Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 350
- −1 vs. Q2 2022
- Shares held
- 126.4M
- +1.80M (+1.4%) vs. Q2 2022
- Total value
- $5.59B
- +$976.9M (+21.2%) vs. Q2 2022
- New holders
- 50
- 97 more added
- Sold out
- 51
- 130 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Kestra Advisory Services, LLC | 22,925 | $1.01M | 0.01% | +94+0.4% | Added |
| Capital Fund Management S.A. | 23,023 | $1.02M | 0.03% | −16,087−41.1% | Reduced |
| Janus Henderson Group PLC | 23,140 | $1.02M | 0.00% | −67−0.3% | Reduced |
| Gotham Asset Management, LLC | 23,240 | $1.03M | 0.03% | −38,244−62.2% | Reduced |
| Twin Tree Management, LP | 23,517 | $1.04M | 0.03% | +23,517 | New |
| Vestmark Advisory Solutions, Inc. | 25,199 | $1.11M | 0.06% | +1,604+6.8% | Added |
| Aquatic Capital Management LLC | 25,500 | $1.13M | 0.11% | +25,500 | New |
| Federated Hermes, Inc. | 26,127 | $1.16M | 0.00% | −1,110−4.1% | Reduced |
| Virginia Retirement Systems Et Al | 26,600 | $1.18M | 0.01% | +26,600 | New |
| EAM Investors, LLC | 28,396 | $1.26M | 0.27% | +28,396 | New |
| Allianz Asset Management GmbH | 28,880 | $1.28M | 0.00% | +6,383+28.4% | Added |
| Grandfield & Dodd, LLC | 29,071 | $1.29M | 0.11% | +795+2.8% | Added |
| Toronto Dominion Bank | 31,306 | $1.38M | 0.00% | +31,306 | New |
| Amalgamated Bank | 31,592 | $1.40M | 0.01% | −1,731−5.2% | Reduced |
| Ensign Peak Advisors, Inc | 32,315 | $1.43M | 0.00% | +7,445+29.9% | Added |
| Janney Montgomery Scott LLC | 32,415 | $1.43M | 0.01% | +1,757+5.7% | Added |
| Raymond James Financial Services Advisors, Inc. | 32,564 | $1.44M | 0.00% | −21,666−40.0% | Reduced |
| Arizona State Retirement System | 34,680 | $1.53M | 0.02% | +239+0.7% | Added |
| Koss-Olinger Consulting, LLC | 35,939 | $1.59M | 0.27% | −2,983−7.7% | Reduced |
| Ameriprise Financial Inc | 38,703 | $1.71M | 0.00% | +27,319+240.0% | Added |
| Highland Capital Management, LLC | 38,873 | $1.72M | 0.13% | −286−0.7% | Reduced |
| Envestnet Asset Management Inc | 39,264 | $1.74M | 0.00% | −1,101−2.7% | Reduced |
| Brookstone Capital Management | 38,035 | $1.75M | 0.04% | +12,694+50.1% | Added |
| Capital Counsel LLC | 40,230 | $1.78M | 0.12% | −780−1.9% | Reduced |
| Susquehanna International Group, LLP | 40,870 | $1.81M | 0.00% | +3,317+8.8% | Added |
| Teacher Retirement System of Texas | 41,844 | $1.85M | 0.01% | +21,579+106.5% | Added |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.86M | 0.32% | 00.0% | Unchanged |
| Rhenman & Partners Asset Management AB | 50,000 | $2.21M | 0.23% | 00.0% | Unchanged |
| Gateway Investment Advisers LLC | 50,199 | $2.22M | 0.03% | −48,930−49.4% | Reduced |
| Erste Asset Management GmbH | 51,300 | $2.27M | 0.05% | 00.0% | Unchanged |
| National Bank of Canada | 51,720 | $2.29M | 0.01% | +51,720 | New |
| Graham Capital Management, L.P. | 53,717 | $2.38M | 0.10% | −7,296−12.0% | Reduced |
| UBS Oconnor LLC | 54,497 | $2.41M | 0.03% | −7,000−11.4% | Reduced |
| Guggenheim Capital LLC | 54,969 | $2.43M | 0.02% | −8,777−13.8% | Reduced |
| Trexquant Investment LP | 55,564 | $2.46M | 0.09% | +27,141+95.5% | Added |
| Intech Investment Management LLC | 57,140 | $2.53M | 0.02% | +57,140 | New |
| Alliancebernstein L.P. | 58,102 | $2.57M | 0.00% | −2,758−4.5% | Reduced |
| Principal Financial Group Inc | 60,269 | $2.67M | 0.00% | −51,899−46.3% | Reduced |
| Treasurer of the State of North Carolina | 60,522 | $2.68M | 0.02% | +780+1.3% | Added |
| Algert Global LLC | 60,937 | $2.69M | 0.16% | +36,037+144.7% | Added |
| UBS Group AG | 61,310 | $2.71M | 0.00% | −108,857−64.0% | Reduced |
| Deutsche Bank AG | 65,426 | $2.89M | 0.00% | +32,961+101.5% | Added |
| Voya Investment Management LLC | 70,275 | $3.11M | 0.00% | +13,720+24.3% | Added |
| Cubist Systematic Strategies, LLC | 70,408 | $3.11M | 0.02% | −78,980−52.9% | Reduced |
| Eaton Vance Management | 70,682 | $3.13M | 0.00% | +1,084+1.6% | Added |
| Liontrust Investment Partners LLP | 72,269 | $3.20M | 0.05% | −122,223−62.8% | Reduced |
| LPL Financial LLC | 74,740 | $3.31M | 0.00% | −7,347−9.0% | Reduced |
| PFS Investments Inc. | 75,202 | $3.33M | 0.07% | +1,077+1.5% | Added |
| Public Employees Retirement System of Ohio | 76,123 | $3.37M | 0.02% | +780+1.0% | Added |
| Alps Advisors Inc | 77,480 | $3.43M | 0.03% | −6,635−7.9% | Reduced |
| State of New Jersey Common Pension Fund D | 80,433 | $3.56M | 0.01% | 00.0% | Unchanged |
| Davenport & Co LLC | 84,863 | $3.75M | 0.03% | +1,545+1.9% | Added |
| Walleye Capital LLC | 85,963 | $3.80M | 0.09% | +79,594+1,249.7% | Added |
| Jump Financial, LLC | 86,602 | $3.83M | 0.15% | −28,255−24.6% | Reduced |
| Tekla Capital Management LLC | 87,840 | $3.88M | 0.16% | −87,840−50.0% | Reduced |
| Bard Financial Services, Inc. | 87,895 | $3.89M | 0.36% | −5,550−5.9% | Reduced |
| Manufacturers Life Insurance Company, The | 89,096 | $3.94M | 0.00% | −4,118−4.4% | Reduced |
| Squarepoint Ops LLC | 92,054 | $4.07M | 0.04% | −37,886−29.2% | Reduced |
| Russell Investments Group, Ltd. | 92,320 | $4.08M | 0.01% | −6,914−7.0% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 92,700 | $4.10M | 0.02% | +92,700 | New |
| Jefferies Group LLC | 105,566 | $4.67M | 0.14% | +105,566 | New |
| Private Advisor Group, LLC | 109,872 | $4.86M | 0.06% | −27,910−20.3% | Reduced |
| Eventide Asset Management, LLC | 110,000 | $4.87M | 0.10% | 00.0% | Unchanged |
| Peregrine Capital Management LLC | 123,396 | $5.46M | 0.18% | −6,828−5.2% | Reduced |
| DekaBank Deutsche Girozentrale | 124,776 | $5.50M | 0.02% | 00.0% | Unchanged |
| Legal & General Group Plc | 128,453 | $5.68M | 0.00% | −35,501−21.7% | Reduced |
| State of Wisconsin Investment Board | 129,854 | $5.74M | 0.02% | −7,379−5.4% | Reduced |
| Sonora Investment Management Group, LLC | 157,023 | $5.81M | 0.75% | +700+0.4% | Added |
| BNP Paribas Arbitrage, SA | 132,740 | $5.87M | 0.01% | +12,770+10.6% | Added |
| Natixis | 134,081 | $5.94M | 0.03% | +134,081 | New |
| Fred Alger Management, LLC | 142,522 | $6.30M | 0.03% | −4,134−2.8% | Reduced |
| New York State Common Retirement Fund | 142,900 | $6.32M | 0.01% | −3,925−2.7% | Reduced |
| Kennedy Capital Management, Inc. | 144,795 | $6.40M | 0.19% | +25,113+21.0% | Added |
| Privium Fund Management B.V. | 148,807 | $6.59M | 2.49% | −31,300−17.4% | Reduced |
| BLB&B Advisors, LLC | 149,070 | $6.59M | 0.55% | −180−0.1% | Reduced |
| Rafferty Asset Management, LLC | 151,974 | $6.72M | 0.07% | +32,691+27.4% | Added |
| Susquehanna Fundamental Investments, LLC | 153,636 | $6.79M | 0.12% | +153,636 | New |
| Credit Suisse AG | 154,698 | $6.84M | 0.01% | +4,977+3.3% | Added |
| Rhumbline Advisers | 155,714 | $6.89M | 0.01% | +1,212+0.8% | Added |
| Altrinsic Global Advisors LLC | 161,246 | $7.13M | 0.33% | −25,208−13.5% | Reduced |
| Tocqueville Asset Management L.P. | 162,394 | $7.18M | 0.15% | −211−0.1% | Reduced |
| State Board of Administration of Florida Retirement System | 163,255 | $7.22M | 0.02% | −870−0.5% | Reduced |
| Sector Gamma AS | 164,223 | $7.26M | 1.87% | −1,216−0.7% | Reduced |
| California State Teachers Retirement System | 165,925 | $7.34M | 0.01% | −3,489−2.1% | Reduced |
| Citigroup Inc | 176,992 | $7.83M | 0.01% | +27,861+18.7% | Added |
| Man Group plc | 177,597 | $7.86M | 0.04% | – | – |
| AXA S.A. | 182,356 | $8.07M | 0.03% | +23,821+15.0% | Added |
| Hudson Bay Capital Management LP | 199,800 | $8.84M | 0.09% | +14,800+8.0% | Added |
| Tang Capital Management LLC | 200,000 | $8.85M | 1.08% | 00.0% | Unchanged |
| Eversept Partners, LP | 201,833 | $8.93M | 1.06% | +115,522+133.8% | Added |
| Schonfeld Strategic Advisors LLC | 207,672 | $9.19M | 0.08% | +77,649+59.7% | Added |
| D. E. Shaw & Co., Inc. | 209,445 | $9.26M | 0.02% | +82,824+65.4% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 229,061 | $10.1M | 0.07% | +97,078+73.6% | Added |
| Raymond James & Associates | 238,168 | $10.5M | 0.01% | −8,281−3.4% | Reduced |
| Parkman Healthcare Partners LLC | 241,945 | $10.7M | 3.04% | +67,645+38.8% | Added |
| Sicart Associates LLC | 253,976 | $11.2M | 3.98% | −34,775−12.0% | Reduced |
| Pictet Asset Management SA | 276,977 | $12.3M | 0.02% | +38,638+16.2% | Added |
| UBS Asset Management Americas Inc | 279,624 | $12.4M | 0.01% | +73,835+35.9% | Added |
| Two Sigma Investments, LP | 292,994 | $13.0M | 0.04% | −267,037−47.7% | Reduced |
| Invesco Ltd. | 295,199 | $13.1M | 0.00% | −30,786−9.4% | Reduced |