Skip to main content

Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q2 2023

Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
305
−10 vs. Q1 2023
Shares held
136.5M
+5.40M (+4.1%) vs. Q1 2023
Total value
$5.60B
+$907.9M (+19.3%) vs. Q1 2023
New holders
33
97 more added
Sold out
43
111 more reduced

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 305 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ2 2023: $5.60B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2023.

Institutions holding IONS in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Comerica Bank538$60.00%+538New
Fairfield, Bush & Co.4$1640.00%+4New
Cape Investment Advisory, Inc.6$2460.00%−7−53.8%Reduced
Retirement Group, LLC11$4510.00%00.0%Unchanged
Coastal Capital Group, Inc.11$4510.00%+11New
Focused Wealth Management, Inc16$6560.00%00.0%Unchanged
Key Financial Inc19$7800.00%00.0%Unchanged
Rosenberg Matthew Hamilton20$8210.00%00.0%Unchanged
GWM Advisors LLC21$8610.00%+13+162.5%Added
Front Row Advisors LLC20$1.00K0.00%00.0%Unchanged
Valley National Advisers Inc11$1.00K0.00%00.0%Unchanged
Raffa Wealth Management, LLC28$1.15K0.00%00.0%Unchanged
CVA Family Office, LLC30$1.23K0.00%00.0%Unchanged
Kelly Financial Services LLC30$1.23K0.00%00.0%Unchanged
Plante Moran Financial Advisors, LLC40$1.64K0.00%+40New
Cornerstone Planning Group LLC45$1.85K0.00%+45New
Bessemer Group Inc52$2.00K0.00%00.0%Unchanged
Earnest Partners LLC49$2.01K0.00%00.0%Unchanged
Blume Capital Management, Inc.55$2.26K0.00%00.0%Unchanged
Global Retirement Partners, LLC58$2.38K0.00%00.0%Unchanged
Johnson Midwest Financial, LLC59$2.42K0.00%00.0%Unchanged
Parkside Financial Bank & Trust62$2.54K0.00%00.0%Unchanged
Massmutual Trust Co FSB63$2.58K0.00%+27+75.0%Added
Versant Capital Management, Inc66$2.71K0.00%+4+6.5%Added
Stonebridge Capital Advisors LLC69$2.83K0.00%+69New
Raleigh Capital Management Inc.72$2.95K0.00%00.0%Unchanged
Centerpoint Advisors, LLC68$3.00K0.00%00.0%Unchanged
Baker Avenue Asset Management, LP77$3.16K0.00%00.0%Unchanged
Bogart Wealth, LLC85$3.49K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.98$4.02K0.00%+9+10.1%Added
Umb Bank N A101$4.14K0.00%00.0%Unchanged
Bell Investment Advisors, Inc102$4.19K0.00%00.0%Unchanged
Private Trust Co NA110$4.51K0.00%+107+3,566.7%Added
Colonial Trust Co120$4.93K0.00%+38+46.3%Added
Pacifica Partners Inc.150$6.33K0.00%00.0%Unchanged
Carolinas Wealth Consulting LLC161$6.61K0.00%00.0%Unchanged
GPS Wealth Strategies Group, LLC184$7.55K0.00%+65+54.6%Added
Clearstead Advisors, LLC185$7.59K0.00%00.0%Unchanged
AllSquare Wealth Management LLC198$8.03K0.01%00.0%Unchanged
Huntington National Bank199$8.16K0.00%+102+105.2%Added
Quantbot Technologies LP200$8.21K0.00%+200New
Spire Wealth Management210$8.62K0.00%00.0%Unchanged
Covestor Ltd246$10.0K0.01%−2−0.8%Reduced
Farther Finance Advisors, LLC247$10.1K0.00%+91+58.3%Added
Washington Trust Advisors, Inc.258$10.6K0.00%−402−60.9%Reduced
Steward Partners Investment Advisory, LLC266$10.9K0.00%−58−17.9%Reduced
Storebrand Asset Management AS271$11.1K0.00%−11,370−97.7%Reduced
EverSource Wealth Advisors, LLC340$13.9K0.00%+340New
Whittier Trust Co of Nevada Inc341$14.0K0.00%−593−63.5%Reduced
Lindbrook Capital, LLC346$14.2K0.00%+106+44.2%Added
HM Payson & Co360$14.8K0.00%+360New
Banque Cantonale Vaudoise400$16.0K0.00%00.0%Unchanged
Global Trust Asset Management, LLC399$16.4K0.01%00.0%Unchanged
Riverview Trust Co476$19.5K0.02%00.0%Unchanged
Signaturefd, LLC476$19.5K0.00%+254+114.4%Added
Riggs Asset Managment Co. Inc.500$20.5K0.01%00.0%Unchanged
Daiwa Securities Group Inc.515$21.0K0.00%−56−9.8%Reduced
AlphaMark Advisors, LLC500$21.0K0.01%00.0%Unchanged
Allspring Global Investments Holdings, LLC555$22.8K0.00%−376,656−99.9%Reduced
Quadrant Capital Group LLC588$24.1K0.00%−2−0.3%Reduced
Laurel Wealth Advisors LLC600$24.6K0.00%00.0%Unchanged
Parallel Advisors, LLC711$29.2K0.00%+40+6.0%Added
Institutional & Family Asset Management, LLC729$29.9K0.00%−7−1.0%Reduced
Ronald Blue Trust, Inc.849$30.0K0.00%00.0%Unchanged
Glassman Wealth Services739$30.3K0.00%+2+0.3%Added
First Manhattan Co775$31.8K0.00%−775−50.0%Reduced
Archer Investment Corp850$34.9K0.01%00.0%Unchanged
Allworth Financial LP859$35.2K0.00%+66+8.3%Added
Harbour Investments, Inc.900$36.9K0.00%00.0%Unchanged
Kistler-Tiffany Companies, LLC1,281$52.6K0.01%00.0%Unchanged
New England Capital Financial Advisors LLC1,300$53.3K0.04%00.0%Unchanged
IFP Advisors, Inc1,155$53.8K0.00%−814−41.3%Reduced
KBC Group NV1,378$57.0K0.00%00.0%Unchanged
Twin Lakes Capital Management, LLC1,500$61.5K0.04%00.0%Unchanged
Horizon Investments, LLC1,736$71.2K0.00%+397+29.6%Added
Itau Unibanco Holding S.A.1,815$74.5K0.00%−27−1.5%Reduced
China Universal Asset Management Co., Ltd.1,875$76.9K0.02%−62−3.2%Reduced
CWM, LLC2,228$91.0K0.00%+306+15.9%Added
American International Group, Inc.2,455$100.7K0.00%+409+20.0%Added
Fifth Third Bancorp2,500$102.6K0.00%−500−16.7%Reduced
Icon Wealth Partners, LLC2,737$112.3K0.01%−336−10.9%Reduced
Ci Investments Inc.2,908$119.0K0.00%+1,705+141.7%Added
Beaird Harris Wealth Management, LLC5,000$205.2K0.02%00.0%Unchanged
Farallon Capital Management, L.L.C.5,000$205.2K0.00%+5,000New
Lazard Asset Management LLC5,137$209.0K0.00%−1,051−17.0%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.5,100$209.3K0.00%+374+7.9%Added
Regions Financial Corp5,110$209.7K0.00%+5,110New
Buckingham Strategic Wealth, LLC5,125$210.3K0.00%+5,125New
Teza Capital Management LLC5,134$210.6K0.03%+5,134New
M&T Bank Corp5,160$211.7K0.00%+5,160New
Cetera Advisor Networks LLC5,175$212.3K0.00%+5,175New
Kestra Advisory Services, LLC5,198$213.3K0.00%+5,198New
Arden Trust Co5,254$215.0K0.04%−4,907−48.3%Reduced
Voloridge Investment Management, LLC5,348$219.4K0.00%+5,348New
Mercer Global Advisors Inc5,363$220.0K0.00%+5,363New
HRT Financial LP5,483$224.0K0.00%+5,483New
National Asset Management, Inc.5,615$230.4K0.01%−389−6.5%Reduced
Perkins Capital Management Inc5,650$232.0K0.20%00.0%Unchanged
Tower Research Capital LLC (TRC)5,888$241.6K0.01%−9,231−61.1%Reduced
MML Investors Services, LLC5,956$244.0K0.00%+5,956New