Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 354
- +1 vs. Q2 2024
- Shares held
- 157.5M
- +24.6M (+18.5%) vs. Q2 2024
- Total value
- $6.31B
- −$23.0M (−0.4%) vs. Q2 2024
- New holders
- 53
- 131 more added
- Sold out
- 52
- 107 more reduced
4 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| UBS Oconnor LLC | 36,957 | $1.48M | 0.04% | −5,638−13.2% | Reduced |
| Capital Counsel LLC | 37,080 | $1.49M | 0.06% | 00.0% | Unchanged |
| Guggenheim Capital LLC | 37,159 | $1.49M | 0.01% | +1,770+5.0% | Added |
| Profund Advisors LLC | 37,596 | $1.51M | 0.06% | +7,613+25.4% | Added |
| Arizona State Retirement System | 37,827 | $1.52M | 0.01% | +1,105+3.0% | Added |
| DCF Advisers, LLC | 39,500 | $1.58M | 0.81% | +16,500+71.7% | Added |
| Baillie Gifford & Co | 39,581 | $1.59M | 0.00% | −220,673−84.8% | Reduced |
| Great West Life Assurance Co | 39,835 | $1.60M | 0.00% | −5,713−12.5% | Reduced |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.68M | 0.20% | 00.0% | Unchanged |
| LPL Financial LLC | 42,620 | $1.71M | 0.00% | −8,794−17.1% | Reduced |
| Handelsbanken Fonder AB | 43,011 | $1.72M | 0.01% | +9,100+26.8% | Added |
| Private Advisor Group, LLC | 43,787 | $1.75M | 0.01% | −2,639−5.7% | Reduced |
| Algert Global LLC | 45,430 | $1.82M | 0.05% | −29,920−39.7% | Reduced |
| Blair William & Co | 46,651 | $1.87M | 0.01% | +21,389+84.7% | Added |
| State of New Jersey Common Pension Fund D | 51,775 | $2.07M | 0.01% | −3,574−6.5% | Reduced |
| Alliancebernstein L.P. | 52,162 | $2.09M | 0.00% | +894+1.7% | Added |
| Erste Asset Management GmbH | 51,300 | $2.10M | 0.03% | 00.0% | Unchanged |
| Jefferies Financial Group Inc. | 52,781 | $2.11M | 0.03% | −9,419−15.1% | Reduced |
| Tudor Investment Corp Et Al | 53,479 | $2.14M | 0.02% | +40,381+308.3% | Added |
| Van Eck Associates Corp | 59,006 | $2.27M | 0.00% | +8,742+17.4% | Added |
| Teacher Retirement System of Texas | 56,699 | $2.27M | 0.01% | +4,147+7.9% | Added |
| Public Employees Retirement System of Ohio | 56,825 | $2.28M | 0.01% | +1,529+2.8% | Added |
| Susquehanna International Group, LLP | 57,239 | $2.29M | 0.00% | −38,619−40.3% | Reduced |
| Schroder Investment Management Group | 56,222 | $2.30M | 0.00% | 00.0% | Unchanged |
| Envestnet Asset Management Inc | 58,814 | $2.36M | 0.00% | −18,601−24.0% | Reduced |
| Janus Henderson Group PLC | 58,977 | $2.36M | 0.00% | 00.0% | Unchanged |
| NEOS Investment Management LLC | 59,244 | $2.37M | 0.07% | +14,186+31.5% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $2.39M | 0.01% | 00.0% | Unchanged |
| HBK Investments L P | 60,000 | $2.40M | 0.04% | +60,000 | New |
| Sphera Funds Management Ltd. | 63,821 | $2.56M | 0.42% | −76,417−54.5% | Reduced |
| Neuberger Berman Group LLC | 64,874 | $2.60M | 0.00% | +50,562+353.3% | Added |
| Treasurer of the State of North Carolina | 68,363 | $2.74M | 0.01% | +5,250+8.3% | Added |
| Ensign Peak Advisors, Inc | 69,880 | $2.80M | 0.00% | +1,610+2.4% | Added |
| Citigroup Inc | 70,295 | $2.82M | 0.00% | −6,323−8.3% | Reduced |
| Liontrust Investment Partners LLP | 59,644 | $2.84M | 0.04% | 00.0% | Unchanged |
| Deutsche Bank AG | 74,874 | $3.00M | 0.00% | +65,778+723.2% | Added |
| Davenport & Co LLC | 75,598 | $3.03M | 0.02% | −5,080−6.3% | Reduced |
| Commerce Bank | 77,553 | $3.11M | 0.02% | +1,211+1.6% | Added |
| Engineers Gate Manager LP | 78,874 | $3.16M | 0.06% | +62,554+383.3% | Added |
| HealthInvest Partners AB | 82,691 | $3.31M | 1.56% | +42,000+103.2% | Added |
| Granite Investment Partners, LLC | 85,793 | $3.44M | 0.15% | −28,297−24.8% | Reduced |
| State of Wisconsin Investment Board | 86,166 | $3.45M | 0.01% | −1,534−1.7% | Reduced |
| Prudential Financial Inc | 90,017 | $3.61M | 0.01% | +74,300+472.7% | Added |
| Dimensional Fund Advisors LP | 94,332 | $3.78M | 0.00% | +5,586+6.3% | Added |
| DekaBank Deutsche Girozentrale | 93,807 | $3.80M | 0.01% | 00.0% | Unchanged |
| Voya Investment Management LLC | 95,821 | $3.84M | 0.00% | +702+0.7% | Added |
| Cutter Capital Management, LP | 97,300 | $3.90M | 1.15% | −62,866−39.3% | Reduced |
| Eisler Capital (US) LLC | 117,565 | $4.71M | 0.87% | +101,295+622.6% | Added |
| Nicola Wealth Management Ltd. | 87,000 | $4.71M | 0.37% | +13,000+17.6% | Added |
| Amundi | 128,299 | $4.85M | 0.00% | −1,176−0.9% | Reduced |
| Walleye Capital LLC | 124,116 | $4.97M | 0.05% | +26,245+26.8% | Added |
| California State Teachers Retirement System | 126,180 | $5.05M | 0.01% | −3,036−2.3% | Reduced |
| Squarepoint Ops LLC | 127,341 | $5.10M | 0.02% | −309,477−70.8% | Reduced |
| Russell Investments Group, Ltd. | 128,469 | $5.15M | 0.01% | −4,267−3.2% | Reduced |
| Swedbank AB | 129,373 | $5.18M | 0.01% | 00.0% | Unchanged |
| Trexquant Investment LP | 130,858 | $5.24M | 0.07% | +100,772+334.9% | Added |
| Peregrine Capital Management LLC | 131,630 | $5.27M | 0.16% | −394−0.3% | Reduced |
| D. E. Shaw & Co., Inc. | 145,091 | $5.81M | 0.01% | −45,690−23.9% | Reduced |
| Tang Capital Management LLC | 150,000 | $6.01M | 0.43% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 151,055 | $6.05M | 0.01% | 00.0% | Unchanged |
| BLB&B Advisors, LLC | 152,250 | $6.10M | 0.31% | −1,500−1.0% | Reduced |
| Sonora Investment Management Group, LLC | 153,175 | $6.14M | 0.45% | +2,361+1.6% | Added |
| Legal & General Group Plc | 157,287 | $6.30M | 0.00% | +9,643+6.5% | Added |
| Kennedy Capital Management, Inc. | 162,076 | $6.49M | 0.14% | −92,267−36.3% | Reduced |
| UBS Group AG | 167,880 | $6.73M | 0.00% | +15,208+10.0% | Added |
| Alyeska Investment Group, L.P. | 168,951 | $6.77M | 0.03% | +168,951 | New |
| BNP Paribas Arbitrage, SA | 175,328 | $7.02M | 0.01% | −10,616−5.7% | Reduced |
| Jane Street Group, LLC | 176,560 | $7.07M | 0.01% | −2,686−1.5% | Reduced |
| Stifel Financial Corp | 182,505 | $7.31M | 0.01% | −33,635−15.6% | Reduced |
| Altrinsic Global Advisors LLC | 182,734 | $7.32M | 0.31% | −5,097−2.7% | Reduced |
| SEI Investments Co | 189,837 | $7.60M | 0.01% | +57,526+43.5% | Added |
| Renaissance Technologies LLC | 190,514 | $7.63M | 0.01% | −59,000−23.6% | Reduced |
| Sicart Associates LLC | 191,523 | $7.67M | 2.69% | 00.0% | Unchanged |
| Rhenman & Partners Asset Management AB | 195,000 | $7.81M | 0.63% | +65,000+50.0% | Added |
| Nikko Asset Management Americas, Inc. | 196,114 | $7.86M | 0.09% | −3,117−1.6% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 196,114 | $7.86M | 0.01% | −3,117−1.6% | Reduced |
| Rhumbline Advisers | 196,942 | $7.89M | 0.01% | +18,853+10.6% | Added |
| New York State Common Retirement Fund | 198,759 | $7.96M | 0.01% | −16,957−7.9% | Reduced |
| Rafferty Asset Management, LLC | 198,759 | $7.96M | 0.03% | +29,903+17.7% | Added |
| International Assets Investment Management, LLC | 328,772 | $8.21M | 0.04% | +319,065+3,287.0% | Added |
| Sector Gamma AS | 210,842 | $8.45M | 2.56% | +40,842+24.0% | Added |
| California Public Employees Retirement System | 211,756 | $8.48M | 0.01% | +15,272+7.8% | Added |
| Bank of Montreal | 213,883 | $8.74M | 0.00% | −6,635−3.0% | Reduced |
| Orion Investment Co | 218,525 | $8.75M | 3.42% | −450.0% | Reduced |
| Baker Bros. Advisors LP | 223,470 | $8.95M | 0.09% | +223,470 | New |
| Driehaus Capital Management LLC | 229,969 | $9.21M | 0.08% | +229,969 | New |
| Twinbeech Capital LP | 235,477 | $9.43M | 0.18% | +235,477 | New |
| Goldman Sachs Group Inc | 235,710 | $9.44M | 0.00% | −92,595−28.2% | Reduced |
| CI Private Wealth, LLC | 237,076 | $9.50M | 0.01% | −30,961−11.6% | Reduced |
| Siren, L.L.C. | 250,000 | $10.0M | 0.50% | +250,000 | New |
| Privium Fund Management B.V. | 250,744 | $10.0M | 2.50% | +3,477+1.4% | Added |
| Great Point Partners LLC | 255,000 | $10.2M | 3.08% | −75,000−22.7% | Reduced |
| Swiss National Bank | 256,600 | $10.3M | 0.01% | −1,400−0.5% | Reduced |
| UBS Asset Management Americas Inc | 285,697 | $11.4M | 0.00% | −34,593−10.8% | Reduced |
| C WorldWide Group Holding A/S | 300,000 | $12.0M | 0.12% | 00.0% | Unchanged |
| Standard Life Aberdeen plc | 303,274 | $12.1M | 0.02% | +56,357+22.8% | Added |
| Nuveen Asset Management, LLC | 304,779 | $12.2M | 0.00% | −105,625−25.7% | Reduced |
| Manufacturers Life Insurance Company, The | 308,947 | $12.4M | 0.01% | +34,097+12.4% | Added |
| Wells Fargo & Company | 342,154 | $13.7M | 0.00% | −24,407−6.7% | Reduced |
| Groupama Asset Managment | 416,060 | $13.8M | 0.36% | +36,084+9.5% | Added |