Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 315
- −18 vs. Q4 2022
- Shares held
- 131.1M
- +517.1K (+0.4%) vs. Q4 2022
- Total value
- $4.69B
- −$238.7M (−4.8%) vs. Q4 2022
- New holders
- 34
- 87 more added
- Sold out
- 52
- 128 more reduced
6 institutions that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Mariner, LLC | 6,521 | $233.0K | 0.00% | −11,021−62.8% | Reduced |
| HSBC Holdings PLC | 6,623 | $234.2K | 0.00% | +6,623 | New |
| Baird Financial Group, Inc. | 6,783 | $242.4K | 0.00% | −110−1.6% | Reduced |
| Northwestern Mutual Wealth Management Co | 6,902 | $246.7K | 0.00% | −15−0.2% | Reduced |
| Bridgefront Capital, LLC | 7,056 | $252.2K | 0.15% | +7,056 | New |
| Tanaka Capital Management Inc | 7,112 | $254.0K | 0.74% | 00.0% | Unchanged |
| Delphia (USA) Inc. | 7,326 | $261.8K | 0.32% | −4,286−36.9% | Reduced |
| Stephens Inc | 7,342 | $262.4K | 0.01% | +339+4.8% | Added |
| Utah Retirement Systems | 7,500 | $268.1K | 0.00% | 00.0% | Unchanged |
| Commerce Bank | 7,546 | $269.7K | 0.00% | −196−2.5% | Reduced |
| Northeast Financial Consultants Inc | 7,740 | $276.9K | 0.02% | 00.0% | Unchanged |
| Virtus ETF Advisers LLC | 8,044 | $287.5K | 0.16% | +144+1.8% | Added |
| MetLife Investment Management | 8,100 | $289.5K | 0.00% | +18+0.2% | Added |
| The PNC Financial Services Group, Inc. | 8,381 | $299.5K | 0.00% | −886−9.6% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 8,474 | $303.0K | 0.00% | −1,081−11.3% | Reduced |
| Nicollet Investment Management, Inc. | 8,465 | $303.0K | 0.16% | +527+6.6% | Added |
| Wrapmanager Inc | 8,673 | $310.0K | 0.10% | +174+2.0% | Added |
| Ameriprise Financial Inc | 8,917 | $318.7K | 0.00% | −4,414−33.1% | Reduced |
| Corton Capital Inc. | 9,040 | $323.1K | 0.22% | −3,598−28.5% | Reduced |
| Gsa Capital Partners LLP | 9,422 | $337.0K | 0.03% | +9,422 | New |
| Captrust Financial Advisors | 9,458 | $338.0K | 0.00% | −70−0.7% | Reduced |
| Advisor Group Holdings, Inc. | 9,535 | $341.0K | 0.00% | −1,294−11.9% | Reduced |
| Vontobel Holding Ltd. | 9,816 | $350.8K | 0.00% | −1,113−10.2% | Reduced |
| ProShare Advisors LLC | 9,911 | $354.2K | 0.00% | −3,992−28.7% | Reduced |
| Waddell & Associates, LLC | 10,042 | $358.9K | 0.06% | 00.0% | Unchanged |
| Arden Trust Co | 10,161 | $363.0K | 0.07% | −1,549−13.2% | Reduced |
| Franklin Resources Inc | 10,400 | $371.7K | 0.00% | −3,319−24.2% | Reduced |
| Maryland State Retirement & Pension System | 10,950 | $391.4K | 0.01% | 00.0% | Unchanged |
| Oppenheimer Asset Management Inc. | 11,055 | $395.1K | 0.01% | +686+6.6% | Added |
| Plancorp, LLC | 11,157 | $398.8K | 0.02% | −55−0.5% | Reduced |
| Capital Fund Management S.A. | 11,314 | $404.4K | 0.01% | +11,314 | New |
| E Fund Management Co., Ltd. | 11,372 | $406.0K | 0.03% | +100+0.9% | Added |
| HighTower Advisors, LLC | 11,469 | $409.0K | 0.00% | +303+2.7% | Added |
| Brown Advisory Inc | 11,461 | $409.6K | 0.00% | −70−0.6% | Reduced |
| Storebrand Asset Management AS | 11,641 | $416.0K | 0.00% | −1,421−10.9% | Reduced |
| Illinois Municipal Retirement Fund | 11,866 | $424.0K | 0.01% | 00.0% | Unchanged |
| Bleakley Financial Group, LLC | 12,247 | $437.7K | 0.01% | −937−7.1% | Reduced |
| Sawtooth Solutions, LLC | 12,247 | $437.7K | 0.01% | +12,247 | New |
| AtonRa Partners | 12,344 | $441.2K | 0.64% | −1,531−11.0% | Reduced |
| Inceptionr LLC | 12,790 | $457.1K | 0.15% | +12,790 | New |
| Horizon Kinetics Asset Management LLC | 13,000 | $464.6K | 0.01% | +5,000+62.5% | Added |
| Lincoln National Corp | 13,034 | $465.8K | 0.01% | −65−0.5% | Reduced |
| American Century Companies Inc | 13,163 | $470.4K | 0.00% | −17,709−57.4% | Reduced |
| Gotham Asset Management, LLC | 13,233 | $472.9K | 0.01% | −56,663−81.1% | Reduced |
| Westmount Partners, LLC | 13,462 | $481.1K | 0.22% | 00.0% | Unchanged |
| Creative Planning | 13,632 | $487.2K | 0.00% | +204+1.5% | Added |
| North Star Asset Management Inc | 13,680 | $488.9K | 0.03% | 00.0% | Unchanged |
| Martingale Asset Management L P | 13,943 | $498.3K | 0.01% | +3,582+34.6% | Added |
| Blair William & Co | 14,644 | $523.4K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 15,119 | $540.0K | 0.02% | +7,847+107.9% | Added |
| Neuberger Berman Group LLC | 15,132 | $540.8K | 0.00% | +4,147+37.8% | Added |
| Victory Capital Management Inc | 15,439 | $551.8K | 0.00% | −348−2.2% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 15,571 | $556.5K | 0.00% | +15,571 | New |
| Natixis Advisors, L.P. | 16,076 | $575.0K | 0.00% | −127−0.8% | Reduced |
| US Bancorp | 16,122 | $576.2K | 0.00% | +1,302+8.8% | Added |
| Xponance, Inc. | 17,927 | $640.7K | 0.01% | +217+1.2% | Added |
| Koss-Olinger Consulting, LLC | 18,268 | $653.0K | 0.08% | −295−1.6% | Reduced |
| Federated Hermes, Inc. | 18,473 | $660.2K | 0.00% | −8,106−30.5% | Reduced |
| Handelsbanken Fonder AB | 18,511 | $662.0K | 0.00% | 00.0% | Unchanged |
| Skandinaviska Enskilda Banken AB (publ) | 18,856 | $674.0K | 0.00% | −880−4.5% | Reduced |
| Vestmark Advisory Solutions, Inc. | 19,067 | $681.5K | 0.03% | +465+2.5% | Added |
| Van Eck Associates Corp | 19,175 | $685.0K | 0.00% | +7,133+59.2% | Added |
| Castle Rock Wealth Management, LLC | 19,385 | $692.0K | 0.25% | 00.0% | Unchanged |
| Public Employees Retirement Association of Colorado | 19,604 | $701.0K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 20,012 | $715.2K | 0.00% | +1,315+7.0% | Added |
| Commonwealth Equity Services, LLC | 20,638 | $737.0K | 0.00% | −66−0.3% | Reduced |
| Bayesian Capital Management, LP | 21,227 | $758.7K | 0.09% | +21,227 | New |
| Virginia Retirement Systems Et Al | 22,900 | $818.4K | 0.01% | −7,900−25.6% | Reduced |
| Two Sigma Investments, LP | 23,080 | $824.9K | 0.00% | −178,187−88.5% | Reduced |
| Magnetar Financial LLC | 23,652 | $845.3K | 0.02% | −10,945−31.6% | Reduced |
| Raymond James Financial Services Advisors, Inc. | 25,652 | $916.8K | 0.00% | −1,073−4.0% | Reduced |
| Massachusetts Financial Services Co | 27,153 | $970.4K | 0.00% | +27,153 | New |
| Assenagon Asset Management S.A. | 27,185 | $971.6K | 0.00% | −414,617−93.8% | Reduced |
| Caption Management, LLC | 27,200 | $972.1K | 0.21% | +14,200+109.2% | Added |
| Great West Life Assurance Co | 27,422 | $983.0K | 0.00% | +1,282+4.9% | Added |
| Amalgamated Bank | 29,108 | $1.04M | 0.01% | −2,987−9.3% | Reduced |
| Bard Financial Services, Inc. | 31,825 | $1.14M | 0.09% | −22,100−41.0% | Reduced |
| Grandfield & Dodd, LLC | 32,284 | $1.15M | 0.08% | +810+2.6% | Added |
| Janney Montgomery Scott LLC | 32,608 | $1.17M | 0.00% | −450−1.4% | Reduced |
| Trexquant Investment LP | 32,612 | $1.17M | 0.03% | −14,333−30.5% | Reduced |
| Estate Counselors, LLC | 33,110 | $1.18M | 0.16% | +33,110 | New |
| Engineers Gate Manager LP | 34,340 | $1.23M | 0.05% | +14,363+71.9% | Added |
| Principal Financial Group Inc | 34,666 | $1.24M | 0.00% | −3,656−9.5% | Reduced |
| Envestnet Asset Management Inc | 35,489 | $1.27M | 0.00% | +60+0.2% | Added |
| Profund Advisors LLC | 36,409 | $1.30M | 0.08% | +20,564+129.8% | Added |
| Arizona State Retirement System | 37,043 | $1.32M | 0.01% | +996+2.8% | Added |
| Highland Capital Management, LLC | 37,598 | $1.34M | 0.10% | −2,712−6.7% | Reduced |
| Teacher Retirement System of Texas | 39,383 | $1.41M | 0.01% | +1,005+2.6% | Added |
| Capital Counsel LLC | 40,230 | $1.44M | 0.08% | 00.0% | Unchanged |
| Bank of Nova Scotia | 41,406 | $1.48M | 0.00% | +10,406+33.6% | Added |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.50M | 0.23% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 42,209 | $1.51M | 0.01% | −223,589−84.1% | Reduced |
| International Biotechnology Trust PLC | 43,000 | $1.54M | 0.43% | +43,000 | New |
| Millennium Management LLC | 45,363 | $1.62M | 0.00% | −70,143−60.7% | Reduced |
| Deutsche Bank AG | 45,726 | $1.63M | 0.00% | −20,899−31.4% | Reduced |
| SEI Investments Co | 45,924 | $1.64M | 0.00% | −170.0% | Reduced |
| Ensign Peak Advisors, Inc | 46,310 | $1.66M | 0.00% | −8,581−15.6% | Reduced |
| Private Advisor Group, LLC | 48,467 | $1.73M | 0.02% | −2,541−5.0% | Reduced |
| Alliancebernstein L.P. | 48,600 | $1.74M | 0.00% | −9,904−16.9% | Reduced |
| Erste Asset Management GmbH | 51,300 | $1.79M | 0.03% | 00.0% | Unchanged |