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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2023

Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
167
+29 vs. Q1 2023
Shares held
56.7M
+3.51M (+6.6%) vs. Q1 2023
Total value
$1.57B
+$342.2M (+27.9%) vs. Q1 2023
New holders
43
60 more added
Sold out
14
48 more reduced

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 167 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ2 2023: $1.57B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2023.

Institutions holding PTGX in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
D. E. Shaw & Co., Inc.72,686$2.01M0.00%−126,830−63.6%Reduced
Thrivent Financial for Lutherans73,381$2.03M0.00%−27,612−27.3%Reduced
Integral Health Asset Management, LLC75,000$2.07M0.27%+75,000New
Rhumbline Advisers77,911$2.15M0.00%+3,202+4.3%Added
Alliancebernstein L.P.80,200$2.22M0.00%+26,000+48.0%Added
Suvretta Capital Management, LLC81,143$2.24M0.12%+81,143New
EAM Investors, LLC87,953$2.43M0.45%+87,953New
Swiss National Bank98,000$2.71M0.00%+18,300+23.0%Added
Ameriprise Financial Inc99,930$2.76M0.00%+81,572+444.3%Added
Citigroup Inc107,521$2.97M0.00%−84,828−44.1%Reduced
Artia Global Partners LP112,340$3.10M1.07%+112,340New
Eversept Partners, LP114,659$3.17M0.33%+114,659New
Silvercrest Asset Management Group LLC128,197$3.54M0.03%+14,842+13.1%Added
Public Sector Pension Investment Board146,000$4.03M0.03%00.0%Unchanged
Jacobs Levy Equity Management, Inc146,487$4.05M0.02%−74,504−33.7%Reduced
Great Lakes Advisors, LLC147,048$4.06M0.04%−3,436−2.3%Reduced
Connor, Clark & Lunn Investment Management Ltd.163,425$4.51M0.02%+41,401+33.9%Added
Marshall Wace, LLP164,500$4.54M0.01%−1,201,580−88.0%Reduced
Allspring Global Investments Holdings, LLC175,529$4.85M0.01%−48,135−21.5%Reduced
Barclays PLC193,439$5.34M0.00%−390,298−66.9%Reduced
SG Americas Securities, LLC195,756$5.41M0.05%+177,241+957.3%Added
Bank of New York Mellon Corp199,575$5.51M0.00%+31,042+18.4%Added
BNP Paribas Arbitrage, SA202,310$5.59M0.01%−35,314−14.9%Reduced
Readystate Asset Management LP204,880$5.66M0.56%+204,880New
Gratus Capital LLC219,586$6.06M0.42%+7,855+3.7%Added
Ghost Tree Capital, LLC225,000$6.21M2.24%00.0%Unchanged
Invesco Ltd.264,411$7.30M0.00%−13,525−4.9%Reduced
JPMorgan Chase & Co264,707$7.31M0.00%+158,574+149.4%Added
Rafferty Asset Management, LLC285,459$7.88M0.04%+132,072+86.1%Added
Bank of America Corp296,240$8.18M0.00%−470,750−61.4%Reduced
Bank of Montreal310,000$8.68M0.01%+310,000New
Eventide Asset Management, LLC320,000$8.84M0.15%+320,000New
Millennium Management LLC351,810$9.72M0.01%−770,532−68.7%Reduced
Two Sigma Investments, LP376,473$10.4M0.03%+68,773+22.4%Added
Renaissance Technologies LLC390,267$10.8M0.02%−300,600−43.5%Reduced
Kennedy Capital Management, Inc.403,648$11.1M0.26%+72,366+21.8%Added
Two Sigma Advisers, LP412,100$11.4M0.03%−37,700−8.4%Reduced
Charles Schwab Investment Management Inc419,610$11.6M0.00%+58,452+16.2%Added
Woodline Partners LP427,264$11.8M0.14%−191,351−30.9%Reduced
Artal Group S.A.500,000$13.8M0.44%+500,000New
FMR LLC507,407$14.0M0.00%+459,087+950.1%Added
Northern Trust Corp538,125$14.9M0.00%+115,489+27.3%Added
Citadel Advisors LLC548,994$15.2M0.02%−615,686−52.9%Reduced
Goldman Sachs Group Inc559,210$15.4M0.00%+99,760+21.7%Added
HSBC Holdings PLC560,455$15.7M0.02%+560,455New
Morgan Stanley578,021$16.0M0.00%−992,489−63.2%Reduced
Candriam Luxembourg S.C.A.725,000$20.0M0.14%+100,000+16.0%Added
Jefferies Financial Group Inc.760,561$21.0M0.45%+760,561New
Holocene Advisors, LP802,531$22.2M0.10%+802,531New
683 Capital Management, LLC814,000$22.5M2.19%+23,000+2.9%Added
Price T Rowe Associates Inc831,693$23.0M0.00%+416,419+100.3%Added
Deutsche Bank AG861,324$23.8M0.01%−97,567−10.2%Reduced
Nuveen Asset Management, LLC935,961$25.9M0.01%+107,490+13.0%Added
Kynam Capital Management, LP975,298$26.9M4.13%−399,702−29.1%Reduced
Dimensional Fund Advisors LP1,039,105$28.7M0.01%−223,154−17.7%Reduced
Geode Capital Management, LLC1,077,184$29.8M0.00%+151,191+16.3%Added
Adage Capital Partners GP, L.L.C.1,292,711$35.7M0.08%−1,265,289−49.5%Reduced
Perceptive Advisors LLC1,469,761$40.6M1.18%+504,609+52.3%Added
Cormorant Asset Management, LP1,500,000$41.4M2.36%−200,000−11.8%Reduced
Cowen and Company, LLC1,657,551$45.8M3.79%+1,657,551New
Johnson & Johnson2,449,183$67.6M21.00%00.0%Unchanged
Vanguard Group Inc3,147,755$86.9M0.00%−93,538−2.9%Reduced
State Street Corp3,551,986$98.1M0.01%+1,138,285+47.2%Added
BVF Inc3,775,900$104.3M2.91%00.0%Unchanged
Farallon Capital Management, L.L.C.4,511,430$124.6M0.74%+1,896,416+72.5%Added
BlackRock Inc.5,009,273$138.4M0.00%+607,056+13.8%Added
RTW Investments, LP5,415,514$149.6M2.85%+814,715+17.7%Added
Jennison Associates LLC0$00.00%−428,938−100.0%Sold out
OrbiMed Advisors LLC0$00.00%−301,000−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−148,992−100.0%Sold out
Walleye Trading LLC0$00.00%−105,360−100.0%Sold out
Prudential Financial Inc0$00.00%−67,293−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−64,978−100.0%Sold out
Financial Enhancement Group LLC0$00.00%−41,818−100.0%Sold out
Vontobel Holding Ltd.0$00.00%−40,000−100.0%Sold out
Belvedere Trading LLC0$00.00%−24,011−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−21,500−100.0%Sold out
CM Wealth Advisors LLC0$00.00%−17,285−100.0%Sold out
Public Employees Retirement System of Ohio0$00.00%−15,014−100.0%Sold out
Engineers Gate Manager LP0$00.00%−9,278−100.0%Sold out
TCI Wealth Advisors, Inc.0$00.00%−129−100.0%Sold out