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Karyopharm Therapeutics Inc.

KPTI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001503802

In the last 90 days, Karyopharm Therapeutics Inc. insiders filed 0 open-market purchases and 2 sales; 96 institutions reported holding it in 13F filings for Q2 2026, worth $206.8M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Karyopharm Therapeutics Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
87
−4 vs. Q3 2024
Shares held
60.9M
+1.50M (+2.5%) vs. Q3 2024
Total value
$41.2M
−$8.02M (−16.3%) vs. Q3 2024
New holders
14
22 more added
Sold out
18
23 more reduced

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KPTI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 87 institutions
Q1 2021: 171 institutionsQ2 2021: 154 institutionsQ3 2021: 134 institutionsQ4 2021: 143 institutionsQ1 2022: 139 institutionsQ2 2022: 150 institutionsQ3 2022: 147 institutionsQ4 2022: 155 institutionsQ1 2023: 132 institutionsQ2 2023: 138 institutionsQ3 2023: 120 institutionsQ4 2023: 120 institutionsQ1 2024: 114 institutionsQ2 2024: 114 institutionsQ3 2024: 91 institutionsQ4 2024: 87 institutionsQ1 2025: 50 institutionsQ2 2025: 50 institutionsQ3 2025: 52 institutionsQ4 2025: 68 institutionsQ1 2026: 77 institutionsQ2 2026: 96 institutions
Value heldQ4 2024: $41.2M
Q1 2021: $637.1MQ2 2021: $608.7MQ3 2021: $334.4MQ4 2021: $347.5MQ1 2022: $501.8MQ2 2022: $302.8MQ3 2022: $364.1MQ4 2022: $334.4MQ1 2023: $340.1MQ2 2023: $145.0MQ3 2023: $102.8MQ4 2023: $63.5MQ1 2024: $113.0MQ2 2024: $58.6MQ3 2024: $49.2MQ4 2024: $41.2MQ1 2025: $13.7MQ2 2025: $19.0MQ3 2025: $19.5MQ4 2025: $69.6MQ1 2026: $98.4MQ2 2026: $206.8M
Institutions holding KPTI and their total value by quarter
QuarterHoldersValue
Q2 202696$206.8M
Q1 202677$98.4M
Q4 202568$69.6M
Q3 202552$19.5M
Q2 202550$19.0M
Q1 202550$13.7M
Q4 202487$41.2M
Q3 202491$49.2M
Q2 2024114$58.6M
Q1 2024114$113.0M
Q4 2023120$63.5M
Q3 2023120$102.8M
Q2 2023138$145.0M
Q1 2023132$340.1M
Q4 2022155$334.4M
Q3 2022147$364.1M
Q2 2022150$302.8M
Q1 2022139$501.8M
Q4 2021143$347.5M
Q3 2021134$334.4M
Q2 2021154$608.7M
Q1 2021171$637.1M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Karyopharm Therapeutics Inc.; share changes are against Q3 2024.

Institutions holding KPTI in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Founders Capital Management0$00.00%−2,000−100.0%Sold out
Golden State Equity Partners0$00.00%−1,800−100.0%Sold out
Lazard Asset Management LLC0$00.00%−1,570−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−538−100.0%Sold out
AdvisorNet Financial, Inc0$00.00%−200−100.0%Sold out