Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 305
- −10 vs. Q1 2023
- Shares held
- 136.5M
- +5.40M (+4.1%) vs. Q1 2023
- Total value
- $5.60B
- +$907.9M (+19.3%) vs. Q1 2023
- New holders
- 33
- 97 more added
- Sold out
- 43
- 111 more reduced
Compare with Q1 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| LPL Financial LLC | 82,035 | $3.37M | 0.00% | +13,041+18.9% | Added |
| Cubist Systematic Strategies, LLC | 84,961 | $3.49M | 0.04% | +84,961 | New |
| Davenport & Co LLC | 87,817 | $3.60M | 0.03% | +7,200+8.9% | Added |
| Tekla Capital Management LLC | 87,840 | $3.60M | 0.14% | 00.0% | Unchanged |
| Agf Management Ltd | 87,867 | $3.61M | 0.03% | −6,758−7.1% | Reduced |
| Commerce Bank | 88,282 | $3.62M | 0.03% | +80,736+1,069.9% | Added |
| DekaBank Deutsche Girozentrale | 90,000 | $3.71M | 0.01% | −75,000−45.5% | Reduced |
| UBS Group AG | 92,825 | $3.81M | 0.00% | −8,121−8.0% | Reduced |
| Jefferies Financial Group Inc. | 93,000 | $3.82M | 0.08% | +93,000 | New |
| Public Sector Pension Investment Board | 98,000 | $4.02M | 0.03% | 00.0% | Unchanged |
| Trexquant Investment LP | 104,625 | $4.29M | 0.11% | +72,013+220.8% | Added |
| Jump Financial, LLC | 105,768 | $4.34M | 0.16% | +105,768 | New |
| Jane Street Group, LLC | 108,324 | $4.44M | 0.01% | +4,423+4.3% | Added |
| State of Wisconsin Investment Board | 109,310 | $4.48M | 0.01% | −5,941−5.2% | Reduced |
| Eventide Asset Management, LLC | 110,000 | $4.51M | 0.08% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 110,516 | $4.53M | 0.01% | +11,401+11.5% | Added |
| Russell Investments Group, Ltd. | 113,330 | $4.65M | 0.01% | +9,854+9.5% | Added |
| Amundi | 120,846 | $4.96M | 0.00% | +115,478+2,151.2% | Added |
| Balyasny Asset Management LLC | 125,850 | $5.16M | 0.01% | −77,616−38.1% | Reduced |
| Invesco Ltd. | 129,718 | $5.32M | 0.00% | −186,002−58.9% | Reduced |
| Legal & General Group Plc | 133,343 | $5.47M | 0.00% | −7,375−5.2% | Reduced |
| New York State Common Retirement Fund | 135,556 | $5.56M | 0.01% | +1,556+1.2% | Added |
| Peregrine Capital Management LLC | 149,198 | $6.12M | 0.17% | −490.0% | Reduced |
| Sonora Investment Management Group, LLC | 150,205 | $6.16M | 0.52% | −2,628−1.7% | Reduced |
| BLB&B Advisors, LLC | 150,300 | $6.17M | 0.43% | +1,340+0.9% | Added |
| State Board of Administration of Florida Retirement System | 150,768 | $6.19M | 0.01% | −4,377−2.8% | Reduced |
| Parkman Healthcare Partners LLC | 153,052 | $6.28M | 1.09% | +1,891+1.3% | Added |
| UBS Asset Management Americas Inc | 176,733 | $6.32M | 0.00% | 00.0% | Unchanged |
| Sector Gamma AS | 160,401 | $6.58M | 1.47% | +13,960+9.5% | Added |
| California State Teachers Retirement System | 160,998 | $6.61M | 0.01% | −4,182−2.5% | Reduced |
| Tocqueville Asset Management L.P. | 162,480 | $6.67M | 0.12% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 167,516 | $6.87M | 0.01% | +111,596+199.6% | Added |
| Dimensional Fund Advisors LP | 182,714 | $7.50M | 0.00% | −260,171−58.7% | Reduced |
| Goldman Sachs Group Inc | 188,372 | $7.73M | 0.00% | −233,726−55.4% | Reduced |
| Raymond James & Associates | 191,884 | $7.87M | 0.01% | −9,070−4.5% | Reduced |
| D. E. Shaw & Co., Inc. | 196,213 | $8.05M | 0.01% | +109,562+126.4% | Added |
| Rhumbline Advisers | 197,333 | $8.10M | 0.01% | +20,648+11.7% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 198,508 | $8.14M | 0.04% | −80,250−28.8% | Reduced |
| Tang Capital Management LLC | 200,000 | $8.21M | 1.21% | 00.0% | Unchanged |
| Rafferty Asset Management, LLC | 204,388 | $8.39M | 0.05% | +501+0.2% | Added |
| Point72 Asset Management, L.P. | 204,400 | $8.39M | 0.03% | +108,515+113.2% | Added |
| Sicart Associates LLC | 204,947 | $8.41M | 3.27% | −5,751−2.7% | Reduced |
| Two Sigma Investments, LP | 213,372 | $8.75M | 0.02% | +190,292+824.5% | Added |
| Bank of Montreal | 223,131 | $9.28M | 0.01% | +9,200+4.3% | Added |
| Privium Fund Management B.V. | 226,493 | $9.31M | 2.68% | +43,720+23.9% | Added |
| Kennedy Capital Management, Inc. | 230,261 | $9.45M | 0.22% | +47,836+26.2% | Added |
| Eversept Partners, LP | 241,572 | $9.91M | 1.05% | −61,797−20.4% | Reduced |
| Credit Suisse AG | 244,982 | $10.1M | 0.01% | +2,911+1.2% | Added |
| California Public Employees Retirement System | 257,474 | $10.6M | 0.01% | −24,852−8.8% | Reduced |
| Manufacturers Life Insurance Company, The | 263,559 | $10.8M | 0.01% | +190,947+263.0% | Added |
| Stifel Financial Corp | 268,981 | $11.0M | 0.02% | −850−0.3% | Reduced |
| Hudson Bay Capital Management LP | 275,000 | $11.3M | 0.11% | −30,800−10.1% | Reduced |
| Swiss National Bank | 280,100 | $11.5M | 0.01% | +4,200+1.5% | Added |
| Nikko Asset Management Americas, Inc. | 296,132 | $12.1M | 0.13% | −1,337−0.4% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 296,132 | $12.2M | 0.01% | −1,337−0.4% | Reduced |
| CI Private Wealth, LLC | 305,468 | $12.5M | 0.03% | +182+0.1% | Added |
| Altrinsic Global Advisors LLC | 307,990 | $12.6M | 0.48% | −14,291−4.4% | Reduced |
| Liontrust Investment Partners LLP | 321,574 | $13.2M | 0.19% | −16,027−4.7% | Reduced |
| Baillie Gifford & Co | 330,346 | $13.6M | 0.01% | −2,313−0.7% | Reduced |
| Nuveen Asset Management, LLC | 341,451 | $14.0M | 0.00% | +27,586+8.8% | Added |
| Two Sigma Advisers, LP | 344,211 | $14.1M | 0.04% | −1,600−0.5% | Reduced |
| Alliancebernstein L.P. | 346,538 | $14.2M | 0.01% | +297,938+613.0% | Added |
| Renaissance Technologies LLC | 370,500 | $15.2M | 0.02% | −265,814−41.8% | Reduced |
| Millennium Management LLC | 418,913 | $17.2M | 0.02% | +373,550+823.5% | Added |
| Nomura Holdings Inc | 435,380 | $17.9M | 0.18% | +34,057+8.5% | Added |
| Bank of America Corp | 459,319 | $18.8M | 0.00% | −173,325−27.4% | Reduced |
| Pinnacle Associates Ltd | 478,204 | $19.6M | 0.34% | −12,451−2.5% | Reduced |
| Candriam Luxembourg S.C.A. | 524,067 | $21.5M | 0.16% | +78,870+17.7% | Added |
| AXA S.A. | 525,164 | $21.5M | 0.07% | +4,296+0.8% | Added |
| Barclays PLC | 542,232 | $22.2M | 0.01% | +83,415+18.2% | Added |
| Jacobs Levy Equity Management, Inc | 549,558 | $22.5M | 0.13% | +12,870+2.4% | Added |
| Bank of New York Mellon Corp | 557,754 | $22.9M | 0.00% | −8,341−1.5% | Reduced |
| Royal Bank of Canada | 577,138 | $23.7M | 0.01% | +81,181+16.4% | Added |
| Wells Fargo & Company | 612,891 | $25.1M | 0.01% | −13,259−2.1% | Reduced |
| Northern Trust Corp | 671,078 | $27.5M | 0.01% | +12,612+1.9% | Added |
| Citadel Advisors LLC | 721,778 | $29.6M | 0.03% | +570,255+376.3% | Added |
| TD Asset Management Inc | 785,208 | $32.2M | 0.04% | −32,100−3.9% | Reduced |
| Capital World Investors | 839,463 | $34.4M | 0.01% | +839,463 | New |
| Wellington Management Group LLP | 914,723 | $37.5M | 0.01% | +914,723 | New |
| Swedbank AB | 936,748 | $38.4M | 0.07% | −24,926−2.6% | Reduced |
| Thrivent Financial for Lutherans | 987,450 | $40.5M | 0.09% | +54,910+5.9% | Added |
| Norges Bank | 1,012,618 | $41.5M | 0.01% | −120,073−10.6% | Reduced |
| Woodline Partners LP | 1,041,932 | $42.8M | 0.51% | +1,041,932 | New |
| JPMorgan Chase & Co | 1,067,723 | $43.8M | 0.01% | +10,328+1.0% | Added |
| Morgan Stanley | 1,128,888 | $46.3M | 0.00% | +125,879+12.6% | Added |
| Charles Schwab Investment Management Inc | 1,199,220 | $49.2M | 0.01% | +12,827+1.1% | Added |
| First Trust Advisors LP | 1,323,032 | $54.3M | 0.06% | −315,911−19.3% | Reduced |
| Macquarie Group Ltd | 1,498,882 | $61.5M | 0.07% | +4,979+0.3% | Added |
| Geode Capital Management, LLC | 2,156,868 | $88.5M | 0.01% | +86,918+4.2% | Added |
| OrbiMed Advisors LLC | 2,169,500 | $89.0M | 1.73% | +45,000+2.1% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 2,422,631 | $99.4M | 0.66% | −214,561−8.1% | Reduced |
| Camber Capital Management LP | 2,500,000 | $102.6M | 3.34% | +575,000+29.9% | Added |
| Deep Track Capital, LP | 2,834,069 | $116.3M | 5.43% | 00.0% | Unchanged |
| BVF Inc | 2,846,015 | $116.8M | 3.25% | +285,254+11.1% | Added |
| Pictet Asset Management SA | 3,095,670 | $127.0M | 0.15% | +1,982,628+178.1% | Added |
| Tweedy, Browne Co LLC | 3,540,858 | $145.3M | 7.63% | −1880.0% | Reduced |
| Price T Rowe Associates Inc | 3,835,867 | $157.4M | 0.02% | −99,084−2.5% | Reduced |
| State Street Corp | 3,974,453 | $163.1M | 0.01% | −93,881−2.3% | Reduced |
| Clearbridge Investments, LLC | 5,187,204 | $212.8M | 0.19% | −204,377−3.8% | Reduced |
| BlackRock Inc. | 9,136,174 | $374.9M | 0.01% | +153,928+1.7% | Added |