Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2022
Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 151
- +21 vs. Q1 2022
- Shares held
- 57.0M
- +7.91M (+16.1%) vs. Q1 2022
- Total value
- $1.73B
- +$235.7M (+15.7%) vs. Q1 2022
- New holders
- 38
- 55 more added
- Sold out
- 17
- 40 more reduced
2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| EAM Global Investors LLC | 150,489 | $4.58M | 1.12% | +150,489 | New |
| Walleye Capital LLC | 161,927 | $4.93M | 0.14% | +7,619+4.9% | Added |
| Tri Locum Partners LP | 166,399 | $5.06M | 2.08% | +166,399 | New |
| Moore Capital Management, LP | 172,071 | $5.23M | 0.16% | +143,392+500.0% | Added |
| Dimensional Fund Advisors LP | 174,962 | $5.32M | 0.00% | −118,767−40.4% | Reduced |
| Kynam Capital Management, LP | 175,000 | $5.32M | 1.37% | −308,270−63.8% | Reduced |
| Vanguard Group Inc | 183,845 | $5.59M | 0.00% | +20,377+12.5% | Added |
| AXA S.A. | 191,351 | $5.82M | 0.02% | −3,701−1.9% | Reduced |
| State Street Corp | 197,221 | $6.00M | 0.00% | +25,234+14.7% | Added |
| Woodline Partners LP | 228,928 | $6.96M | 0.11% | +228,928 | New |
| Silverarc Capital Management, LLC | 232,630 | $7.08M | 3.32% | +131,549+130.1% | Added |
| Ikarian Capital, LLC | 239,441 | $7.28M | 3.02% | 00.0% | Unchanged |
| Acuta Capital Partners, LLC | 272,500 | $8.29M | 4.64% | +47,500+21.1% | Added |
| Janus Henderson Group PLC | 276,674 | $8.41M | 0.01% | +266,393+2,591.1% | Added |
| Granahan Investment Management Inc | 284,772 | $8.66M | 0.30% | +22,067+8.4% | Added |
| Parkman Healthcare Partners LLC | 294,559 | $8.96M | 3.30% | −9,627−3.2% | Reduced |
| Goldman Sachs Group Inc | 296,314 | $9.01M | 0.00% | −428,023−59.1% | Reduced |
| D. E. Shaw & Co., Inc. | 326,542 | $9.93M | 0.02% | −3,985−1.2% | Reduced |
| Alliancebernstein L.P. | 429,960 | $13.1M | 0.01% | +53,309+14.2% | Added |
| DAFNA Capital Management LLC | 438,623 | $13.3M | 3.64% | +58,460+15.4% | Added |
| Avidity Partners Management LP | 450,000 | $13.7M | 0.31% | +450,000 | New |
| Eversept Partners, LP | 465,911 | $14.2M | 1.38% | +55,890+13.6% | Added |
| Eventide Asset Management, LLC | 469,700 | $14.3M | 0.31% | +469,700 | New |
| Millennium Management LLC | 492,691 | $15.0M | 0.02% | +356,365+261.4% | Added |
| Bank of New York Mellon Corp | 563,187 | $17.1M | 0.00% | −16,021−2.8% | Reduced |
| Boxer Capital, LLC | 600,000 | $18.3M | 1.16% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 630,000 | $19.2M | 0.04% | −20,000−3.1% | Reduced |
| Baker Bros. Advisors LP | 751,639 | $22.9M | 0.13% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 863,140 | $26.3M | 0.22% | +258,886+42.8% | Added |
| BlackRock Inc. | 868,290 | $26.4M | 0.00% | +253,333+41.2% | Added |
| Point72 Asset Management, L.P. | 901,506 | $27.4M | 0.13% | −1,244,944−58.0% | Reduced |
| Morgan Stanley | 998,072 | $30.4M | 0.00% | −442,099−30.7% | Reduced |
| Great Point Partners LLC | 1,104,334 | $33.6M | 8.66% | +184,334+20.0% | Added |
| Samlyn Capital, LLC | 1,116,436 | $34.0M | 0.68% | +485,707+77.0% | Added |
| Rock Springs Capital Management LP | 1,123,604 | $34.2M | 0.99% | +281,106+33.4% | Added |
| OrbiMed Advisors LLC | 1,329,200 | $40.4M | 0.79% | +643,200+93.8% | Added |
| Capital International Investors | 1,582,508 | $48.1M | 0.01% | +714,211+82.3% | Added |
| Commodore Capital LP | 1,594,932 | $48.5M | 10.26% | +392,319+32.6% | Added |
| BVF Inc | 1,597,966 | $48.6M | 2.35% | 00.0% | Unchanged |
| Redmile Group, LLC | 1,639,344 | $49.9M | 1.90% | +1,639,344 | New |
| Citadel Advisors LLC | 1,648,039 | $50.1M | 0.07% | +206,959+14.4% | Added |
| Pictet Asset Management SA | 1,819,476 | $55.3M | 0.08% | +494,150+37.3% | Added |
| Holocene Advisors, LP | 1,829,152 | $55.6M | 0.34% | +919,524+101.1% | Added |
| Lord, Abbett & Co. LLC | 1,857,596 | $56.5M | 0.20% | +66,853+3.7% | Added |
| Marshall Wace, LLP | 1,990,372 | $60.5M | 0.14% | +456,314+29.7% | Added |
| Perceptive Advisors LLC | 2,122,535 | $64.6M | 2.03% | −288,912−12.0% | Reduced |
| Capital World Investors | 2,274,974 | $69.2M | 0.01% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 2,540,059 | $77.3M | 0.60% | +350,000+16.0% | Added |
| Driehaus Capital Management LLC | 4,391,038 | $133.6M | 2.16% | +1,090,611+33.0% | Added |
| FMR LLC | 4,572,368 | $139.1M | 0.01% | +738,892+19.3% | Added |
| Avoro Capital Advisors LLC | 4,900,000 | $149.1M | 2.95% | −85,000−1.7% | Reduced |
| Suvretta Capital Management, LLC | 0 | $0 | 0.00% | −692,000−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −232,650−100.0% | Sold out |
| Invesco Ltd. | 0 | $0 | 0.00% | −198,701−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −150,777−100.0% | Sold out |
| Ci Investments Inc. | 0 | $0 | 0.00% | −100,705−100.0% | Sold out |
| Ghost Tree Capital, LLC | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Affinity Asset Advisors, LLC | 0 | $0 | 0.00% | −80,000−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −30,101−100.0% | Sold out |
| Royal Bank of Canada | 0 | $0 | 0.00% | −24,313−100.0% | Sold out |
| Granite Point Capital Management, L.P. | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −16,117−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −13,993−100.0% | Sold out |
| Teacher Retirement System of Texas | 0 | $0 | 0.00% | −8,545−100.0% | Sold out |
| Connor, Clark & Lunn Investment Management Ltd. | 0 | $0 | 0.00% | −7,658−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| Brown Brothers Harriman & Co | 0 | $0 | 0.00% | −294−100.0% | Sold out |
| Barclays PLC | 0 | $0 | 0.00% | −191−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | – | – | – | – | Not filed |
| Parametric Portfolio Associates LLC | – | – | – | – | Not filed |