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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q4 2021

Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
149
+17 vs. Q3 2021
Shares held
49.4M
+3.04M (+6.6%) vs. Q3 2021
Total value
$1.68B
+$863.7M (+105.2%) vs. Q3 2021
New holders
36
58 more added
Sold out
19
36 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 149 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ4 2021: $1.68B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2021.

Institutions holding PTGX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Susquehanna Fundamental Investments, LLC18,524$634.0K0.02%+5,509+42.3%Added
Voya Investment Management LLC17,368$594.0K0.00%−69−0.4%Reduced
ProShare Advisors LLC16,489$564.0K0.00%+597+3.8%Added
PDT Partners, LLC16,018$548.0K0.04%−13,682−46.1%Reduced
Putnam Investments LLC15,484$529.0K0.00%+15,484New
AQR Capital Management LLC15,177$519.0K0.00%−26,500−63.6%Reduced
MetLife Investment Management15,088$516.0K0.00%00.0%Unchanged
STRS Ohio13,200$451.0K0.00%00.0%Unchanged
Quantbot Technologies LP13,104$448.0K0.04%+13,104New
DekaBank Deutsche Girozentrale14,400$439.0K0.00%+400+2.9%Added
Metropolitan Life Insurance Co11,747$401.7K0.01%00.0%Unchanged
Arizona State Retirement System11,518$394.0K0.00%+745+6.9%Added
State Board of Administration of Florida Retirement System10,953$375.0K0.00%+125+1.2%Added
Ensign Peak Advisors, Inc10,680$365.0K0.00%+10,680New
Belvedere Trading LLC11,948$350.0K0.08%+763+6.8%Added
Royal Bank of Canada10,067$345.0K0.00%+5,282+110.4%Added
Victory Capital Management Inc9,612$329.0K0.00%+9,612New
Tower Research Capital LLC (TRC)8,835$302.0K0.01%−3,298−27.2%Reduced
Teacher Retirement System of Texas8,464$289.0K0.00%+8,464New
Janus Henderson Group PLC8,014$274.0K0.00%+8,014New
Amalgamated Bank7,879$269.0K0.00%+7,879New
Kestra Advisory Services, LLC7,833$268.0K0.00%+7,833New
Principal Financial Group Inc7,607$260.0K0.00%+7,607New
Gladstone Institutional Advisory LLC7,506$257.0K0.02%+7,506New
Coastal Bridge Advisors, LLC7,400$254.0K0.05%+7,400New
Panagora Asset Management Inc7,225$247.0K0.00%−24,212−77.0%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)6,293$215.0K0.00%+3,864+159.1%Added
Virtus ETF Advisers LLC5,521$189.0K0.07%+351+6.8%Added
Kessler Investment Group, LLC5,165$177.0K0.10%00.0%Unchanged
Amundi4,053$141.0K0.00%+4,053New
Ameritas Investment Partners, Inc.3,501$120.0K0.00%+260+8.0%Added
Cowen and Company, LLC3,178$109.0K0.01%+3,178New
Great West Life Assurance Co1,982$68.0K0.00%00.0%Unchanged
Simplex Trading, LLC1,804$61.0K0.00%+1,804New
Central Trust Co1,625$56.0K0.00%+1,625New
Captrust Financial Advisors1,153$39.0K0.00%+1,110+2,581.4%Added
Eagle Bay Advisors LLC1,000$34.0K0.02%−240−19.4%Reduced
Cubist Systematic Strategies, LLC546$19.0K0.00%−571−51.1%Reduced
Cutler Group LP584$19.0K0.00%+484+484.0%Added
Leonteq Securities AG470$16.1K0.00%+470New
Macquarie Group Ltd307$10.0K0.00%00.0%Unchanged
US Bancorp278$10.0K0.00%+14+5.3%Added
Truvestments Capital LLC250$9.00K0.00%00.0%Unchanged
TCI Wealth Advisors, Inc.219$7.00K0.00%+73+50.0%Added
Daiwa Securities Group Inc.163$6.00K0.00%00.0%Unchanged
Signaturefd, LLC46$2.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.57$2.00K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co16$1.00K0.00%+16New
Covestor Ltd14$00.00%+14New
Sphera Funds Management Ltd.0$00.00%−260,379−100.0%Sold out
Federated Hermes, Inc.0$00.00%−131,282−100.0%Sold out
Jabodon PT Co0$00.00%−90,656−100.0%Sold out
Sio Capital Management, LLC0$00.00%−90,000−100.0%Sold out
State of New Jersey Common Pension Fund D0$00.00%−54,589−100.0%Sold out
Cinctive Capital Management LP0$00.00%−40,387−100.0%Sold out
Integral Health Asset Management, LLC0$00.00%−35,000−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−23,876−100.0%Sold out
Martingale Asset Management L P0$00.00%−17,408−100.0%Sold out
Bellwether Advisors, LLC0$00.00%−13,630−100.0%Sold out
Bingham Osborn & Scarborough LLC0$00.00%−11,640−100.0%Sold out
SG3 Management, LLC0$00.00%−10,000−100.0%Sold out
Lindbrook Capital, LLC0$00.00%−2,450−100.0%Sold out
O'Shaughnessy Asset Management, LLC0$00.00%−2,162−100.0%Sold out
Group One Trading, L.P.0$00.00%−1,800−100.0%Sold out
Penserra Capital Management LLC0$00.00%−1,090−100.0%Sold out
Harbour Investments, Inc.0$00.00%−126−100.0%Sold out
Ellevest, Inc.0$00.00%−6−100.0%Sold out
State of Wyoming0$00.00%−26−100.0%Sold out