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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q2 2024

Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
357
−1 vs. Q1 2024
Shares held
143.3M
+1.29M (+0.9%) vs. Q1 2024
Total value
$6.83B
+$666.0M (+10.8%) vs. Q1 2024
New holders
52
120 more added
Sold out
53
132 more reduced

3 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 357 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ2 2024: $6.83B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2024.

Institutions holding IONS in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Mitchell & Pahl Private Wealth, LLC4,540$216.4K0.11%+4,540New
Point72 (DIFC) Ltd4,694$223.7K0.02%−23,797−83.5%Reduced
Farallon Capital Management, L.L.C.4,800$228.8K0.00%−729,200−99.3%Reduced
Kestra Advisory Services, LLC5,491$236.2K0.00%−59−1.1%Reduced
Beaird Harris Wealth Management, LLC5,000$238.3K0.02%00.0%Unchanged
Advisors Asset Management, Inc.5,074$241.8K0.00%+1,896+59.7%Added
Stephens Inc5,138$244.9K0.00%−2,715−34.6%Reduced
Buckingham Strategic Wealth, LLC5,251$250.3K0.00%00.0%Unchanged
HSBC Holdings PLC5,326$252.2K0.00%+5,326New
Fox Run Management, L.L.C.5,421$258.4K0.05%+5,421New
Bridgefront Capital, LLC5,559$264.9K0.11%+5,559New
Perkins Capital Management Inc5,550$265.0K0.25%00.0%Unchanged
Readystate Asset Management LP5,600$266.9K0.01%+5,600New
HighTower Advisors, LLC5,634$271.0K0.00%+549+10.8%Added
Oppenheimer Asset Management Inc.5,777$275.3K0.00%−4,049−41.2%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.6,074$289.5K0.00%+2,232+58.1%Added
Jump Financial, LLC6,184$294.7K0.01%−9,509−60.6%Reduced
Pearl River Capital, LLC6,187$294.9K0.05%−19,772−76.2%Reduced
Gotham Asset Management, LLC6,262$298.4K0.00%−524−7.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.6,357$300.2K0.00%+6,357New
Castle Rock Wealth Management, LLC6,972$328.5K0.08%00.0%Unchanged
JustInvest LLC7,624$363.3K0.01%+261+3.5%Added
Utah Retirement Systems7,900$376.5K0.00%00.0%Unchanged
Vontobel Holding Ltd.7,985$380.6K0.00%+488+6.5%Added
Truist Financial Corp8,003$381.4K0.00%−1,496−15.7%Reduced
Virtus ETF Advisers LLC8,009$381.7K0.19%+361+4.7%Added
Gsa Capital Partners LLP8,231$392.0K0.03%−94−1.1%Reduced
Clearstead Advisors, LLC8,285$394.9K0.01%+7,790+1,573.7%Added
Ameriprise Financial Inc8,792$419.0K0.00%−6,881−43.9%Reduced
M&T Bank Corp8,826$420.8K0.00%+2,978+50.9%Added
MetLife Investment Management8,849$421.7K0.00%+1,008+12.9%Added
ProShare Advisors LLC9,011$429.5K0.00%−1,205−11.8%Reduced
Deutsche Bank AG9,096$433.5K0.00%+508+5.9%Added
The PNC Financial Services Group, Inc.9,361$446.1K0.00%+542+6.1%Added
Annis Gardner Whiting Capital Advisors, LLC9,396$447.8K0.13%+9,396New
Fifth Third Bancorp9,462$451.0K0.00%−171−1.8%Reduced
Lazard Asset Management LLC9,515$452.0K0.00%+1,660+21.1%Added
Amalgamated Bank9,657$460.0K0.00%+454+4.9%Added
Sectoral Asset Management Inc9,660$460.4K0.19%−440−4.4%Reduced
International Assets Investment Management, LLC9,707$462.6K0.04%+2,100+27.6%Added
Cypress Capital, LLC10,000$476.6K0.13%00.0%Unchanged
Franklin Resources Inc10,022$477.6K0.00%+213+2.2%Added
Cambridge Investment Research Advisors, Inc.10,048$479.0K0.00%+736+7.9%Added
Midwest Professional Planners, LTD.10,140$483.3K0.16%+424+4.4%Added
E Fund Management Co., Ltd.10,255$488.8K0.03%+430+4.4%Added
Twin Tree Management, LP10,381$494.8K0.01%+2,818+37.3%Added
Suvretta Capital Management, LLC10,800$514.7K0.02%00.0%Unchanged
Lisanti Capital Growth, LLC10,845$516.9K0.12%−16,990−61.0%Reduced
Maryland State Retirement & Pension System10,950$521.9K0.01%00.0%Unchanged
Brown Advisory Inc10,966$522.6K0.00%−156−1.4%Reduced
US Bancorp11,050$526.6K0.00%−877−7.4%Reduced
Northwestern Mutual Wealth Management Co11,213$534.4K0.00%+67+0.6%Added
Plancorp, LLC11,286$537.9K0.02%+131+1.2%Added
SpiderRock Advisors, LLC12,026$573.2K0.02%+12,026New
Parallax Volatility Advisers, L.P.12,310$586.7K0.01%+12,310New
Horizon Kinetics Asset Management LLC12,476$594.6K0.01%00.0%Unchanged
Stratos Wealth Partners, LTD.12,791$609.6K0.01%+12,791New
Martingale Asset Management L P12,805$610.3K0.01%−510−3.8%Reduced
Tudor Investment Corp Et Al13,098$624.3K0.01%+13,098New
Westmount Partners, LLC13,462$634.2K0.21%−410−3.0%Reduced
PDT Partners, LLC13,430$640.1K0.06%+13,430New
American Century Companies Inc13,441$640.6K0.00%+63+0.5%Added
North Star Asset Management Inc13,640$650.1K0.03%00.0%Unchanged
Chartwell Investment Partners, LLC13,759$656.0K0.02%+2,003+17.0%Added
Neuberger Berman Group LLC14,312$682.1K0.00%+78+0.5%Added
Sanctuary Advisors, LLC16,441$683.8K0.00%+16,441New
Tanaka Capital Management Inc14,512$692.0K1.64%−100−0.7%Reduced
Advisor Group Holdings, Inc.14,692$700.0K0.00%+66+0.5%Added
PEAK6 Investments LLC15,001$714.9K0.03%+4,001+36.4%Added
Raymond James Financial Services Advisors, Inc.15,335$730.9K0.00%+1,827+13.5%Added
Public Employees Retirement Association of Colorado15,589$743.0K0.00%−985−5.9%Reduced
Prudential Financial Inc15,717$749.1K0.00%+15,717New
First Trust Advisors LP16,194$771.8K0.00%−159,664−90.8%Reduced
Eisler Capital (US) LLC16,270$775.4K0.15%+16,270New
Engineers Gate Manager LP16,320$777.8K0.02%−22,272−57.7%Reduced
Simplicity Wealth,LLC16,340$778.8K0.02%+111+0.7%Added
Bleakley Financial Group, LLC16,340$778.8K0.02%+111+0.7%Added
NBT Bank N A17,050$812.6K0.06%00.0%Unchanged
China Universal Asset Management Co., Ltd.17,150$817.4K0.12%−10,877−38.8%Reduced
Inceptionr LLC17,289$824.0K0.23%+17,289New
Victory Capital Management Inc17,330$825.9K0.00%−307−1.7%Reduced
Principal Financial Group Inc17,458$832.0K0.00%−12,366−41.5%Reduced
J. Goldman & Co LP17,502$834.1K0.03%−213,922−92.4%Reduced
Janney Montgomery Scott LLC17,534$836.0K0.00%−9,359−34.8%Reduced
Xponance, Inc.18,115$863.4K0.01%+1,906+11.8%Added
Toroso Investments, LLC18,950$903.2K0.01%−1,455−7.1%Reduced
Nicollet Investment Management, Inc.20,108$958.0K0.36%−413−2.0%Reduced
Wolverine Trading, LLC21,328$1.02M0.02%+9,281+77.0%Added
Comerica Bank21,424$1.02M0.00%−18,067−45.7%Reduced
Brevan Howard Capital Management LP21,847$1.04M0.07%+16,923+343.7%Added
Mariner, LLC21,854$1.04M0.00%+1,070+5.1%Added
Commonwealth Equity Services, LLC22,669$1.08M0.00%+695+3.2%Added
Pathstone Holdings, LLC22,705$1.08M0.00%+1,452+6.8%Added
DCF Advisers, LLC23,000$1.10M0.57%+23,000New
Natixis Advisors, L.P.23,404$1.11M0.00%+376+1.6%Added
Raymond James & Associates23,573$1.12M0.00%−88,981−79.1%Reduced
Teachers Retirement System of the State of Kentucky24,083$1.15M0.01%00.0%Unchanged
Assenagon Asset Management S.A.24,226$1.15M0.00%−247,037−91.1%Reduced
Teza Capital Management LLC25,159$1.20M0.15%−4,777−16.0%Reduced
Blair William & Co25,262$1.20M0.00%−2,576−9.3%Reduced