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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2024

Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
240
+55 vs. Q2 2024
Shares held
61.8M
+8.87M (+16.8%) vs. Q2 2024
Total value
$2.78B
+$946.0M (+51.6%) vs. Q2 2024
New holders
79
77 more added
Sold out
24
64 more reduced

3 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 240 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ3 2024: $2.78B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2024.

Institutions holding PTGX in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Mariner, LLC15,979$719.0K0.00%+3,696+30.1%Added
State Board of Administration of Florida Retirement System16,303$733.6K0.00%00.0%Unchanged
Amalgamated Bank17,324$780.0K0.01%+15,301+756.4%Added
Squarepoint Ops LLC18,566$835.5K0.00%+8,743+89.0%Added
Intech Investment Management LLC19,128$860.8K0.01%+19,128New
Janney Montgomery Scott LLC19,249$866.0K0.00%+19,249New
Allianz Asset Management GmbH19,300$868.5K0.00%+8,200+73.9%Added
Maryland State Retirement & Pension System19,892$895.1K0.02%+19,892New
Profund Advisors LLC20,083$903.7K0.03%+5,554+38.2%Added
New York State Common Retirement Fund20,182$908.2K0.00%−2,900−12.6%Reduced
Teachers Retirement System of the State of Kentucky20,200$909.0K0.01%+20,200New
BNP Paribas Arbitrage, SA20,294$913.2K0.00%+16,597+448.9%Added
Comerica Bank20,904$940.7K0.00%+20,634+7,642.2%Added
Sierra Summit Advisors LLC21,167$952.5K0.22%+21,167New
Janus Henderson Group PLC21,454$965.0K0.00%00.0%Unchanged
STRS Ohio21,500$967.5K0.00%−3,400−13.7%Reduced
Toroso Investments, LLC22,062$992.8K0.01%00.0%Unchanged
Caption Management, LLC22,100$994.5K0.11%+22,100New
Los Angeles Capital Management LLC22,446$1.01M0.00%−8,381−27.2%Reduced
Trexquant Investment LP23,091$1.04M0.01%−57,523−71.4%Reduced
Yousif Capital Management, LLC23,240$1.05M0.01%+23,240New
Financial Enhancement Group LLC41,818$1.06M0.21%+41,818New
Quest Partners LLC23,947$1.08M0.10%+21,516+885.1%Added
New York State Teachers Retirement System24,592$1.11M0.00%+24,592New
AlphaCentric Advisors LLC25,000$1.13M0.84%00.0%Unchanged
Gsa Capital Partners LLP25,095$1.13M0.09%+66+0.3%Added
SG Americas Securities, LLC25,740$1.16M0.00%+14,789+135.0%Added
Winton Group Ltd25,983$1.17M0.08%+25,983New
D. E. Shaw & Co., Inc.26,825$1.21M0.00%+13,673+104.0%Added
Ensign Peak Advisors, Inc27,036$1.22M0.00%00.0%Unchanged
State of Tennessee, Treasury Department27,743$1.25M0.00%+27,743New
Louisiana State Employees Retirement System28,500$1.28M0.02%+28,500New
Illinois Municipal Retirement Fund29,124$1.31M0.02%+29,124New
Wells Fargo & Company29,373$1.32M0.00%−817−2.7%Reduced
Cavalier Investments, LLC29,956$1.35M0.41%+29,956New
Wellington Management Group LLP30,079$1.35M0.00%+30,079New
Jane Street Group, LLC32,858$1.48M0.00%−136,453−80.6%Reduced
Quantedge Capital Pte Ltd32,983$1.48M0.44%+32,983New
Corebridge Financial, Inc.33,562$1.51M0.01%+2,122+6.7%Added
State of Alaska, Department of Revenue33,615$1.51M0.02%+33,615New
MetLife Investment Management33,805$1.52M0.01%00.0%Unchanged
SEI Investments Co35,078$1.58M0.00%−6,685−16.0%Reduced
Mirae Asset Global ETFs Holdings Ltd.35,505$1.60M0.00%+3,385+10.5%Added
CWM Advisors, LLC36,514$1.64M0.17%+26,280+256.8%Added
Hennion & Walsh Asset Management, Inc.37,413$1.68M0.08%−467−1.2%Reduced
Susquehanna International Group, LLP40,357$1.82M0.00%−315,229−88.7%Reduced
California State Teachers Retirement System42,665$1.92M0.00%−1,130−2.6%Reduced
Jackson Creek Investment Advisors LLC44,685$2.01M0.60%+10,034+29.0%Added
Point72 Europe (London) LLP45,317$2.04M0.17%+45,317New
Thrivent Financial for Lutherans46,257$2.08M0.00%+46,257New
State of Wisconsin Investment Board47,160$2.12M0.01%−8,791−15.7%Reduced
Birchview Capital, LP48,000$2.16M1.87%00.0%Unchanged
Swedbank AB50,000$2.25M0.00%+50,000New
Alps Advisors Inc52,032$2.34M0.02%+6,260+13.7%Added
Knott David M Jr52,368$2.36M0.94%00.0%Unchanged
Man Group plc55,831$2.51M0.01%+48,176+629.3%Added
Great West Life Assurance Co56,536$2.54M0.00%+51,323+984.5%Added
Prudential Financial Inc60,798$2.74M0.00%+60,798New
Schonfeld Strategic Advisors LLC61,026$2.75M0.02%+11,962+24.4%Added
Weiss Asset Management LP62,463$2.81M0.07%+62,463New
Great Lakes Advisors, LLC69,625$3.13M0.03%−23,854−25.5%Reduced
E Fund Management Co., Ltd.71,666$3.22M0.17%+71,666New
Citigroup Inc73,490$3.31M0.00%+52,475+249.7%Added
UBS Group AG78,799$3.55M0.00%+11,818+17.6%Added
Northwestern Mutual Wealth Management Co78,894$3.55M0.00%−78,894−50.0%Reduced
Alliancebernstein L.P.81,919$3.69M0.00%−13,250−13.9%Reduced
Franklin Resources Inc81,591$3.78M0.00%+45,674+127.2%Added
Silvercrest Asset Management Group LLC85,254$3.84M0.03%−105,914−55.4%Reduced
Swiss National Bank85,900$3.87M0.00%00.0%Unchanged
HighVista Strategies LLC89,508$4.03M1.39%+68,279+321.6%Added
Rafferty Asset Management, LLC89,876$4.04M0.01%+14,606+19.4%Added
Allspring Global Investments Holdings, LLC103,842$4.67M0.01%+103,414+24,162.1%Added
Opaleye Management Inc.105,000$4.72M0.79%00.0%Unchanged
Walleye Capital LLC105,335$4.74M0.05%+105,335New
Voya Investment Management LLC113,852$5.12M0.01%+48,786+75.0%Added
Algert Global LLC115,679$5.21M0.14%−36,400−23.9%Reduced
Manufacturers Life Insurance Company, The115,765$5.21M0.00%+1,359+1.2%Added
Moody Aldrich Partners LLC119,287$5.37M0.98%−14,928−11.1%Reduced
Deutsche Bank AG120,169$5.41M0.00%−788,179−86.8%Reduced
Segall Bryant & Hamill, LLC120,301$5.41M0.07%+1,739+1.5%Added
Artia Global Partners LP124,440$5.60M1.58%00.0%Unchanged
Public Sector Pension Investment Board124,949$5.62M0.03%+124,949New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.125,898$5.67M0.01%+125,898New
Barclays PLC126,995$5.71M0.00%+87,755+223.6%Added
Jacobs Levy Equity Management, Inc128,654$5.79M0.02%−357−0.3%Reduced
Victory Capital Management Inc130,797$5.89M0.01%+123,647+1,729.3%Added
AQR Capital Management LLC137,171$6.17M0.01%+112,116+447.5%Added
First Trust Advisors LP140,924$6.34M0.01%+9,114+6.9%Added
Ameriprise Financial Inc143,807$6.47M0.00%+143,807New
Renaissance Technologies LLC144,167$6.49M0.01%−153,300−51.5%Reduced
Silverarc Capital Management, LLC146,657$6.60M1.49%+146,657New
Legal & General Group Plc153,006$6.89M0.00%+99,720+187.1%Added
Bank of America Corp153,517$6.91M0.00%−146,964−48.9%Reduced
Arrowstreet Capital, Limited Partnership158,067$7.11M0.01%+158,067New
Candriam Luxembourg S.C.A.162,492$7.31M0.04%−111,326−40.7%Reduced
Rhumbline Advisers164,178$7.39M0.01%+79,203+93.2%Added
TD Asset Management Inc172,202$7.67M0.01%+23,900+16.1%Added
Point72 Asset Management, L.P.214,872$9.67M0.03%−694,862−76.4%Reduced
Dimensional Fund Advisors LP225,589$10.2M0.00%−390,583−63.4%Reduced
Skandinaviska Enskilda Banken AB (publ)230,114$10.4M0.05%+211,200+1,116.6%Added