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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q2 2023

Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
305
−10 vs. Q1 2023
Shares held
136.5M
+5.40M (+4.1%) vs. Q1 2023
Total value
$5.60B
+$907.9M (+19.3%) vs. Q1 2023
New holders
33
97 more added
Sold out
43
111 more reduced

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 305 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ2 2023: $5.60B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2023.

Institutions holding IONS in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Seven Eight Capital, LP6,178$253.5K0.04%+6,178New
Baird Financial Group, Inc.6,589$270.3K0.00%−194−2.9%Reduced
Midwest Professional Planners, LTD.6,593$270.5K0.12%+6,593New
Northwestern Mutual Wealth Management Co6,645$272.6K0.00%−257−3.7%Reduced
Corton Capital Inc.6,929$284.3K0.13%−2,111−23.4%Reduced
Tanaka Capital Management Inc7,112$292.0K0.79%00.0%Unchanged
JustInvest LLC7,167$294.1K0.01%+1,301+22.2%Added
Cambridge Investment Research Advisors, Inc.7,474$307.0K0.00%−1,000−11.8%Reduced
Utah Retirement Systems7,500$307.7K0.00%00.0%Unchanged
Stephens Inc7,506$308.0K0.01%+164+2.2%Added
Castle Rock Wealth Management, LLC7,372$311.0K0.11%−12,013−62.0%Reduced
MetLife Investment Management7,922$325.0K0.00%−178−2.2%Reduced
Wrapmanager Inc7,993$328.0K0.10%−680−7.8%Reduced
Gotham Asset Management, LLC8,065$330.9K0.01%−5,168−39.1%Reduced
The PNC Financial Services Group, Inc.8,371$343.5K0.00%−10−0.1%Reduced
Virtus ETF Advisers LLC8,418$345.4K0.20%+374+4.6%Added
Vontobel Holding Ltd.8,566$351.5K0.00%−1,250−12.7%Reduced
Nicollet Investment Management, Inc.8,758$359.0K0.16%+293+3.5%Added
Advisor Group Holdings, Inc.8,761$359.6K0.00%−774−8.1%Reduced
Franklin Resources Inc9,171$376.3K0.00%−1,229−11.8%Reduced
ProShare Advisors LLC9,258$379.9K0.00%−653−6.6%Reduced
Ameriprise Financial Inc9,260$379.9K0.00%+343+3.8%Added
Captrust Financial Advisors9,327$382.7K0.00%−131−1.4%Reduced
Deutsche Bank AG9,426$386.7K0.00%−36,300−79.4%Reduced
Waddell & Associates, LLC10,042$412.0K0.06%00.0%Unchanged
Maryland State Retirement & Pension System10,950$449.3K0.01%00.0%Unchanged
E Fund Management Co., Ltd.10,988$451.0K0.04%−384−3.4%Reduced
Oppenheimer Asset Management Inc.11,019$452.1K0.01%−36−0.3%Reduced
Plancorp, LLC11,155$457.7K0.02%−20.0%Reduced
HighTower Advisors, LLC11,249$461.0K0.00%−220−1.9%Reduced
Brown Advisory Inc11,587$475.4K0.00%+126+1.1%Added
AtonRa Partners11,636$477.4K0.74%−708−5.7%Reduced
Mirae Asset Global Investments Co., Ltd.11,913$489.4K0.00%−3,658−23.5%Reduced
Sawtooth Solutions, LLC12,465$511.4K0.01%+218+1.8%Added
Bleakley Financial Group, LLC12,538$514.4K0.02%+291+2.4%Added
American Century Companies Inc12,607$517.3K0.00%−556−4.2%Reduced
Horizon Kinetics Asset Management LLC13,000$533.4K0.01%00.0%Unchanged
Westmount Partners, LLC13,462$552.3K0.24%00.0%Unchanged
North Star Asset Management Inc13,640$559.6K0.03%−40−0.3%Reduced
US Bancorp14,020$575.2K0.00%−2,102−13.0%Reduced
Martingale Asset Management L P14,034$575.8K0.01%+91+0.7%Added
Raymond James Financial Services Advisors, Inc.14,142$580.2K0.00%−11,510−44.9%Reduced
Victory Capital Management Inc15,088$619.1K0.00%−351−2.3%Reduced
Neuberger Berman Group LLC15,206$623.9K0.00%+74+0.5%Added
Creative Planning15,243$625.4K0.00%+1,611+11.8%Added
SEI Investments Co15,310$628.2K0.00%−30,614−66.7%Reduced
Aigen Investment Management, LP16,019$657.3K0.10%+16,019New
Natixis Advisors, L.P.16,198$665.0K0.00%+122+0.8%Added
Point72 Middle East FZE16,304$669.0K0.04%+16,304New
Blair William & Co16,384$672.2K0.00%+1,740+11.9%Added
Mariner, LLC17,374$712.9K0.00%+10,853+166.4%Added
Koss-Olinger Consulting, LLC17,907$735.0K0.09%−361−2.0%Reduced
Xponance, Inc.18,266$749.5K0.01%+339+1.9%Added
PDT Partners, LLC18,498$759.0K0.10%+18,498New
SG Americas Securities, LLC19,493$800.0K0.01%+19,493New
Public Employees Retirement Association of Colorado19,604$804.0K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)20,012$821.1K0.00%00.0%Unchanged
Commonwealth Equity Services, LLC20,573$844.0K0.00%−65−0.3%Reduced
Canada Pension Plan Investment Board21,019$862.4K0.00%−57,600−73.3%Reduced
Allianz Asset Management GmbH23,100$947.8K0.00%−85,148−78.7%Reduced
Vestmark Advisory Solutions, Inc.23,623$969.3K0.04%+4,556+23.9%Added
Massachusetts Financial Services Co26,529$1.09M0.00%−624−2.3%Reduced
Great West Life Assurance Co28,043$1.16M0.00%+621+2.3%Added
Amalgamated Bank29,459$1.21M0.01%+351+1.2%Added
Handelsbanken Fonder AB30,711$1.26M0.01%+12,200+65.9%Added
Janney Montgomery Scott LLC31,103$1.28M0.00%−1,505−4.6%Reduced
Bard Financial Services, Inc.31,300$1.28M0.10%−525−1.6%Reduced
Van Eck Associates Corp31,361$1.29M0.00%+12,186+63.6%Added
Grandfield & Dodd, LLC32,679$1.34M0.09%+395+1.2%Added
Estate Counselors, LLC33,110$1.36M0.17%00.0%Unchanged
Principal Financial Group Inc33,270$1.37M0.00%−1,396−4.0%Reduced
Engineers Gate Manager LP34,047$1.40M0.05%−293−0.9%Reduced
Virginia Retirement Systems Et Al34,600$1.42M0.01%+11,700+51.1%Added
Teacher Retirement System of Texas34,903$1.43M0.01%−4,480−11.4%Reduced
Envestnet Asset Management Inc36,069$1.48M0.00%+580+1.6%Added
Arizona State Retirement System36,138$1.48M0.01%−905−2.4%Reduced
Profund Advisors LLC36,284$1.49M0.08%−125−0.3%Reduced
Tudor Investment Corp Et Al39,025$1.60M0.03%−33,552−46.2%Reduced
Schonfeld Strategic Advisors LLC39,044$1.60M0.01%−3,165−7.5%Reduced
Capital Counsel LLC40,230$1.65M0.09%00.0%Unchanged
NJ State Employees Deferred Compensation Plan42,000$1.72M0.25%00.0%Unchanged
International Biotechnology Trust PLC43,000$1.76M0.54%00.0%Unchanged
Ensign Peak Advisors, Inc46,310$1.90M0.00%00.0%Unchanged
Private Advisor Group, LLC47,830$1.96M0.02%−637−1.3%Reduced
Algert Global LLC49,252$2.02M0.09%−9,400−16.0%Reduced
Erste Asset Management GmbH51,300$2.11M0.04%00.0%Unchanged
Guggenheim Capital LLC51,926$2.13M0.02%−11,637−18.3%Reduced
Bokf, NA58,750$2.41M0.05%−1,511−2.5%Reduced
Voya Investment Management LLC59,496$2.44M0.00%+5,764+10.7%Added
Skandinaviska Enskilda Banken AB (publ)59,626$2.45M0.02%+40,770+216.2%Added
Janus Henderson Group PLC59,802$2.45M0.00%−57−0.1%Reduced
Treasurer of the State of North Carolina62,222$2.55M0.01%+480+0.8%Added
Public Employees Retirement System of Ohio64,426$2.64M0.01%−5,793−8.2%Reduced
Squarepoint Ops LLC67,809$2.78M0.02%−45,591−40.2%Reduced
Marshall Wace, LLP69,063$2.83M0.01%+69,063New
UBS Oconnor LLC72,059$2.96M0.06%−35,430−33.0%Reduced
PFS Investments Inc.72,791$2.99M0.05%+150.0%Added
Bank of Nova Scotia78,042$3.20M0.01%+36,636+88.5%Added
State of New Jersey Common Pension Fund D80,433$3.30M0.01%00.0%Unchanged
Citigroup Inc81,747$3.35M0.00%−103,226−55.8%Reduced