Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 354
- +1 vs. Q2 2024
- Shares held
- 157.5M
- +24.6M (+18.5%) vs. Q2 2024
- Total value
- $6.31B
- −$23.0M (−0.4%) vs. Q2 2024
- New holders
- 53
- 131 more added
- Sold out
- 52
- 107 more reduced
4 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| O'Shaughnessy Asset Management, LLC | 5,273 | $203.7K | 0.00% | +5,273 | New |
| Mirae Asset Global Investments Co., Ltd. | 5,288 | $216.0K | 0.00% | +930+21.3% | Added |
| Harbor Advisors LLC | 5,500 | $220.3K | 0.04% | +5,500 | New |
| Vontobel Holding Ltd. | 5,502 | $220.4K | 0.00% | −2,483−31.1% | Reduced |
| HighTower Advisors, LLC | 5,559 | $223.0K | 0.00% | −75−1.3% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 5,585 | $223.7K | 0.00% | −489−8.1% | Reduced |
| Colony Group, LLC | 5,696 | $228.2K | 0.00% | +5,696 | New |
| US Bancorp | 5,730 | $229.5K | 0.00% | −5,320−48.1% | Reduced |
| Advisors Asset Management, Inc. | 6,140 | $246.0K | 0.00% | +1,066+21.0% | Added |
| Gotham Asset Management, LLC | 6,262 | $250.9K | 0.00% | 00.0% | Unchanged |
| American Century Companies Inc | 6,293 | $252.1K | 0.00% | −7,148−53.2% | Reduced |
| Acadian Asset Management LLC | 6,328 | $253.0K | 0.00% | +6,328 | New |
| Castle Rock Wealth Management, LLC | 6,972 | $264.0K | 0.06% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 6,724 | $274.7K | 0.00% | +3,323+97.7% | Added |
| Simplex Trading, LLC | 6,944 | $278.0K | 0.01% | −56,403−89.0% | Reduced |
| Truist Financial Corp | 7,348 | $294.4K | 0.00% | −655−8.2% | Reduced |
| SG Americas Securities, LLC | 7,419 | $297.0K | 0.00% | +7,419 | New |
| Comerica Bank | 7,615 | $305.0K | 0.00% | −13,809−64.5% | Reduced |
| Sanctuary Advisors, LLC | 9,277 | $315.5K | 0.00% | −7,164−43.6% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 7,825 | $319.7K | 0.00% | +1,468+23.1% | Added |
| Virtus ETF Advisers LLC | 8,009 | $320.8K | 0.15% | 00.0% | Unchanged |
| Maryland State Retirement & Pension System | 8,284 | $331.9K | 0.01% | −2,666−24.3% | Reduced |
| Clearstead Advisors, LLC | 8,285 | $331.9K | 0.01% | 00.0% | Unchanged |
| Utah Retirement Systems | 8,400 | $336.5K | 0.00% | +500+6.3% | Added |
| JustInvest LLC | 8,404 | $336.6K | 0.01% | +780+10.2% | Added |
| ProShare Advisors LLC | 8,640 | $346.1K | 0.00% | −371−4.1% | Reduced |
| Ariadne Wealth Management, LP | 9,147 | $351.8K | 0.19% | +9,147 | New |
| M&T Bank Corp | 8,896 | $356.6K | 0.00% | +70+0.8% | Added |
| Two Sigma Securities, LLC | 8,940 | $358.1K | 0.03% | −71,258−88.9% | Reduced |
| MetLife Investment Management | 9,363 | $375.1K | 0.00% | +514+5.8% | Added |
| Sectoral Asset Management Inc | 9,440 | $378.2K | 0.22% | −220−2.3% | Reduced |
| Fifth Third Bancorp | 9,572 | $383.5K | 0.00% | +110+1.2% | Added |
| Wiley Bros.-Aintree Capital, LLC | 9,606 | $384.8K | 0.01% | +9,606 | New |
| Cambridge Investment Research Advisors, Inc. | 9,738 | $390.0K | 0.00% | −310−3.1% | Reduced |
| Franklin Resources Inc | 10,155 | $392.3K | 0.00% | +133+1.3% | Added |
| The PNC Financial Services Group, Inc. | 9,893 | $396.3K | 0.00% | +532+5.7% | Added |
| Annis Gardner Whiting Capital Advisors, LLC | 9,936 | $398.0K | 0.11% | +540+5.7% | Added |
| Amalgamated Bank | 9,957 | $399.0K | 0.00% | +300+3.1% | Added |
| Cypress Capital, LLC | 10,000 | $400.6K | 0.10% | 00.0% | Unchanged |
| Advent Capital Management | 10,000 | $400.6K | 0.01% | +10,000 | New |
| Troluce Capital Advisors LLC | 10,000 | $400.6K | 0.07% | +10,000 | New |
| Teza Capital Management LLC | 10,600 | $424.6K | 0.05% | −14,559−57.9% | Reduced |
| Suvretta Capital Management, LLC | 10,800 | $432.6K | 0.02% | 00.0% | Unchanged |
| Susquehanna Portfolio Strategies, LLC | 10,894 | $436.4K | 0.03% | −32,134−74.7% | Reduced |
| Midwest Professional Planners, LTD. | 11,106 | $444.9K | 0.14% | +966+9.5% | Added |
| Bridgefront Capital, LLC | 11,196 | $448.5K | 0.17% | +5,637+101.4% | Added |
| Canada Pension Plan Investment Board | 11,200 | $448.7K | 0.00% | +11,200 | New |
| Northwestern Mutual Wealth Management Co | 11,263 | $451.2K | 0.00% | +50+0.4% | Added |
| Janney Montgomery Scott LLC | 11,294 | $452.0K | 0.00% | −6,240−35.6% | Reduced |
| Plancorp, LLC | 11,286 | $452.1K | 0.02% | 00.0% | Unchanged |
| Aigen Investment Management, LP | 11,612 | $465.2K | 0.09% | +11,612 | New |
| Wolverine Trading, LLC | 11,611 | $474.3K | 0.01% | −9,717−45.6% | Reduced |
| Horizon Kinetics Asset Management LLC | 11,952 | $478.8K | 0.01% | −524−4.2% | Reduced |
| SpiderRock Advisors, LLC | 12,036 | $482.2K | 0.01% | +10+0.1% | Added |
| Twin Tree Management, LP | 12,428 | $497.9K | 0.01% | +2,047+19.7% | Added |
| Brown Advisory Inc | 12,746 | $510.6K | 0.00% | +1,780+16.2% | Added |
| E Fund Management Co., Ltd. | 12,752 | $510.8K | 0.03% | +2,497+24.3% | Added |
| Stratos Wealth Partners, LTD. | 12,788 | $512.3K | 0.01% | −30.0% | Reduced |
| Martingale Asset Management L P | 12,809 | $513.1K | 0.01% | +40.0% | Added |
| Principal Financial Group Inc | 13,112 | $525.3K | 0.00% | −4,346−24.9% | Reduced |
| Assenagon Asset Management S.A. | 13,298 | $532.7K | 0.00% | −10,928−45.1% | Reduced |
| PDT Partners, LLC | 13,400 | $536.8K | 0.05% | −30−0.2% | Reduced |
| Westmount Partners, LLC | 13,462 | $539.3K | 0.16% | 00.0% | Unchanged |
| PEAK6 Investments LLC | 13,500 | $540.8K | 0.03% | −1,501−10.0% | Reduced |
| North Star Asset Management Inc | 13,640 | $546.4K | 0.02% | 00.0% | Unchanged |
| Chartwell Investment Partners, LLC | 13,759 | $551.0K | 0.02% | 00.0% | Unchanged |
| Tanaka Capital Management Inc | 14,512 | $581.0K | 1.34% | 00.0% | Unchanged |
| Raymond James Financial Services Advisors, Inc. | 14,570 | $583.7K | 0.00% | −765−5.0% | Reduced |
| Public Employees Retirement Association of Colorado | 15,589 | $624.0K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 16,372 | $655.7K | 0.00% | +1,680+11.4% | Added |
| Bleakley Financial Group, LLC | 16,678 | $668.1K | 0.02% | +338+2.1% | Added |
| XTX Topco Ltd | 16,805 | $673.2K | 0.05% | +16,805 | New |
| NBT Bank N A | 17,050 | $683.0K | 0.05% | 00.0% | Unchanged |
| Capula Management Ltd | 17,365 | $695.6K | 0.01% | +17,365 | New |
| Seven Eight Capital, LP | 17,394 | $696.8K | 0.06% | +17,394 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 17,741 | $710.7K | 0.00% | −26,515−59.9% | Reduced |
| Victory Capital Management Inc | 18,350 | $735.1K | 0.00% | +1,020+5.9% | Added |
| Toroso Investments, LLC | 18,908 | $757.5K | 0.01% | −42−0.2% | Reduced |
| Xponance, Inc. | 19,021 | $762.0K | 0.01% | +906+5.0% | Added |
| Monashee Investment Management LLC | 20,000 | $801.2K | 0.09% | +20,000 | New |
| Y-Intercept (Hong Kong) Ltd | 20,141 | $806.8K | 0.05% | +20,141 | New |
| Nicollet Investment Management, Inc. | 20,402 | $817.0K | 0.28% | +294+1.5% | Added |
| Natixis Advisors, L.P. | 21,080 | $844.0K | 0.00% | −2,324−9.9% | Reduced |
| Commonwealth Equity Services, LLC | 21,453 | $859.0K | 0.00% | −1,216−5.4% | Reduced |
| Raymond James & Associates | 22,524 | $902.3K | 0.00% | −1,049−4.5% | Reduced |
| Lazard Asset Management LLC | 22,923 | $917.0K | 0.00% | +13,408+140.9% | Added |
| Mariner, LLC | 23,127 | $927.6K | 0.00% | +1,273+5.8% | Added |
| Castle Hook Partners LP | 23,940 | $959.0K | 0.03% | +23,940 | New |
| Teachers Retirement System of the State of Kentucky | 24,083 | $965.0K | 0.01% | 00.0% | Unchanged |
| Landscape Capital Management, L.L.C. | 25,435 | $1.02M | 0.10% | +25,435 | New |
| Caption Management, LLC | 26,600 | $1.07M | 0.11% | −133,400−83.4% | Reduced |
| Pathstone Holdings, LLC | 27,807 | $1.11M | 0.00% | +5,102+22.5% | Added |
| China Universal Asset Management Co., Ltd. | 28,121 | $1.13M | 0.12% | +10,971+64.0% | Added |
| Creative Planning | 28,382 | $1.14M | 0.00% | +1,522+5.7% | Added |
| Brevan Howard Capital Management LP | 28,479 | $1.14M | 0.05% | +6,632+30.4% | Added |
| Artia Global Partners LP | 30,479 | $1.22M | 0.35% | −32,000−51.2% | Reduced |
| Capital Fund Management S.A. | 30,691 | $1.23M | 0.01% | +30,691 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 30,922 | $1.24M | 0.00% | −233−0.7% | Reduced |
| Grandfield & Dodd, LLC | 34,813 | $1.39M | 0.08% | +760+2.2% | Added |
| Polar Asset Management Partners Inc. | 35,400 | $1.42M | 0.03% | +35,400 | New |