Karyopharm Therapeutics Inc.

KPTI

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001503802

SEC filings (opens in a new tab)

In the last 90 days, Karyopharm Therapeutics Inc. insiders filed 0 open-market purchases and 3 sales; 96 institutions reported holding it in 13F filings for Q2 2026, worth $206.8M in total; no superinvestor holds it.

Q3 2024 vs. Q2 2024

How the institutions holding Karyopharm Therapeutics Inc. changed between Q2 2024 and Q3 2024.

All holders in Q3 2024 All holders in Q2 2024

13F holders of KPTI: Q2 2024 compared with Q3 2024
Measure	Q2 2024	Of which not filed for Q3 2024	Q3 2024	Change
Holders	114	2	91	−21
Shares	67.6M	4.17M	59.4M	−3.98M (−6.3%)
Value	$58.6M	$3.62M	$49.2M	−$5.79M (−10.5%)

2 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so the changes leave them out.

New holders (10)

Institutions that held Karyopharm Therapeutics Inc. at the end of Q3 2024 but not at the end of Q2 2024.

Institutions new to KPTI in Q3 2024
Institution	Shares	Value	% of portfolio
BlackRock, Inc.	3,638,378	$3.02M	0.00%
Prudential Financial Inc	74,600	$61.9K	0.00%
Cerity Partners LLC	51,533	$42.8K	0.00%
Two Sigma Advisers, LP	31,200	$25.9K	0.00%
Monashee Investment Management LLC	132,435	$25.6K	0.00%
JustInvest LLC	17,188	$14.3K	0.00%
Wolverine Trading, LLC	13,735	$9.94K	0.00%
Avidian Wealth Solutions, LLC	10,100	$8.38K	0.00%
Golden State Equity Partners	1,800	$1.49K	0.00%
Lazard Asset Management LLC	1,570	$1.00K	0.00%

Sold out (31)

Institutions that held Karyopharm Therapeutics Inc. at the end of Q2 2024 and filed for Q3 2024 without it.

Institutions that sold out of KPTI in Q3 2024
Institution	Shares, Q2 2024	Value, Q2 2024
Opaleye Management Inc.	1,425,000	$1.24M
Superstring Capital Management LP	534,485	$463.7K
Y-Intercept (Hong Kong) Ltd	410,954	$356.5K
Los Angeles Capital Management LLC	354,020	$307.1K
Centiva Capital, LP	203,600	$176.6K
HRT Financial LP	147,536	$128.0K
State of Wyoming	82,685	$71.7K
Verition Fund Management LLC	68,932	$59.8K
Schonfeld Strategic Advisors LLC	57,600	$50.0K
Mirae Asset Global ETFs Holdings Ltd.	56,945	$49.4K
Colony Group, LLC	45,930	$44.0K
Simplicity Wealth,LLC	49,160	$42.7K
Bleakley Financial Group, LLC	49,160	$42.7K
SEI Investments Co	40,000	$34.7K
Point72 (DIFC) Ltd	35,939	$31.2K
Tower Research Capital LLC (TRC)	35,184	$30.5K
Redwood Wealth Management Group, LLC	34,030	$29.5K
Jump Financial, LLC	26,798	$23.3K
Banque Cantonale Vaudoise	25,000	$22.0K
Neuberger Berman Group LLC	22,951	$19.9K
Balyasny Asset Management LLC	22,562	$19.6K
O'Shaughnessy Asset Management, LLC	21,941	$19.0K
Rhumbline Advisers	16,431	$14.3K
Paloma Partners Management Co	15,435	$13.4K
ProShare Advisors LLC	15,170	$13.2K
Scientech Research LLC	10,950	$9.50K
CWM, LLC	6,248	$5.00K
New York State Common Retirement Fund	955	$829
Providence Capital Advisors, LLC	312	$271
Kelly Financial Services LLC	250	$217
Nisa Investment Advisors, LLC	50	$43

Not filed for Q3 2024 yet (2)

Institutions that held Karyopharm Therapeutics Inc. at the end of Q2 2024 and haven't filed a 13F for Q3 2024. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding KPTI in Q2 2024 that haven't filed for Q3 2024
Institution	Shares, Q2 2024	Value, Q2 2024
BlackRock Inc.	4,169,788	$3.62M
JJJ Advisors Inc.	17	$15