Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 339
- −4 vs. Q3 2022
- Shares held
- 130.6M
- +4.77M (+3.8%) vs. Q3 2022
- Total value
- $4.93B
- −$630.7M (−11.3%) vs. Q3 2022
- New holders
- 50
- 115 more added
- Sold out
- 54
- 107 more reduced
7 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Seven Eight Capital, LP | 5,990 | $226.2K | 0.06% | +700+13.2% | Added |
| JustInvest LLC | 6,159 | $232.6K | 0.01% | +950+18.2% | Added |
| IFP Advisors, Inc | 4,838 | $233.0K | 0.01% | −951−16.4% | Reduced |
| First Republic Investment Management, Inc. | 6,209 | $234.5K | 0.00% | −461−6.9% | Reduced |
| Perkins Capital Management Inc | 6,400 | $242.0K | 0.26% | 00.0% | Unchanged |
| MQS Management LLC | 6,547 | $247.3K | 0.17% | +6,547 | New |
| Stonegate Investment Group, LLC | 6,807 | $257.1K | 0.01% | 00.0% | Unchanged |
| Oversea-Chinese Banking CORP Ltd | 6,840 | $258.0K | 0.01% | +6,840 | New |
| Baird Financial Group, Inc. | 6,893 | $261.0K | 0.00% | +121+1.8% | Added |
| Northwestern Mutual Wealth Management Co | 6,917 | $261.3K | 0.00% | −330−4.6% | Reduced |
| Sherbrooke Park Advisers LLC | 7,000 | $264.4K | 0.19% | +7,000 | New |
| Stephens Inc | 7,003 | $264.5K | 0.01% | −2,122−23.3% | Reduced |
| Calamos Advisors LLC | 7,026 | $265.4K | 0.00% | −10,093−59.0% | Reduced |
| Tanaka Capital Management Inc | 7,112 | $269.0K | 0.85% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 7,272 | $275.0K | 0.01% | −4,483−38.1% | Reduced |
| AQR Capital Management LLC | 7,569 | $282.0K | 0.00% | −141−1.8% | Reduced |
| Utah Retirement Systems | 7,500 | $283.3K | 0.00% | 00.0% | Unchanged |
| ETF Managers Group, LLC | 7,649 | $288.9K | 0.01% | +7,649 | New |
| Northeast Financial Consultants Inc | 7,740 | $292.3K | 0.02% | 00.0% | Unchanged |
| Commerce Bank | 7,742 | $292.4K | 0.00% | +311+4.2% | Added |
| Virtus ETF Advisers LLC | 7,900 | $298.4K | 0.16% | +871+12.4% | Added |
| Nicollet Investment Management, Inc. | 7,938 | $300.0K | 0.17% | −570−6.7% | Reduced |
| Horizon Kinetics Asset Management LLC | 8,000 | $302.2K | 0.00% | 00.0% | Unchanged |
| MetLife Investment Management | 8,082 | $305.3K | 0.00% | −205−2.5% | Reduced |
| Wrapmanager Inc | 8,499 | $321.0K | 0.10% | −334−3.8% | Reduced |
| National Asset Management, Inc. | 8,736 | $330.0K | 0.01% | +1,404+19.1% | Added |
| The PNC Financial Services Group, Inc. | 9,267 | $350.0K | 0.00% | −562−5.7% | Reduced |
| Captrust Financial Advisors | 9,528 | $359.9K | 0.00% | +9,528 | New |
| Cambridge Investment Research Advisors, Inc. | 9,555 | $361.0K | 0.00% | −1,367−12.5% | Reduced |
| Grantham, Mayo, Van Otterloo & Co. LLC | 9,700 | $366.4K | 0.00% | +9,700 | New |
| Waddell & Associates, LLC | 10,042 | $379.3K | 0.06% | 00.0% | Unchanged |
| Martingale Asset Management L P | 10,361 | $391.3K | 0.01% | +648+6.7% | Added |
| Oppenheimer Asset Management Inc. | 10,369 | $391.6K | 0.01% | −465−4.3% | Reduced |
| Verition Fund Management LLC | 10,512 | $397.0K | 0.01% | +10,512 | New |
| Vontobel Holding Ltd. | 10,929 | $405.7K | 0.00% | −353−3.1% | Reduced |
| Hanseatic Management Services Inc | 10,811 | $408.0K | 1.03% | −182−1.7% | Reduced |
| Advisor Group Holdings, Inc. | 10,829 | $408.3K | 0.00% | −706−6.1% | Reduced |
| Maryland State Retirement & Pension System | 10,950 | $413.6K | 0.01% | +10,950 | New |
| Neuberger Berman Group LLC | 10,985 | $414.9K | 0.00% | −214−1.9% | Reduced |
| HighTower Advisors, LLC | 11,166 | $421.0K | 0.00% | +2,301+26.0% | Added |
| Plancorp, LLC | 11,212 | $423.5K | 0.02% | −43−0.4% | Reduced |
| E Fund Management Co., Ltd. | 11,272 | $426.0K | 0.04% | +1,102+10.8% | Added |
| Jane Street Group, LLC | 11,480 | $433.6K | 0.00% | −9,149−44.4% | Reduced |
| Brown Advisory Inc | 11,531 | $435.5K | 0.00% | +901+8.5% | Added |
| Delphia (USA) Inc. | 11,612 | $438.6K | 0.51% | +2,015+21.0% | Added |
| Arden Trust Co | 11,710 | $442.3K | 0.09% | −206−1.7% | Reduced |
| Illinois Municipal Retirement Fund | 11,866 | $448.0K | 0.01% | +11,866 | New |
| Van Eck Associates Corp | 12,042 | $455.0K | 0.00% | +10,625+749.8% | Added |
| Comerica Bank | 11,522 | $459.0K | 0.00% | −17−0.1% | Reduced |
| Teza Capital Management LLC | 12,624 | $476.8K | 0.09% | +2,376+23.2% | Added |
| Corton Capital Inc. | 12,638 | $477.3K | 0.39% | +3,215+34.1% | Added |
| Caption Management, LLC | 13,000 | $491.0K | 0.08% | +13,000 | New |
| Storebrand Asset Management AS | 13,062 | $493.4K | 0.00% | 00.0% | Unchanged |
| Lincoln National Corp | 13,099 | $494.7K | 0.01% | +269+2.1% | Added |
| Bleakley Financial Group, LLC | 13,184 | $498.0K | 0.02% | +13,184 | New |
| Ameriprise Financial Inc | 13,331 | $501.0K | 0.00% | −25,372−65.6% | Reduced |
| Creative Planning | 13,428 | $507.2K | 0.00% | −464−3.3% | Reduced |
| Westmount Partners, LLC | 13,462 | $508.5K | 0.26% | +13,462 | New |
| North Star Asset Management Inc | 13,680 | $516.7K | 0.03% | 00.0% | Unchanged |
| Franklin Resources Inc | 13,719 | $518.2K | 0.00% | +2,468+21.9% | Added |
| AtonRa Partners | 13,875 | $524.1K | 0.67% | −3,753−21.3% | Reduced |
| ProShare Advisors LLC | 13,903 | $525.1K | 0.00% | −295−2.1% | Reduced |
| Blair William & Co | 14,644 | $553.1K | 0.00% | −200−1.3% | Reduced |
| US Bancorp | 14,820 | $559.8K | 0.00% | −1,378−8.5% | Reduced |
| Campbell & CO Investment Adviser LLC | 15,018 | $567.2K | 0.14% | +15,018 | New |
| Quantedge Capital Pte Ltd | 15,100 | $570.3K | 0.19% | +15,100 | New |
| Group One Trading, L.P. | 15,463 | $584.0K | 0.02% | +15,463 | New |
| Victory Capital Management Inc | 15,787 | $596.3K | 0.00% | −8−0.1% | Reduced |
| Profund Advisors LLC | 15,845 | $598.5K | 0.04% | +368+2.4% | Added |
| American Trust | 15,970 | $603.2K | 0.06% | +15,970 | New |
| Natixis Advisors, L.P. | 16,203 | $612.0K | 0.00% | +385+2.4% | Added |
| Mariner, LLC | 17,542 | $663.0K | 0.00% | +10,401+145.7% | Added |
| Xponance, Inc. | 17,710 | $668.9K | 0.01% | +2,170+14.0% | Added |
| Handelsbanken Fonder AB | 18,511 | $699.0K | 0.00% | 00.0% | Unchanged |
| Koss-Olinger Consulting, LLC | 18,563 | $701.0K | 0.10% | −17,376−48.3% | Reduced |
| Vestmark Advisory Solutions, Inc. | 18,602 | $702.6K | 0.03% | −6,597−26.2% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 18,697 | $706.2K | 0.00% | +1,963+11.7% | Added |
| Echo Street Capital Management LLC | 19,103 | $721.5K | 0.01% | +12,910+208.5% | Added |
| Public Employees Retirement Association of Colorado | 19,604 | $740.0K | 0.00% | 00.0% | Unchanged |
| Skandinaviska Enskilda Banken AB (publ) | 19,736 | $745.0K | 0.01% | −1,142−5.5% | Reduced |
| Engineers Gate Manager LP | 19,977 | $754.5K | 0.05% | +13,484+207.7% | Added |
| Castle Rock Wealth Management, LLC | 19,385 | $763.4K | 0.34% | −500−2.5% | Reduced |
| Commonwealth Equity Services, LLC | 20,704 | $781.0K | 0.00% | −543−2.6% | Reduced |
| Kestra Advisory Services, LLC | 22,413 | $846.5K | 0.01% | −512−2.2% | Reduced |
| Cantor Fitzgerald, L. P. | 22,880 | $864.0K | 0.02% | +22,880 | New |
| Dynamic Technology Lab Private Ltd | 25,580 | $966.0K | 0.10% | +25,580 | New |
| STRS Ohio | 25,791 | $974.0K | 0.00% | +8,483+49.0% | Added |
| Walleye Capital LLC | 26,054 | $984.1K | 0.02% | −59,909−69.7% | Reduced |
| Great West Life Assurance Co | 26,140 | $993.0K | 0.00% | +9,005+52.6% | Added |
| Federated Hermes, Inc. | 26,579 | $1.00M | 0.00% | +452+1.7% | Added |
| Raymond James Financial Services Advisors, Inc. | 26,725 | $1.01M | 0.00% | −5,839−17.9% | Reduced |
| Pinebridge Investments, L.P. | 26,959 | $1.02M | 0.01% | +26,959 | New |
| Edgestream Partners, L.P. | 27,393 | $1.03M | 0.12% | +27,393 | New |
| Toronto Dominion Bank | 30,706 | $1.16M | 0.00% | −600−1.9% | Reduced |
| Voloridge Investment Management, LLC | 30,709 | $1.16M | 0.01% | +30,709 | New |
| Virginia Retirement Systems Et Al | 30,800 | $1.16M | 0.01% | +4,200+15.8% | Added |
| American Century Companies Inc | 30,872 | $1.17M | 0.00% | +20,793+206.3% | Added |
| Bank of Nova Scotia | 31,000 | $1.17M | 0.00% | +31,000 | New |
| Grandfield & Dodd, LLC | 31,474 | $1.19M | 0.09% | +2,403+8.3% | Added |
| Amalgamated Bank | 32,095 | $1.21M | 0.01% | +503+1.6% | Added |