Karyopharm Therapeutics Inc.
KPTI- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
In the last 90 days, Karyopharm Therapeutics Inc. insiders filed 0 open-market purchases and 3 sales; 96 institutions reported holding it in 13F filings for Q2 2026, worth $206.8M in total; no superinvestor holds it.
13F holders, Q2 2022
Institutional positions in Karyopharm Therapeutics Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 150
- +16 vs. Q1 2022
- Shares held
- 67.1M
- −737.9K (−1.1%) vs. Q1 2022
- Total value
- $302.8M
- −$195.8M (−39.3%) vs. Q1 2022
- New holders
- 28
- 40 more added
- Sold out
- 12
- 58 more reduced
5 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KPTI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 96 | $206.8M |
| Q1 2026 | 77 | $98.4M |
| Q4 2025 | 68 | $69.6M |
| Q3 2025 | 52 | $19.5M |
| Q2 2025 | 50 | $19.0M |
| Q1 2025 | 50 | $13.7M |
| Q4 2024 | 87 | $41.2M |
| Q3 2024 | 91 | $49.2M |
| Q2 2024 | 114 | $58.6M |
| Q1 2024 | 114 | $113.0M |
| Q4 2023 | 120 | $63.5M |
| Q3 2023 | 120 | $102.8M |
| Q2 2023 | 138 | $145.0M |
| Q1 2023 | 132 | $340.1M |
| Q4 2022 | 155 | $334.4M |
| Q3 2022 | 147 | $364.1M |
| Q2 2022 | 150 | $302.8M |
| Q1 2022 | 139 | $501.8M |
| Q4 2021 | 143 | $347.5M |
| Q3 2021 | 134 | $334.4M |
| Q2 2021 | 154 | $608.7M |
| Q1 2021 | 171 | $637.1M |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Karyopharm Therapeutics Inc.; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baird Financial Group, Inc. | 16,923 | $76.0K | 0.00% | −114−0.7% | Reduced |
| Aquatic Capital Management LLC | 16,100 | $73.0K | 0.02% | +16,100 | New |
| ProShare Advisors LLC | 14,744 | $66.0K | 0.00% | −6,555−30.8% | Reduced |
| Royal Bank of Canada | 13,321 | $59.0K | 0.00% | −3,246−19.6% | Reduced |
| Virtu Financial LLC | 13,137 | $59.0K | 0.01% | +13,137 | New |
| Commonwealth Equity Services, LLC | 12,990 | $58.0K | 0.00% | −100−0.8% | Reduced |
| First Republic Investment Management, Inc. | 12,341 | $56.0K | 0.00% | −492−3.8% | Reduced |
| Janus Henderson Group PLC | 12,220 | $55.0K | 0.00% | +57+0.5% | Added |
| Snowden Capital Advisors LLC | 12,200 | $55.0K | 0.00% | −93−0.8% | Reduced |
| Quantbot Technologies LP | 12,053 | $54.0K | 0.00% | −41,247−77.4% | Reduced |
| American Trust | 11,922 | $54.0K | 0.00% | −466−3.8% | Reduced |
| Mackenzie Financial Corp | 11,922 | $54.0K | 0.00% | +11,922 | New |
| Jump Financial, LLC | 12,140 | $54.0K | 0.00% | +12,140 | New |
| Amalgamated Bank | 11,818 | $53.0K | 0.00% | +96+0.8% | Added |
| Prelude Capital Management, LLC | 11,793 | $53.0K | 0.00% | +11,793 | New |
| Creative Planning | 11,600 | $52.0K | 0.00% | −1,500−11.5% | Reduced |
| Teacher Retirement System of Texas | 10,857 | $49.0K | 0.00% | −3,120−22.3% | Reduced |
| State of Wyoming | 10,606 | $48.0K | 0.03% | −4,510−29.8% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 10,390 | $47.0K | 0.00% | −251−2.4% | Reduced |
| PDT Partners, LLC | 10,234 | $46.0K | 0.00% | −20,544−66.7% | Reduced |
| Running Point Capital Advisors, LLC | 10,000 | $45.0K | 0.03% | 00.0% | Unchanged |
| Wells Fargo & Company | 6,851 | $31.0K | 0.00% | −34,025−83.2% | Reduced |
| Simplex Trading, LLC | 6,871 | $30.0K | 0.00% | +6,871 | New |
| Ameritas Investment Partners, Inc. | 6,194 | $27.0K | 0.00% | 00.0% | Unchanged |
| Banque Cantonale Vaudoise | 5,000 | $23.0K | 0.00% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 4,941 | $22.0K | 0.00% | +4,941 | New |
| Advisor Group Holdings, Inc. | 3,644 | $16.0K | 0.00% | +2+0.1% | Added |
| The PNC Financial Services Group, Inc. | 3,000 | $14.0K | 0.00% | −800−21.1% | Reduced |
| Great West Life Assurance Co | 3,017 | $14.0K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 2,658 | $12.0K | 0.00% | −2,154−44.8% | Reduced |
| Founders Capital Management | 2,000 | $9.00K | 0.01% | −1,000−33.3% | Reduced |
| PEAK6 Investments LLC | 4,552 | $8.15K | 0.00% | +4,552 | New |
| US Bancorp | 1,426 | $7.00K | 0.00% | −1,803−55.8% | Reduced |
| TD Waterhouse Canada Inc. | 1,060 | $5.00K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 1,000 | $5.00K | 0.00% | 00.0% | Unchanged |
| Cutler Group LP | 1,219 | $5.00K | 0.00% | +1,219 | New |
| Lazard Asset Management LLC | 1,000 | $4.00K | 0.00% | −23,729−96.0% | Reduced |
| Rockefeller Capital Management L.P. | 900 | $4.00K | 0.00% | −2,500−73.5% | Reduced |
| Money Concepts Capital Corp | 800 | $4.00K | 0.00% | −70−8.0% | Reduced |
| Nisa Investment Advisors, LLC | 800 | $4.00K | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 800 | $4.00K | 0.00% | +800 | New |
| AdvisorNet Financial, Inc | 700 | $3.00K | 0.00% | 00.0% | Unchanged |
| Kelly Financial Services LLC | 250 | $1.13K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 199 | $1.00K | 0.00% | −877−81.5% | Reduced |
| Daiwa Securities Group Inc. | 138 | $1.00K | 0.00% | 00.0% | Unchanged |
| Lindbrook Capital, LLC | 235 | $1.00K | 0.00% | +235 | New |
| Allworth Financial LP | 100 | $0 | 0.00% | 00.0% | Unchanged |
| Quadrant Capital Group LLC | 90 | $0 | 0.00% | 00.0% | Unchanged |
| Ellevest, Inc. | 20 | $0 | 0.00% | −7−25.9% | Reduced |
| Quent Capital, LLC | 30 | $0 | 0.00% | 00.0% | Unchanged |
| Victory Capital Management Inc | 0 | $0 | 0.00% | −197,570−100.0% | Sold out |
| ClariVest Asset Management LLC | 0 | $0 | 0.00% | −59,600−100.0% | Sold out |
| Capital Fund Management S.A. | 0 | $0 | 0.00% | −44,154−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −26,482−100.0% | Sold out |
| Dimensional Fund Advisors LP | 0 | $0 | 0.00% | −23,570−100.0% | Sold out |
| Blueshift Asset Management, LLC | 0 | $0 | 0.00% | −22,229−100.0% | Sold out |
| BIT Capital GmbH | 0 | $0 | 0.00% | −13,000−100.0% | Sold out |
| Future Financial Wealth Managment LLC | 0 | $0 | 0.00% | −900−100.0% | Sold out |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −830−100.0% | Sold out |
| Jefferies Group LLC | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| American Portfolios Advisors | 0 | $0 | 0.00% | −83−100.0% | Sold out |
| Aaron Wealth Advisors | 0 | $0 | 0.00% | −2,837−100.0% | Sold out |
| Parametric Portfolio Associates LLC | – | – | – | – | Not filed |
| Susquehanna Fundamental Investments, LLC | – | – | – | – | Not filed |
| IndexIQ Advisors LLC | – | – | – | – | Not filed |
| Golden State Equity Partners | – | – | – | – | Not filed |
| Amalgamated Financial Corp. | – | – | – | – | Not filed |