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Karyopharm Therapeutics Inc.

KPTI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001503802

In the last 90 days, Karyopharm Therapeutics Inc. insiders filed 0 open-market purchases and 2 sales; 96 institutions reported holding it in 13F filings for Q2 2026, worth $206.8M in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Karyopharm Therapeutics Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
91
−21 vs. Q2 2024
Shares held
59.4M
−3.98M (−6.3%) vs. Q2 2024
Total value
$49.2M
−$5.79M (−10.5%) vs. Q2 2024
New holders
10
21 more added
Sold out
31
29 more reduced

2 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KPTI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 91 institutions
Q1 2021: 171 institutionsQ2 2021: 154 institutionsQ3 2021: 134 institutionsQ4 2021: 143 institutionsQ1 2022: 139 institutionsQ2 2022: 150 institutionsQ3 2022: 147 institutionsQ4 2022: 155 institutionsQ1 2023: 132 institutionsQ2 2023: 138 institutionsQ3 2023: 120 institutionsQ4 2023: 120 institutionsQ1 2024: 114 institutionsQ2 2024: 114 institutionsQ3 2024: 91 institutionsQ4 2024: 87 institutionsQ1 2025: 50 institutionsQ2 2025: 50 institutionsQ3 2025: 52 institutionsQ4 2025: 68 institutionsQ1 2026: 77 institutionsQ2 2026: 96 institutions
Value heldQ3 2024: $49.2M
Q1 2021: $637.1MQ2 2021: $608.7MQ3 2021: $334.4MQ4 2021: $347.5MQ1 2022: $501.8MQ2 2022: $302.8MQ3 2022: $364.1MQ4 2022: $334.4MQ1 2023: $340.1MQ2 2023: $145.0MQ3 2023: $102.8MQ4 2023: $63.5MQ1 2024: $113.0MQ2 2024: $58.6MQ3 2024: $49.2MQ4 2024: $41.2MQ1 2025: $13.7MQ2 2025: $19.0MQ3 2025: $19.5MQ4 2025: $69.6MQ1 2026: $98.4MQ2 2026: $206.8M
Institutions holding KPTI and their total value by quarter
QuarterHoldersValue
Q2 202696$206.8M
Q1 202677$98.4M
Q4 202568$69.6M
Q3 202552$19.5M
Q2 202550$19.0M
Q1 202550$13.7M
Q4 202487$41.2M
Q3 202491$49.2M
Q2 2024114$58.6M
Q1 2024114$113.0M
Q4 2023120$63.5M
Q3 2023120$102.8M
Q2 2023138$145.0M
Q1 2023132$340.1M
Q4 2022155$334.4M
Q3 2022147$364.1M
Q2 2022150$302.8M
Q1 2022139$501.8M
Q4 2021143$347.5M
Q3 2021134$334.4M
Q2 2021154$608.7M
Q1 2021171$637.1M

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Karyopharm Therapeutics Inc.; share changes are against Q2 2024.

Institutions holding KPTI in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Mirae Asset Global ETFs Holdings Ltd.0$00.00%−56,945−100.0%Sold out
Colony Group, LLC0$00.00%−45,930−100.0%Sold out
Simplicity Wealth,LLC0$00.00%−49,160−100.0%Sold out
Bleakley Financial Group, LLC0$00.00%−49,160−100.0%Sold out
SEI Investments Co0$00.00%−40,000−100.0%Sold out
Point72 (DIFC) Ltd0$00.00%−35,939−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−35,184−100.0%Sold out
Redwood Wealth Management Group, LLC0$00.00%−34,030−100.0%Sold out
Jump Financial, LLC0$00.00%−26,798−100.0%Sold out
Banque Cantonale Vaudoise0$00.00%−25,000−100.0%Sold out
Neuberger Berman Group LLC0$00.00%−22,951−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−22,562−100.0%Sold out
O'Shaughnessy Asset Management, LLC0$00.00%−21,941−100.0%Sold out
Rhumbline Advisers0$00.00%−16,431−100.0%Sold out
Paloma Partners Management Co0$00.00%−15,435−100.0%Sold out
ProShare Advisors LLC0$00.00%−15,170−100.0%Sold out
Scientech Research LLC0$00.00%−10,950−100.0%Sold out
CWM, LLC0$00.00%−6,248−100.0%Sold out
New York State Common Retirement Fund0$00.00%−955−100.0%Sold out
Providence Capital Advisors, LLC0$00.00%−312−100.0%Sold out
Kelly Financial Services LLC0$00.00%−250−100.0%Sold out
Nisa Investment Advisors, LLC0$00.00%−50−100.0%Sold out
BlackRock Inc.––––Not filed
JJJ Advisors Inc.––––Not filed