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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2023

Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
175
+13 vs. Q1 2023
Shares held
61.3M
+174.4K (+0.3%) vs. Q1 2023
Total value
$2.36B
+$174.7M (+8.0%) vs. Q1 2023
New holders
33
57 more added
Sold out
20
56 more reduced

1 institution that held it in Q1 2023 haven't filed for Q2 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 175 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ2 2023: $2.36B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2023.

Institutions holding XENE in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Walleye Capital LLC89,704$3.45M0.06%−15,628−14.8%Reduced
Castleark Management LLC94,490$3.64M0.16%+16,750+21.5%Added
D. E. Shaw & Co., Inc.98,745$3.80M0.01%−107,927−52.2%Reduced
Silverarc Capital Management, LLC99,756$3.84M1.30%+3,113+3.2%Added
Bamco Inc100,100$3.85M0.01%+27,100+37.1%Added
PFM Health Sciences, LP100,147$3.86M0.16%00.0%Unchanged
Swiss National Bank109,800$4.23M0.00%+8,500+8.4%Added
DnB Asset Management AS112,629$4.34M0.02%+13,770+13.9%Added
Nan Fung Group Holdings Ltd114,380$4.40M2.81%00.0%Unchanged
Ikarian Capital, LLC135,486$5.22M1.84%−25,000−15.6%Reduced
Algert Global LLC144,877$5.58M0.24%+106,470+277.2%Added
Point72 Asset Management, L.P.148,208$5.71M0.02%−356,416−70.6%Reduced
Russell Investments Group, Ltd.150,456$5.79M0.01%+65,098+76.3%Added
Bank of America Corp159,376$6.14M0.00%+25,265+18.8%Added
Ensign Peak Advisors, Inc164,380$6.33M0.01%00.0%Unchanged
Putnam Investments LLC165,262$6.36M0.01%+11,807+7.7%Added
Eversept Partners, LP171,378$6.60M0.70%−31,894−15.7%Reduced
Franklin Resources Inc172,612$6.65M0.00%+30.0%Added
Schonfeld Strategic Advisors LLC180,143$6.94M0.06%−119,976−40.0%Reduced
New York State Common Retirement Fund184,631$7.11M0.01%+164,952+838.2%Added
Ghost Tree Capital, LLC185,000$7.12M2.57%−15,000−7.5%Reduced
Jennison Associates LLC188,391$7.25M0.01%+188,391New
AXA S.A.193,035$7.43M0.02%+2,655+1.4%Added
Bank of Montreal191,011$7.83M0.00%+191,011New
Morgan Stanley205,536$7.91M0.00%−37,445−15.4%Reduced
Bank of New York Mellon Corp211,741$8.15M0.00%+12,354+6.2%Added
State of Wisconsin Investment Board212,129$8.17M0.02%−1,927−0.9%Reduced
State Street Corp212,550$8.18M0.00%+5,094+2.5%Added
Millennium Management LLC213,338$8.21M0.01%−8,132−3.7%Reduced
Parkman Healthcare Partners LLC217,740$8.38M1.45%−59,543−21.5%Reduced
Altium Capital Management LP228,000$8.78M6.86%+228,000New
Granahan Investment Management Inc236,753$9.11M0.28%−39,259−14.2%Reduced
Vanguard Group Inc261,353$10.1M0.00%+11,999+4.8%Added
Dimensional Fund Advisors LP262,107$10.1M0.00%+196,841+301.6%Added
Ally Bridge Group (NY) LLC266,961$10.3M12.45%00.0%Unchanged
Logos Global Management LP275,000$10.6M1.46%−625,000−69.4%Reduced
Goldman Sachs Group Inc275,080$10.6M0.00%−10,343−3.6%Reduced
DAFNA Capital Management LLC280,538$10.8M2.95%−35,554−11.2%Reduced
Woodline Partners LP290,400$11.2M0.13%−129,629−30.9%Reduced
Janus Henderson Group PLC327,344$12.6M0.01%+5,879+1.8%Added
First Light Asset Management, LLC338,646$13.0M1.02%+59,202+21.2%Added
Eventide Asset Management, LLC413,906$15.9M0.27%−227,294−35.4%Reduced
TimesSquare Capital Management, LLC426,925$16.4M0.24%+19,130+4.7%Added
Avidity Partners Management LP481,300$18.5M0.65%+481,300New
Citadel Advisors LLC501,012$19.3M0.02%−370,222−42.5%Reduced
Great Point Partners LLC530,000$20.4M4.09%−288,505−35.2%Reduced
Fiera Capital Corp549,341$21.1M0.06%+549,341New
Boxer Capital, LLC600,000$23.1M1.07%00.0%Unchanged
Adage Capital Partners GP, L.L.C.670,000$25.8M0.06%−80,000−10.7%Reduced
Invesco Ltd.699,985$26.9M0.01%+683,514+4,149.8%Added
Candriam Luxembourg S.C.A.705,884$27.2M0.20%−13,322−1.9%Reduced
Holocene Advisors, LP712,478$27.4M0.12%−273,717−27.8%Reduced
Baker Bros. Advisors LP751,639$28.9M0.17%00.0%Unchanged
Loomis Sayles & Co L P753,526$29.0M0.05%−7,041−0.9%Reduced
Nicholas Investment Partners, LP791,118$30.5M2.08%+354,403+81.2%Added
Samlyn Capital, LLC939,909$36.2M0.63%−219,085−18.9%Reduced
Paradigm Biocapital Advisors LP989,327$38.1M3.08%+338,259+52.0%Added
BlackRock Inc.994,040$38.3M0.00%+94,886+10.6%Added
Wellington Management Group LLP1,051,051$40.5M0.01%+803,614+324.8%Added
OrbiMed Advisors LLC1,096,000$42.2M0.82%−53,100−4.6%Reduced
Redmile Group, LLC1,120,476$43.1M1.66%−205,356−15.5%Reduced
Rock Springs Capital Management LP1,178,002$45.4M1.08%00.0%Unchanged
Perceptive Advisors LLC1,223,377$47.1M1.37%−608,797−33.2%Reduced
BVF Inc1,827,958$70.4M1.96%00.0%Unchanged
Braidwell LP1,828,353$70.4M2.30%−308,757−14.4%Reduced
Commodore Capital LP1,845,000$71.0M7.98%00.0%Unchanged
Lord, Abbett & Co. LLC1,958,540$75.4M0.26%+175,929+9.9%Added
Pictet Asset Management SA2,032,730$78.3M0.09%+28,433+1.4%Added
Capital World Investors2,274,974$87.6M0.02%00.0%Unchanged
Marshall Wace, LLP2,320,419$89.3M0.19%−1670.0%Reduced
Capital International Investors2,321,991$89.4M0.02%00.0%Unchanged
Polar Capital Holdings Plc3,022,071$116.3M0.80%+5,253+0.2%Added
Driehaus Capital Management LLC4,760,853$183.3M2.31%+105,928+2.3%Added
Avoro Capital Advisors LLC4,900,000$188.7M2.56%00.0%Unchanged
FMR LLC5,188,707$199.8M0.02%+460,858+9.7%Added
Norges Bank0$00.00%−365,830−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−302,980−100.0%Sold out
Nomura Holdings Inc0$00.00%−221,095−100.0%Sold out
Weiss Multi-Strategy Advisers LLC0$00.00%−54,140−100.0%Sold out
Moore Capital Management, LP0$00.00%−34,417−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−29,908−100.0%Sold out
Kynam Capital Management, LP0$00.00%−28,696−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−18,562−100.0%Sold out
Oppenheimer & Co Inc0$00.00%−12,615−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−10,900−100.0%Sold out
Virginia Retirement Systems Et Al0$00.00%−10,300−100.0%Sold out
American Century Companies Inc0$00.00%−9,474−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−8,400−100.0%Sold out
Kapitalo Investimentos Ltda0$00.00%−3,612−100.0%Sold out
Values First Advisors, Inc.0$00.00%−3,498−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−2,455−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−2,000−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−1,955−100.0%Sold out
Belpointe Asset Management LLC0$00.00%−70−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−11,802−100.0%Sold out
Householder Group Estate & Retirement Specialist, LLC––––Not filed