Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 351
- +22 vs. Q1 2022
- Shares held
- 124.6M
- +27.5K (0.0%) vs. Q1 2022
- Total value
- $4.61B
- −$315.6K (0.0%) vs. Q1 2022
- New holders
- 53
- 89 more added
- Sold out
- 31
- 130 more reduced
4 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Commonwealth Equity Services, LLC | 23,764 | $879.0K | 0.00% | −2,229−8.6% | Reduced |
| Ensign Peak Advisors, Inc | 24,870 | $921.0K | 0.00% | 00.0% | Unchanged |
| Algert Global LLC | 24,900 | $922.0K | 0.07% | +11,556+86.6% | Added |
| Brookstone Capital Management | 25,341 | $941.0K | 0.02% | +2,970+13.3% | Added |
| Cordatus Wealth Management LLC | 26,083 | $966.0K | 0.45% | +26,083 | New |
| Federated Hermes, Inc. | 27,237 | $1.01M | 0.00% | +8,875+48.3% | Added |
| Grandfield & Dodd, LLC | 28,276 | $1.05M | 0.08% | +275+1.0% | Added |
| Trexquant Investment LP | 28,423 | $1.05M | 0.05% | −19,339−40.5% | Reduced |
| MML Investors Services, LLC | 29,479 | $1.09M | 0.01% | +1,357+4.8% | Added |
| Janney Montgomery Scott LLC | 30,658 | $1.14M | 0.01% | −7,956−20.6% | Reduced |
| Prospera Financial Services Inc | 31,284 | $1.16M | 0.06% | +26,644+574.2% | Added |
| Deutsche Bank AG | 32,465 | $1.20M | 0.00% | −897−2.7% | Reduced |
| Macquarie Group Ltd | 33,268 | $1.23M | 0.00% | +1,262+3.9% | Added |
| Amalgamated Bank | 33,323 | $1.23M | 0.01% | +1,389+4.3% | Added |
| Arizona State Retirement System | 34,441 | $1.27M | 0.01% | +87+0.3% | Added |
| Simplex Trading, LLC | 34,626 | $1.28M | 0.04% | +30,547+748.9% | Added |
| Knowledge Leaders Capital, LLC | 34,640 | $1.28M | 1.24% | +34,640 | New |
| AlphaCrest Capital Management LLC | 36,447 | $1.35M | 0.07% | −21,845−37.5% | Reduced |
| Susquehanna International Group, LLP | 37,553 | $1.39M | 0.00% | −12,173−24.5% | Reduced |
| ExodusPoint Capital Management, LP | 37,590 | $1.39M | 0.02% | +37,590 | New |
| Koss-Olinger Consulting, LLC | 38,922 | $1.44M | 0.26% | −5,198−11.8% | Reduced |
| Capital Fund Management S.A. | 39,110 | $1.45M | 0.04% | −5,609−12.5% | Reduced |
| Highland Capital Management, LLC | 39,159 | $1.45M | 0.10% | +39,159 | New |
| Envestnet Asset Management Inc | 40,365 | $1.49M | 0.00% | −50,506−55.6% | Reduced |
| Capital Counsel LLC | 41,010 | $1.52M | 0.09% | 00.0% | Unchanged |
| Arrowstreet Capital, Limited Partnership | 41,104 | $1.52M | 0.00% | +41,104 | New |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.55M | 0.25% | 00.0% | Unchanged |
| Winton Group Ltd | 42,634 | $1.58M | 0.08% | +42,634 | New |
| HSBC Holdings PLC | 47,206 | $1.78M | 0.00% | +40,609+615.6% | Added |
| Rhenman & Partners Asset Management AB | 50,000 | $1.85M | 0.21% | −21,000−29.6% | Reduced |
| Erste Asset Management GmbH | 51,300 | $1.93M | 0.04% | 00.0% | Unchanged |
| Raymond James Financial Services Advisors, Inc. | 54,230 | $2.01M | 0.00% | +3,645+7.2% | Added |
| Employees Retirement System of Texas | 54,409 | $2.01M | 0.03% | +22,000+67.9% | Added |
| Voya Investment Management LLC | 56,555 | $2.09M | 0.01% | −7,710−12.0% | Reduced |
| Treasurer of the State of North Carolina | 59,742 | $2.21M | 0.01% | +8,071+15.6% | Added |
| PDT Partners, LLC | 59,865 | $2.22M | 0.20% | −20,205−25.2% | Reduced |
| Alliancebernstein L.P. | 60,860 | $2.25M | 0.00% | −1,079−1.7% | Reduced |
| Graham Capital Management, L.P. | 61,013 | $2.26M | 0.10% | +40,913+203.5% | Added |
| Gotham Asset Management, LLC | 61,484 | $2.28M | 0.07% | +23,057+60.0% | Added |
| UBS Oconnor LLC | 61,497 | $2.28M | 0.02% | +61,497 | New |
| Occudo Quantitative Strategies LP | 61,671 | $2.28M | 0.19% | +61,671 | New |
| Guggenheim Capital LLC | 63,746 | $2.36M | 0.02% | −4,491−6.6% | Reduced |
| Ergoteles LLC | 69,124 | $2.56M | 0.08% | +31,124+81.9% | Added |
| Eaton Vance Management | 69,598 | $2.58M | 0.00% | +13,033+23.0% | Added |
| SG Americas Securities, LLC | 72,557 | $2.69M | 0.04% | +60,966+526.0% | Added |
| PFS Investments Inc. | 74,125 | $2.74M | 0.06% | −936−1.2% | Reduced |
| Tudor Investment Corp Et Al | 74,192 | $2.75M | 0.08% | +44,667+151.3% | Added |
| Public Employees Retirement System of Ohio | 75,343 | $2.79M | 0.01% | −2,323−3.0% | Reduced |
| State of New Jersey Common Pension Fund D | 80,433 | $2.98M | 0.01% | −8,446−9.5% | Reduced |
| LPL Financial LLC | 82,087 | $3.04M | 0.00% | −12,466−13.2% | Reduced |
| Davenport & Co LLC | 83,318 | $3.08M | 0.03% | −545−0.6% | Reduced |
| Alps Advisors Inc | 84,115 | $3.11M | 0.03% | −61,500−42.2% | Reduced |
| Eversept Partners, LP | 86,311 | $3.20M | 0.31% | −72,495−45.7% | Reduced |
| Jane Street Group, LLC | 90,889 | $3.36M | 0.01% | +63,098+227.0% | Added |
| Bard Financial Services, Inc. | 93,445 | $3.46M | 0.32% | −5,575−5.6% | Reduced |
| Manufacturers Life Insurance Company, The | 93,214 | $3.50M | 0.00% | +17,916+23.8% | Added |
| Gateway Investment Advisers LLC | 99,129 | $3.67M | 0.04% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 99,234 | $3.67M | 0.01% | −184,896−65.1% | Reduced |
| Eventide Asset Management, LLC | 110,000 | $4.07M | 0.09% | +110,000 | New |
| Principal Financial Group Inc | 112,168 | $4.15M | 0.00% | +81,957+271.3% | Added |
| Jump Financial, LLC | 114,857 | $4.25M | 0.18% | +5,030+4.6% | Added |
| Rafferty Asset Management, LLC | 119,283 | $4.42M | 0.04% | −59,511−33.3% | Reduced |
| Kennedy Capital Management, Inc. | 119,682 | $4.43M | 0.12% | +109,834+1,115.3% | Added |
| BNP Paribas Arbitrage, SA | 119,970 | $4.44M | 0.01% | +29,034+31.9% | Added |
| HRT Financial LP | 122,897 | $4.55M | 0.05% | +13,521+12.4% | Added |
| DekaBank Deutsche Girozentrale | 124,776 | $4.65M | 0.01% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 126,621 | $4.69M | 0.01% | +126,621 | New |
| Woodline Partners LP | 129,908 | $4.81M | 0.08% | −62,743−32.6% | Reduced |
| Squarepoint Ops LLC | 129,940 | $4.81M | 0.04% | +111,046+587.7% | Added |
| Schonfeld Strategic Advisors LLC | 130,023 | $4.81M | 0.05% | +74,480+134.1% | Added |
| Peregrine Capital Management LLC | 130,224 | $4.82M | 0.15% | −96−0.1% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 131,983 | $4.89M | 0.03% | −25,210−16.0% | Reduced |
| State of Wisconsin Investment Board | 137,233 | $5.08M | 0.01% | +22,782+19.9% | Added |
| Private Advisor Group, LLC | 137,782 | $5.10M | 0.05% | −19,186−12.2% | Reduced |
| Fred Alger Management, LLC | 146,656 | $5.43M | 0.03% | +146,656 | New |
| New York State Common Retirement Fund | 146,825 | $5.43M | 0.01% | +250.0% | Added |
| Citigroup Inc | 149,131 | $5.52M | 0.01% | +67,795+83.4% | Added |
| BLB&B Advisors, LLC | 149,250 | $5.53M | 0.44% | −495−0.3% | Reduced |
| Cubist Systematic Strategies, LLC | 149,388 | $5.53M | 0.04% | +53,858+56.4% | Added |
| Credit Suisse AG | 149,721 | $5.54M | 0.01% | −30,905−17.1% | Reduced |
| Rhumbline Advisers | 154,502 | $5.72M | 0.01% | +20,942+15.7% | Added |
| Balyasny Asset Management LLC | 155,533 | $5.76M | 0.02% | +155,533 | New |
| Sonora Investment Management Group, LLC | 156,323 | $5.79M | 0.55% | −938−0.6% | Reduced |
| AXA S.A. | 158,535 | $5.87M | 0.02% | +72,235+83.7% | Added |
| Tocqueville Asset Management L.P. | 162,605 | $6.02M | 0.11% | −4,900−2.9% | Reduced |
| Legal & General Group Plc | 163,954 | $6.07M | 0.00% | +1,636+1.0% | Added |
| State Board of Administration of Florida Retirement System | 164,125 | $6.08M | 0.01% | −6,603−3.9% | Reduced |
| Sector Gamma AS | 165,439 | $6.13M | 1.37% | −23,000−12.2% | Reduced |
| California State Teachers Retirement System | 169,414 | $6.27M | 0.01% | +1,052+0.6% | Added |
| UBS Group AG | 170,167 | $6.30M | 0.00% | −31,034−15.4% | Reduced |
| Parkman Healthcare Partners LLC | 174,300 | $6.45M | 2.38% | +174,300 | New |
| Tekla Capital Management LLC | 175,680 | $6.50M | 0.26% | 00.0% | Unchanged |
| Privium Fund Management B.V. | 180,107 | $6.67M | 2.26% | 00.0% | Unchanged |
| Hudson Bay Capital Management LP | 185,000 | $6.85M | 0.07% | −25,000−11.9% | Reduced |
| Altrinsic Global Advisors LLC | 186,454 | $6.90M | 0.28% | −21,704−10.4% | Reduced |
| Liontrust Investment Partners LLP | 194,492 | $7.20M | 0.10% | +194,492 | New |
| Caisse de Depot Et Placement du Quebec | 198,324 | $7.34M | 0.02% | +198,324 | New |
| Tang Capital Management LLC | 200,000 | $7.40M | 1.12% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 205,789 | $7.62M | 0.00% | −1,117−0.5% | Reduced |
| Pictet Asset Management SA | 238,339 | $8.82M | 0.01% | +32,198+15.6% | Added |