Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 361
- −2 vs. Q4 2023
- Shares held
- 142.2M
- −349.1K (−0.2%) vs. Q4 2023
- Total value
- $6.17B
- −$1.04B (−14.4%) vs. Q4 2023
- New holders
- 49
- 124 more added
- Sold out
- 51
- 127 more reduced
2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Zurcher Kantonalbank (Zurich Cantonalbank) | 28,144 | $1.22M | 0.00% | −1,296−4.4% | Reduced |
| Point72 (DIFC) Ltd | 28,491 | $1.24M | 0.10% | +28,491 | New |
| Teacher Retirement System of Texas | 28,736 | $1.25M | 0.01% | −1,108−3.7% | Reduced |
| Principal Financial Group Inc | 29,824 | $1.29M | 0.00% | −1,315−4.2% | Reduced |
| Teza Capital Management LLC | 29,936 | $1.30M | 0.17% | +20,203+207.6% | Added |
| STRS Ohio | 29,965 | $1.30M | 0.01% | +5,186+20.9% | Added |
| Algert Global LLC | 30,242 | $1.31M | 0.05% | +12,830+73.7% | Added |
| Lighthouse Investment Partners, LLC | 30,379 | $1.32M | 0.08% | +30,379 | New |
| Graham Capital Management, L.P. | 30,541 | $1.32M | 0.04% | +18,016+143.8% | Added |
| Profund Advisors LLC | 31,570 | $1.37M | 0.05% | +2,497+8.6% | Added |
| Grandfield & Dodd, LLC | 33,774 | $1.46M | 0.09% | +670+2.0% | Added |
| Handelsbanken Fonder AB | 33,911 | $1.47M | 0.01% | +6,900+25.5% | Added |
| Arizona State Retirement System | 35,487 | $1.54M | 0.01% | −572−1.6% | Reduced |
| Guggenheim Capital LLC | 35,850 | $1.55M | 0.01% | +2,699+8.1% | Added |
| NEOS Investment Management LLC | 37,303 | $1.62M | 0.10% | +28,397+318.9% | Added |
| Nicholas Investment Partners, LP | 38,186 | $1.66M | 0.17% | +7,741+25.4% | Added |
| Engineers Gate Manager LP | 38,592 | $1.67M | 0.04% | +9,715+33.6% | Added |
| Comerica Bank | 39,491 | $1.71M | 0.01% | −123−0.3% | Reduced |
| Capital Counsel LLC | 39,580 | $1.72M | 0.08% | −500−1.2% | Reduced |
| Great West Life Assurance Co | 41,880 | $1.82M | 0.00% | +1,099+2.7% | Added |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.82M | 0.23% | 00.0% | Unchanged |
| UBS Oconnor LLC | 42,412 | $1.84M | 0.05% | +13,788+48.2% | Added |
| Susquehanna Fundamental Investments, LLC | 45,574 | $1.98M | 0.09% | +45,574 | New |
| Twinbeech Capital LP | 46,364 | $2.01M | 0.04% | +16,635+56.0% | Added |
| Private Advisor Group, LLC | 47,976 | $2.08M | 0.01% | −831−1.7% | Reduced |
| Erste Asset Management GmbH | 51,300 | $2.29M | 0.03% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 53,320 | $2.31M | 0.00% | +7,010+15.1% | Added |
| Voya Investment Management LLC | 54,196 | $2.35M | 0.00% | −22,715−29.5% | Reduced |
| Public Employees Retirement System of Ohio | 54,493 | $2.36M | 0.01% | −5,137−8.6% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $2.58M | 0.01% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 59,717 | $2.59M | 0.00% | +140.0% | Added |
| Treasurer of the State of North Carolina | 63,582 | $2.76M | 0.01% | +430+0.7% | Added |
| HealthInvest Partners AB | 63,791 | $2.77M | 1.68% | +39,548+163.1% | Added |
| HRT Financial LP | 66,503 | $2.88M | 0.02% | +66,503 | New |
| Parkwood LLC | 71,259 | $3.09M | 0.33% | −37,295−34.4% | Reduced |
| Nicola Wealth Management Ltd. | 56,000 | $3.29M | 0.32% | 00.0% | Unchanged |
| Citadel Advisors LLC | 78,030 | $3.38M | 0.00% | −174,498−69.1% | Reduced |
| LPL Financial LLC | 79,722 | $3.46M | 0.00% | −7,577−8.7% | Reduced |
| SEI Investments Co | 79,887 | $3.46M | 0.01% | +9,714+13.8% | Added |
| State of New Jersey Common Pension Fund D | 81,847 | $3.55M | 0.01% | 00.0% | Unchanged |
| Commerce Bank | 82,433 | $3.57M | 0.02% | +15,416+23.0% | Added |
| Davenport & Co LLC | 83,928 | $3.64M | 0.02% | −2,400−2.8% | Reduced |
| Trexquant Investment LP | 85,352 | $3.70M | 0.07% | −27,635−24.5% | Reduced |
| Walleye Capital LLC | 89,130 | $3.86M | 0.04% | +89,130 | New |
| Van Eck Associates Corp | 91,101 | $3.95M | 0.01% | +25,270+38.4% | Added |
| State of Wisconsin Investment Board | 91,815 | $3.98M | 0.01% | −11,750−11.3% | Reduced |
| Campbell & CO Investment Adviser LLC | 94,772 | $4.11M | 0.35% | +94,772 | New |
| DekaBank Deutsche Girozentrale | 93,807 | $4.16M | 0.01% | +2,193+2.4% | Added |
| Dimensional Fund Advisors LP | 109,303 | $4.74M | 0.00% | −15,914−12.7% | Reduced |
| Raymond James & Associates | 112,554 | $4.88M | 0.00% | −71,122−38.7% | Reduced |
| Schroder Investment Management Group | 115,658 | $5.01M | 0.01% | +72,658+169.0% | Added |
| Granite Investment Partners, LLC | 116,144 | $5.03M | 0.19% | −3,802−3.2% | Reduced |
| Jane Street Group, LLC | 118,132 | $5.12M | 0.01% | −36,032−23.4% | Reduced |
| Peregrine Capital Management LLC | 118,598 | $5.14M | 0.15% | +10,774+10.0% | Added |
| Superstring Capital Management LP | 120,896 | $5.24M | 3.47% | −68,722−36.2% | Reduced |
| State Board of Administration of Florida Retirement System | 155,145 | $5.54M | 0.01% | +4,090+2.7% | Added |
| Envestnet Asset Management Inc | 129,972 | $5.63M | 0.00% | −3,512−2.6% | Reduced |
| Avidity Partners Management LP | 130,000 | $5.64M | 0.20% | +130,000 | New |
| Susquehanna Portfolio Strategies, LLC | 130,986 | $5.68M | 0.13% | −38,692−22.8% | Reduced |
| California State Teachers Retirement System | 131,818 | $5.71M | 0.01% | −6,714−4.8% | Reduced |
| Amundi | 140,776 | $5.75M | 0.00% | −131,874−48.4% | Reduced |
| New York State Common Retirement Fund | 132,710 | $5.75M | 0.01% | +27,381+26.0% | Added |
| Senator Investment Group LP | 135,000 | $5.85M | 0.27% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 139,061 | $6.03M | 0.01% | +84,928+156.9% | Added |
| Parkman Healthcare Partners LLC | 141,499 | $6.13M | 0.75% | −69,901−33.1% | Reduced |
| Swedbank AB | 142,641 | $6.18M | 0.01% | +1,643+1.2% | Added |
| BLB&B Advisors, LLC | 146,100 | $6.33M | 0.36% | −1,000−0.7% | Reduced |
| Legal & General Group Plc | 149,488 | $6.48M | 0.00% | −5,860−3.8% | Reduced |
| Tang Capital Management LLC | 150,000 | $6.50M | 0.68% | −50,000−25.0% | Reduced |
| Sonora Investment Management Group, LLC | 150,814 | $6.54M | 0.51% | +1,476+1.0% | Added |
| Russell Investments Group, Ltd. | 153,415 | $6.65M | 0.01% | −4,387−2.8% | Reduced |
| Tocqueville Asset Management L.P. | 159,380 | $6.91M | 0.11% | −400−0.3% | Reduced |
| D. E. Shaw & Co., Inc. | 160,482 | $6.96M | 0.01% | +41,324+34.7% | Added |
| Schonfeld Strategic Advisors LLC | 170,860 | $7.41M | 0.06% | −142,414−45.5% | Reduced |
| UBS Group AG | 171,763 | $7.45M | 0.00% | +12,024+7.5% | Added |
| Sector Gamma AS | 175,507 | $7.61M | 2.14% | +30,495+21.0% | Added |
| First Trust Advisors LP | 175,858 | $7.62M | 0.01% | −921,872−84.0% | Reduced |
| Rhumbline Advisers | 179,419 | $7.78M | 0.01% | −19,997−10.0% | Reduced |
| Renaissance Technologies LLC | 179,714 | $7.79M | 0.01% | +67,300+59.9% | Added |
| Credit Suisse AG | 182,509 | $7.91M | 0.01% | −7,213−3.8% | Reduced |
| UBS Asset Management Americas Inc | 186,327 | $8.08M | 0.00% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 191,155 | $8.29M | 0.00% | −66,165−25.7% | Reduced |
| Voloridge Investment Management, LLC | 191,367 | $8.30M | 0.03% | −72,754−27.5% | Reduced |
| Jefferies Financial Group Inc. | 193,080 | $8.37M | 0.17% | −9,220−4.6% | Reduced |
| Sicart Associates LLC | 193,993 | $8.41M | 3.08% | −300−0.2% | Reduced |
| BNP Paribas Arbitrage, SA | 194,359 | $8.43M | 0.01% | −160,596−45.2% | Reduced |
| Altrinsic Global Advisors LLC | 194,864 | $8.45M | 0.38% | −14,288−6.8% | Reduced |
| Goldman Sachs Group Inc | 200,380 | $8.69M | 0.00% | −181,002−47.5% | Reduced |
| California Public Employees Retirement System | 203,945 | $8.84M | 0.01% | −5,491−2.6% | Reduced |
| Rafferty Asset Management, LLC | 208,469 | $9.04M | 0.03% | +24,073+13.1% | Added |
| ExodusPoint Capital Management, LP | 215,893 | $9.36M | 0.12% | +192,409+819.3% | Added |
| Standard Life Aberdeen plc | 219,421 | $9.51M | 0.02% | +83,002+60.8% | Added |
| Nikko Asset Management Americas, Inc. | 220,261 | $9.55M | 0.09% | −32,198−12.8% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 220,261 | $9.55M | 0.01% | −32,198−12.8% | Reduced |
| Citigroup Inc | 222,943 | $9.66M | 0.01% | +122,698+122.4% | Added |
| Privium Fund Management B.V. | 226,993 | $9.84M | 2.63% | +9,500+4.4% | Added |
| J. Goldman & Co LP | 231,424 | $10.0M | 0.45% | +231,424 | New |
| Stifel Financial Corp | 242,459 | $10.5M | 0.01% | −3,570−1.5% | Reduced |
| Bank of Montreal | 222,818 | $10.5M | 0.01% | −571−0.3% | Reduced |
| Manufacturers Life Insurance Company, The | 245,067 | $10.6M | 0.01% | −15,635−6.0% | Reduced |