Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 357
- −1 vs. Q1 2024
- Shares held
- 143.3M
- +1.29M (+0.9%) vs. Q1 2024
- Total value
- $6.83B
- +$666.0M (+10.8%) vs. Q1 2024
- New holders
- 52
- 120 more added
- Sold out
- 53
- 132 more reduced
3 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Creative Planning | 26,860 | $1.28M | 0.00% | −145−0.5% | Reduced |
| Profund Advisors LLC | 29,983 | $1.43M | 0.05% | −1,587−5.0% | Reduced |
| Trexquant Investment LP | 30,086 | $1.43M | 0.02% | −55,266−64.8% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 31,155 | $1.48M | 0.00% | +3,011+10.7% | Added |
| Handelsbanken Fonder AB | 33,911 | $1.62M | 0.01% | 00.0% | Unchanged |
| Grandfield & Dodd, LLC | 34,053 | $1.62M | 0.10% | +279+0.8% | Added |
| Cubist Systematic Strategies, LLC | 35,311 | $1.68M | 0.03% | −242,480−87.3% | Reduced |
| Guggenheim Capital LLC | 35,389 | $1.69M | 0.01% | −461−1.3% | Reduced |
| Arizona State Retirement System | 36,722 | $1.75M | 0.01% | +1,235+3.5% | Added |
| Capital Counsel LLC | 37,080 | $1.77M | 0.08% | −2,500−6.3% | Reduced |
| HealthInvest Partners AB | 40,691 | $1.94M | 1.18% | −23,100−36.2% | Reduced |
| NJ State Employees Deferred Compensation Plan | 42,000 | $2.00M | 0.25% | 00.0% | Unchanged |
| UBS Oconnor LLC | 42,595 | $2.03M | 0.06% | +183+0.4% | Added |
| Susquehanna Portfolio Strategies, LLC | 43,028 | $2.05M | 0.08% | −87,958−67.2% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 44,256 | $2.11M | 0.01% | +44,256 | New |
| NEOS Investment Management LLC | 45,058 | $2.15M | 0.09% | +7,755+20.8% | Added |
| Susquehanna Fundamental Investments, LLC | 45,574 | $2.17M | 0.05% | 00.0% | Unchanged |
| Great West Life Assurance Co | 45,548 | $2.17M | 0.00% | +3,668+8.8% | Added |
| Private Advisor Group, LLC | 46,426 | $2.21M | 0.01% | −1,550−3.2% | Reduced |
| Tower Research Capital LLC (TRC) | 49,986 | $2.38M | 0.04% | +45,123+927.9% | Added |
| Van Eck Associates Corp | 50,264 | $2.40M | 0.00% | −40,837−44.8% | Reduced |
| Erste Asset Management GmbH | 51,300 | $2.42M | 0.03% | 00.0% | Unchanged |
| DRW Securities, LLC | 50,956 | $2.43M | 0.15% | +50,956 | New |
| Alliancebernstein L.P. | 51,268 | $2.44M | 0.00% | −139,887−73.2% | Reduced |
| LPL Financial LLC | 51,414 | $2.45M | 0.00% | −28,308−35.5% | Reduced |
| Bank of Nova Scotia | 51,879 | $2.47M | 0.00% | +51,879 | New |
| Teacher Retirement System of Texas | 52,552 | $2.50M | 0.01% | +23,816+82.9% | Added |
| Public Employees Retirement System of Ohio | 55,296 | $2.64M | 0.01% | +803+1.5% | Added |
| State of New Jersey Common Pension Fund D | 55,349 | $2.64M | 0.01% | −26,498−32.4% | Reduced |
| Schroder Investment Management Group | 56,222 | $2.68M | 0.00% | −59,436−51.4% | Reduced |
| Janus Henderson Group PLC | 58,977 | $2.81M | 0.00% | −740−1.2% | Reduced |
| Liontrust Investment Partners LLP | 59,644 | $2.84M | 0.04% | −228,900−79.3% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $2.85M | 0.01% | 00.0% | Unchanged |
| GTS Securities LLC | 60,930 | $2.90M | 0.06% | +60,930 | New |
| Jefferies Financial Group Inc. | 62,200 | $2.96M | 0.06% | −130,880−67.8% | Reduced |
| Artia Global Partners LP | 62,479 | $2.98M | 0.76% | +62,479 | New |
| Treasurer of the State of North Carolina | 63,113 | $3.01M | 0.01% | −469−0.7% | Reduced |
| Simplex Trading, LLC | 63,347 | $3.02M | 0.10% | +54,817+642.6% | Added |
| Ensign Peak Advisors, Inc | 68,270 | $3.25M | 0.01% | +14,950+28.0% | Added |
| Algert Global LLC | 75,350 | $3.59M | 0.12% | +45,108+149.2% | Added |
| Commerce Bank | 76,342 | $3.64M | 0.02% | −6,091−7.4% | Reduced |
| Citigroup Inc | 76,618 | $3.65M | 0.00% | −146,325−65.6% | Reduced |
| Envestnet Asset Management Inc | 77,415 | $3.69M | 0.00% | −52,557−40.4% | Reduced |
| Two Sigma Securities, LLC | 80,198 | $3.82M | 0.18% | +69,076+621.1% | Added |
| Davenport & Co LLC | 80,678 | $3.85M | 0.02% | −3,250−3.9% | Reduced |
| State of Wisconsin Investment Board | 87,700 | $4.18M | 0.01% | −4,115−4.5% | Reduced |
| Dimensional Fund Advisors LP | 88,746 | $4.23M | 0.00% | −20,557−18.8% | Reduced |
| DekaBank Deutsche Girozentrale | 93,807 | $4.42M | 0.01% | 00.0% | Unchanged |
| Avidity Partners Management LP | 93,000 | $4.43M | 0.19% | −37,000−28.5% | Reduced |
| Voya Investment Management LLC | 95,119 | $4.53M | 0.00% | +40,923+75.5% | Added |
| Susquehanna International Group, LLP | 95,858 | $4.57M | 0.01% | −43,203−31.1% | Reduced |
| Walleye Capital LLC | 97,871 | $4.66M | 0.05% | +8,741+9.8% | Added |
| Nicola Wealth Management Ltd. | 74,000 | $4.83M | 0.43% | +18,000+32.1% | Added |
| Granite Investment Partners, LLC | 114,090 | $5.44M | 0.23% | −2,054−1.8% | Reduced |
| Verition Fund Management LLC | 120,814 | $5.76M | 0.04% | −165,133−57.7% | Reduced |
| Amundi | 129,475 | $5.90M | 0.00% | −11,301−8.0% | Reduced |
| Millennium Management LLC | 128,215 | $6.11M | 0.01% | −454,964−78.0% | Reduced |
| California State Teachers Retirement System | 129,216 | $6.16M | 0.01% | −2,602−2.0% | Reduced |
| Swedbank AB | 129,373 | $6.17M | 0.01% | −13,268−9.3% | Reduced |
| Rhenman & Partners Asset Management AB | 130,000 | $6.20M | 0.59% | +130,000 | New |
| Peregrine Capital Management LLC | 132,024 | $6.29M | 0.18% | +13,426+11.3% | Added |
| SEI Investments Co | 132,311 | $6.31M | 0.01% | +52,424+65.6% | Added |
| Russell Investments Group, Ltd. | 132,736 | $6.33M | 0.01% | −20,679−13.5% | Reduced |
| Sonora Investment Management Group, LLC | 150,814 | $6.54M | 0.51% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 137,210 | $6.54M | 0.02% | −149,392−52.1% | Reduced |
| Sphera Funds Management Ltd. | 140,238 | $6.68M | 1.09% | +140,238 | New |
| Legal & General Group Plc | 147,644 | $7.04M | 0.00% | −1,844−1.2% | Reduced |
| Tang Capital Management LLC | 150,000 | $7.15M | 0.73% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 151,055 | $7.20M | 0.01% | −4,090−2.6% | Reduced |
| UBS Group AG | 152,672 | $7.28M | 0.00% | −19,091−11.1% | Reduced |
| BLB&B Advisors, LLC | 153,750 | $7.33M | 0.40% | +7,650+5.2% | Added |
| HRT Financial LP | 159,685 | $7.61M | 0.04% | +93,182+140.1% | Added |
| Caption Management, LLC | 160,000 | $7.63M | 0.81% | +160,000 | New |
| Cutter Capital Management, LP | 160,166 | $7.63M | 2.33% | −129,200−44.6% | Reduced |
| Parkman Healthcare Partners LLC | 161,705 | $7.71M | 1.05% | +20,206+14.3% | Added |
| Rafferty Asset Management, LLC | 168,856 | $8.05M | 0.03% | −39,613−19.0% | Reduced |
| Sector Gamma AS | 170,000 | $8.10M | 3.03% | −5,507−3.1% | Reduced |
| Marshall Wace, LLP | 173,199 | $8.25M | 0.01% | +157,756+1,021.5% | Added |
| Rhumbline Advisers | 178,089 | $8.49M | 0.01% | −1,330−0.7% | Reduced |
| Jane Street Group, LLC | 179,246 | $8.54M | 0.01% | +61,114+51.7% | Added |
| BNP Paribas Arbitrage, SA | 185,944 | $8.86M | 0.01% | −8,415−4.3% | Reduced |
| Altrinsic Global Advisors LLC | 187,831 | $8.95M | 0.40% | −7,033−3.6% | Reduced |
| D. E. Shaw & Co., Inc. | 190,781 | $9.09M | 0.01% | +30,299+18.9% | Added |
| Sicart Associates LLC | 191,523 | $9.13M | 3.50% | −2,470−1.3% | Reduced |
| California Public Employees Retirement System | 196,484 | $9.36M | 0.01% | −7,461−3.7% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 199,231 | $9.50M | 0.01% | −21,030−9.5% | Reduced |
| Nikko Asset Management Americas, Inc. | 199,231 | $9.50M | 0.11% | −21,030−9.5% | Reduced |
| Zimmer Partners, LP | 200,000 | $9.53M | 0.18% | −70,300−26.0% | Reduced |
| ExodusPoint Capital Management, LP | 209,194 | $9.97M | 0.11% | −6,699−3.1% | Reduced |
| New York State Common Retirement Fund | 215,716 | $10.3M | 0.01% | +83,006+62.5% | Added |
| Stifel Financial Corp | 216,140 | $10.3M | 0.01% | −26,319−10.9% | Reduced |
| Orion Investment Co | 218,570 | $10.4M | 4.15% | +218,570 | New |
| Bank of Montreal | 220,518 | $10.5M | 0.01% | −2,300−1.0% | Reduced |
| Tocqueville Asset Management L.P. | 225,070 | $10.7M | 0.18% | +65,690+41.2% | Added |
| Privium Fund Management B.V. | 247,267 | $11.2M | 2.85% | +20,274+8.9% | Added |
| Standard Life Aberdeen plc | 246,917 | $11.8M | 0.02% | +27,496+12.5% | Added |
| Renaissance Technologies LLC | 249,514 | $11.9M | 0.02% | +69,800+38.8% | Added |
| Integral Health Asset Management, LLC | 250,000 | $11.9M | 1.19% | +250,000 | New |
| Kennedy Capital Management, Inc. | 254,343 | $12.1M | 0.26% | +4,816+1.9% | Added |
| Swiss National Bank | 258,000 | $12.3M | 0.01% | +3,100+1.2% | Added |