Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2021
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 338
- −24 vs. Q1 2021
- Shares held
- 124.4M
- +2.62M (+2.2%) vs. Q1 2021
- Total value
- $4.96B
- −$516.2M (−9.4%) vs. Q1 2021
- New holders
- 51
- 116 more added
- Sold out
- 75
- 103 more reduced
3 institutions that held it in Q1 2021 haven't filed for Q2 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2021
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Handelsbanken Fonder AB | 24,411 | $974.0K | 0.01% | +1,400+6.1% | Added |
| Truist Financial Corp | 25,101 | $1.00M | 0.00% | +3,437+15.9% | Added |
| Stephens Inc | 25,638 | $1.02M | 0.02% | +482+1.9% | Added |
| Commonwealth Equity Services, LLC | 25,730 | $1.03M | 0.00% | +7,594+41.9% | Added |
| Utah Retirement Systems | 26,709 | $1.06M | 0.01% | +1,600+6.4% | Added |
| Amalgamated Bank | 26,933 | $1.07M | 0.01% | +7,267+37.0% | Added |
| Eaton Vance Management | 27,074 | $1.08M | 0.00% | +604+2.3% | Added |
| Cowen and Company, LLC | 27,708 | $1.10M | 0.06% | +20,627+291.3% | Added |
| Twin Tree Management, LP | 29,382 | $1.17M | 0.04% | +29,382 | New |
| ProShare Advisors LLC | 30,423 | $1.21M | 0.00% | +8,288+37.4% | Added |
| Edgestream Partners, L.P. | 31,262 | $1.25M | 0.07% | +31,262 | New |
| Group One Trading, L.P. | 31,530 | $1.26M | 0.02% | +2,619+9.1% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 32,293 | $1.29M | 0.01% | −22,200−40.7% | Reduced |
| Employees Retirement System of Texas | 32,409 | $1.29M | 0.02% | 00.0% | Unchanged |
| Macquarie Group Ltd | 32,428 | $1.29M | 0.00% | +1,971+6.5% | Added |
| Great West Life Assurance Co | 33,166 | $1.32M | 0.00% | −24,310−42.3% | Reduced |
| Seeyond | 33,852 | $1.35M | 0.13% | +151+0.4% | Added |
| First Foundation Advisors | 34,449 | $1.37M | 0.05% | +4,386+14.6% | Added |
| Arizona State Retirement System | 34,461 | $1.38M | 0.01% | −3,838−10.0% | Reduced |
| Storebrand Asset Management AS | 35,422 | $1.41M | 0.01% | −1,931−5.2% | Reduced |
| Gateway Investment Advisers LLC | 37,600 | $1.50M | 0.02% | 00.0% | Unchanged |
| Janney Montgomery Scott LLC | 38,646 | $1.54M | 0.01% | +1,834+5.0% | Added |
| Capital Counsel LLC | 40,580 | $1.62M | 0.08% | −1,500−3.6% | Reduced |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.68M | 0.22% | 00.0% | Unchanged |
| Voya Investment Management LLC | 43,419 | $1.73M | 0.00% | +12,708+41.4% | Added |
| Raymond James Financial Services Advisors, Inc. | 44,831 | $1.79M | 0.00% | +9,302+26.2% | Added |
| Jane Street Group, LLC | 46,417 | $1.85M | 0.00% | +13,554+41.2% | Added |
| Squarepoint Ops LLC | 47,745 | $1.91M | 0.01% | +28,158+143.8% | Added |
| Principal Financial Group Inc | 47,970 | $1.91M | 0.00% | +3,559+8.0% | Added |
| Treasurer of the State of North Carolina | 48,807 | $1.95M | 0.01% | +890+1.9% | Added |
| Erste Asset Management GmbH | 51,300 | $2.03M | 0.04% | +16,800+48.7% | Added |
| Guggenheim Capital LLC | 56,136 | $2.24M | 0.01% | −15,256−21.4% | Reduced |
| LPL Financial LLC | 59,316 | $2.37M | 0.00% | +4,033+7.3% | Added |
| Jump Financial, LLC | 62,400 | $2.49M | 0.24% | +62,400 | New |
| Jefferies Group LLC | 66,704 | $2.66M | 0.05% | +46,577+231.4% | Added |
| Rafferty Asset Management, LLC | 68,772 | $2.74M | 0.02% | +5,888+9.4% | Added |
| Alliancebernstein L.P. | 69,803 | $2.78M | 0.00% | −7,497−9.7% | Reduced |
| SG3 Management, LLC | 72,300 | $2.88M | 1.23% | +52,300+261.5% | Added |
| PFS Investments Inc. | 75,715 | $2.94M | 0.07% | +5,211+7.4% | Added |
| D. E. Shaw & Co., Inc. | 74,666 | $2.98M | 0.00% | +66,560+821.1% | Added |
| Rhenman & Partners Asset Management AB | 75,000 | $2.99M | 0.20% | 00.0% | Unchanged |
| Sabby Management, LLC | 78,000 | $3.11M | 0.67% | +23,312+42.6% | Added |
| Public Employees Retirement System of Ohio | 80,054 | $3.19M | 0.01% | +10,669+15.4% | Added |
| State of New Jersey Common Pension Fund D | 86,745 | $3.46M | 0.01% | +1,822+2.1% | Added |
| Susquehanna Fundamental Investments, LLC | 88,273 | $3.52M | 0.06% | +33,469+61.1% | Added |
| Arrowstreet Capital, Limited Partnership | 92,900 | $3.71M | 0.00% | +92,900 | New |
| Envestnet Asset Management Inc | 95,720 | $3.82M | 0.00% | +13,400+16.3% | Added |
| Caption Management, LLC | 96,007 | $3.83M | 0.34% | +96,007 | New |
| Tudor Investment Corp Et Al | 99,886 | $3.98M | 0.08% | +99,886 | New |
| DekaBank Deutsche Girozentrale | 107,576 | $4.26M | 0.01% | −9,819−8.4% | Reduced |
| Wolverine Trading, LLC | 110,948 | $4.39M | 0.12% | +1,337+1.2% | Added |
| Davenport & Co LLC | 116,963 | $4.66M | 0.04% | −7,775−6.2% | Reduced |
| Thrivent Financial for Lutherans | 123,367 | $4.92M | 0.01% | +2,054+1.7% | Added |
| Legal & General Group Plc | 125,883 | $5.02M | 0.00% | −294,494−70.1% | Reduced |
| Pictet Asset Management Ltd | 134,324 | $5.36M | 0.01% | +85,324+174.1% | Added |
| Parkman Healthcare Partners LLC | 136,380 | $5.44M | 1.19% | +30,583+28.9% | Added |
| Rhumbline Advisers | 139,585 | $5.57M | 0.01% | −4,821−3.3% | Reduced |
| PDT Partners, LLC | 141,925 | $5.66M | 0.37% | +141,925 | New |
| Van Eck Associates Corp | 147,383 | $5.88M | 0.01% | −22,609−13.3% | Reduced |
| UBS Group AG | 155,129 | $6.19M | 0.00% | +126,067+433.8% | Added |
| BLB&B Advisors, LLC | 157,490 | $6.28M | 0.45% | +870+0.6% | Added |
| Credit Suisse AG | 159,185 | $6.35M | 0.00% | +26,191+19.7% | Added |
| Peregrine Capital Management LLC | 162,528 | $6.48M | 0.12% | −9,820−5.7% | Reduced |
| State Board of Administration of Florida Retirement System | 164,108 | $6.55M | 0.01% | −4,865−2.9% | Reduced |
| Sonora Investment Management, LLC | 168,665 | $6.73M | 0.88% | +4,742+2.9% | Added |
| Tocqueville Asset Management L.P. | 172,200 | $6.87M | 0.10% | −73,292−29.9% | Reduced |
| Ergoteles LLC | 176,253 | $7.03M | 0.16% | +176,253 | New |
| UBS Asset Management Americas Inc | 176,341 | $7.03M | 0.00% | −228,183−56.4% | Reduced |
| Marshall Wace, LLP | 176,820 | $7.05M | 0.04% | +176,820 | New |
| Cubist Systematic Strategies, LLC | 178,142 | $7.11M | 0.08% | +178,142 | New |
| International Biotechnology Trust PLC | 181,781 | $7.25M | 1.93% | −152,000−45.5% | Reduced |
| Majedie Asset Management Ltd | 184,462 | $7.36M | 0.48% | +62,763+51.6% | Added |
| Hudson Bay Capital Management LP | 185,000 | $7.38M | 0.09% | +54,600+41.9% | Added |
| Morningstar Investment Services LLC | 210,107 | $8.31M | 0.10% | +7,400+3.7% | Added |
| Parametric Portfolio Associates LLC | 220,212 | $8.78M | 0.00% | −1,589−0.7% | Reduced |
| Russell Investments Group, Ltd. | 221,554 | $8.84M | 0.01% | +190,623+616.3% | Added |
| American Century Companies Inc | 226,180 | $9.02M | 0.01% | −716,498−76.0% | Reduced |
| Deutsche Bank AG | 234,386 | $9.35M | 0.00% | +73,819+46.0% | Added |
| New York State Common Retirement Fund | 241,159 | $9.62M | 0.01% | +42,928+21.7% | Added |
| Citigroup Inc | 242,123 | $9.66M | 0.01% | +7,103+3.0% | Added |
| California State Teachers Retirement System | 243,722 | $9.72M | 0.01% | −1,361−0.6% | Reduced |
| Worldquant Millennium Advisors LLC | 251,075 | $10.0M | 0.22% | +251,075 | New |
| Balyasny Asset Management LLC | 263,286 | $10.5M | 0.06% | +263,286 | New |
| Sector Gamma AS | 263,488 | $10.5M | 1.86% | −190,662−42.0% | Reduced |
| Baillie Gifford & Co | 271,396 | $10.8M | 0.01% | +33,437+14.1% | Added |
| Swiss National Bank | 279,900 | $11.2M | 0.01% | −230,459−45.2% | Reduced |
| Bank Julius Baer & Co. Ltd, Zurich | 288,844 | $11.5M | 0.07% | +917+0.3% | Added |
| Raymond James & Associates | 293,938 | $11.7M | 0.01% | −8,137−2.7% | Reduced |
| Dowling & Yahnke LLC | 303,150 | $12.1M | 0.69% | −700.0% | Reduced |
| Two Sigma Investments, LP | 306,488 | $12.2M | 0.03% | +120,768+65.0% | Added |
| California Public Employees Retirement System | 320,680 | $12.8M | 0.01% | +4,103+1.3% | Added |
| Tekla Capital Management LLC | 322,521 | $12.9M | 0.42% | +106,150+49.1% | Added |
| Invesco Ltd. | 340,613 | $13.6M | 0.00% | −2,018,821−85.6% | Reduced |
| Barclays PLC | 363,996 | $14.5M | 0.01% | +265,225+268.5% | Added |
| Sicart Associates LLC | 368,409 | $14.7M | 3.50% | −1,889−0.5% | Reduced |
| Nomura Holdings Inc | 377,728 | $15.0M | 0.12% | +377,728 | New |
| Stifel Financial Corp | 377,685 | $15.1M | 0.02% | −2,713−0.7% | Reduced |
| Bank of Montreal | 381,485 | $15.1M | 0.01% | +59,255+18.4% | Added |
| Susquehanna International Group, LLP | 380,466 | $15.2M | 0.02% | +292,195+331.0% | Added |
| TD Asset Management Inc | 421,864 | $15.7M | 0.02% | −2,715−0.6% | Reduced |