Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 312
- +12 vs. Q2 2023
- Shares held
- 139.7M
- +6.44M (+4.8%) vs. Q2 2023
- Total value
- $6.35B
- +$878.1M (+16.1%) vs. Q2 2023
- New holders
- 39
- 101 more added
- Sold out
- 27
- 103 more reduced
5 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Massachusetts Financial Services Co | 5,769 | $261.7K | 0.00% | −20,760−78.3% | Reduced |
| PEAK6 Investments LLC | 6,502 | $294.9K | 0.01% | +6,502 | New |
| Lazard Asset Management LLC | 6,557 | $296.0K | 0.00% | +1,420+27.6% | Added |
| Cambridge Investment Research Advisors, Inc. | 6,647 | $302.0K | 0.00% | −827−11.1% | Reduced |
| Baird Financial Group, Inc. | 6,774 | $307.3K | 0.00% | +185+2.8% | Added |
| JustInvest LLC | 6,778 | $307.4K | 0.01% | −389−5.4% | Reduced |
| Castle Rock Wealth Management, LLC | 6,972 | $327.0K | 0.11% | −400−5.4% | Reduced |
| Virtus ETF Advisers LLC | 7,457 | $338.3K | 0.21% | −961−11.4% | Reduced |
| Stephens Inc | 7,485 | $339.5K | 0.01% | −21−0.3% | Reduced |
| Wrapmanager Inc | 7,527 | $341.4K | 0.11% | −466−5.8% | Reduced |
| Utah Retirement Systems | 7,700 | $349.3K | 0.00% | +200+2.7% | Added |
| Ameriprise Financial Inc | 7,815 | $354.5K | 0.00% | −1,445−15.6% | Reduced |
| Midwest Professional Planners, LTD. | 7,825 | $354.9K | 0.16% | +1,232+18.7% | Added |
| MetLife Investment Management | 7,926 | $359.5K | 0.00% | +4+0.1% | Added |
| Gotham Asset Management, LLC | 8,088 | $366.9K | 0.01% | +23+0.3% | Added |
| The PNC Financial Services Group, Inc. | 8,176 | $370.9K | 0.00% | −195−2.3% | Reduced |
| Vontobel Holding Ltd. | 8,216 | $372.7K | 0.00% | −350−4.1% | Reduced |
| Franklin Resources Inc | 8,449 | $383.2K | 0.00% | −722−7.9% | Reduced |
| Nicollet Investment Management, Inc. | 8,668 | $393.0K | 0.18% | −90−1.0% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 8,803 | $399.3K | 0.04% | +8,803 | New |
| Corton Capital Inc. | 8,895 | $403.5K | 0.20% | +1,966+28.4% | Added |
| AtonRa Partners | 9,329 | $423.2K | 0.89% | −2,307−19.8% | Reduced |
| ProShare Advisors LLC | 9,370 | $425.0K | 0.00% | +112+1.2% | Added |
| Deutsche Bank AG | 9,489 | $430.4K | 0.00% | +63+0.7% | Added |
| Waddell & Associates, LLC | 10,042 | $455.5K | 0.07% | 00.0% | Unchanged |
| Captrust Financial Advisors | 10,266 | $465.7K | 0.00% | +939+10.1% | Added |
| Maryland State Retirement & Pension System | 10,950 | $496.7K | 0.01% | 00.0% | Unchanged |
| Oppenheimer Asset Management Inc. | 10,968 | $497.5K | 0.01% | −51−0.5% | Reduced |
| E Fund Management Co., Ltd. | 11,096 | $503.0K | 0.04% | +108+1.0% | Added |
| Plancorp, LLC | 11,155 | $506.0K | 0.03% | 00.0% | Unchanged |
| HighTower Advisors, LLC | 11,104 | $506.0K | 0.00% | −145−1.3% | Reduced |
| Northwestern Mutual Wealth Management Co | 11,167 | $506.5K | 0.00% | +4,522+68.1% | Added |
| Acuta Capital Partners, LLC | 11,300 | $512.6K | 0.37% | +11,300 | New |
| Advisor Group Holdings, Inc. | 11,448 | $519.2K | 0.00% | +2,687+30.7% | Added |
| Brown Advisory Inc | 11,725 | $531.8K | 0.00% | +138+1.2% | Added |
| Mirae Asset Global Investments Co., Ltd. | 12,042 | $546.2K | 0.00% | +129+1.1% | Added |
| Bleakley Financial Group, LLC | 12,198 | $553.3K | 0.02% | −340−2.7% | Reduced |
| Sawtooth Solutions, LLC | 12,198 | $553.3K | 0.02% | −267−2.1% | Reduced |
| Raymond James Financial Services Advisors, Inc. | 12,257 | $556.0K | 0.00% | −1,885−13.3% | Reduced |
| American Century Companies Inc | 12,982 | $588.9K | 0.00% | +375+3.0% | Added |
| Horizon Kinetics Asset Management LLC | 13,000 | $589.7K | 0.01% | 00.0% | Unchanged |
| Centiva Capital, LP | 13,307 | $603.6K | 0.03% | +13,307 | New |
| US Bancorp | 13,358 | $605.9K | 0.00% | −662−4.7% | Reduced |
| Westmount Partners, LLC | 13,462 | $610.6K | 0.27% | 00.0% | Unchanged |
| Fred Alger Management, LLC | 13,566 | $615.4K | 0.00% | +13,566 | New |
| North Star Asset Management Inc | 13,640 | $618.7K | 0.04% | 00.0% | Unchanged |
| Martingale Asset Management L P | 14,034 | $636.6K | 0.01% | 00.0% | Unchanged |
| Teachers Retirement System of the State of Kentucky | 14,118 | $640.0K | 0.01% | +14,118 | New |
| Graham Capital Management, L.P. | 14,488 | $657.2K | 0.02% | +14,488 | New |
| Tanaka Capital Management Inc | 14,612 | $663.0K | 1.89% | +7,500+105.5% | Added |
| Victory Capital Management Inc | 15,436 | $700.2K | 0.00% | +348+2.3% | Added |
| Neuberger Berman Group LLC | 15,534 | $704.6K | 0.00% | +328+2.2% | Added |
| Natixis Advisors, L.P. | 15,919 | $722.0K | 0.00% | −279−1.7% | Reduced |
| Blair William & Co | 16,344 | $741.4K | 0.00% | −40−0.2% | Reduced |
| XTX Topco Ltd | 16,352 | $741.7K | 0.13% | +16,352 | New |
| Campbell & CO Investment Adviser LLC | 16,547 | $750.6K | 0.09% | +16,547 | New |
| NBT Bank N A | 17,050 | $773.4K | 0.07% | +17,050 | New |
| Xponance, Inc. | 17,836 | $809.0K | 0.01% | −430−2.4% | Reduced |
| Mariner, LLC | 17,888 | $811.4K | 0.00% | +514+3.0% | Added |
| Public Employees Retirement Association of Colorado | 17,906 | $812.0K | 0.00% | −1,698−8.7% | Reduced |
| Koss-Olinger Consulting, LLC | 17,907 | $812.0K | 0.12% | 00.0% | Unchanged |
| Point72 Middle East FZE | 18,313 | $830.7K | 0.05% | +2,009+12.3% | Added |
| PDT Partners, LLC | 19,537 | $886.2K | 0.11% | +1,039+5.6% | Added |
| Twin Tree Management, LP | 20,441 | $927.2K | 0.03% | +20,441 | New |
| Commonwealth Equity Services, LLC | 21,470 | $974.0K | 0.00% | +897+4.4% | Added |
| Creative Planning | 21,572 | $978.5K | 0.00% | +6,329+41.5% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 23,339 | $1.06M | 0.00% | +3,327+16.6% | Added |
| Handelsbanken Fonder AB | 23,811 | $1.08M | 0.01% | −6,900−22.5% | Reduced |
| Bard Financial Services, Inc. | 25,550 | $1.16M | 0.14% | −5,750−18.4% | Reduced |
| Bokf, NA | 26,974 | $1.19M | 0.03% | −31,776−54.1% | Reduced |
| Amalgamated Bank | 29,086 | $1.32M | 0.01% | −373−1.3% | Reduced |
| EAM Investors, LLC | 29,262 | $1.33M | 0.26% | +29,262 | New |
| Janney Montgomery Scott LLC | 29,618 | $1.34M | 0.01% | −1,485−4.8% | Reduced |
| Estate Counselors, LLC | 32,800 | $1.49M | 0.20% | −310−0.9% | Reduced |
| Grandfield & Dodd, LLC | 32,862 | $1.49M | 0.11% | +183+0.6% | Added |
| Virginia Retirement Systems Et Al | 32,900 | $1.49M | 0.01% | −1,700−4.9% | Reduced |
| Principal Financial Group Inc | 34,651 | $1.57M | 0.00% | +1,381+4.2% | Added |
| Profund Advisors LLC | 35,470 | $1.61M | 0.09% | −814−2.2% | Reduced |
| Teacher Retirement System of Texas | 36,578 | $1.66M | 0.01% | +1,675+4.8% | Added |
| Arizona State Retirement System | 36,668 | $1.66M | 0.01% | +530+1.5% | Added |
| Great West Life Assurance Co | 36,801 | $1.67M | 0.00% | +8,758+31.2% | Added |
| Comerica Bank | 39,948 | $1.81M | 0.01% | +39,410+7,325.3% | Added |
| Capital Counsel LLC | 40,230 | $1.82M | 0.10% | 00.0% | Unchanged |
| Guggenheim Capital LLC | 40,475 | $1.84M | 0.02% | −11,451−22.1% | Reduced |
| Nicola Wealth Management Ltd. | 30,000 | $1.84M | 0.20% | +30,000 | New |
| SG Americas Securities, LLC | 41,571 | $1.89M | 0.03% | +22,078+113.3% | Added |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.91M | 0.29% | 00.0% | Unchanged |
| International Biotechnology Trust PLC | 43,000 | $1.95M | 0.66% | 00.0% | Unchanged |
| Granite Bay Wealth Management, LLC | 47,579 | $1.97M | 0.02% | +47,579 | New |
| Algert Global LLC | 45,522 | $2.06M | 0.10% | −3,730−7.6% | Reduced |
| Ensign Peak Advisors, Inc | 46,310 | $2.10M | 0.00% | 00.0% | Unchanged |
| Boulder Hill Capital Management LP | 46,500 | $2.11M | 1.31% | +46,500 | New |
| HighVista Strategies LLC | 48,520 | $2.20M | 1.02% | +48,520 | New |
| Private Advisor Group, LLC | 48,618 | $2.21M | 0.02% | +788+1.6% | Added |
| Erste Asset Management GmbH | 51,300 | $2.37M | 0.04% | 00.0% | Unchanged |
| Voya Investment Management LLC | 57,673 | $2.62M | 0.00% | −1,823−3.1% | Reduced |
| Public Employees Retirement System of Ohio | 58,000 | $2.63M | 0.01% | −6,426−10.0% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $2.71M | 0.02% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 59,806 | $2.71M | 0.00% | +40.0% | Added |
| Schonfeld Strategic Advisors LLC | 61,548 | $2.79M | 0.03% | +22,504+57.6% | Added |