Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 137
- +5 vs. Q3 2022
- Shares held
- 48.9M
- +1.68M (+3.5%) vs. Q3 2022
- Total value
- $533.3M
- +$135.4M (+34.0%) vs. Q3 2022
- New holders
- 21
- 51 more added
- Sold out
- 16
- 43 more reduced
1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Silvercrest Asset Management Group LLC | 240,745 | $2.63M | 0.02% | −2,268−0.9% | Reduced |
| Barclays PLC | 254,887 | $2.78M | 0.00% | +38,893+18.0% | Added |
| Renaissance Technologies LLC | 258,867 | $2.82M | 0.00% | −140,900−35.2% | Reduced |
| Jacobs Levy Equity Management, Inc | 284,115 | $3.10M | 0.02% | +29,775+11.7% | Added |
| Rafferty Asset Management, LLC | 295,348 | $3.22M | 0.03% | −51,587−14.9% | Reduced |
| JPMorgan Chase & Co | 303,162 | $3.31M | 0.00% | +127,603+72.7% | Added |
| Point72 Asset Management, L.P. | 316,500 | $3.45M | 0.01% | −2,221,493−87.5% | Reduced |
| Charles Schwab Investment Management Inc | 340,021 | $3.71M | 0.00% | +6,378+1.9% | Added |
| Bank of America Corp | 344,947 | $3.76M | 0.00% | +34,898+11.3% | Added |
| Kennedy Capital Management, Inc. | 350,133 | $3.82M | 0.11% | +251,046+253.4% | Added |
| Nuveen Asset Management, LLC | 360,714 | $3.94M | 0.00% | +22,170+6.5% | Added |
| Madison Avenue Partners, LP | 406,593 | $4.44M | 0.79% | +406,593 | New |
| Northern Trust Corp | 418,607 | $4.57M | 0.00% | +824+0.2% | Added |
| Sio Capital Management, LLC | 434,635 | $4.74M | 2.53% | +434,635 | New |
| Two Sigma Investments, LP | 491,965 | $5.37M | 0.02% | +246,260+100.2% | Added |
| Woodline Partners LP | 512,140 | $5.59M | 0.08% | +512,140 | New |
| Kynam Capital Management, LP | 520,922 | $5.68M | 0.87% | +1,710+0.3% | Added |
| Walleye Capital LLC | 524,302 | $5.72M | 0.12% | +421,359+409.3% | Added |
| Two Sigma Advisers, LP | 603,500 | $6.58M | 0.02% | +196,200+48.2% | Added |
| Goldman Sachs Group Inc | 616,724 | $6.73M | 0.00% | −140,355−18.5% | Reduced |
| Adage Capital Partners GP, L.L.C. | 767,045 | $8.37M | 0.02% | −106,000−12.1% | Reduced |
| Deep Track Capital, LP | 871,493 | $9.51M | 0.41% | +871,493 | New |
| Geode Capital Management, LLC | 879,891 | $9.60M | 0.00% | +52,435+6.3% | Added |
| Deutsche Bank AG | 925,662 | $10.1M | 0.01% | +113,307+13.9% | Added |
| Braidwell LP | 927,800 | $10.1M | 0.34% | +927,800 | New |
| Dimensional Fund Advisors LP | 1,077,226 | $11.8M | 0.00% | +256,788+31.3% | Added |
| Millennium Management LLC | 1,345,389 | $14.7M | 0.02% | +1,147,367+579.4% | Added |
| Marshall Wace, LLP | 1,454,446 | $15.9M | 0.04% | +639,720+78.5% | Added |
| Citadel Advisors LLC | 2,355,314 | $25.7M | 0.03% | +1,488,927+171.9% | Added |
| Bain Capital Life Sciences Investors, LLC | 2,364,410 | $25.8M | 2.88% | +103,838+4.6% | Added |
| Morgan Stanley | 2,438,517 | $26.6M | 0.00% | +210,942+9.5% | Added |
| Johnson & Johnson | 2,449,183 | $26.7M | 7.77% | 00.0% | Unchanged |
| Vanguard Group Inc | 3,097,714 | $33.8M | 0.00% | +154,947+5.3% | Added |
| RTW Investments, LP | 3,591,986 | $39.2M | 0.80% | −584,851−14.0% | Reduced |
| Farallon Capital Management, L.L.C. | 3,651,887 | $39.8M | 0.26% | 00.0% | Unchanged |
| BlackRock Inc. | 3,652,157 | $39.8M | 0.00% | +189,773+5.5% | Added |
| State Street Corp | 3,792,926 | $41.4M | 0.00% | −883,756−18.9% | Reduced |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −232,820−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −53,443−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −53,190−100.0% | Sold out |
| Skandinaviska Enskilda Banken AB (publ) | 0 | $0 | 0.00% | −48,977−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −33,498−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −31,814−100.0% | Sold out |
| UBS Asset Management Americas Inc | 0 | $0 | 0.00% | −27,275−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −24,332−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −22,421−100.0% | Sold out |
| Ensign Peak Advisors, Inc | 0 | $0 | 0.00% | −12,270−100.0% | Sold out |
| Bridgefront Capital, LLC | 0 | $0 | 0.00% | −12,084−100.0% | Sold out |
| Dark Forest Capital Management LP | 0 | $0 | 0.00% | −1,582−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −1,112−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −755−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | 0 | Sold out |
| TCI Wealth Advisors, Inc. | 0 | $0 | 0.00% | −387−100.0% | Sold out |
| Jefferies Group LLC | – | – | – | – | Not filed |