Karyopharm Therapeutics Inc.
KPTI- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
In the last 90 days, Karyopharm Therapeutics Inc. insiders filed 0 open-market purchases and 2 sales; 96 institutions reported holding it in 13F filings for Q2 2026, worth $206.8M in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Karyopharm Therapeutics Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 96
- +19 vs. Q1 2026
- Shares held
- 21.2M
- +3.49M (+19.8%) vs. Q1 2026
- Total value
- $206.8M
- +$108.4M (+110.1%) vs. Q1 2026
- New holders
- 33
- 31 more added
- Sold out
- 14
- 14 more reduced
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KPTI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 96 | $206.8M |
| Q1 2026 | 77 | $98.4M |
| Q4 2025 | 68 | $69.6M |
| Q3 2025 | 52 | $19.5M |
| Q2 2025 | 50 | $19.0M |
| Q1 2025 | 50 | $13.7M |
| Q4 2024 | 87 | $41.2M |
| Q3 2024 | 91 | $49.2M |
| Q2 2024 | 114 | $58.6M |
| Q1 2024 | 114 | $113.0M |
| Q4 2023 | 120 | $63.5M |
| Q3 2023 | 120 | $102.8M |
| Q2 2023 | 138 | $145.0M |
| Q1 2023 | 132 | $340.1M |
| Q4 2022 | 155 | $334.4M |
| Q3 2022 | 147 | $364.1M |
| Q2 2022 | 150 | $302.8M |
| Q1 2022 | 139 | $501.8M |
| Q4 2021 | 143 | $347.5M |
| Q3 2021 | 134 | $334.4M |
| Q2 2021 | 154 | $608.7M |
| Q1 2021 | 171 | $637.1M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Karyopharm Therapeutics Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −136,736−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −70,748−100.0% | Sold out |
| Polygon Management Ltd. | 0 | $0 | 0.00% | −52,984−100.0% | Sold out |
| DAFNA Capital Management LLC | 0 | $0 | 0.00% | −45,800−100.0% | Sold out |
| Zimmer Partners, LP | 0 | $0 | 0.00% | −37,500−100.0% | Sold out |
| Centiva Capital, LP | 0 | $0 | 0.00% | −30,210−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −24,138−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −19,400−100.0% | Sold out |
| Rockefeller Capital Management L.P. | 0 | $0 | 0.00% | −733−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −12−100.0% | Sold out |