Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 269
- +25 vs. Q4 2025
- Shares held
- 147.4M
- +14.8M (+11.2%) vs. Q4 2025
- Total value
- $2.82B
- +$631.6M (+28.8%) vs. Q4 2025
- New holders
- 55
- 104 more added
- Sold out
- 30
- 58 more reduced
6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avion Wealth | 40 | $0 | 0.00% | 00.0% | Unchanged |
| Raffa Wealth Management, LLC | 1 | $19 | 0.00% | +1 | New |
| Vermillion Wealth Management, Inc. | 1 | $19 | 0.00% | +1 | New |
| Curio Wealth, LLC | 1 | $19 | 0.00% | +1 | New |
| DiNuzzo Private Wealth, Inc. | 2 | $39 | 0.00% | +2 | New |
| Dunhill Financial, LLC | 2 | $40 | 0.00% | 00.0% | Unchanged |
| HFM Investment Advisors, LLC | 5 | $96 | 0.00% | −4−44.4% | Reduced |
| Rialto Wealth Management, LLC | 5 | $96 | 0.00% | −3−37.5% | Reduced |
| Bay Harbor Wealth Management, LLC | 6 | $115 | 0.00% | +3+100.0% | Added |
| JFS Wealth Advisors, LLC | 8 | $154 | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 9 | $173 | 0.00% | 00.0% | Unchanged |
| Atlantic Private Wealth, LLC | 10 | $192 | 0.00% | 00.0% | Unchanged |
| Cullen/Frost Bankers, Inc. | 10 | $192 | 0.00% | +10 | New |
| SJS Investment Consulting Inc. | 16 | $308 | 0.00% | +12+300.0% | Added |
| Basecamp Wealth Advisors LLC | 17 | $326 | 0.00% | −14−45.2% | Reduced |
| Sunbelt Securities, Inc. | 22 | $422 | 0.00% | 00.0% | Unchanged |
| Keating Financial Advisory Services, Inc. | 33 | $634 | 0.00% | +13+65.0% | Added |
| Cornerstone Financial Management LLC | 34 | $653 | 0.00% | 00.0% | Unchanged |
| Fortitude Family Office, LLC | 35 | $672 | 0.00% | +28+400.0% | Added |
| Manchester Capital Management LLC | 36 | $692 | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 39 | $708 | 0.00% | +39 | New |
| Bell Investment Advisors, Inc | 38 | $730 | 0.00% | 00.0% | Unchanged |
| Ronald Blue Trust, Inc. | 40 | $768 | 0.00% | 00.0% | Unchanged |
| Transamerica Financial Advisors, Inc. | 40 | $768 | 0.00% | +40 | New |
| Wealth Preservation Advisors, LLC | 43 | $826 | 0.00% | +43 | New |
| Essential Partners LLC | 45 | $864 | 0.00% | +45 | New |
| Hantz Financial Services, Inc. | 57 | $1.00K | 0.00% | 00.0% | Unchanged |
| True Wealth Design, LLC | 57 | $1.09K | 0.00% | +1+1.8% | Added |
| Larson Financial Group LLC | 62 | $1.19K | 0.00% | +24+63.2% | Added |
| CVA Family Office, LLC | 63 | $1.21K | 0.00% | +63 | New |
| WPG Advisers, LLC | 66 | $1.27K | 0.00% | +66 | New |
| Rossby Financial, LCC | 65 | $1.28K | 0.00% | +65 | New |
| Bayforest Capital Ltd | 67 | $1.29K | 0.00% | −20,366−99.7% | Reduced |
| TD Private Client Wealth LLC | 71 | $1.36K | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 76 | $1.46K | 0.00% | 00.0% | Unchanged |
| Johnson Financial Group, Inc. | 81 | $1.56K | 0.00% | 00.0% | Unchanged |
| Your Advocates Ltd., LLP | 100 | $1.92K | 0.00% | 00.0% | Unchanged |
| Golden State Equity Partners | 130 | $2.50K | 0.00% | +130 | New |
| Steward Partners Investment Advisory, LLC | 136 | $2.61K | 0.00% | +136 | New |
| Massmutual Trust Co FSB | 143 | $2.75K | 0.00% | 00.0% | Unchanged |
| Aster Capital Management (DIFC) Ltd | 246 | $3.34K | 0.00% | −3,205−92.9% | Reduced |
| Root Financial Partners, LLC | 188 | $3.61K | 0.00% | +88+88.0% | Added |
| Parkside Financial Bank & Trust | 189 | $3.63K | 0.00% | 00.0% | Unchanged |
| Comprehensive Financial Planning, Inc. | 200 | $3.84K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 241 | $4.63K | 0.00% | +11+4.8% | Added |
| City State Bank | 250 | $4.80K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 256 | $4.91K | 0.00% | +49+23.7% | Added |
| Farther Finance Advisors, LLC | 255 | $5.02K | 0.00% | +53+26.2% | Added |
| Allworth Financial LP | 280 | $5.38K | 0.00% | +190+211.1% | Added |
| Eastern Bank | 282 | $5.41K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 288 | $5.53K | 0.00% | +93+47.7% | Added |
| Private Wealth Management Group, LLC | 296 | $5.68K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 301 | $5.80K | 0.00% | +103+52.0% | Added |
| Covestor Ltd | 322 | $6.00K | 0.00% | −257−44.4% | Reduced |
| Parallel Advisors, LLC | 358 | $6.87K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 368 | $7.07K | 0.00% | −854−69.9% | Reduced |
| GWM Advisors LLC | 400 | $7.68K | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 420 | $8.06K | 0.00% | −71−14.5% | Reduced |
| Owl Creek Wealth Partners LLC | 450 | $8.64K | 0.00% | +450 | New |
| Mowery & Schoenfeld Wealth Management, LLC | 500 | $9.60K | 0.01% | +500 | New |
| Quantbot Technologies LP | 512 | $9.83K | 0.00% | +512 | New |
| Umb Bank N A | 624 | $12.0K | 0.00% | +362+138.2% | Added |
| Nemes Rush Group LLC | 700 | $13.4K | 0.00% | 00.0% | Unchanged |
| Quadrant Capital Group LLC | 758 | $14.6K | 0.00% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 848 | $16.3K | 0.00% | +848 | New |
| Optiver Holding B.V. | 866 | $16.6K | 0.00% | +457+111.7% | Added |
| US Bancorp | 902 | $17.3K | 0.00% | +68+8.2% | Added |
| Los Angeles Capital Management LLC | 927 | $17.8K | 0.00% | +300+47.8% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 1,001 | $19.2K | 0.00% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 1,107 | $20.0K | 0.00% | −206−15.7% | Reduced |
| Kemnay Advisory Services Inc. | 1,134 | $21.8K | 0.00% | +1,134 | New |
| GAMMA Investing LLC | 1,428 | $27.4K | 0.00% | +466+48.4% | Added |
| Bartlett & Co. Wealth Management LLC | 1,500 | $28.0K | 0.00% | 00.0% | Unchanged |
| Versant Capital Management, Inc | 1,476 | $28.3K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 2,424 | $46.5K | 0.00% | +975+67.3% | Added |
| Fifth Third Bancorp | 2,847 | $54.7K | 0.00% | +2,847 | New |
| GF Fund Management Co. Ltd. | 3,294 | $63.2K | 0.00% | +413+14.3% | Added |
| Sterling Capital Management LLC | 4,493 | $86.3K | 0.00% | −2,745−37.9% | Reduced |
| CWM, LLC | 4,651 | $89.3K | 0.00% | +2,045+78.5% | Added |
| Eurizon Capital SGR S.p.A. | 5,045 | $91.7K | 0.00% | 00.0% | Unchanged |
| KBC Group NV | 4,943 | $95.0K | 0.00% | −1,325−21.1% | Reduced |
| Assetmark, Inc | 5,199 | $99.8K | 0.00% | +12+0.2% | Added |
| Royal Bank of Canada | 7,535 | $145.0K | 0.00% | −3,800−33.5% | Reduced |
| NBC Securities, Inc. | 7,617 | $146.2K | 0.01% | +1,081+16.5% | Added |
| Mirae Asset Global Investments Co., Ltd. | 8,272 | $158.8K | 0.00% | +1,145+16.1% | Added |
| The PNC Financial Services Group, Inc. | 9,220 | $177.0K | 0.00% | +739+8.7% | Added |
| Headlands Technologies LLC | 10,557 | $202.7K | 0.02% | −35,826−77.2% | Reduced |
| Gilbert & Cook, Inc. | 10,871 | $208.7K | 0.03% | +10,871 | New |
| DnB Asset Management AS | 10,959 | $210.4K | 0.00% | +10,959 | New |
| Cetera Investment Advisers | 11,059 | $212.3K | 0.00% | +11,059 | New |
| Pinnacle Wealth Planning Services, Inc. | 11,406 | $219.0K | 0.02% | +8,449+285.7% | Added |
| National Asset Management, Inc. | 12,213 | $220.8K | 0.01% | +12,213 | New |
| JustInvest LLC | 11,622 | $223.1K | 0.00% | −114−1.0% | Reduced |
| Ameritas Investment Partners, Inc. | 11,654 | $223.8K | 0.01% | +589+5.3% | Added |
| HighTower Advisors, LLC | 11,971 | $229.8K | 0.00% | +214+1.8% | Added |
| Atria Investments LLC | 12,112 | $232.6K | 0.00% | +12,112 | New |
| Public Employees Retirement Association of Colorado | 12,238 | $235.0K | 0.00% | 00.0% | Unchanged |
| LPL Financial LLC | 12,274 | $235.7K | 0.00% | +1,770+16.9% | Added |
| Simplex Trading, LLC | 12,315 | $236.4K | 0.01% | +12,315 | New |
| Cerity Partners LLC | 12,658 | $243.0K | 0.00% | +12,658 | New |