Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2021
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 338
- −24 vs. Q1 2021
- Shares held
- 124.4M
- +2.62M (+2.2%) vs. Q1 2021
- Total value
- $4.96B
- −$516.2M (−9.4%) vs. Q1 2021
- New holders
- 51
- 116 more added
- Sold out
- 75
- 103 more reduced
3 institutions that held it in Q1 2021 haven't filed for Q2 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2021
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Fifth Third Bancorp | 2,554 | $102.0K | 0.00% | −7,004−73.3% | Reduced |
| American International Group, Inc. | 2,868 | $114.0K | 0.00% | +633+28.3% | Added |
| Steward Partners Investment Advisory, LLC | 3,112 | $124.0K | 0.00% | −4,230−57.6% | Reduced |
| Carolinas Wealth Consulting LLC | 3,187 | $127.0K | 0.03% | −5,000−61.1% | Reduced |
| Advisors Asset Management, Inc. | 3,179 | $127.0K | 0.00% | −29−0.9% | Reduced |
| Leonteq Securities AG | 3,197 | $127.5K | 0.01% | +1,672+109.6% | Added |
| Semmax Financial Advisors Inc. | 3,786 | $151.0K | 0.05% | −242−6.0% | Reduced |
| Caldwell Trust Co | 4,000 | $159.6K | 0.02% | 00.0% | Unchanged |
| KB Financial Partners, LLC | 4,030 | $161.0K | 0.06% | +1,764+77.8% | Added |
| Federated Hermes, Inc. | 4,090 | $163.0K | 0.00% | +4,090 | New |
| Credit Agricole S A | 4,210 | $168.0K | 0.01% | 00.0% | Unchanged |
| Geneos Wealth Management Inc. | 4,704 | $187.0K | 0.01% | −423−8.3% | Reduced |
| Weiss Multi-Strategy Advisers LLC | 5,073 | $202.0K | 0.00% | +5,073 | New |
| Buckingham Strategic Wealth, LLC | 5,078 | $203.0K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 5,152 | $205.0K | 0.00% | −4,366−45.9% | Reduced |
| CIBC Asset Management Inc | 5,140 | $205.0K | 0.00% | 00.0% | Unchanged |
| Agf Investments Inc. | 5,238 | $209.0K | 0.00% | +5,238 | New |
| Global Retirement Partners, LLC | 5,313 | $212.0K | 0.02% | +702+15.2% | Added |
| Vident Investment Advisory, LLC | 5,587 | $223.0K | 0.01% | +5,587 | New |
| Icon Wealth Partners, LLC | 5,917 | $236.0K | 0.03% | +246+4.3% | Added |
| Wellington Management Group LLP | 5,911 | $236.0K | 0.00% | +5,911 | New |
| III Capital Management | 6,000 | $239.0K | 0.02% | +6,000 | New |
| ProVise Management Group, LLC | 6,111 | $244.0K | 0.02% | +307+5.3% | Added |
| Commerce Bank | 6,291 | $251.0K | 0.00% | −185−2.9% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 6,368 | $254.0K | 0.00% | −26,142−80.4% | Reduced |
| Mitchell & Pahl Private Wealth, LLC | 6,936 | $277.0K | 0.20% | −69−1.0% | Reduced |
| Hussman Strategic Advisors, Inc. | 7,200 | $287.0K | 0.06% | 00.0% | Unchanged |
| Baird Financial Group, Inc. | 7,396 | $295.0K | 0.00% | +369+5.3% | Added |
| Nomura Asset Management Co Ltd | 7,417 | $295.9K | 0.00% | −15,883−68.2% | Reduced |
| Wealthcare Advisory Partners LLC | 7,472 | $298.0K | 0.02% | +263+3.6% | Added |
| Northeast Financial Consultants Inc | 7,740 | $309.0K | 0.02% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 7,783 | $310.0K | 0.00% | −42,042−84.4% | Reduced |
| Bridgewater Associates, LP | 7,981 | $318.0K | 0.00% | +7,981 | New |
| Horizon Kinetics Asset Management LLC | 8,000 | $319.0K | 0.01% | 00.0% | Unchanged |
| Cetera Advisor Networks LLC | 8,217 | $328.0K | 0.00% | +8,217 | New |
| Kennedy Capital Management, Inc. | 8,329 | $332.0K | 0.01% | +321+4.0% | Added |
| USS Investment Management Ltd | 8,363 | $334.0K | 0.00% | 00.0% | Unchanged |
| FDx Advisors, Inc. | 8,376 | $334.0K | 0.01% | +658+8.5% | Added |
| Brandywine Managers, LLC | 8,460 | $337.0K | 0.38% | +1,375+19.4% | Added |
| Natixis | 8,530 | $340.0K | 0.00% | +2,871+50.7% | Added |
| Aigen Investment Management, LP | 8,912 | $355.0K | 0.06% | +8,912 | New |
| Metropolitan Life Insurance Co | 9,173 | $365.9K | 0.01% | +3,158+52.5% | Added |
| HighTower Advisors, LLC | 9,303 | $366.0K | 0.00% | −216−2.3% | Reduced |
| The PNC Financial Services Group, Inc. | 9,347 | $373.0K | 0.00% | −11−0.1% | Reduced |
| HSBC Holdings PLC | 9,435 | $376.0K | 0.00% | −4,980−34.5% | Reduced |
| Regions Financial Corp | 9,423 | $376.0K | 0.00% | +9,423 | New |
| Mackenzie Financial Corp | 9,783 | $390.0K | 0.00% | 00.0% | Unchanged |
| Maryland State Retirement & Pension System | 9,956 | $392.0K | 0.01% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 9,925 | $395.0K | 0.00% | −4,553−31.4% | Reduced |
| Waddell & Associates, LLC | 10,042 | $401.0K | 0.07% | +10,042 | New |
| Tower Research Capital LLC (TRC) | 10,183 | $406.0K | 0.01% | −2,140−17.4% | Reduced |
| Blair William & Co | 10,288 | $410.0K | 0.00% | −876−7.8% | Reduced |
| Nicollet Investment Management, Inc. | 10,504 | $419.0K | 0.17% | −307−2.8% | Reduced |
| Wrapmanager Inc | 10,583 | $422.0K | 0.11% | +71+0.7% | Added |
| Oppenheimer Asset Management Inc. | 10,717 | $427.0K | 0.01% | −219−2.0% | Reduced |
| Plancorp, LLC | 11,120 | $444.0K | 0.03% | +20+0.2% | Added |
| SG Americas Securities, LLC | 11,249 | $449.0K | 0.00% | −34,559−75.4% | Reduced |
| National Asset Management, Inc. | 11,206 | $454.0K | 0.01% | −1,792−13.8% | Reduced |
| Berkshire Asset Management LLC | 11,399 | $455.0K | 0.03% | −949−7.7% | Reduced |
| KBC Group NV | 11,811 | $471.0K | 0.00% | +300+2.6% | Added |
| SEI Investments Co | 14,052 | $492.0K | 0.00% | −13,410−48.8% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 12,817 | $511.0K | 0.00% | −8,404−39.6% | Reduced |
| Shell Asset Management Co | 13,169 | $525.0K | 0.01% | −32,964−71.5% | Reduced |
| Virtus ETF Advisers LLC | 13,212 | $527.0K | 0.22% | +128+1.0% | Added |
| AQR Capital Management LLC | 13,434 | $528.0K | 0.00% | +13,434 | New |
| Creative Planning | 13,320 | $531.0K | 0.00% | −30,859−69.8% | Reduced |
| Brown Advisory Securities, LLC | 13,500 | $539.0K | 0.08% | +8,025+146.6% | Added |
| Bank of Nova Scotia | 13,535 | $540.0K | 0.00% | +13,535 | New |
| Brookfield Asset Management Inc. | 13,568 | $541.0K | 0.00% | +13,568 | New |
| North Star Asset Management Inc | 13,753 | $549.0K | 0.03% | 00.0% | Unchanged |
| US Bancorp | 14,008 | $558.0K | 0.00% | +422+3.1% | Added |
| Victory Capital Management Inc | 14,216 | $567.0K | 0.00% | −12,034−45.8% | Reduced |
| Comerica Bank | 15,591 | $590.0K | 0.00% | −105−0.7% | Reduced |
| Lincoln National Corp | 15,070 | $601.0K | 0.01% | −395−2.6% | Reduced |
| Optimal Asset Management, Inc. | 15,118 | $603.0K | 0.07% | 00.0% | Unchanged |
| Castle Rock Wealth Management, LLC | 15,593 | $606.0K | 0.22% | 00.0% | Unchanged |
| Xponance, Inc. | 15,226 | $607.0K | 0.01% | +8,423+123.8% | Added |
| Arden Trust Co | 15,993 | $638.0K | 0.10% | −513−3.1% | Reduced |
| Tanaka Capital Management Inc | 16,661 | $665.0K | 0.90% | −3,950−19.2% | Reduced |
| State of Wisconsin Investment Board | 16,749 | $668.0K | 0.00% | −55,456−76.8% | Reduced |
| AGF Investments LLC | 17,289 | $690.0K | 0.07% | +17,289 | New |
| Teacher Retirement System of Texas | 17,518 | $699.0K | 0.00% | −10,438−37.3% | Reduced |
| Emerald Advisers, LLC | 17,621 | $703.0K | 0.03% | 00.0% | Unchanged |
| Alexandria Capital, LLC | 18,297 | $730.0K | 0.07% | +535+3.0% | Added |
| Natixis Advisors, L.P. | 18,864 | $752.0K | 0.00% | −1,740−8.4% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 19,274 | $769.0K | 0.00% | +4,397+29.6% | Added |
| AlphaCrest Capital Management LLC | 19,360 | $772.0K | 0.03% | +19,360 | New |
| Public Employees Retirement Association of Colorado | 19,604 | $782.0K | 0.00% | 00.0% | Unchanged |
| Allianz Asset Management GmbH | 19,710 | $786.0K | 0.00% | −15,134−43.4% | Reduced |
| Vestmark Advisory Solutions, Inc. | 19,887 | $793.0K | 0.06% | −6,622−25.0% | Reduced |
| Advisor Group Holdings, Inc. | 20,903 | $833.0K | 0.00% | +4,937+30.9% | Added |
| Grandfield & Dodd, LLC | 21,053 | $840.0K | 0.06% | +700+3.4% | Added |
| BNP Paribas Arbitrage, SA | 21,267 | $848.3K | 0.00% | −7,373−25.7% | Reduced |
| Simplex Trading, LLC | 21,354 | $851.0K | 0.03% | +20,579+2,655.4% | Added |
| Oppenheimer & Co Inc | 21,348 | $852.0K | 0.02% | +21,348 | New |
| MML Investors Services, LLC | 22,786 | $909.0K | 0.01% | +2,890+14.5% | Added |
| Kestra Advisory Services, LLC | 22,846 | $911.0K | 0.01% | −104−0.5% | Reduced |
| Private Advisor Group, LLC | 23,441 | $935.0K | 0.01% | +5,399+29.9% | Added |
| APG Asset Management N.V. | 28,200 | $949.0K | 0.00% | +28,200 | New |
| Profund Advisors LLC | 24,058 | $959.0K | 0.03% | −739−3.0% | Reduced |