Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 350
- −1 vs. Q2 2022
- Shares held
- 126.4M
- +1.80M (+1.4%) vs. Q2 2022
- Total value
- $5.59B
- +$976.9M (+21.2%) vs. Q2 2022
- New holders
- 50
- 97 more added
- Sold out
- 51
- 130 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Stifel Financial Corp | 300,013 | $13.3M | 0.02% | −6,307−2.1% | Reduced |
| Dowling & Yahnke LLC | 302,571 | $13.4M | 0.62% | 00.0% | Unchanged |
| Swiss National Bank | 302,600 | $13.4M | 0.01% | +3,300+1.1% | Added |
| California Public Employees Retirement System | 323,586 | $14.3M | 0.01% | +41,204+14.6% | Added |
| Baillie Gifford & Co | 324,842 | $14.4M | 0.01% | +13,827+4.4% | Added |
| Nuveen Asset Management, LLC | 339,284 | $15.0M | 0.01% | −9,402−2.7% | Reduced |
| Bank of Montreal | 323,529 | $15.1M | 0.01% | +91,537+39.5% | Added |
| Nikko Asset Management Americas, Inc. | 437,176 | $16.0M | 0.20% | −30,940−6.6% | Reduced |
| Nomura Holdings Inc | 387,908 | $17.1M | 0.17% | +11,931+3.2% | Added |
| Woodline Partners LP | 406,483 | $18.0M | 0.26% | +276,575+212.9% | Added |
| Redmile Group, LLC | 407,659 | $18.0M | 0.70% | +407,659 | New |
| Citadel Advisors LLC | 418,232 | $18.5M | 0.02% | −61,911−12.9% | Reduced |
| Royal Bank of Canada | 436,824 | $19.3M | 0.01% | +8,401+2.0% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 437,176 | $19.3M | 0.02% | −30,940−6.6% | Reduced |
| Candriam Luxembourg S.C.A. | 451,351 | $20.0M | 0.14% | −119,341−20.9% | Reduced |
| Assenagon Asset Management S.A. | 452,760 | $20.0M | 0.09% | +112,044+32.9% | Added |
| Pinnacle Associates Ltd | 500,890 | $22.2M | 0.51% | −14,969−2.9% | Reduced |
| Barclays PLC | 504,488 | $22.3M | 0.02% | +149,909+42.3% | Added |
| Jacobs Levy Equity Management, Inc | 511,975 | $22.6M | 0.18% | −104,791−17.0% | Reduced |
| Bank of America Corp | 559,956 | $24.8M | 0.00% | −48,596−8.0% | Reduced |
| Dimensional Fund Advisors LP | 560,928 | $24.8M | 0.01% | −24,120−4.1% | Reduced |
| Bank of New York Mellon Corp | 579,413 | $25.6M | 0.01% | −85,903−12.9% | Reduced |
| Northern Trust Corp | 623,640 | $27.6M | 0.01% | −1,832−0.3% | Reduced |
| Two Sigma Advisers, LP | 657,511 | $29.1M | 0.08% | −48,300−6.8% | Reduced |
| Wells Fargo & Company | 689,872 | $30.5M | 0.01% | −34,123−4.7% | Reduced |
| Morgan Stanley | 696,538 | $30.8M | 0.00% | −41,439−5.6% | Reduced |
| OrbiMed Advisors LLC | 768,900 | $34.0M | 0.68% | +315,500+69.6% | Added |
| TD Asset Management Inc | 804,083 | $35.6M | 0.04% | +419+0.1% | Added |
| Macquarie Group Ltd | 834,041 | $37.0M | 0.05% | +800,773+2,407.0% | Added |
| Renaissance Technologies LLC | 867,714 | $38.4M | 0.05% | +252,900+41.1% | Added |
| Thrivent Financial for Lutherans | 908,479 | $40.2M | 0.11% | −368,304−28.8% | Reduced |
| JPMorgan Chase & Co | 928,752 | $41.1M | 0.01% | −110,818−10.7% | Reduced |
| Swedbank AB | 1,021,429 | $45.2M | 0.11% | −852−0.1% | Reduced |
| Norges Bank | 1,190,751 | $52.7M | 0.01% | +72,410+6.5% | Added |
| Charles Schwab Investment Management Inc | 1,202,346 | $53.2M | 0.02% | +48,321+4.2% | Added |
| Goldman Sachs Group Inc | 1,290,565 | $57.1M | 0.02% | +248,741+23.9% | Added |
| Geode Capital Management, LLC | 1,901,143 | $84.1M | 0.01% | +36,010+1.9% | Added |
| Camber Capital Management LP | 1,925,000 | $85.1M | 2.85% | −775,000−28.7% | Reduced |
| First Trust Advisors LP | 2,077,260 | $91.9M | 0.12% | +481,205+30.1% | Added |
| Tweedy, Browne Co LLC | 2,722,988 | $120.4M | 5.30% | −3,790−0.1% | Reduced |
| BVF Inc | 2,872,953 | $127.1M | 5.25% | +1,596,379+125.1% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 3,713,107 | $164.2M | 1.14% | −988,190−21.0% | Reduced |
| State Street Corp | 3,760,955 | $166.3M | 0.01% | −441,919−10.5% | Reduced |
| Price T Rowe Associates Inc | 4,797,132 | $212.2M | 0.03% | −10,258,914−68.1% | Reduced |
| Clearbridge Investments, LLC | 5,773,892 | $255.4M | 0.26% | −231,926−3.9% | Reduced |
| BlackRock Inc. | 8,936,062 | $395.2M | 0.01% | +104,672+1.2% | Added |
| Bellevue Group AG | 9,463,400 | $418.6M | 6.01% | −313,128−3.2% | Reduced |
| T. Rowe Price Investment Management, Inc. | 11,156,695 | $493.5M | 0.39% | +11,156,695 | New |
| Vanguard Group Inc | 12,806,023 | $566.4M | 0.02% | +605,747+5.0% | Added |
| FMR LLC | 21,291,159 | $941.7M | 0.10% | +21,599+0.1% | Added |
| Caisse de Depot Et Placement du Quebec | 0 | $0 | 0.00% | −198,324−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −155,533−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −122,897−100.0% | Sold out |
| Ergoteles LLC | 0 | $0 | 0.00% | −69,124−100.0% | Sold out |
| PDT Partners, LLC | 0 | $0 | 0.00% | −59,865−100.0% | Sold out |
| Employees Retirement System of Texas | 0 | $0 | 0.00% | −54,409−100.0% | Sold out |
| HSBC Holdings PLC | 0 | $0 | 0.00% | −47,206−100.0% | Sold out |
| Winton Group Ltd | 0 | $0 | 0.00% | −42,634−100.0% | Sold out |
| Arrowstreet Capital, Limited Partnership | 0 | $0 | 0.00% | −41,104−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −34,626−100.0% | Sold out |
| MML Investors Services, LLC | 0 | $0 | 0.00% | −29,479−100.0% | Sold out |
| Cordatus Wealth Management LLC | 0 | $0 | 0.00% | −26,083−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −22,794−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −18,310−100.0% | Sold out |
| Cetera Advisor Networks LLC | 0 | $0 | 0.00% | −17,276−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −15,947−100.0% | Sold out |
| Oppenheimer & Co Inc | 0 | $0 | 0.00% | −14,560−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −13,185−100.0% | Sold out |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −11,299−100.0% | Sold out |
| Maryland State Retirement & Pension System | 0 | $0 | 0.00% | −9,956−100.0% | Sold out |
| Bridgewater Associates, LP | 0 | $0 | 0.00% | −9,779−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −9,531−100.0% | Sold out |
| Bayesian Capital Management, LP | 0 | $0 | 0.00% | −9,063−100.0% | Sold out |
| Aristides Capital LLC | 0 | $0 | 0.00% | −6,891−100.0% | Sold out |
| Old Mission Capital LLC | 0 | $0 | 0.00% | −6,582−100.0% | Sold out |
| First Foundation Advisors | 0 | $0 | 0.00% | −6,412−100.0% | Sold out |
| Parametrica Management Ltd | 0 | $0 | 0.00% | −6,165−100.0% | Sold out |
| Berkshire Asset Management LLC | 0 | $0 | 0.00% | −5,596−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −5,475−100.0% | Sold out |
| Mercer Global Advisors Inc | 0 | $0 | 0.00% | −5,396−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −4,654−100.0% | Sold out |
| NuWave Investment Management, LLC | 0 | $0 | 0.00% | −3,434−100.0% | Sold out |
| Canada Pension Plan Investment Board | 0 | $0 | 0.00% | −3,124−100.0% | Sold out |
| Captrust Financial Advisors | 0 | $0 | 0.00% | −1,429−100.0% | Sold out |
| International Biotechnology Trust PLC | 0 | $0 | 0.00% | −1,703−100.0% | Sold out |
| Heritage Financial Services, LLC | 0 | $0 | 0.00% | −900−100.0% | Sold out |
| Elequin Capital LP | 0 | $0 | 0.00% | −532−100.0% | Sold out |
| Nisa Investment Advisors, LLC | 0 | $0 | 0.00% | −359−100.0% | Sold out |
| Gables Capital Management Inc. | 0 | $0 | 0.00% | −275−100.0% | Sold out |
| WFA of San Diego, LLC | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| Benjamin F. Edwards & Company, Inc. | 0 | $0 | 0.00% | −119−100.0% | Sold out |
| Gradient Investments LLC | 0 | $0 | 0.00% | −91−100.0% | Sold out |
| Global Wealth Management Investment Advisory, Inc. | 0 | $0 | 0.00% | −80−100.0% | Sold out |
| Concord Wealth Partners | 0 | $0 | 0.00% | −82−100.0% | Sold out |
| Venture Visionary Partners LLC | 0 | $0 | 0.00% | −63−100.0% | Sold out |
| Rockbridge Investment Management, LCC | 0 | $0 | 0.00% | −58−100.0% | Sold out |
| Sargent Bickham Lagudis LLC | 0 | $0 | 0.00% | −43−100.0% | Sold out |
| CoreCap Advisors, LLC | 0 | $0 | 0.00% | −64−100.0% | Sold out |
| First Bank & Trust | 0 | $0 | 0.00% | −15−100.0% | Sold out |
| Patriot Financial Group Insurance Agency, LLC | 0 | $0 | 0.00% | −18−100.0% | Sold out |