Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 351
- +22 vs. Q1 2022
- Shares held
- 124.6M
- +27.5K (0.0%) vs. Q1 2022
- Total value
- $4.61B
- −$315.6K (0.0%) vs. Q1 2022
- New holders
- 53
- 89 more added
- Sold out
- 31
- 130 more reduced
4 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Raymond James & Associates | 246,449 | $9.12M | 0.01% | −10,277−4.0% | Reduced |
| Bank of Montreal | 231,992 | $9.22M | 0.01% | −36,505−13.6% | Reduced |
| California Public Employees Retirement System | 282,382 | $10.5M | 0.01% | −12,433−4.2% | Reduced |
| Sicart Associates LLC | 288,751 | $10.7M | 3.33% | −16,031−5.3% | Reduced |
| Swiss National Bank | 299,300 | $11.1M | 0.01% | −1,200−0.4% | Reduced |
| Dowling & Yahnke LLC | 302,571 | $11.2M | 0.53% | 00.0% | Unchanged |
| Stifel Financial Corp | 306,320 | $11.3M | 0.02% | −34,246−10.1% | Reduced |
| Baillie Gifford & Co | 311,015 | $11.5M | 0.01% | −37,848−10.8% | Reduced |
| Millennium Management LLC | 320,615 | $11.9M | 0.02% | +129,424+67.7% | Added |
| Invesco Ltd. | 325,985 | $12.1M | 0.00% | +185,993+132.9% | Added |
| Assenagon Asset Management S.A. | 340,716 | $12.6M | 0.05% | −17,180−4.8% | Reduced |
| Nuveen Asset Management, LLC | 348,686 | $12.9M | 0.01% | +32,867+10.4% | Added |
| Barclays PLC | 354,579 | $13.1M | 0.01% | +38,229+12.1% | Added |
| Nomura Holdings Inc | 375,977 | $14.3M | 0.13% | −18,177−4.6% | Reduced |
| Nikko Asset Management Americas, Inc. | 468,116 | $15.4M | 0.19% | −131,500−21.9% | Reduced |
| Royal Bank of Canada | 428,423 | $15.9M | 0.00% | −16,079−3.6% | Reduced |
| OrbiMed Advisors LLC | 453,400 | $16.8M | 0.33% | +453,400 | New |
| Sumitomo Mitsui Trust Holdings, Inc. | 468,116 | $17.3M | 0.01% | −131,500−21.9% | Reduced |
| Citadel Advisors LLC | 480,143 | $17.8M | 0.02% | −764,381−61.4% | Reduced |
| Pinnacle Associates Ltd | 515,859 | $19.1M | 0.42% | −6,109−1.2% | Reduced |
| Two Sigma Investments, LP | 560,031 | $20.7M | 0.07% | −220,225−28.2% | Reduced |
| Candriam Luxembourg S.C.A. | 570,692 | $21.1M | 0.17% | +71,145+14.2% | Added |
| Dimensional Fund Advisors LP | 585,048 | $21.7M | 0.01% | +231,567+65.5% | Added |
| Bank of America Corp | 608,552 | $22.5M | 0.00% | −153,606−20.2% | Reduced |
| Renaissance Technologies LLC | 614,814 | $22.8M | 0.03% | +479,900+355.7% | Added |
| Jacobs Levy Equity Management, Inc | 616,766 | $22.8M | 0.18% | −1,001,501−61.9% | Reduced |
| Northern Trust Corp | 625,472 | $23.2M | 0.00% | −23,062−3.6% | Reduced |
| Bank of New York Mellon Corp | 665,316 | $24.6M | 0.01% | +116,069+21.1% | Added |
| Two Sigma Advisers, LP | 705,811 | $26.1M | 0.07% | +94,200+15.4% | Added |
| Wells Fargo & Company | 723,995 | $26.8M | 0.01% | −118,289−14.0% | Reduced |
| Morgan Stanley | 737,977 | $27.3M | 0.00% | +218,500+42.1% | Added |
| TD Asset Management Inc | 803,664 | $29.8M | 0.03% | −16,500−2.0% | Reduced |
| Swedbank AB | 1,022,281 | $37.8M | 0.09% | −95,058−8.5% | Reduced |
| JPMorgan Chase & Co | 1,039,570 | $38.5M | 0.01% | −141,987−12.0% | Reduced |
| Goldman Sachs Group Inc | 1,041,824 | $38.6M | 0.01% | +87,498+9.2% | Added |
| Norges Bank | 1,118,341 | $41.4M | 0.01% | +332,780+42.4% | Added |
| Charles Schwab Investment Management Inc | 1,154,025 | $42.7M | 0.01% | +16,198+1.4% | Added |
| BVF Inc | 1,276,574 | $47.3M | 2.28% | +1,276,574 | New |
| Thrivent Financial for Lutherans | 1,276,783 | $47.3M | 0.13% | −284,730−18.2% | Reduced |
| First Trust Advisors LP | 1,596,055 | $59.1M | 0.07% | −20,235−1.3% | Reduced |
| Geode Capital Management, LLC | 1,865,133 | $69.0M | 0.01% | −32,359−1.7% | Reduced |
| Camber Capital Management LP | 2,700,000 | $100.0M | 4.34% | −300,000−10.0% | Reduced |
| Tweedy, Browne Co LLC | 2,726,778 | $100.9M | 4.13% | −198,324−6.8% | Reduced |
| State Street Corp | 4,202,874 | $155.6M | 0.01% | +172,228+4.3% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 4,701,297 | $171.7M | 1.02% | −1,470,011−23.8% | Reduced |
| Clearbridge Investments, LLC | 6,005,818 | $222.3M | 0.21% | −470,215−7.3% | Reduced |
| BlackRock Inc. | 8,831,390 | $326.9M | 0.01% | +387,547+4.6% | Added |
| Bellevue Group AG | 9,776,528 | $361.9M | 5.12% | −141,545−1.4% | Reduced |
| Vanguard Group Inc | 12,200,276 | $451.7M | 0.01% | +101,242+0.8% | Added |
| Price T Rowe Associates Inc | 15,056,046 | $557.4M | 0.07% | +705,586+4.9% | Added |
| FMR LLC | 21,269,560 | $787.4M | 0.08% | −51,326−0.2% | Reduced |
| Proequities, Inc. | 0 | $0 | 0.00% | −214−100.0% | Sold out |
| Morningstar Investment Services LLC | 0 | $0 | 0.00% | −222,681−100.0% | Sold out |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −189,556−100.0% | Sold out |
| Sio Capital Management, LLC | 0 | $0 | 0.00% | −175,568−100.0% | Sold out |
| Weiss Asset Management LP | 0 | $0 | 0.00% | −18,145−100.0% | Sold out |
| Bradley Foster & Sargent Inc | 0 | $0 | 0.00% | −17,050−100.0% | Sold out |
| SG3 Management, LLC | 0 | $0 | 0.00% | −14,780−100.0% | Sold out |
| Cowen and Company, LLC | 0 | $0 | 0.00% | −13,257−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −10,689−100.0% | Sold out |
| Pearl River Capital, LLC | 0 | $0 | 0.00% | −10,153−100.0% | Sold out |
| Brown Advisory Securities, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Regions Financial Corp | 0 | $0 | 0.00% | −9,323−100.0% | Sold out |
| Boston Partners | 0 | $0 | 0.00% | −8,037−100.0% | Sold out |
| IHT Wealth Management, LLC | 0 | $0 | 0.00% | −7,878−100.0% | Sold out |
| Echo Street Capital Management LLC | 0 | $0 | 0.00% | −7,223−100.0% | Sold out |
| Beacon Pointe Advisors, LLC | 0 | $0 | 0.00% | −7,055−100.0% | Sold out |
| Foundations Investment Advisors, LLC | 0 | $0 | 0.00% | −6,355−100.0% | Sold out |
| FORA Capital, LLC | 0 | $0 | 0.00% | −6,095−100.0% | Sold out |
| CIBC Asset Management Inc | 0 | $0 | 0.00% | −5,583−100.0% | Sold out |
| FDx Advisors, Inc. | 0 | $0 | 0.00% | −5,575−100.0% | Sold out |
| Mitchell & Pahl Private Wealth, LLC | 0 | $0 | 0.00% | −5,489−100.0% | Sold out |
| Beaird Harris Wealth Management, LLC | 0 | $0 | 0.00% | −5,000−100.0% | Sold out |
| Point72 Hong Kong Ltd | 0 | $0 | 0.00% | −2,427−100.0% | Sold out |
| Koshinski Asset Management, Inc. | 0 | $0 | 0.00% | −2,013−100.0% | Sold out |
| Twin Lakes Capital Management, LLC | 0 | $0 | 0.00% | −1,500−100.0% | Sold out |
| Bessemer Group Inc | 0 | $0 | 0.00% | −900−100.0% | Sold out |
| McCarthy Asset Management, Inc. | 0 | $0 | 0.00% | −110−100.0% | Sold out |
| Dark Forest Capital Management LP | 0 | $0 | 0.00% | −49−100.0% | Sold out |
| AdvisorNet Financial, Inc | 0 | $0 | 0.00% | −29−100.0% | Sold out |
| FourThought Financial, LLC | 0 | $0 | 0.00% | −27−100.0% | Sold out |
| TCWP LLC | 0 | $0 | 0.00% | −38−100.0% | Sold out |
| Parametric Portfolio Associates LLC | – | – | – | – | Not filed |
| Majedie Asset Management Ltd | – | – | – | – | Not filed |
| Amalgamated Financial Corp. | – | – | – | – | Not filed |
| IndexIQ Advisors LLC | – | – | – | – | Not filed |