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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

Q1 2026 vs. Q4 2025

How the institutions holding Denali Therapeutics Inc. changed between Q4 2025 and Q1 2026.

All holders in Q1 2026All holders in Q4 2025

13F holders of DNLI: Q4 2025 compared with Q1 2026
MeasureQ4 2025Of which not filed for Q1 2026Q1 2026Change
Holders2506269+25
Shares151.1M18.5M147.4M+14.8M (+11.2%)
Value$2.50B$306.2M$2.82B+$631.6M (+28.8%)

6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (55)

Institutions that held Denali Therapeutics Inc. at the end of Q1 2026 but not at the end of Q4 2025.

Institutions new to DNLI in Q1 2026
InstitutionSharesValue% of portfolio
Vanguard Capital Management LLC6,147,957$118.0M0.00%
Vanguard Portfolio Management LLC6,120,160$117.5M0.01%
Artisan Partners Limited Partnership1,099,719$21.1M0.03%
Vanguard Fiduciary Trust Co949,695$18.2M0.00%
Clearstead Advisors, LLC737,990$14.2M0.13%
Braidwell LP296,324$5.69M0.19%
Privium Fund Management B.V.254,857$4.89M1.02%
Great Lakes Advisors, LLC227,110$4.36M0.04%
Balyasny Asset Management LLC195,108$3.75M0.01%
Sector Gamma AS162,710$3.12M0.74%
Vanguard Asset Management, Ltd125,243$2.40M0.00%
Lumbard & Kellner, LLC94,782$1.82M0.63%
XTX Topco Ltd78,567$1.51M0.03%
Vanguard Global Advisers, LLC58,779$1.13M0.00%
SEI Investments Co52,235$1.00M0.00%
Virtu Financial LLC43,362$833.0K0.03%
Vanguard Investments Australia, Ltd.37,410$718.3K0.00%
Nomura Asset Management Co Ltd36,732$705.3K0.00%
Seven Fleet Capital Management LP35,286$677.5K0.21%
Jefferies Financial Group Inc.34,425$661.0K0.01%
Prudential Financial Inc30,570$586.9K0.00%
Twinbeech Capital LP23,000$441.6K0.05%
E Fund Management Co., Ltd.18,942$363.7K0.01%
Amundi18,604$357.2K0.00%
Mariner, LLC18,131$348.1K0.00%
Engineers Gate Manager LP16,110$309.3K0.00%
Caitong International Asset Management Co., Ltd15,861$304.5K0.06%
Contravisory Investment Management, Inc.14,451$277.5K0.06%
Cerity Partners LLC12,658$243.0K0.00%
Simplex Trading, LLC12,315$236.4K0.01%
Atria Investments LLC12,112$232.6K0.00%
National Asset Management, Inc.12,213$220.8K0.01%
Cetera Investment Advisers11,059$212.3K0.00%
DnB Asset Management AS10,959$210.4K0.00%
Gilbert & Cook, Inc.10,871$208.7K0.03%
Fifth Third Bancorp2,847$54.7K0.00%
Kemnay Advisory Services Inc.1,134$21.8K0.00%
Advisory Services Network, LLC848$16.3K0.00%
Quantbot Technologies LP512$9.83K0.00%
Mowery & Schoenfeld Wealth Management, LLC500$9.60K0.01%
Owl Creek Wealth Partners LLC450$8.64K0.00%
Steward Partners Investment Advisory, LLC136$2.61K0.00%
Golden State Equity Partners130$2.50K0.00%
Rossby Financial, LCC65$1.28K0.00%
WPG Advisers, LLC66$1.27K0.00%
CVA Family Office, LLC63$1.21K0.00%
Essential Partners LLC45$8640.00%
Wealth Preservation Advisors, LLC43$8260.00%
Transamerica Financial Advisors, Inc.40$7680.00%
Jones Financial Companies LLLP39$7080.00%
Cullen/Frost Bankers, Inc.10$1920.00%
DiNuzzo Private Wealth, Inc.2$390.00%
Raffa Wealth Management, LLC1$190.00%
Vermillion Wealth Management, Inc.1$190.00%
Curio Wealth, LLC1$190.00%

Sold out (30)

Institutions that held Denali Therapeutics Inc. at the end of Q4 2025 and filed for Q1 2026 without it.

Not filed for Q1 2026 yet (6)

Institutions that held Denali Therapeutics Inc. at the end of Q4 2025 and haven't filed a 13F for Q1 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding DNLI in Q4 2025 that haven't filed for Q1 2026
InstitutionShares, Q4 2025Value, Q4 2025
Vanguard Group Inc13,057,890$215.6M
Norges Bank5,119,622$84.5M
Clarius Group, LLC368,995$6.09M
Comerica Bank1,284$21.2K
ORG Partners LLC130$2.15K
Global Retirement Partners, LLC1$17