Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 157
- +14 vs. Q3 2023
- Shares held
- 57.5M
- +792.3K (+1.4%) vs. Q3 2023
- Total value
- $1.32B
- +$372.5M (+39.4%) vs. Q3 2023
- New holders
- 33
- 40 more added
- Sold out
- 19
- 60 more reduced
1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Susquehanna International Group, LLP | 109,683 | $2.52M | 0.00% | +52,438+91.6% | Added |
| TD Asset Management Inc | 110,800 | $2.54M | 0.00% | 00.0% | Unchanged |
| Artia Global Partners LP | 112,340 | $2.58M | 1.02% | 00.0% | Unchanged |
| Opaleye Management Inc. | 112,700 | $2.58M | 0.69% | +112,700 | New |
| HSBC Holdings PLC | 119,334 | $2.74M | 0.00% | −434,971−78.5% | Reduced |
| Ghost Tree Capital, LLC | 125,000 | $2.87M | 1.65% | −275,000−68.8% | Reduced |
| Jacobs Levy Equity Management, Inc | 129,011 | $2.96M | 0.01% | 00.0% | Unchanged |
| Marshall Wace, LLP | 142,470 | $3.27M | 0.01% | +120,723+555.1% | Added |
| Barclays PLC | 148,974 | $3.42M | 0.00% | −27,863−15.8% | Reduced |
| Millennium Management LLC | 149,163 | $3.42M | 0.00% | +149,163 | New |
| UBS Group AG | 150,867 | $3.46M | 0.00% | +60,141+66.3% | Added |
| Bank of America Corp | 153,409 | $3.52M | 0.00% | −85,629−35.8% | Reduced |
| Two Sigma Investments, LP | 158,843 | $3.64M | 0.01% | −177,465−52.8% | Reduced |
| Rafferty Asset Management, LLC | 167,795 | $3.85M | 0.02% | −182,486−52.1% | Reduced |
| Silvercrest Asset Management Group LLC | 180,496 | $4.14M | 0.03% | +340.0% | Added |
| Walleye Capital LLC | 185,426 | $4.25M | 0.06% | +51,610+38.6% | Added |
| Driehaus Capital Management LLC | 198,689 | $4.56M | 0.05% | +198,689 | New |
| ADAR1 Capital Management, LLC | 200,859 | $4.61M | 2.06% | +200,859 | New |
| Bank of New York Mellon Corp | 203,177 | $4.66M | 0.00% | +1,733+0.9% | Added |
| Renaissance Technologies LLC | 213,967 | $4.91M | 0.01% | −12,301−5.4% | Reduced |
| Two Sigma Advisers, LP | 222,000 | $5.09M | 0.01% | −94,900−29.9% | Reduced |
| Checkpoint Capital L.P. | 266,856 | $6.12M | 4.27% | +266,856 | New |
| Deep Track Capital, LP | 275,201 | $6.31M | 0.22% | +275,201 | New |
| UBS Asset Management Americas Inc | 289,079 | $6.63M | 0.00% | +218,020+306.8% | Added |
| Kennedy Capital Management, Inc. | 304,790 | $6.99M | 0.15% | −14,744−4.6% | Reduced |
| Nuveen Asset Management, LLC | 305,419 | $7.00M | 0.00% | −230,605−43.0% | Reduced |
| Ikarian Capital, LLC | 319,000 | $7.31M | 2.00% | +319,000 | New |
| Superstring Capital Management LP | 379,143 | $8.69M | 6.21% | +379,143 | New |
| Perceptive Advisors LLC | 383,260 | $8.79M | 0.20% | −671,013−63.6% | Reduced |
| Gratus Capital LLC | 397,571 | $9.12M | 0.52% | +104,702+35.8% | Added |
| JPMorgan Chase & Co | 411,046 | $9.43M | 0.00% | +178,756+77.0% | Added |
| Mangrove Partners | 439,314 | $10.1M | 0.87% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 455,321 | $10.4M | 0.00% | +16,219+3.7% | Added |
| Sio Capital Management, LLC | 460,044 | $10.5M | 2.72% | +211,917+85.4% | Added |
| FMR LLC | 465,952 | $10.7M | 0.00% | −43,290−8.5% | Reduced |
| StemPoint Capital LP | 513,681 | $11.8M | 3.17% | +513,681 | New |
| Goldman Sachs Group Inc | 515,220 | $11.8M | 0.00% | +48,017+10.3% | Added |
| Candriam Luxembourg S.C.A. | 537,000 | $12.3M | 0.08% | −93,000−14.8% | Reduced |
| Eversept Partners, LP | 538,074 | $12.3M | 1.21% | +251,326+87.6% | Added |
| Northern Trust Corp | 550,139 | $12.6M | 0.00% | −12,549−2.2% | Reduced |
| 683 Capital Management, LLC | 715,000 | $16.4M | 1.64% | −17,784−2.4% | Reduced |
| Dimensional Fund Advisors LP | 816,537 | $18.7M | 0.01% | −124,737−13.3% | Reduced |
| Price T Rowe Associates Inc | 823,740 | $18.9M | 0.00% | −8,253−1.0% | Reduced |
| Deutsche Bank AG | 910,012 | $20.9M | 0.01% | +838,099+1,165.4% | Added |
| Morgan Stanley | 1,191,837 | $27.3M | 0.00% | +762,833+177.8% | Added |
| Geode Capital Management, LLC | 1,248,284 | $28.6M | 0.00% | +67,028+5.7% | Added |
| Jefferies Financial Group Inc. | 1,270,561 | $29.1M | 0.46% | +435,000+52.1% | Added |
| Adage Capital Partners GP, L.L.C. | 1,291,701 | $29.6M | 0.06% | +591,701+84.5% | Added |
| Kynam Capital Management, LP | 2,004,875 | $46.0M | 5.20% | +186,218+10.2% | Added |
| Johnson & Johnson | 2,449,183 | $56.2M | 1.28% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 2,613,453 | $59.9M | 0.18% | +1,505,313+135.8% | Added |
| State Street Corp | 2,729,929 | $62.6M | 0.00% | −1,212,209−30.8% | Reduced |
| Vanguard Group Inc | 3,153,916 | $72.3M | 0.00% | −74,478−2.3% | Reduced |
| RTW Investments, LP | 5,315,514 | $121.9M | 1.90% | −100,000−1.8% | Reduced |
| BlackRock Inc. | 5,543,902 | $127.1M | 0.00% | +314,477+6.0% | Added |
| Farallon Capital Management, L.L.C. | 5,734,430 | $131.5M | 0.82% | +288,000+5.3% | Added |
| BVF Inc | 5,744,848 | $131.7M | 3.30% | 00.0% | Unchanged |
| Cowen and Company, LLC | 0 | $0 | 0.00% | −1,657,551−100.0% | Sold out |
| Braidwell LP | 0 | $0 | 0.00% | −1,109,150−100.0% | Sold out |
| Eventide Asset Management, LLC | 0 | $0 | 0.00% | −320,000−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −177,125−100.0% | Sold out |
| Suvretta Capital Management, LLC | 0 | $0 | 0.00% | −108,308−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −91,735−100.0% | Sold out |
| Healthcare of Ontario Pension Plan Trust Fund | 0 | $0 | 0.00% | −88,000−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −60,234−100.0% | Sold out |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −56,577−100.0% | Sold out |
| Ghisallo Capital Management LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Public Sector Pension Investment Board | 0 | $0 | 0.00% | −49,000−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −35,438−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −16,139−100.0% | Sold out |
| Capital Fund Management S.A. | 0 | $0 | 0.00% | −12,629−100.0% | Sold out |
| Franklin Resources Inc | 0 | $0 | 0.00% | −11,853−100.0% | Sold out |
| Sawtooth Solutions, LLC | 0 | $0 | 0.00% | −10,411−100.0% | Sold out |
| Bleakley Financial Group, LLC | 0 | $0 | 0.00% | −10,411−100.0% | Sold out |
| Russell Investments Group, Ltd. | 0 | $0 | 0.00% | −12−100.0% | Sold out |
| CWM, LLC | 0 | $0 | 0.00% | −7−100.0% | Sold out |
| International Biotechnology Trust PLC | – | – | – | – | Not filed |