Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2024
Institutional positions in Xenon Pharmaceuticals Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 209
- +8 vs. Q3 2024
- Shares held
- 76.3M
- +1.44M (+1.9%) vs. Q3 2024
- Total value
- $2.99B
- +$42.4M (+1.4%) vs. Q3 2024
- New holders
- 29
- 66 more added
- Sold out
- 21
- 69 more reduced
2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Prudential Financial Inc | 39,000 | $1.53M | 0.00% | +24,956+177.7% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 40,376 | $1.56M | 0.01% | 00.0% | Unchanged |
| Woodline Partners LP | 39,938 | $1.57M | 0.01% | +39,938 | New |
| Artia Global Partners LP | 40,000 | $1.57M | 0.63% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 46,597 | $1.83M | 0.00% | −2,294−4.7% | Reduced |
| Envestnet Asset Management Inc | 47,297 | $1.85M | 0.00% | −1,539−3.2% | Reduced |
| LMR Partners LLP | 48,668 | $1.91M | 0.03% | 00.0% | Unchanged |
| Erste Asset Management GmbH | 50,000 | $1.94M | 0.02% | 00.0% | Unchanged |
| Harbor Capital Advisors, Inc. | 49,818 | $1.95M | 0.09% | +1,755+3.7% | Added |
| ADAR1 Capital Management, LLC | 50,547 | $1.98M | 0.41% | +22,644+81.2% | Added |
| Sphera Funds Management Ltd. | 52,097 | $2.04M | 0.38% | +52,097 | New |
| Deutsche Bank AG | 53,711 | $2.11M | 0.00% | 00.0% | Unchanged |
| BIT Capital GmbH | 53,928 | $2.11M | 0.19% | +53,928 | New |
| State of New Jersey Common Pension Fund D | 54,033 | $2.12M | 0.01% | +5,460+11.2% | Added |
| Moore Capital Management, LP | 55,000 | $2.16M | 0.04% | 00.0% | Unchanged |
| California State Teachers Retirement System | 55,492 | $2.18M | 0.00% | −512−0.9% | Reduced |
| Wells Fargo & Company | 59,520 | $2.33M | 0.00% | −936−1.5% | Reduced |
| Royal Bank of Canada | 60,068 | $2.35M | 0.00% | +22,432+59.6% | Added |
| Legal & General Group Plc | 60,406 | $2.37M | 0.00% | +5,286+9.6% | Added |
| Alps Advisors Inc | 61,648 | $2.42M | 0.02% | +4,659+8.2% | Added |
| Ikarian Capital, LLC | 62,052 | $2.43M | 0.69% | −45,135−42.1% | Reduced |
| Voya Investment Management LLC | 62,415 | $2.45M | 0.00% | +15,250+32.3% | Added |
| Northern Trust Corp | 65,783 | $2.58M | 0.00% | +22,377+51.6% | Added |
| HighVista Strategies LLC | 66,788 | $2.62M | 0.97% | −6,974−9.5% | Reduced |
| Morgan Stanley | 68,062 | $2.67M | 0.00% | −171,880−71.6% | Reduced |
| ExodusPoint Capital Management, LP | 68,884 | $2.70M | 0.03% | −193,747−73.8% | Reduced |
| Geode Capital Management, LLC | 69,529 | $2.73M | 0.00% | +720+1.0% | Added |
| Atika Capital Management LLC | 72,600 | $2.85M | 0.37% | −53,400−42.4% | Reduced |
| D. E. Shaw & Co., Inc. | 86,973 | $3.41M | 0.00% | −117,919−57.6% | Reduced |
| Ameriprise Financial Inc | 92,350 | $3.62M | 0.00% | +25,967+39.1% | Added |
| Neuberger Berman Group LLC | 92,961 | $3.64M | 0.00% | +92,961 | New |
| State of Wisconsin Investment Board | 96,584 | $3.79M | 0.01% | −4,398−4.4% | Reduced |
| Bamco Inc | 100,100 | $3.92M | 0.01% | 00.0% | Unchanged |
| Nan Fung Group Holdings Ltd | 106,680 | $4.18M | 3.58% | 00.0% | Unchanged |
| Bank of America Corp | 106,906 | $4.19M | 0.00% | −20,550−16.1% | Reduced |
| PFM Health Sciences, LP | 116,998 | $4.59M | 0.35% | −62,880−35.0% | Reduced |
| Swiss National Bank | 126,600 | $4.96M | 0.00% | +1,300+1.0% | Added |
| Ally Bridge Group (NY) LLC | 129,291 | $5.07M | 4.35% | −82,500−39.0% | Reduced |
| New York State Common Retirement Fund | 132,521 | $5.19M | 0.01% | 00.0% | Unchanged |
| Bridger Management, LLC | 146,800 | $5.75M | 3.09% | 00.0% | Unchanged |
| Eversept Partners, LP | 155,540 | $6.10M | 0.63% | +155,540 | New |
| Deep Track Capital, LP | 169,132 | $6.63M | 0.25% | +169,132 | New |
| Schroder Investment Management Group | 176,674 | $6.81M | 0.01% | 00.0% | Unchanged |
| Granahan Investment Management Inc | 182,333 | $7.15M | 0.30% | −18,544−9.2% | Reduced |
| Balyasny Asset Management LLC | 184,580 | $7.24M | 0.02% | +100,382+119.2% | Added |
| AXA S.A. | 187,796 | $7.36M | 0.02% | −294−0.2% | Reduced |
| UBS Asset Management Americas Inc | 191,852 | $7.52M | 0.00% | +29,169+17.9% | Added |
| Parkman Healthcare Partners LLC | 193,004 | $7.57M | 1.01% | +1,346+0.7% | Added |
| Lord, Abbett & Co. LLC | 194,971 | $7.64M | 0.02% | +20,986+12.1% | Added |
| MPM Oncology Impact Management LP | 197,212 | $7.73M | 1.10% | +31,412+18.9% | Added |
| DnB Asset Management AS | 203,243 | $7.97M | 0.03% | +12,620+6.6% | Added |
| Invesco Ltd. | 209,554 | $8.21M | 0.00% | −6,268−2.9% | Reduced |
| Russell Investments Group, Ltd. | 213,696 | $8.38M | 0.01% | −9,918−4.4% | Reduced |
| Walleye Capital LLC | 221,982 | $8.70M | 0.08% | +117,022+111.5% | Added |
| Assenagon Asset Management S.A. | 238,522 | $9.35M | 0.02% | +26,235+12.4% | Added |
| Algert Global LLC | 241,417 | $9.46M | 0.22% | +21,772+9.9% | Added |
| Great Point Partners LLC | 245,272 | $9.61M | 4.53% | +245,272 | New |
| Dimensional Fund Advisors LP | 259,970 | $10.2M | 0.00% | −39,895−13.3% | Reduced |
| Two Sigma Investments, LP | 273,352 | $10.7M | 0.02% | +29,773+12.2% | Added |
| DAFNA Capital Management LLC | 273,739 | $10.7M | 2.73% | 00.0% | Unchanged |
| Standard Life Aberdeen plc | 283,899 | $11.1M | 0.02% | +35,588+14.3% | Added |
| Altium Capital Management LP | 288,000 | $11.3M | 3.52% | −72,600−20.1% | Reduced |
| State Street Corp | 288,722 | $11.3M | 0.00% | +9,209+3.3% | Added |
| Alyeska Investment Group, L.P. | 288,843 | $11.3M | 0.04% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 298,700 | $11.7M | 0.03% | +25,000+9.1% | Added |
| Saturn V Capital Management LLC | 322,470 | $12.6M | 4.95% | +322,470 | New |
| Perceptive Advisors LLC | 325,324 | $12.8M | 0.36% | −199,606−38.0% | Reduced |
| Citadel Advisors LLC | 327,303 | $12.8M | 0.01% | −395,201−54.7% | Reduced |
| Vanguard Group Inc | 342,779 | $13.4M | 0.00% | −1,586−0.5% | Reduced |
| Millennium Management LLC | 346,040 | $13.6M | 0.01% | +137,014+65.5% | Added |
| StemPoint Capital LP | 375,845 | $14.7M | 3.70% | +375,845 | New |
| Goldman Sachs Group Inc | 410,246 | $16.1M | 0.00% | −49,379−10.7% | Reduced |
| Avidity Partners Management LP | 474,000 | $18.6M | 1.85% | −344,000−42.1% | Reduced |
| Candriam Luxembourg S.C.A. | 492,181 | $19.3M | 0.11% | +28,320+6.1% | Added |
| Fiera Capital Corp | 535,887 | $21.0M | 0.07% | −18,313−3.3% | Reduced |
| Federated Hermes, Inc. | 558,500 | $21.9M | 0.05% | −177,700−24.1% | Reduced |
| Franklin Resources Inc | 575,590 | $22.6M | 0.01% | +9,675+1.7% | Added |
| Boxer Capital Management, LLC | 600,000 | $23.5M | 2.00% | +600,000 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 663,704 | $26.0M | 0.06% | +224,630+51.2% | Added |
| First Turn Management, LLC | 684,986 | $26.9M | 4.81% | +359,768+110.6% | Added |
| Loomis Sayles & Co L P | 687,145 | $26.9M | 0.03% | −20,077−2.8% | Reduced |
| Siren, L.L.C. | 743,769 | $29.2M | 1.29% | 00.0% | Unchanged |
| Jennison Associates LLC | 801,553 | $31.4M | 0.02% | +224,892+39.0% | Added |
| Vestal Point Capital, LP | 810,000 | $31.8M | 1.88% | −15,000−1.8% | Reduced |
| TimesSquare Capital Management, LLC | 848,850 | $33.3M | 0.48% | +70,557+9.1% | Added |
| Marshall Wace, LLP | 899,718 | $35.3M | 0.04% | −295,762−24.7% | Reduced |
| OrbiMed Advisors LLC | 947,877 | $37.2M | 0.77% | +36,457+4.0% | Added |
| Baker Bros. Advisors LP | 993,679 | $39.0M | 0.42% | 00.0% | Unchanged |
| Samlyn Capital, LLC | 1,017,838 | $39.9M | 0.63% | −2,368−0.2% | Reduced |
| Westfield Capital Management Co LP | 1,157,189 | $45.4M | 0.20% | +487,589+72.8% | Added |
| First Light Asset Management, LLC | 1,160,580 | $45.5M | 4.35% | −21,082−1.8% | Reduced |
| Affinity Asset Advisors, LLC | 1,161,237 | $45.5M | 7.11% | +17,216+1.5% | Added |
| Rock Springs Capital Management LP | 1,251,859 | $49.1M | 1.87% | −64,618−4.9% | Reduced |
| JPMorgan Chase & Co | 1,356,895 | $53.2M | 0.00% | +380,112+38.9% | Added |
| T. Rowe Price Investment Management, Inc. | 1,437,831 | $56.4M | 0.03% | −65,977−4.4% | Reduced |
| Alliancebernstein L.P. | 1,443,180 | $56.6M | 0.02% | +18,445+1.3% | Added |
| Pictet Asset Management Holding SA | 1,496,511 | $58.7M | 0.06% | −32,303−2.1% | Reduced |
| Adage Capital Partners GP, L.L.C. | 1,863,473 | $73.0M | 0.13% | −220,499−10.6% | Reduced |
| BlackRock, Inc. | 2,105,236 | $82.5M | 0.00% | −3260.0% | Reduced |
| Capital World Investors | 2,294,537 | $89.9M | 0.01% | −387,000−14.4% | Reduced |