Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 312
- +12 vs. Q2 2023
- Shares held
- 139.7M
- +6.44M (+4.8%) vs. Q2 2023
- Total value
- $6.35B
- +$878.1M (+16.1%) vs. Q2 2023
- New holders
- 39
- 101 more added
- Sold out
- 27
- 103 more reduced
5 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| UBS Oconnor LLC | 62,059 | $2.81M | 0.05% | −10,000−13.9% | Reduced |
| Treasurer of the State of North Carolina | 62,532 | $2.84M | 0.02% | +310+0.5% | Added |
| Van Eck Associates Corp | 64,687 | $2.93M | 0.01% | +33,326+106.3% | Added |
| SEI Investments Co | 64,711 | $2.94M | 0.01% | +49,401+322.7% | Added |
| Marshall Wace, LLP | 68,127 | $3.09M | 0.01% | −936−1.4% | Reduced |
| State of New Jersey Common Pension Fund D | 77,261 | $3.50M | 0.01% | −3,172−3.9% | Reduced |
| Commerce Bank | 77,647 | $3.52M | 0.03% | −10,635−12.0% | Reduced |
| LPL Financial LLC | 81,816 | $3.71M | 0.00% | −219−0.3% | Reduced |
| Russell Investments Group, Ltd. | 85,995 | $3.90M | 0.01% | −27,335−24.1% | Reduced |
| Davenport & Co LLC | 86,877 | $3.94M | 0.03% | −940−1.1% | Reduced |
| Susquehanna International Group, LLP | 88,739 | $4.03M | 0.01% | −78,777−47.0% | Reduced |
| DekaBank Deutsche Girozentrale | 91,614 | $4.24M | 0.01% | +1,614+1.8% | Added |
| State of Wisconsin Investment Board | 105,765 | $4.80M | 0.01% | −3,545−3.2% | Reduced |
| UBS Group AG | 109,034 | $4.95M | 0.00% | +16,209+17.5% | Added |
| HRT Financial LP | 114,600 | $5.20M | 0.05% | +109,117+1,990.1% | Added |
| New York State Common Retirement Fund | 118,229 | $5.36M | 0.01% | −17,327−12.8% | Reduced |
| Jump Financial, LLC | 119,400 | $5.42M | 0.20% | +13,632+12.9% | Added |
| Peregrine Capital Management LLC | 126,393 | $5.73M | 0.17% | −22,805−15.3% | Reduced |
| Envestnet Asset Management Inc | 126,736 | $5.75M | 0.00% | +90,667+251.4% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 129,812 | $5.89M | 0.03% | −68,696−34.6% | Reduced |
| Invesco Ltd. | 131,167 | $5.95M | 0.00% | +1,449+1.1% | Added |
| Amundi | 125,664 | $6.03M | 0.00% | +4,818+4.0% | Added |
| Verition Fund Management LLC | 136,031 | $6.17M | 0.08% | +136,031 | New |
| Swedbank AB | 136,939 | $6.21M | 0.01% | −799,809−85.4% | Reduced |
| Squarepoint Ops LLC | 139,520 | $6.33M | 0.03% | +71,711+105.8% | Added |
| Point72 Asset Management, L.P. | 141,500 | $6.42M | 0.02% | −62,900−30.8% | Reduced |
| California State Teachers Retirement System | 145,582 | $6.60M | 0.01% | −15,416−9.6% | Reduced |
| BLB&B Advisors, LLC | 147,650 | $6.70M | 0.48% | −2,650−1.8% | Reduced |
| Sonora Investment Management Group, LLC | 148,450 | $6.73M | 0.58% | −1,755−1.2% | Reduced |
| State Board of Administration of Florida Retirement System | 150,988 | $6.85M | 0.02% | +220+0.1% | Added |
| Parkman Healthcare Partners LLC | 159,503 | $7.24M | 1.33% | +6,451+4.2% | Added |
| Jefferies Financial Group Inc. | 160,210 | $7.27M | 0.18% | +67,210+72.3% | Added |
| Tocqueville Asset Management L.P. | 161,730 | $7.34M | 0.14% | −750−0.5% | Reduced |
| Man Group plc | – | $7.44M | 0.02% | – | New |
| Legal & General Group Plc | 165,035 | $7.49M | 0.00% | +31,692+23.8% | Added |
| Sector Gamma AS | 165,616 | $7.51M | 1.92% | +5,215+3.3% | Added |
| UBS Asset Management Americas Inc | 177,114 | $8.03M | 0.00% | +381+0.2% | Added |
| Trexquant Investment LP | 183,349 | $8.32M | 0.21% | +78,724+75.2% | Added |
| Citigroup Inc | 189,620 | $8.60M | 0.01% | +107,873+132.0% | Added |
| Hudson Bay Capital Management LP | 190,000 | $8.62M | 0.08% | −85,000−30.9% | Reduced |
| Dimensional Fund Advisors LP | 192,160 | $8.72M | 0.00% | +9,446+5.2% | Added |
| Raymond James & Associates | 194,629 | $8.83M | 0.01% | +2,745+1.4% | Added |
| Rhumbline Advisers | 197,460 | $8.96M | 0.01% | +127+0.1% | Added |
| Tang Capital Management LLC | 200,000 | $9.07M | 1.28% | 00.0% | Unchanged |
| Sicart Associates LLC | 203,132 | $9.21M | 3.61% | −1,815−0.9% | Reduced |
| Rafferty Asset Management, LLC | 215,971 | $9.80M | 0.06% | +11,583+5.7% | Added |
| Bank of Montreal | 226,821 | $10.1M | 0.01% | +3,690+1.7% | Added |
| Privium Fund Management B.V. | 228,493 | $10.4M | 3.08% | +2,000+0.9% | Added |
| Manufacturers Life Insurance Company, The | 229,677 | $10.4M | 0.01% | −33,882−12.9% | Reduced |
| Credit Suisse AG | 230,343 | $10.4M | 0.01% | −14,639−6.0% | Reduced |
| Kennedy Capital Management, Inc. | 238,635 | $10.8M | 0.26% | +8,374+3.6% | Added |
| Stifel Financial Corp | 246,203 | $11.2M | 0.02% | −22,778−8.5% | Reduced |
| Eversept Partners, LP | 252,446 | $11.5M | 1.27% | +10,874+4.5% | Added |
| Jane Street Group, LLC | 253,491 | $11.5M | 0.02% | +145,167+134.0% | Added |
| Renaissance Technologies LLC | 269,800 | $12.2M | 0.02% | −100,700−27.2% | Reduced |
| Swiss National Bank | 283,100 | $12.8M | 0.01% | +3,000+1.1% | Added |
| Altrinsic Global Advisors LLC | 292,184 | $13.3M | 0.51% | −15,806−5.1% | Reduced |
| Nikko Asset Management Americas, Inc. | 292,473 | $13.3M | 0.16% | −3,659−1.2% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 292,473 | $13.3M | 0.01% | −3,659−1.2% | Reduced |
| Alliancebernstein L.P. | 304,518 | $13.8M | 0.01% | −42,020−12.1% | Reduced |
| CI Private Wealth, LLC | 306,990 | $13.9M | 0.03% | +1,522+0.5% | Added |
| Nuveen Asset Management, LLC | 309,144 | $14.0M | 0.00% | −32,307−9.5% | Reduced |
| Liontrust Investment Partners LLP | 310,026 | $14.1M | 0.22% | −11,548−3.6% | Reduced |
| Woodline Partners LP | 315,094 | $14.3M | 0.17% | −726,838−69.8% | Reduced |
| Baillie Gifford & Co | 316,629 | $14.4M | 0.01% | −13,717−4.2% | Reduced |
| Goldman Sachs Group Inc | 337,827 | $15.3M | 0.00% | +149,455+79.3% | Added |
| D. E. Shaw & Co., Inc. | 362,045 | $16.4M | 0.03% | +165,832+84.5% | Added |
| Jacobs Levy Equity Management, Inc | 373,117 | $16.9M | 0.10% | −176,441−32.1% | Reduced |
| BNP Paribas Arbitrage, SA | 410,674 | $18.6M | 0.04% | +300,158+271.6% | Added |
| Millennium Management LLC | 437,123 | $19.8M | 0.02% | +18,210+4.3% | Added |
| Nomura Holdings Inc | 459,311 | $20.8M | 0.23% | +23,931+5.5% | Added |
| Pinnacle Associates Ltd | 463,035 | $21.0M | 0.39% | −15,169−3.2% | Reduced |
| Two Sigma Investments, LP | 476,057 | $21.6M | 0.06% | +262,685+123.1% | Added |
| AXA S.A. | 481,582 | $21.8M | 0.08% | −43,582−8.3% | Reduced |
| Citadel Advisors LLC | 535,918 | $24.3M | 0.03% | −185,860−25.8% | Reduced |
| Bank of America Corp | 536,044 | $24.3M | 0.00% | +76,725+16.7% | Added |
| Candriam Luxembourg S.C.A. | 549,067 | $24.9M | 0.20% | +25,000+4.8% | Added |
| Two Sigma Advisers, LP | 604,311 | $27.4M | 0.07% | +260,100+75.6% | Added |
| Wells Fargo & Company | 617,930 | $28.0M | 0.01% | +5,039+0.8% | Added |
| Bank of New York Mellon Corp | 627,159 | $28.4M | 0.01% | +69,405+12.4% | Added |
| Barclays PLC | 639,553 | $29.0M | 0.02% | +97,321+17.9% | Added |
| California Public Employees Retirement System | 655,371 | $29.7M | 0.03% | +397,897+154.5% | Added |
| Royal Bank of Canada | 663,444 | $30.1M | 0.01% | +86,306+15.0% | Added |
| Northern Trust Corp | 690,724 | $31.3M | 0.01% | +19,646+2.9% | Added |
| Farallon Capital Management, L.L.C. | 727,000 | $33.0M | 0.19% | +722,000+14,440.0% | Added |
| Capital World Investors | 839,463 | $38.1M | 0.01% | 00.0% | Unchanged |
| TD Asset Management Inc | 898,852 | $40.8M | 0.05% | +113,644+14.5% | Added |
| JPMorgan Chase & Co | 901,057 | $40.9M | 0.00% | −166,666−15.6% | Reduced |
| Morgan Stanley | 1,033,404 | $46.9M | 0.00% | −95,484−8.5% | Reduced |
| Adage Capital Partners GP, L.L.C. | 1,067,000 | $48.4M | 0.11% | +1,067,000 | New |
| First Trust Advisors LP | 1,134,979 | $51.5M | 0.06% | −188,053−14.2% | Reduced |
| Norges Bank | 1,153,926 | $52.3M | 0.01% | +141,308+14.0% | Added |
| Charles Schwab Investment Management Inc | 1,242,307 | $56.4M | 0.02% | +43,087+3.6% | Added |
| Wellington Management Group LLP | 1,760,625 | $79.9M | 0.02% | +845,902+92.5% | Added |
| OrbiMed Advisors LLC | 2,169,500 | $98.4M | 2.28% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 2,194,731 | $99.6M | 0.01% | +37,863+1.8% | Added |
| Camber Capital Management LP | 2,250,000 | $102.1M | 3.66% | −250,000−10.0% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 2,366,367 | $107.3M | 0.82% | −56,264−2.3% | Reduced |
| Deep Track Capital, LP | 2,834,069 | $128.6M | 4.99% | 00.0% | Unchanged |
| Macquarie Group Ltd | 2,935,924 | $133.2M | 0.17% | +1,437,042+95.9% | Added |