Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 294
- +28 vs. Q1 2026
- Shares held
- 156.2M
- +8.88M (+6.0%) vs. Q1 2026
- Total value
- $4.00B
- +$1.18B (+41.8%) vs. Q1 2026
- New holders
- 56
- 120 more added
- Sold out
- 28
- 68 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rockefeller Capital Management L.P. | 8,894 | $228.8K | 0.00% | −17,041−65.7% | Reduced |
| Swiss Life Asset Management Ltd | 9,091 | $233.8K | 0.00% | +9,091 | New |
| The PNC Financial Services Group, Inc. | 9,122 | $234.6K | 0.00% | −98−1.1% | Reduced |
| Neuberger Berman Group LLC | 9,742 | $250.6K | 0.00% | +9,742 | New |
| HighTower Advisors, LLC | 11,020 | $283.4K | 0.00% | −951−7.9% | Reduced |
| Gilbert & Cook, Inc. | 11,179 | $287.5K | 0.03% | +308+2.8% | Added |
| Tower Research Capital LLC (TRC) | 11,393 | $293.0K | 0.01% | −9,585−45.7% | Reduced |
| Bayforest Capital Ltd | 11,437 | $294.2K | 0.27% | +11,370+16,970.1% | Added |
| Cetera Investment Advisers | 11,569 | $297.6K | 0.00% | +510+4.6% | Added |
| Pinnacle Wealth Planning Services, Inc. | 11,587 | $298.0K | 0.03% | +181+1.6% | Added |
| Lynx1 Capital Management LP | 11,658 | $299.8K | 0.03% | −1,868,645−99.4% | Reduced |
| CI Private Wealth, LLC | 11,704 | $301.0K | 0.00% | +11,704 | New |
| JustInvest LLC | 11,953 | $307.4K | 0.00% | +331+2.8% | Added |
| Atria Investments LLC | 12,130 | $312.0K | 0.00% | +18+0.1% | Added |
| Public Employees Retirement Association of Colorado | 12,238 | $315.0K | 0.00% | 00.0% | Unchanged |
| Pier 88 Investment Partners LLC | 12,700 | $326.6K | 0.08% | −52,100−80.4% | Reduced |
| National Asset Management, Inc. | 12,813 | $331.7K | 0.02% | +600+4.9% | Added |
| Ameritas Investment Partners, Inc. | 13,351 | $343.4K | 0.01% | +1,697+14.6% | Added |
| Great West Life Assurance Co | 13,434 | $345.0K | 0.00% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 13,585 | $349.4K | 0.01% | −5,357−28.3% | Reduced |
| Inceptionr LLC | 13,632 | $350.6K | 0.09% | +13,632 | New |
| Guggenheim Capital LLC | 13,636 | $350.7K | 0.00% | −189−1.4% | Reduced |
| LPL Financial LLC | 13,868 | $356.7K | 0.00% | +1,594+13.0% | Added |
| Royal Bank of Canada | 13,974 | $359.0K | 0.00% | +6,439+85.5% | Added |
| Winton Group Ltd | 14,100 | $362.7K | 0.01% | −57,079−80.2% | Reduced |
| Virginia Retirement Systems Et Al | 14,300 | $367.8K | 0.00% | +14,300 | New |
| Empowered Funds, LLC | 14,428 | $371.1K | 0.00% | −1,359−8.6% | Reduced |
| Xponance, Inc. | 14,616 | $375.9K | 0.00% | +1,376+10.4% | Added |
| Contravisory Investment Management, Inc. | 14,674 | $377.4K | 0.07% | +223+1.5% | Added |
| Breakwater Capital Group | 15,601 | $401.3K | 0.05% | +15+0.1% | Added |
| Graham Capital Management, L.P. | 15,669 | $403.0K | 0.01% | +15,669 | New |
| Teacher Retirement System of Texas | 15,713 | $404.1K | 0.00% | −2,169−12.1% | Reduced |
| Himension Fund | 15,949 | $410.2K | 0.03% | +15,949 | New |
| Mercer Global Advisors Inc | 16,257 | $418.1K | 0.00% | +16,257 | New |
| Wealth Enhancement Advisory Services, LLC | 16,467 | $422.9K | 0.00% | +16,467 | New |
| Intrust Bank NA | 16,477 | $423.8K | 0.03% | +2,138+14.9% | Added |
| Advisor Group Holdings, Inc. | 17,016 | $437.6K | 0.00% | +603+3.7% | Added |
| Victory Capital Management Inc | 17,197 | $442.3K | 0.00% | +1,003+6.2% | Added |
| Bellevue Group AG | 17,766 | $456.9K | 0.01% | 00.0% | Unchanged |
| State of Wyoming | 17,778 | $457.3K | 0.05% | +17,778 | New |
| Fieldview Capital Management, LLC | 17,873 | $459.7K | 0.13% | +17,873 | New |
| Banque Cantonale Vaudoise | 17,926 | $461.0K | 0.02% | +17,926 | New |
| Martingale Asset Management L P | 18,530 | $476.6K | 0.01% | −50.0% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 18,556 | $477.3K | 0.00% | +18,556 | New |
| Allstate Corp | 19,313 | $496.7K | 0.00% | +19,313 | New |
| Ieq Capital, LLC | 20,185 | $519.2K | 0.00% | +20,185 | New |
| Capstone Investment Advisors, LLC | 20,964 | $539.2K | 0.00% | +8,001+61.7% | Added |
| Cerity Partners LLC | 21,587 | $555.2K | 0.00% | +8,929+70.5% | Added |
| Simplex Trading, LLC | 23,952 | $616.0K | 0.02% | +11,637+94.5% | Added |
| ProShare Advisors LLC | 24,466 | $629.3K | 0.00% | −3,271−11.8% | Reduced |
| BNP Paribas Arbitrage, SA | 25,071 | $644.8K | 0.00% | −14,822−37.2% | Reduced |
| Erste Asset Management GmbH | 26,900 | $696.4K | 0.01% | 00.0% | Unchanged |
| SBI Okasan Asset Management Co.Ltd. | 29,500 | $763.8K | 0.03% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 29,819 | $766.9K | 0.05% | −10,824−26.6% | Reduced |
| KLP Kapitalforvaltning AS | 30,900 | $794.7K | 0.00% | 00.0% | Unchanged |
| J. Safra Sarasin Holding AG | 31,250 | $804.0K | 0.01% | +31,250 | New |
| Yorktown Management & Research Co Inc | 32,100 | $825.6K | 0.51% | +32,100 | New |
| Thrivent Financial for Lutherans | 32,555 | $837.0K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 32,799 | $843.6K | 0.00% | +14,668+80.9% | Added |
| State Board of Administration of Florida Retirement System | 34,168 | $878.8K | 0.00% | 00.0% | Unchanged |
| Jefferies Financial Group Inc. | 34,425 | $885.4K | 0.01% | 00.0% | Unchanged |
| Intech Investment Management LLC | 35,484 | $912.6K | 0.01% | −3,447−8.9% | Reduced |
| Nomura Asset Management Co Ltd | 36,732 | $944.7K | 0.00% | 00.0% | Unchanged |
| Arizona State Retirement System | 37,196 | $956.7K | 0.00% | −957−2.5% | Reduced |
| Vanguard Investments Australia, Ltd. | 37,410 | $962.2K | 0.00% | 00.0% | Unchanged |
| Quantinno Capital Management LP | 37,651 | $968.4K | 0.00% | +7,481+24.8% | Added |
| Jain Global LLC | 38,435 | $988.5K | 0.01% | +38,435 | New |
| Tudor Investment Corp Et Al | 40,965 | $1.05M | 0.00% | +40,965 | New |
| SG Americas Securities, LLC | 42,339 | $1.09M | 0.00% | −4,303−9.2% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 43,387 | $1.12M | 0.01% | +4,842+12.6% | Added |
| State of New Jersey Common Pension Fund D | 43,587 | $1.12M | 0.00% | −3,884−8.2% | Reduced |
| Raymond James Financial Inc | 43,744 | $1.13M | 0.00% | +9,361+27.2% | Added |
| DekaBank Deutsche Girozentrale | 59,800 | $1.13M | 0.00% | 00.0% | Unchanged |
| Employees Retirement System of Texas | 44,340 | $1.14M | 0.01% | −2,837−6.0% | Reduced |
| Savvy Advisors, Inc. | 45,194 | $1.16M | 0.02% | +45,194 | New |
| Voya Investment Management LLC | 45,823 | $1.18M | 0.00% | +22,151+93.6% | Added |
| MAI Capital Management | 49,160 | $1.26M | 0.00% | +2,570+5.5% | Added |
| Profund Advisors LLC | 49,899 | $1.28M | 0.04% | −18,328−26.9% | Reduced |
| Envestnet Asset Management Inc | 51,424 | $1.32M | 0.00% | +524+1.0% | Added |
| Ironwood Investment Management LLC | 52,080 | $1.34M | 0.46% | +180.0% | Added |
| Wellington Management Group LLP | 52,618 | $1.35M | 0.00% | −745−1.4% | Reduced |
| Virtus Investment Advisers, Inc. | 53,688 | $1.38M | 0.32% | +38,522+254.0% | Added |
| Pathstone Holdings, LLC | 54,014 | $1.39M | 0.00% | −2,311−4.1% | Reduced |
| Franklin Resources Inc | 56,662 | $1.46M | 0.00% | +7,930+16.3% | Added |
| Engineers Gate Manager LP | 57,430 | $1.48M | 0.02% | +41,320+256.5% | Added |
| Prudential Financial Inc | 58,135 | $1.50M | 0.00% | +27,565+90.2% | Added |
| SEI Investments Co | 58,989 | $1.52M | 0.00% | +6,754+12.9% | Added |
| Handelsbanken Fonder AB | 59,600 | $1.53M | 0.00% | +15,800+36.1% | Added |
| Dana Investment Advisors, Inc. | 59,971 | $1.54M | 0.04% | +8,049+15.5% | Added |
| Jupiter Topco LLC | 60,028 | $1.54M | 0.00% | +60,028 | New |
| Vanguard Global Advisers, LLC | 61,400 | $1.58M | 0.00% | +2,621+4.5% | Added |
| 1492 Capital Management LLC | 66,368 | $1.71M | 0.50% | −1,049−1.6% | Reduced |
| Citadel Advisors LLC | 66,971 | $1.72M | 0.00% | −114,446−63.1% | Reduced |
| Knights of Columbus Asset Advisors LLC | 67,591 | $1.74M | 0.09% | +11,262+20.0% | Added |
| Phocas Financial Corp. | 71,197 | $1.83M | 0.25% | +71,197 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 78,937 | $2.03M | 0.00% | −16,256−17.1% | Reduced |
| Ameriprise Financial Inc | 82,650 | $2.13M | 0.00% | −6,884−7.7% | Reduced |
| Creative Planning | 84,644 | $2.18M | 0.00% | +10,575+14.3% | Added |
| State of Wisconsin Investment Board | 84,652 | $2.18M | 0.00% | +2,295+2.8% | Added |
| Barclays PLC | 84,892 | $2.18M | 0.00% | +32,808+63.0% | Added |