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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2023

Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
144
−23 vs. Q2 2023
Shares held
56.7M
−20.1K (0.0%) vs. Q2 2023
Total value
$945.9M
−$621.0M (−39.6%) vs. Q2 2023
New holders
17
65 more added
Sold out
40
40 more reduced

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 144 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ3 2023: $945.9M
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2023.

Institutions holding PTGX in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Barclays PLC176,837$2.95M0.00%−16,602−8.6%Reduced
ExodusPoint Capital Management, LP177,125$2.95M0.04%+162,471+1,108.7%Added
Silvercrest Asset Management Group LLC180,462$3.01M0.02%+52,265+40.8%Added
Readystate Asset Management LP184,347$3.07M0.26%−20,533−10.0%Reduced
Bank of New York Mellon Corp201,444$3.36M0.00%+1,869+0.9%Added
Renaissance Technologies LLC226,268$3.77M0.01%−163,999−42.0%Reduced
JPMorgan Chase & Co232,290$3.87M0.00%−32,417−12.2%Reduced
Bank of America Corp239,038$3.99M0.00%−57,202−19.3%Reduced
Sio Capital Management, LLC248,127$4.14M1.28%+248,127New
Eversept Partners, LP286,748$4.78M0.53%+172,089+150.1%Added
Gratus Capital LLC292,869$4.89M0.33%+73,283+33.4%Added
Two Sigma Advisers, LP316,900$5.29M0.01%−95,200−23.1%Reduced
Kennedy Capital Management, Inc.319,534$5.33M0.13%−84,114−20.8%Reduced
Eventide Asset Management, LLC320,000$5.34M0.10%00.0%Unchanged
Two Sigma Investments, LP336,308$5.61M0.02%−40,165−10.7%Reduced
Rafferty Asset Management, LLC350,281$5.84M0.03%+64,822+22.7%Added
Ghost Tree Capital, LLC400,000$6.67M3.23%+175,000+77.8%Added
Morgan Stanley429,004$7.16M0.00%−149,017−25.8%Reduced
Charles Schwab Investment Management Inc439,102$7.32M0.00%+19,492+4.6%Added
Mangrove Partners439,314$7.33M0.75%+439,314New
Goldman Sachs Group Inc467,203$7.79M0.00%−92,007−16.5%Reduced
FMR LLC509,242$8.49M0.00%+1,835+0.4%Added
Nuveen Asset Management, LLC536,024$8.94M0.00%−399,937−42.7%Reduced
HSBC Holdings PLC554,305$9.17M0.01%−6,150−1.1%Reduced
Northern Trust Corp562,688$9.39M0.00%+24,563+4.6%Added
Candriam Luxembourg S.C.A.630,000$10.5M0.09%−95,000−13.1%Reduced
Adage Capital Partners GP, L.L.C.700,000$11.7M0.03%−592,711−45.9%Reduced
683 Capital Management, LLC732,784$12.2M1.24%−81,216−10.0%Reduced
Price T Rowe Associates Inc831,993$13.9M0.00%+3000.0%Added
Jefferies Financial Group Inc.835,561$13.9M0.35%+75,000+9.9%Added
Dimensional Fund Advisors LP941,274$15.7M0.01%−97,831−9.4%Reduced
Perceptive Advisors LLC1,054,273$17.6M0.59%−415,488−28.3%Reduced
Point72 Asset Management, L.P.1,108,140$18.5M0.06%+1,108,140New
Braidwell LP1,109,150$18.5M0.58%+1,109,150New
Geode Capital Management, LLC1,181,256$19.7M0.00%+104,072+9.7%Added
Cowen and Company, LLC1,657,551$27.6M1.94%00.0%Unchanged
Kynam Capital Management, LP1,818,657$30.3M5.04%+843,359+86.5%Added
Johnson & Johnson2,449,183$40.9M15.05%00.0%Unchanged
Vanguard Group Inc3,228,394$53.8M0.00%+80,639+2.6%Added
State Street Corp3,942,138$65.8M0.00%+390,152+11.0%Added
BlackRock Inc.5,229,425$87.2M0.00%+220,152+4.4%Added
RTW Investments, LP5,415,514$90.3M1.91%00.0%Unchanged
Farallon Capital Management, L.L.C.5,446,430$90.8M0.51%+935,000+20.7%Added
BVF Inc5,744,848$95.8M2.58%+1,968,948+52.1%Added
Cormorant Asset Management, LP0$00.00%−1,500,000−100.0%Sold out
Holocene Advisors, LP0$00.00%−802,531−100.0%Sold out
Artal Group S.A.0$00.00%−500,000−100.0%Sold out
Woodline Partners LP0$00.00%−427,264−100.0%Sold out
Millennium Management LLC0$00.00%−351,810−100.0%Sold out
Bank of Montreal0$00.00%−310,000−100.0%Sold out
SG Americas Securities, LLC0$00.00%−195,756−100.0%Sold out
Ameriprise Financial Inc0$00.00%−99,930−100.0%Sold out
EAM Investors, LLC0$00.00%−87,953−100.0%Sold out
Integral Health Asset Management, LLC0$00.00%−75,000−100.0%Sold out
Thrivent Financial for Lutherans0$00.00%−73,381−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−72,686−100.0%Sold out
Harvest Investment Services, LLC0$00.00%−44,113−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−39,800−100.0%Sold out
Ikarian Capital, LLC0$00.00%−35,000−100.0%Sold out
Tri Locum Partners LP0$00.00%−33,750−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−33,338−100.0%Sold out
HighVista Strategies LLC0$00.00%−29,179−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−27,931−100.0%Sold out
Seven Eight Capital, LP0$00.00%−27,092−100.0%Sold out
Simplex Trading, LLC0$00.00%−25,214−100.0%Sold out
Silverarc Capital Management, LLC0$00.00%−25,000−100.0%Sold out
Moore Capital Management, LP0$00.00%−22,580−100.0%Sold out
Fred Alger Management, LLC0$00.00%−21,719−100.0%Sold out
Caption Management, LLC0$00.00%−19,140−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−15,588−100.0%Sold out
Arrowstreet Capital, Limited Partnership0$00.00%−14,895−100.0%Sold out
American Century Companies Inc0$00.00%−14,339−100.0%Sold out
AXA S.A.0$00.00%−11,900−100.0%Sold out
Trexquant Investment LP0$00.00%−11,413−100.0%Sold out
Zacks Investment Management0$00.00%−11,168−100.0%Sold out
Mackenzie Financial Corp0$00.00%−12,745−100.0%Sold out
Los Angeles Capital Management LLC0$00.00%−9,366−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−9,211−100.0%Sold out
Verition Fund Management LLC0$00.00%−9,210−100.0%Sold out
Aigen Investment Management, LP0$00.00%−7,527−100.0%Sold out
GWM Advisors LLC0$00.00%−3,230−100.0%Sold out
Leonteq Securities AG0$00.00%−470−100.0%Sold out
Signaturefd, LLC0$00.00%−33−100.0%Sold out
Sofos Investments, Inc.0$00.00%−28−100.0%Sold out