| Sio Capital Management, LLC | 0 | $0 | 0.00% | −460,044−100.0% | Sold out |
| Superstring Capital Management LP | 0 | $0 | 0.00% | −379,143−100.0% | Sold out |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −319,000−100.0% | Sold out |
| Deep Track Capital, LP | 0 | $0 | 0.00% | −275,201−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −89,113−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −80,607−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −73,126−100.0% | Sold out |
| Readystate Asset Management LP | 0 | $0 | 0.00% | −57,206−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −50,503−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −31,275−100.0% | Sold out |
| Schroder Investment Management Group | 0 | $0 | 0.00% | −19,900−100.0% | Sold out |
| Bayesian Capital Management, LP | 0 | $0 | 0.00% | −12,661−100.0% | Sold out |
| Chartwell Investment Partners, LLC | 0 | $0 | 0.00% | −12,098−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −11,806−100.0% | Sold out |