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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 2 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2024

Institutional positions in Xenon Pharmaceuticals Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
220
+17 vs. Q4 2023
Shares held
73.5M
+1.65M (+2.3%) vs. Q4 2023
Total value
$3.16B
−$145.6M (−4.4%) vs. Q4 2023
New holders
36
80 more added
Sold out
19
66 more reduced

1 institution that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 220 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ1 2024: $3.16B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q4 2023.

Institutions holding XENE in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
LMR Partners LLP48,668$2.10M0.05%+47,710+4,980.2%Added
Northern Trust Corp48,470$2.09M0.00%−13,501−21.8%Reduced
Envestnet Asset Management Inc48,177$2.07M0.00%+2,948+6.5%Added
Trexquant Investment LP46,874$2.02M0.04%+46,874New
Jump Financial, LLC46,079$1.98M0.05%+22,079+92.0%Added
Qube Research & Technologies Ltd45,286$1.95M0.00%+45,286New
Nuveen Asset Management, LLC42,473$1.83M0.00%+2,109+5.2%Added
Artia Global Partners LP40,000$1.72M0.42%+40,000New
DekaBank Deutsche Girozentrale39,000$1.67M0.00%00.0%Unchanged
Deutsche Bank AG38,711$1.67M0.00%+36,216+1,451.5%Added
CIBC World Markets Inc.37,320$1.61M0.00%−572−1.5%Reduced
JPMorgan Chase & Co36,621$1.58M0.00%−16,167−30.6%Reduced
UBS Group AG36,246$1.56M0.00%+5,303+17.1%Added
Royal Bank of Canada35,132$1.51M0.00%−923−2.6%Reduced
TLS Advisors LLC32,956$1.42M3.51%00.0%Unchanged
HRT Financial LP32,608$1.40M0.01%−50,461−60.7%Reduced
Standard Life Aberdeen plc32,036$1.38M0.00%00.0%Unchanged
Cinctive Capital Management LP31,770$1.37M0.07%+4,170+15.1%Added
Zurcher Kantonalbank (Zurich Cantonalbank)31,280$1.35M0.00%+15,696+100.7%Added
Boothbay Fund Management, LLC30,361$1.31M0.04%−9,895−24.6%Reduced
Engineers Gate Manager LP26,513$1.14M0.03%+26,513New
Tudor Investment Corp Et Al25,157$1.08M0.01%−18,064−41.8%Reduced
NJ State Employees Deferred Compensation Plan25,000$1.08M0.14%00.0%Unchanged
Aquatic Capital Management LLC24,700$1.06M0.03%+5,200+26.7%Added
Knott David M Jr23,866$1.03M0.36%00.0%Unchanged
Rathbone Brothers plc23,666$1.02M0.01%00.0%Unchanged
Susquehanna International Group, LLP23,646$1.02M0.00%−29,305−55.3%Reduced
Stifel Financial Corp22,175$954.6K0.00%+1,294+6.2%Added
Gsa Capital Partners LLP21,614$930.0K0.07%+21,614New
Sanders Morris Harris LLC21,500$925.6K0.17%00.0%Unchanged
Chartwell Investment Partners, LLC21,020$905.0K0.03%+500+2.4%Added
TD Asset Management Inc20,430$879.5K0.00%+4,200+25.9%Added
SG Americas Securities, LLC20,366$877.0K0.00%+1,760+9.5%Added
Natixis Advisors, L.P.19,676$847.0K0.00%−1,617−7.6%Reduced
Prelude Capital Management, LLC18,311$788.3K0.05%−13,885−43.1%Reduced
Y-Intercept (Hong Kong) Ltd18,305$788.0K0.06%+18,305New
Allianz Asset Management GmbH17,400$749.1K0.00%00.0%Unchanged
Arizona State Retirement System17,261$743.1K0.01%−291−1.7%Reduced
Eisler Capital (US) LLC16,654$717.0K0.24%+16,654New
Legato Capital Management LLC16,085$692.5K0.08%+4,248+35.9%Added
Gilder Gagnon Howe & Co LLC15,092$649.7K0.01%+15,092New
China Universal Asset Management Co., Ltd.14,520$625.1K0.08%+5,974+69.9%Added
Moody Aldrich Partners LLC14,451$622.1K0.11%+5,328+58.4%Added
Bellevue Group AG14,100$607.0K0.01%−7,900−35.9%Reduced
Handelsbanken Fonder AB14,100$607.0K0.00%00.0%Unchanged
Teacher Retirement System of Texas13,977$602.0K0.00%−11−0.1%Reduced
Advisors Asset Management, Inc.13,717$590.5K0.01%+3,301+31.7%Added
Brinker Capital Investments, LLC13,698$589.7K0.01%+5,481+66.7%Added
Orion Portfolio Solutions, LLC13,698$589.7K0.01%+5,481+66.7%Added
Assetmark, Inc13,185$567.6K0.00%+3,247+32.7%Added
Barclays PLC12,554$540.5K0.00%−99,436−88.8%Reduced
Capstone Investment Advisors, LLC11,402$490.9K0.01%+2,541+28.7%Added
Guggenheim Capital LLC11,388$490.3K0.00%+1,859+19.5%Added
Supplemental Annuity Collective Trust of NJ11,000$473.6K0.15%00.0%Unchanged
Public Employees Retirement Association of Colorado10,633$458.0K0.00%00.0%Unchanged
Great West Life Assurance Co10,032$432.0K0.00%+4,691+87.8%Added
Birchview Capital, LP10,000$430.5K0.35%00.0%Unchanged
Bayesian Capital Management, LP9,700$417.6K0.04%+9,700New
American Century Companies Inc9,655$415.6K0.00%+2,456+34.1%Added
Entropy Technologies, LP9,649$415.4K0.04%+9,649New
Atom Investors LP9,603$413.4K0.05%−5,644−37.0%Reduced
Jane Street Group, LLC8,449$363.7K0.00%−20,941−71.3%Reduced
BNP Paribas Arbitrage, SA8,321$358.2K0.00%+3,931+89.5%Added
UBS Oconnor LLC7,987$343.8K0.01%−6,689−45.6%Reduced
SEI Investments Co7,951$342.3K0.00%−228−2.8%Reduced
Elmwood Wealth Management, Inc.7,943$341.9K0.15%−2,126−21.1%Reduced
Vident Advisory, LLC7,801$335.8K0.01%+2,509+47.4%Added
Man Group plc6,900$297.0K0.00%+6,900New
Virtu Financial LLC6,661$287.0K0.02%+6,661New
Axq Capital, LP5,662$243.7K0.06%−1,344−19.2%Reduced
Snowden Capital Advisors LLC5,499$236.7K0.01%−224−3.9%Reduced
Oppenheimer Asset Management Inc.5,374$231.4K0.00%+946+21.4%Added
ProShare Advisors LLC5,286$227.6K0.00%+565+12.0%Added
Cubist Systematic Strategies, LLC5,105$219.8K0.00%+5,105New
Northwestern Mutual Wealth Management Co5,000$215.3K0.00%00.0%Unchanged
HighMark Wealth Management LLC5,000$215.3K0.13%+5,000New
NEOS Investment Management LLC4,972$214.0K0.01%+4,972New
Corton Capital Inc.4,864$209.4K0.08%+4,864New
Aigen Investment Management, LP4,863$209.4K0.05%−3,180−39.5%Reduced
EntryPoint Capital, LLC4,541$195.5K0.18%+4,541New
Simplex Trading, LLC3,977$171.0K0.00%−24,410−86.0%Reduced
Harbor Capital Advisors, Inc.3,225$139.0K0.02%+3,225New
The PNC Financial Services Group, Inc.2,680$115.4K0.00%+700+35.4%Added
Citigroup Inc2,413$103.9K0.00%−591−19.7%Reduced
IFP Advisors, Inc2,121$91.3K0.00%−27−1.3%Reduced
Virtus ETF Advisers LLC2,103$90.5K0.05%−142−6.3%Reduced
Proequities, Inc.2,000$86.1K0.01%00.0%Unchanged
US Bancorp1,564$67.3K0.00%+631+67.6%Added
Quarry LP1,300$56.0K0.02%+300+30.0%Added
Tower Research Capital LLC (TRC)1,226$52.8K0.00%+212+20.9%Added
Allianz SE1,200$51.7K0.00%+1,200New
Parallel Advisors, LLC1,157$49.8K0.00%+32+2.8%Added
Bank of Montreal909$39.3K0.00%+909New
Advisor Group Holdings, Inc.830$35.7K0.00%−1,835−68.9%Reduced
Accent Capital Management, LLC400$17.2K0.01%00.0%Unchanged
First Horizon Advisors, Inc.370$15.9K0.00%−200−35.1%Reduced
Nelson, Van Denburg & Campbell Wealth Management Group, LLC302$13.0K0.00%+302New
State of Wyoming300$12.9K0.00%+300New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.276$11.9K0.00%+276New
Daiwa Securities Group Inc.252$11.0K0.00%00.0%Unchanged