Karyopharm Therapeutics Inc.
KPTI- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
In the last 90 days, Karyopharm Therapeutics Inc. insiders filed 0 open-market purchases and 2 sales; 96 institutions reported holding it in 13F filings for Q2 2026, worth $206.8M in total; no superinvestor holds it.
13F holders, Q2 2023
Institutional positions in Karyopharm Therapeutics Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 138
- +6 vs. Q1 2023
- Shares held
- 81.5M
- −5.97M (−6.8%) vs. Q1 2023
- Total value
- $145.0M
- −$195.1M (−57.4%) vs. Q1 2023
- New holders
- 30
- 43 more added
- Sold out
- 24
- 42 more reduced
Compare with Q1 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KPTI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 96 | $206.8M |
| Q1 2026 | 77 | $98.4M |
| Q4 2025 | 68 | $69.6M |
| Q3 2025 | 52 | $19.5M |
| Q2 2025 | 50 | $19.0M |
| Q1 2025 | 50 | $13.7M |
| Q4 2024 | 87 | $41.2M |
| Q3 2024 | 91 | $49.2M |
| Q2 2024 | 114 | $58.6M |
| Q1 2024 | 114 | $113.0M |
| Q4 2023 | 120 | $63.5M |
| Q3 2023 | 120 | $102.8M |
| Q2 2023 | 138 | $145.0M |
| Q1 2023 | 132 | $340.1M |
| Q4 2022 | 155 | $334.4M |
| Q3 2022 | 147 | $364.1M |
| Q2 2022 | 150 | $302.8M |
| Q1 2022 | 139 | $501.8M |
| Q4 2021 | 143 | $347.5M |
| Q3 2021 | 134 | $334.4M |
| Q2 2021 | 154 | $608.7M |
| Q1 2021 | 171 | $637.1M |
Institutions, Q2 2023
Shares, value and share of portfolio for each institution holding Karyopharm Therapeutics Inc.; share changes are against Q1 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Dynamic Technology Lab Private Ltd | 18,799 | $34.0K | 0.00% | +18,799 | New |
| New York State Common Retirement Fund | 18,959 | $33.9K | 0.00% | −115−0.6% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 18,134 | $32.5K | 0.00% | +9,813+117.9% | Added |
| Tower Research Capital LLC (TRC) | 17,466 | $31.3K | 0.00% | −1,877−9.7% | Reduced |
| Snowden Capital Advisors LLC | 16,200 | $29.0K | 0.00% | 00.0% | Unchanged |
| Sawtooth Solutions, LLC | 15,966 | $28.6K | 0.00% | +15,966 | New |
| Bleakley Financial Group, LLC | 15,966 | $28.6K | 0.00% | +15,966 | New |
| Prelude Capital Management, LLC | 15,933 | $28.5K | 0.00% | −26,494−62.4% | Reduced |
| Amalgamated Bank | 15,431 | $28.0K | 0.00% | +4,860+46.0% | Added |
| SG Americas Securities, LLC | 14,868 | $27.0K | 0.00% | −20,996−58.5% | Reduced |
| Banque Cantonale Vaudoise | 15,000 | $27.0K | 0.00% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 13,925 | $24.9K | 0.00% | +13,925 | New |
| Baird Financial Group, Inc. | 13,800 | $24.7K | 0.00% | −13,175−48.8% | Reduced |
| Two Sigma Securities, LLC | 13,480 | $24.1K | 0.00% | +13,480 | New |
| ELCO Management Co., LLC | 13,474 | $24.1K | 0.02% | +13,474 | New |
| HSBC Holdings PLC | 12,279 | $22.3K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 11,600 | $20.8K | 0.00% | 00.0% | Unchanged |
| Victory Capital Management Inc | 11,418 | $20.4K | 0.00% | −266−2.3% | Reduced |
| Janney Montgomery Scott LLC | 10,000 | $18.0K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 7,079 | $12.5K | 0.00% | −1,827−20.5% | Reduced |
| Metropolitan Life Insurance Co | 6,242 | $11.2K | 0.00% | +1,972+46.2% | Added |
| Ameritas Investment Partners, Inc. | 6,194 | $11.1K | 0.00% | 00.0% | Unchanged |
| PEAK6 Investments LLC | 4,552 | $8.15K | 0.00% | −10,448−69.7% | Reduced |
| The PNC Financial Services Group, Inc. | 3,000 | $5.37K | 0.00% | 00.0% | Unchanged |
| Founders Capital Management | 2,000 | $3.58K | 0.00% | 00.0% | Unchanged |
| MB, Levis & Associates, LLC | 1,500 | $2.69K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 1,494 | $2.67K | 0.00% | −42−2.7% | Reduced |
| Group One Trading, L.P. | 1,493 | $2.67K | 0.00% | −1,617−52.0% | Reduced |
| Harbour Investments, Inc. | 1,300 | $2.33K | 0.00% | +500+62.5% | Added |
| TD Waterhouse Canada Inc. | 1,060 | $1.90K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 800 | $1.43K | 0.00% | −60−7.0% | Reduced |
| AdvisorNet Financial, Inc | 700 | $1.25K | 0.00% | 00.0% | Unchanged |
| Lazard Asset Management LLC | 1,000 | $1.00K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 500 | $895 | 0.00% | 00.0% | Unchanged |
| Kelly Financial Services LLC | 250 | $448 | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 104 | $186 | 0.00% | +104 | New |
| Daiwa Securities Group Inc. | 138 | $0 | 0.00% | 00.0% | Unchanged |
| Sofos Investments, Inc. | 2 | – | – | −2−50.0% | Reduced |
| Proequities, Inc. | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Rafferty Asset Management, LLC | 0 | $0 | 0.00% | −913,301−100.0% | Sold out |
| Affinity Asset Advisors, LLC | 0 | $0 | 0.00% | −460,979−100.0% | Sold out |
| Caxton Associates LP | 0 | $0 | 0.00% | −235,626−100.0% | Sold out |
| State of Wisconsin Investment Board | 0 | $0 | 0.00% | −197,433−100.0% | Sold out |
| Profund Advisors LLC | 0 | $0 | 0.00% | −167,517−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −151,235−100.0% | Sold out |
| Hennion & Walsh Asset Management, Inc. | 0 | $0 | 0.00% | −139,574−100.0% | Sold out |
| Los Angeles Capital Management LLC | 0 | $0 | 0.00% | −113,724−100.0% | Sold out |
| Algert Global LLC | 0 | $0 | 0.00% | −86,813−100.0% | Sold out |
| Fred Alger Management, LLC | 0 | $0 | 0.00% | −69,420−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −56,700−100.0% | Sold out |
| E Fund Management Co., Ltd. | 0 | $0 | 0.00% | −51,849−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | – | Sold out |
| Mirae Asset Global Investments Co., Ltd. | 0 | $0 | 0.00% | −37,398−100.0% | Sold out |
| Allspring Global Investments Holdings, LLC | 0 | $0 | 0.00% | −24,593−100.0% | Sold out |
| Ashton Thomas Private Wealth, LLC | 0 | $0 | 0.00% | −16,000−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −12,553−100.0% | Sold out |
| Moors & Cabot, Inc. | 0 | $0 | 0.00% | −12,200−100.0% | Sold out |
| Bayesian Capital Management, LP | 0 | $0 | 0.00% | −11,880−100.0% | Sold out |
| Belpointe Asset Management LLC | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −600−100.0% | Sold out |
| Lindbrook Capital, LLC | 0 | $0 | 0.00% | −399−100.0% | Sold out |
| Quent Capital, LLC | 0 | $0 | 0.00% | −386−100.0% | Sold out |