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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2023

Institutional positions in Xenon Pharmaceuticals Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
181
+8 vs. Q2 2023
Shares held
61.3M
+2.13M (+3.6%) vs. Q2 2023
Total value
$2.10B
−$183.4M (−8.0%) vs. Q2 2023
New holders
23
71 more added
Sold out
15
50 more reduced

2 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 181 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ3 2023: $2.10B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q2 2023.

Institutions holding XENE in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Steward Financial Group LLC12$00.00%+12New
AdvisorNet Financial, Inc3$1020.00%+2+200.0%Added
SJS Investment Consulting Inc.3$1030.00%+1+50.0%Added
Signaturefd, LLC4$1370.00%−9−69.2%Reduced
JFS Wealth Advisors, LLC7$2400.00%+6+600.0%Added
Hexagon Capital Partners LLC10$3420.00%−72−87.8%Reduced
Lindbrook Capital, LLC14$4780.00%+14New
Larson Financial Group LLC17$5810.00%+17New
Park Place Capital Corp22$7520.00%00.0%Unchanged
Headlands Technologies LLC27$9220.00%+27New
Whittier Trust Co of Nevada Inc38$1.30K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)197$6.73K0.00%−5,327−96.4%Reduced
US Bancorp259$8.85K0.00%00.0%Unchanged
Daiwa Securities Group Inc.252$9.00K0.00%00.0%Unchanged
Householder Group Estate & Retirement Specialist, LLC283$9.67K0.00%+283New
First Horizon Advisors, Inc.570$19.5K0.00%00.0%Unchanged
Parallel Advisors, LLC744$25.4K0.00%−32−4.1%Reduced
Belvedere Trading LLC955$32.6K0.00%+955New
China Universal Asset Management Co., Ltd.1,651$56.4K0.02%+818+98.2%Added
BNP Paribas Arbitrage, SA1,683$57.5K0.00%+242+16.8%Added
Proequities, Inc.2,000$68.3K0.01%00.0%Unchanged
IFP Advisors, Inc2,178$74.4K0.00%00.0%Unchanged
Virtus ETF Advisers LLC2,324$79.4K0.05%−228−8.9%Reduced
Deutsche Bank AG2,495$85.2K0.00%−539−17.8%Reduced
Citigroup Inc2,866$97.9K0.00%−1,288−31.0%Reduced
Advisor Group Holdings, Inc.3,887$132.8K0.00%+1,196+44.4%Added
Exchange Traded Concepts, LLC3,967$135.5K0.00%+720+22.2%Added
Great West Life Assurance Co4,493$153.0K0.00%+2,800+165.4%Added
Quarry LP4,500$153.7K0.10%+4,500New
Northwestern Mutual Wealth Management Co5,000$170.8K0.00%00.0%Unchanged
Snowden Capital Advisors LLC5,865$200.3K0.01%−131−2.2%Reduced
UBS Group AG5,882$200.9K0.00%+1,003+20.6%Added
Oppenheimer Asset Management Inc.6,211$212.2K0.00%−19−0.3%Reduced
Walleye Trading LLC6,923$236.5K0.01%+1,254+22.1%Added
Assetmark, Inc7,103$242.6K0.00%+1,258+21.5%Added
Group One Trading, L.P.8,005$273.5K0.01%+8,005New
Connacht Asset Management LP8,204$280.2K1.66%+2,039+33.1%Added
SEI Investments Co8,337$284.8K0.00%−6,090−42.2%Reduced
Moody Aldrich Partners LLC9,123$311.6K0.06%+9,123New
Dynamic Technology Lab Private Ltd9,371$320.0K0.03%+9,371New
Caption Management, LLC9,500$324.5K0.04%+9,500New
Barclays PLC9,521$325.2K0.00%+342+3.7%Added
Birchview Capital, LP10,000$341.6K0.29%00.0%Unchanged
Natixis10,000$341.6K0.00%+3,000+42.9%Added
Elmwood Wealth Management, Inc.10,069$344.0K0.17%00.0%Unchanged
Advisors Asset Management, Inc.10,188$348.0K0.01%+2,096+25.9%Added
Public Employees Retirement Association of Colorado10,633$363.0K0.00%00.0%Unchanged
Simplex Trading, LLC10,735$366.0K0.01%+10,735New
Supplemental Annuity Collective Trust of NJ11,000$375.8K0.14%00.0%Unchanged
Jefferies Financial Group Inc.11,088$378.8K0.01%+2,319+26.4%Added
Guggenheim Capital LLC11,132$380.3K0.00%+758+7.3%Added
Zurcher Kantonalbank (Zurich Cantonalbank)11,623$397.0K0.00%+2,430+26.4%Added
Legato Capital Management LLC11,682$399.1K0.06%−628−5.1%Reduced
Allianz Asset Management GmbH13,200$450.9K0.00%00.0%Unchanged
Handelsbanken Fonder AB14,100$482.0K0.00%00.0%Unchanged
Teacher Retirement System of Texas14,418$493.0K0.00%+746+5.5%Added
Arizona State Retirement System14,478$494.6K0.00%+313+2.2%Added
Aquatic Capital Management LLC15,300$523.0K0.02%+15,300New
Brinker Capital Investments, LLC15,402$526.1K0.01%−404−2.6%Reduced
Orion Portfolio Solutions, LLC15,402$526.1K0.01%−404−2.6%Reduced
Prelude Capital Management, LLC15,758$538.3K0.05%+286+1.8%Added
J. Goldman & Co LP17,775$607.2K0.03%−30,266−63.0%Reduced
Man Group plc–$632.0K0.00%–New
Stifel Financial Corp20,480$699.6K0.00%+399+2.0%Added
DekaBank Deutsche Girozentrale20,000$707.0K0.00%00.0%Unchanged
Sanders Morris Harris LLC21,500$718.1K0.15%00.0%Unchanged
Renaissance Technologies LLC21,900$748.0K0.00%+21,900New
Natixis Advisors, L.P.22,024$752.0K0.00%+40.0%Added
Chartwell Investment Partners, LLC23,301$796.0K0.03%00.0%Unchanged
Rathbone Brothers plc23,666$808.4K0.01%+23,666New
Knott David M Jr23,866$815.0K0.32%00.0%Unchanged
Bellevue Group AG23,900$816.4K0.01%00.0%Unchanged
Jane Street Group, LLC24,479$836.2K0.00%+15,762+180.8%Added
NJ State Employees Deferred Compensation Plan25,000$854.0K0.13%00.0%Unchanged
LMR Partners LLP25,000$854.0K0.02%+25,000New
Royal Bank of Canada27,121$927.0K0.00%+2,920+12.1%Added
Prudential Financial Inc27,000$953.9K0.00%+27,000New
TLS Advisors LLC32,956$1.13M4.56%−800−2.4%Reduced
HRT Financial LP35,210$1.20M0.01%+17,264+96.2%Added
HighVista Strategies LLC35,255$1.20M0.56%+17,680+100.6%Added
Erste Asset Management GmbH35,000$1.24M0.02%00.0%Unchanged
Advisory Research Inc38,326$1.31M0.18%−6,096−13.7%Reduced
Sphera Funds Management Ltd.38,959$1.33M0.32%+38,959New
D. E. Shaw & Co., Inc.40,547$1.39M0.00%−58,198−58.9%Reduced
Nuveen Asset Management, LLC41,695$1.42M0.00%+1,496+3.7%Added
Envestnet Asset Management Inc44,102$1.51M0.00%+27,580+166.9%Added
Legal & General Group Plc44,713$1.53M0.00%+1,921+4.5%Added
California State Teachers Retirement System44,950$1.54M0.00%+575+1.3%Added
CIBC World Markets Inc.45,372$1.55M0.01%+4,150+10.1%Added
Alps Advisors Inc47,349$1.62M0.01%+626+1.3%Added
UBS Oconnor LLC48,676$1.66M0.03%+10,000+25.9%Added
JPMorgan Chase & Co50,297$1.72M0.00%−28,920−36.5%Reduced
Soleus Capital Management, L.P.52,000$1.78M0.18%−14,000−21.2%Reduced
Silverarc Capital Management, LLC53,996$1.84M0.69%−45,760−45.9%Reduced
Qube Research & Technologies Ltd54,285$1.85M0.01%+24,318+81.1%Added
Geode Capital Management, LLC55,945$1.91M0.00%+30+0.1%Added
SG Americas Securities, LLC56,752$1.94M0.03%+17,490+44.5%Added
Wells Fargo & Company59,633$2.04M0.00%+1,040+1.8%Added
State of New Jersey Common Pension Fund D64,454$2.20M0.01%00.0%Unchanged
Two Sigma Advisers, LP64,900$2.22M0.01%+64,900New