Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 315
- −18 vs. Q4 2022
- Shares held
- 131.1M
- +517.1K (+0.4%) vs. Q4 2022
- Total value
- $4.69B
- −$238.7M (−4.8%) vs. Q4 2022
- New holders
- 34
- 87 more added
- Sold out
- 52
- 128 more reduced
6 institutions that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Geode Capital Management, LLC | 2,069,950 | $74.0M | 0.01% | +57,227+2.8% | Added |
| OrbiMed Advisors LLC | 2,124,500 | $75.9M | 1.50% | +130,900+6.6% | Added |
| BVF Inc | 2,560,761 | $91.5M | 3.35% | +1,438,952+128.3% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 2,637,192 | $94.3M | 0.65% | −36,346−1.4% | Reduced |
| Deep Track Capital, LP | 2,834,069 | $101.3M | 4.31% | +1,628,296+135.0% | Added |
| Tweedy, Browne Co LLC | 3,541,046 | $126.6M | 6.89% | −900.0% | Reduced |
| Price T Rowe Associates Inc | 3,934,951 | $140.6M | 0.02% | −357,480−8.3% | Reduced |
| State Street Corp | 4,068,334 | $145.4M | 0.01% | −150,395−3.6% | Reduced |
| Clearbridge Investments, LLC | 5,391,581 | $192.7M | 0.18% | −34,061−0.6% | Reduced |
| BlackRock Inc. | 8,982,246 | $321.0M | 0.01% | −97,311−1.1% | Reduced |
| Bellevue Group AG | 9,511,900 | $340.0M | 4.93% | −232,000−2.4% | Reduced |
| T. Rowe Price Investment Management, Inc. | 13,064,047 | $466.9M | 0.33% | +1,385,788+11.9% | Added |
| Vanguard Group Inc | 13,975,790 | $499.5M | 0.01% | +429,096+3.2% | Added |
| FMR LLC | 21,436,334 | $766.1M | 0.07% | +128,815+0.6% | Added |
| Quilter Plc | 363 | – | – | +363 | New |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −330,724−100.0% | Sold out |
| Redmile Group, LLC | 0 | $0 | 0.00% | −266,187−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −197,009−100.0% | Sold out |
| Natixis | 0 | $0 | 0.00% | −159,678−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −128,070−100.0% | Sold out |
| Healthcare of Ontario Pension Plan Trust Fund | 0 | $0 | 0.00% | −63,000−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −60,895−100.0% | Sold out |
| Duality Advisers, LP | 0 | $0 | 0.00% | −53,524−100.0% | Sold out |
| Gateway Investment Advisers LLC | 0 | $0 | 0.00% | −51,174−100.0% | Sold out |
| Intech Investment Management LLC | 0 | $0 | 0.00% | −50,510−100.0% | Sold out |
| Rhenman & Partners Asset Management AB | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −30,709−100.0% | Sold out |
| Toronto Dominion Bank | 0 | $0 | 0.00% | −30,706−100.0% | Sold out |
| Edgestream Partners, L.P. | 0 | $0 | 0.00% | −27,393−100.0% | Sold out |
| Pinebridge Investments, L.P. | 0 | $0 | 0.00% | −26,959−100.0% | Sold out |
| STRS Ohio | 0 | $0 | 0.00% | −25,791−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −25,580−100.0% | Sold out |
| Cantor Fitzgerald, L. P. | 0 | $0 | 0.00% | −22,880−100.0% | Sold out |
| Kestra Advisory Services, LLC | 0 | $0 | 0.00% | −22,413−100.0% | Sold out |
| Echo Street Capital Management LLC | 0 | $0 | 0.00% | −19,103−100.0% | Sold out |
| American Trust | 0 | $0 | 0.00% | −15,970−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −15,463−100.0% | Sold out |
| Quantedge Capital Pte Ltd | 0 | $0 | 0.00% | −15,100−100.0% | Sold out |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −15,018−100.0% | Sold out |
| Teza Capital Management LLC | 0 | $0 | 0.00% | −12,624−100.0% | Sold out |
| Hanseatic Management Services Inc | 0 | $0 | 0.00% | −10,811−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −10,512−100.0% | Sold out |
| Grantham, Mayo, Van Otterloo & Co. LLC | 0 | $0 | 0.00% | −9,700−100.0% | Sold out |
| ETF Managers Group, LLC | 0 | $0 | 0.00% | −7,649−100.0% | Sold out |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −7,569−100.0% | Sold out |
| Calamos Advisors LLC | 0 | $0 | 0.00% | −7,026−100.0% | Sold out |
| Sherbrooke Park Advisers LLC | 0 | $0 | 0.00% | −7,000−100.0% | Sold out |
| Oversea-Chinese Banking CORP Ltd | 0 | $0 | 0.00% | −6,840−100.0% | Sold out |
| Stonegate Investment Group, LLC | 0 | $0 | 0.00% | −6,807−100.0% | Sold out |
| MQS Management LLC | 0 | $0 | 0.00% | −6,547−100.0% | Sold out |
| Seven Eight Capital, LP | 0 | $0 | 0.00% | −5,990−100.0% | Sold out |
| Cetera Advisor Networks LLC | 0 | $0 | 0.00% | −5,672−100.0% | Sold out |
| Regions Financial Corp | 0 | $0 | 0.00% | −5,346−100.0% | Sold out |
| Sectoral Asset Management Inc | 0 | $0 | 0.00% | −4,450−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −3,200−100.0% | Sold out |
| Chiron Investment Management, LLC | 0 | $0 | 0.00% | −3,173−100.0% | Sold out |
| Rockefeller Capital Management L.P. | 0 | $0 | 0.00% | −2,581−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −1,316−100.0% | Sold out |
| Romano Brothers and Company | 0 | $0 | 0.00% | −1,148−100.0% | Sold out |
| Altshuler Shaham Ltd | 0 | $0 | 0.00% | −695−100.0% | Sold out |
| Zullo Investment Group, Inc. | 0 | $0 | 0.00% | −682−100.0% | Sold out |
| Insight Financial Services | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| Hall Laurie J Trustee | 0 | $0 | 0.00% | −115−100.0% | Sold out |
| Affiance Financial, LLC | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Capital Advisors, Ltd. LLC | 0 | $0 | 0.00% | −63−100.0% | Sold out |
| Concord Wealth Partners | 0 | $0 | 0.00% | −36−100.0% | Sold out |
| Hexagon Capital Partners LLC | 0 | $0 | 0.00% | −9−100.0% | Sold out |
| Comerica Bank | – | – | – | – | Not filed |
| Alpha Paradigm Partners, LLC | – | – | – | – | Not filed |
| Heritage Wealth Management, LLC | – | – | – | – | Not filed |
| Semmax Financial Advisors Inc. | – | – | – | – | Not filed |
| Cornerstone Planning Group LLC | – | – | – | – | Not filed |
| CoreCap Advisors, LLC | – | – | – | – | Not filed |